A Validation Study Protocol for the Development of the Chinese Version of the Brief Fatigue Inventory and the MD Anderson Symptom Inventory

Principal Investigator: Xin Shelley Wang, M.D., M.P.H.

Common symptoms of cancer and cancer treatment significantly impair the function and quality of life of patients. However, some of them are often under-treated because of lack of a validated instrument. The current status of symptom management for cancer has been studied in some countries, but not in China. The goal of this study is to establish the validation of two symptom assessment instruments and look at symptoms related to cancer and its treatment in Tianjin, China.

Primary Objectives

To establish and validate the Chinese language version of Brief Fatigue Inventory (BFI-C) and MD Anderson Symptom Inventory (MDASI-C)


This validation study included a one-time survey of a sample of outpatients and inpatients with both hematological and solid tumor type diseases at Tianjin Cancer Institute and Hospital in Tianjin, China.


Instruments included the Brief Fatigue Inventory (BFI), the MD Anderson Symptom Inventory (MDASI) and the MOS 36-Item Short-Form Health Survey (SF-36).

For more information

Contact Xin Shelley Wang, M.D., M.P.H., at swong@mdanderson.org