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BY Clayton Boldt, Ph.D.

Advanced ovarian cancer most commonly metastasizes to the omentum, a layer of fatty tissue that wraps around and protects internal organs in the abdomen, but the reasons for this have not been well-understood. In a new study, MD Anderson researchers discovered that a protein called omentin, or ITLN1, works to prevent metastasis of the cancer cells, but it is lost as the cancer develops.

Their preclinical findings, published in...

Imaging mass spectrometry showing increased abundance of ATP, a cellular energy compound, in the omentum of mice after injection with omentin protein.

BY Jill Russell, Ph.D.

MD Anderson researchers have identified potential biomarkers for the response of high-grade serous ovarian cancers (HGSC) to surgical resection...

BY Clayton Boldt, Ph.D.

Immunotherapies have brought the potential for long-term remission and even cures to patients with many cancer types, but the benefits have...

BY Clayton Boldt, Ph.D.

Results from two The University of Texas MD Anderson Cancer Center-led clinical trials indicate that targeted therapies led to significant improvements in progression-free survival (PFS) and response rates compared to the standard of care for women with certain types of breast and ovarian cancers. These studies were presented today in Barcelona as late-breaking abstracts at the European Society for Medical Oncology Congress 2019. As the...

BY Scott Merville

Using an antibody to plug a protein secreted by fibrous tissues in tumors stifles ovarian and pancreatic cancer in mouse models by reducing...

BY Devon Carter

DNA damage response (DDR) inhibitors, such as poly (ADP-ribose) polymerase (PARP) inhibitors, are a type of targeted therapy used to treat...

BY Clayton R. Boldt, Ph.D.

September is Ovarian Cancer Awareness Month, an annual time to bring attention to the impact of the disease. This year, more than 22,000 women...

BY Scott Merville

When Elizabeth White started a new job as executive director of the Michigan Ovarian Cancer Alliance in 2017, she decided it...

BY Ron Gilmore

A study of high-grade ovarian cancer has shown the enzyme protein kinase C iota (PRKCI) to be an ovarian oncogene, suggesting PRKCI inhibition...

BY Laura Sussman

For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC), hormone maintenance...