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BY Clayton Boldt, Ph.D.

Repurposing FDA-approved therapies is a cost-effective way to bring new treatments to patients in need, but identifying those drugs with benefits in new indications can be a challenging discovery process.

A team of researchers led by MD Anderson and the IRCCS Regina Elena National Cancer Institute in Rome have used a novel computer-aided drug discovery approach to identify decitabine, an FDA approved therapy for myelodysplastic...

Gene expression signature identified in the study allows pancreatic cancers stratification based on KRAS dependency

BY Clayton Boldt, Ph.D.

Leukemia researchers at The University of Texas MD Anderson Cancer Center, working collaboratively with the Therapeutics Discovery division...

BY Ron Gilmore

Researchers in MD Anderson’s Leukemia department played central roles in the studies of two drugs, glasdegib and venetoclax, approved in November...

BY Clayton R. Boldt, Ph.D.

MD Anderson’s Moon Shots Program™ was established to bring teams of world-class clinicians and researchers together in order to rapidly advance scientific discoveries into the clinic to save patients’ lives. Driving the work of the Moon Shots™ are 10 research platforms that provide unique expertise, technical support and novel infrastructure to the program’s 13 disease-focused initiatives.

One of those platforms is the Cancer Genomics...

DNA gene research

BY Ron Gilmore

Somatic mutations in certain genes may function as a molecular minimal residual disease marker for acute myeloid leukemia (AML), according...

BY Clayton R. Boldt, Ph.D.

Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) encompass a spectrum of diseases characterized by an overproduction of immature...

BY Clayton Boldt, Ph.D.

Older patients with non-metastatic breast cancer who have been treated modern chemotherapy drugs have a greater risk of secondary acute myeloid...

BY Ron Gilmore

Researchers from MD Anderson Cancer Center presented their latest findings involving drug treatments for blood cancers at the American...

BY Clayton Boldt, Ph.D.

It's been five years since MD Anderson launched its Moon Shots Program™, a collaborative effort to more quickly turn scientific discoveries...

BY Ron Gilmore

Tomas Sandoval was about to become a father for the second time in June 2014, when he was devastated to learn he had non-Hodgkin lymphoma...