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BY Clayton R. Boldt, Ph.D.

An international consortium, led in part by clinicians and researchers from The University of Texas MD Anderson Cancer Center, has published a series of best-practice recommendations for conducting clinical trials for neoadjuvant, or pre-surgical, therapies in patients with locally advanced melanoma.

The report, published in Lancet Oncology, provides recommendations for clinical trial design, including patient inclusion criteria...

Metastatic melanoma cells

BY Scott Merville

Combining two types of drugs that, separately, have extended the lives of people with metastatic melanoma has yielded higher response rates...

BY Jill Russell, Ph.D.

Researchers at The University of Texas MD Anderson Cancer Center have shown how pretreatment clonal complexity in pancreatic tumor cells leads...

BY MD Anderson staff

In October 2018, the Nobel Prize in Physiology or Medicine was awarded to Jim Allison, Ph.D., chair of Immunology, for his discoveries on the biology of T cells, which launched the field of cancer immunotherapy. This new treatment approach, which stimulates the immune system to attack cancer, has saved the lives of many patients with a wide variety of cancer types.

Unfortunately, immunotherapy is not equally effective in all patients...

T cell image

BY Clayton R. Boldt, Ph.D.

Each May, Skin Cancer Awareness Month serves as a reminder of how individuals can work to lower their risk of skin cancer – the most common...

BY Scott Merville

Melanoma cells are able to evade cancer immunotherapy by using a specific protein to hide from immune system T cells out to seek and destroy...

BY Scott Merville

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal...

BY Scott Merville

A pair of targeted therapies given before and after surgery for melanoma produced at least a six-fold increase in time to progression compared...

BY Laura Sussman

High response rates to a pair of combination therapies point to potentially new options for a group of metastatic melanoma patients who have...

BY Scott Merville

Melanoma patients’ response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies...