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BY Ron Gilmore

Just as a driver’s night vision improves by simply cleaning the headlights, scientists at The University of Texas MD Anderson Cancer Center have discovered that removing an unwanted element from a protein known to suppress the immune system may eventually help clinicians better observe which cancer patients will benefit by treatment with immune checkpoint blockades.

Heng-Huan Lee, Ph.D., a postdoctoral fellow and Ying-Nai Wang,...

Glycans attach to the PD-L1 protein on tumors, making it hard to detect. MD Anderson researchers have found that purging glycans makes PD-L1 easier to find and accurately assess. Image courtesy of Cancer Cell.

BY Ronda Wendler

When Craig Bunk began experiencing severe abdominal pain, blood loss and fatigue, his family doctor thought a stomach ulcer was to blame....

BY Scott Merville

A practice-changing clinical trial conceived and led by MD Anderson investigators showed that metastatic colorectal cancer patients with a...

BY Ron Gilmore

Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as “collateral lethality,” which may create new options for development of therapies for several cancers.

Scientists at MD Anderson Cancer Center have discovered that during early cancer development when a common tumor suppressor known as SMAD4 is deleted, a nearby metabolic enzyme gene...

stomach, colon and pancreas illustration

BY Clayton Boldt, Ph.D.

Three years ago, Stephen Cadmus faced a dilemma. He needed to see a doctor, but he had no health insurance.

To get the medical...

BY Laura Sussman

In a first-of-its-kind study, researchers at MD Anderson Cancer Center have demonstrated a benefit in overall survival among epithelial ovarian...

BY Laura Sussman

Thanks to the modern era of new chemotherapeutic and biologic agents available for managing their disease, patients with metastatic colorectal...

BY Laura Sussman

In the next 15 years, more than one in 10 colon cancers and nearly one in four rectal cancers will be diagnosed in patients younger than the...

BY Ron Gilmore

MD Anderson scientists have discovered mutations in a gene that allow tumors to form and grow.

In this month’s issue of Cancer Cell...