Anesthesiology and Critical Care Research

Research within the Division of Anesthesiology & Critical Care reflects the multidisciplinary nature of the larger institutional research effort. A common theme of much of the division’s research is to improve the management of the patients receiving cancer therapy (surgery and other therapies) and to reduce the post-treatment morbidity and mortality of this therapy.

In 2006, Dr. Hui-Lin Pan, M.D., Ph.D., joined the division as the deputy division head for research. He is a nationally recognized investigator in the fields of pain and neuroscience research. As part of his recruitment, Dr. Pan and the division’s investigators were assigned over 8700 square feet of newly renovated research space in the Bates Freeman Building. The new research space more than doubled the existing research space bringing together, on one floor, all of the division’s basic research scientists.

The division has five principal investigators, Hui-Lin Pan, M.D., Ph.D., Howard Gutstein, M.D., Zhi Zhong Pan, Ph.D., Han-Rong Weng, M.D. and Patrick Dougherty, Ph.D., conducting basic research in pain mechanisms, opioid tolerance and addiction and analgesic pharmaceutical development. The division’s research program has been very productive and enjoys an increasing portfolio of NIH grants, publications and patents.

The division’s clinical research efforts focus on improving perioperative outcome in surgical and critically ill cancer patients. Cancer patients often require surgical procedures that expose them to risks of serious complications and death. The perioperative outcome research program in the division is composed of basic science and clinical investigations to minimize perioperative morbidity and mortality by identifying predictive physiologic and genetic risk factors, to optimize strategies of perioperative care and to more tightly link the operative and recovery periods in patients at greatest risk.