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BY Will Fitzgerald

MD Anderson researchers discussed new data on the connection between body mass index (BMI) and response to presurgical chemotherapy in patients with inflammatory breast cancer during a poster discussion at the 36th annual CTRC-AACR San Antonio Breast Cancer Symposium.

The study examined 1,002 cases of patients with inflammatory breast cancer or locally advanced non-inflammatory breast cancer between 2006-2012. It was the first...

BY Scott Merville

Even as the targeted therapy ibrutinib makes its way through clinical trials as a single treatment for chronic lymphocytic leukemia (CLL),...

BY Judy Overton

In a typical day, each of us swallows 30 milliliters of mucus from our lungs. A mucus blanket is swept from the most distant airways up the...

BY Scott Merville

Patients on an extended clinical trial of the targeted therapy ibrutinib have their relapsed or resistant chronic lymphocytic leukemia stymied even as side effects decline more than two years into the study.

Susan O'Brien, M.D., professor of Leukemia presented a poster updating trial results Monday evening at the 55th American Society of Hematology (ASH) Annual Meeting and Exposition.

It was a busy day for MD Anderson investigators...

BY Scott Merville

When it comes to equipping T cells, the immune system's attack dogs, to find and kill cancer cells, Sleeping Beauty just might be a heroine...

BY Scott Merville

Glioblastoma multiforme, the most common and lethal form of brain cancer, "is one of the science and medical world's hardest nuts to crack...

BY Scott Merville

The U.S. Food and Drug Administration today approved ibrutinib for treatment of patients with mantle cell lymphoma who have received at least...

BY MD Anderson Staff

Oral cancer patients with tumors at the back of the throat are half as likely to require a feeding tube when treated with intensity modulated...

BY MD Anderson Staff

New MD Anderson research published in JAMA Otolaryngology Head and Neck Surgery indicates that oral exercises help patients maintain their...

BY Will Fitzgerald

MD Anderson-led research published in the journal Cancer is shedding light on the risk of second primary malignancies, a leading cause of...

BY Oliver Bogler, Ph.D.

I finished the most active treatment phase for male breast cancer in the first week of June, enjoyed a few weeks off...

BY Scott Merville

In glioblastoma multiforme (GBM), the most common and lethal brain tumor, lack of differentiation makes a big, and bad...

BY Scott Merville

A protein called Skp2, overexpressed in many types of cancer, for years has gotten away with promoting tumor growth and progression unhindered...

BY Katrina Burton

Triple-negative breast cancer cells produce inflammatory cytokines Interleukin-6 (IL-6) and Interleukin-8 (IL-8), which in turn stimulate...

BY MD Anderson Staff

MD Anderson scientists have found a molecular signaling pathway that connects two known contributors to cancer cell growth and survival. They...

BY Laura Sussman

MET protein levels correlate strongly with a cellular transition that occurs in a treatment-resistant type of colorectal cancer, according...

BY Will Fitzgerald

In a large national, cooperative trial led by MD Anderson, researchers determined bevacizumab (Avastin), did not offer survival benefit to...

BY Laura Sussman

Following surgery, radiation and chemotherapy with a drug that hinders formation of tumor-supporting blood vessels does...

BY John Chattaway

Why is our immune system usually not capable of eradicating cancerous tumor cells?

This is the main question that Greg Lizee, Ph.D....

BY Scott Merville

The epidermal growth factor receptor (EGFR) often goes haywire in cancer, sending constant, urgent signals into a cell, telling it to grow...

BY Katrina Burton

The U.S. Centers for Disease Control and Prevention estimates obesity to be a contributing factor to millions of dollars in health care costs...

BY Scott Merville

A pivotal protein leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis (MS) and potentially...

BY Scott Merville

"Cancer is a complex and heterogeneous disease driven by gene mutations. As we enter the era of personalized medicine, the characterization...

BY Scott Merville

MD Anderson scientists Jim Allison and Hagop Kantarjian, at left, and Guillermina Lozano and Gabriel Hortobagyi, at right, won four of 14...

BY Scott Merville

The first of six awards to scientists at The University of Texas MD Anderson Cancer Center at this year's AACR Annual Meeting 2013 went to...

BY Sarah Adai

Actin is a protein that has been long known to work by linking itself into chains to form filaments. Providing rigidity to the cell, actin...

BY Michael Rytting, Sara Farris

Recently, the U.S. Food and Drug Administration (FDA) approved the use of Gleevec in combination with chemotherapy to treat newly diagnosed...

BY Scott Merville

For years, scientists have crafted vaccines designed to treat cancer, rather than to prevent it, by priming the immune system to track down...

BY Katrina Burton

Smoking remains the leading cause of preventable illness and death in the United States, so the health benefits of quitting are substantial...

BY William Fitzgerald

Gordon Mills, M.D., Ph.D., recalls a proposal he wrote 18 years ago detailing the concept of personalized cancer therapy and its potential...

BY Scott Merville

A phase 2 clinical trial of a targeted therapy provides evidence that there might, at last, be a treatment that shrinks or stifles the growth...

BY Scott Merville

A key to the perils of endless injury repair, the molecular path from stress through a cancer-promoting gene to ovarian...

BY Sharon Dent, Ph.D., David Johnson, Ph.D., and Sarah Adai

Chromatin, the intertwined histone proteins and DNA that are packaged into chromosomes, has long been recognized as a...

BY Scott Merville

When a crucial enzyme is dotted with targets that summon an attack by a cell's protein-destroying complex, another molecule comes to the rescue...

BY MD Anderson Faculty

By Naoto Ueno M.D., Ph.D.

Each year, on the basis of new basic research discoveries and clinical observations, my research group generates...

BY Scott Merville

Cancer begins when a single cell goes haywire. Now the keys to understanding that cell's transition to lethal tumor may be found in the unprecedented...