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BY Jill Russell, Ph.D.

Glioblastoma is the most common, aggressive and deadly form of brain cancer. Median overall survival for primary glioblastoma is 14.6 months with the standard treatments of surgery, radiation therapy and the chemotherapy temozolomide, and falls to 5.5 – 11 months for recurrent glioblastoma.

Tumor heterogeneity and the blood-brain barrier make it difficult to treat glioblastoma. Immunotherapies such as immune checkpoint inhibitors...

T cells and the brain

BY Scott Merville

A cold virus engineered to attack the most common and deadly of brain tumors allowed 20% of patients with recurrent glioblastoma to live for...

BY Ron Gilmore

Patterns in how genes express themselves may help doctors personalize treatment for glioblastoma, the most deadly of brain cancers, according...

BY Ron Gilmore

There are many moving parts when it comes to the mechanics of how otherwise healthy cells are transformed into those that cause deadly cancers such as glioblastoma.

Research led by Zhimin Lu, Ph.D., professor of Neuro-Oncology at MD Anderson Cancer Center, has revealed new insight into how the enzyme RNF8 mediates the protein histone 3 (H3) to promote glycolysis and the formation of tumors. The results of the study were published...

BY Bryan Tutt

The most common malignant brain tumors in children, medulloblastomas, are usually incurable if they recur. Even with surgery, chemotherapy...

BY Ron Gilmore

Researchers at MD Anderson have discovered a potentially new therapeutic approach for certain brain cancers in which the enzyme enolase (ENO1...

BY Ronda Wendler

When Allison Easley awoke one morning with soreness under her right armpit, she thought she’d pulled a muscle. But the pain soon became worse...

BY Ron Gilmore

An international study has revealed new information about diffuse glioma, the most common type of tumor found in some 80% of adult brain cancer...

BY Scott Merville

MD Anderson’s Moon Shots Program has expanded its targets, adding some of the most intractable cancers to its campaign to more rapidly convert...

BY Ron Gilmore

Scientists at MD Anderson Cancer Center may have discovered why some brain cancer patients develop resistance to standard treatments including...