A Phase 1b Open-label Study Investigating theSafety, Tolerability, Pharmacokinetics, andEfficacy of Administration of Blinatumomab inCombination With AMG 404 for the Treatment ofAdults With Relapsed or Refractory B CellPrecursor Acute Lymphoblas
MD Anderson Study Status
Blinatumomab, AMG 404, Dexamethasone Premedication
The primary objective of this phase 1b study is to evaluate the safety and tolerability of blinatumomab and AMG 404 in combination in adults with R/R B-ALL and to estimate the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of AMG 404 when combined with continuous intravenous infusion (cIV) blinatumomab.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Acute Lymphoblastic Leukemia
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