IDH1 Mutation Analysis

IDH1 Mutational Analysis


To detect and type mutations in exon 4 of the IDH1 gene for differential diagnosis and prognostic stratification of glial tumors and acute myeloid leukemia.


This test is performed by PCR-based Sanger sequencing of DNA to examine the mutation status of codons 80 to 138 in exon 4 of IDH1.

Test Parameters:  

This assay will detect mutations present in exon 4 of IDH1. The sensitivity of the Sanger sequencing assay is 20% of variant sequence in the background of wild-type sequence.

Turnaround Time:

7-10 days

Sample Requirements:

10 mL peripheral blood, 2-5mL bone marrow aspirate, 5g purified DNA, or 4-10 unstained tissue sections on glass slides along with 1 H&E-stained section.
Please provide a copy of the corresponding pathology report.

CPT Codes:


Additional charges may apply for tissue extraction.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.