Study #2018-0045
A Phase II, Open-Label Study of ONC201 in Adults with Recurrent High-Grade Glioma
MD Anderson Study Status
Not Accepting
Treatment Agent
ONC201
Description
The primary objective of this phase II trial is to determine the efficacy and safety of ONC201, an oral small molecule imipridone DRD2 antagonist, in adult subjects with recurrent high-grade glioma. This study will test the research hypothesis that histone H3 K27M mutation sensitizes to oral administration of ONC201 in gliomas.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Glioma
Study phase:
II
Physician name:
Nazanin Majd
Department:
Neuro-Oncology
For general questions about clinical trials:
1-877-632-6789
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