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BY Clayton R. Boldt, Ph.D.

The Therapeutics Discovery division at MD Anderson Cancer Center has advanced a new small-molecule inhibitor of cancer metabolism to Phase I clinical trials. This new drug candidate marks the fourth novel therapeutic brought from concept to clinical trial by Therapeutics Discovery, a drug-discovery engine built within the walls of MD Anderson to eliminate the bottlenecks that hamper traditional drug development.

The drug candidate...

Phil Jones, Ph.D., and Tim Heffernan, Ph.D.

BY Clayton R. Boldt, Ph.D.

Neoadjuvant therapy is treatment, such as chemotherapy or radiation, given before a patient has surgery. This approach is used in many cancer...

BY Devon Carter

DNA damage response (DDR) inhibitors, such as poly (ADP-ribose) polymerase (PARP) inhibitors, are a type of targeted therapy used to treat...

BY Kellie Bramlet Blackburn

In recent years, the surgical technique sentinel lymph node biopsy has allowed surgeons to more accurately determine how far cancer has spread while lowering patient side effects.

It has become the standard of care in treating breast cancer, melanoma and vulvar cancers, and MD Anderson surgeons are leading clinical studies to apply the technique to treat other cancers, including cervical, uterine and head and neck cancers....

cervical cancer metastasis

BY Ron Gilmore

Researchers in MD Anderson’s Leukemia department played central roles in the studies of two drugs, glasdegib and venetoclax, approved in November...

BY Clayton R. Boldt, Ph.D.

Despite a plethora of new and promising treatments available, lung cancer remains the leading cause of cancer death in the United States,...

BY Katie McCallum

Pancreatic cancer is one of the most lethal types of cancer, expected to cause more than 44,000 deaths in the U.S. this year. It’s a deadly...

BY Scott Merville

A study led by MD Anderson found the investigational drug quizartinib prolongs overall survival for patients with a deadly form of acute myeloid...

BY Scott Merville

When Elizabeth White started a new job as executive director of the Michigan Ovarian Cancer Alliance in 2017, she decided it...

BY Michael Hardy

Most people think of hypnosis as a kind of party trick — a mischievous way to make somebody unconsciously do your bidding.

But...