Resources for Clinicians

Geriatric Learning Modules

These six online educational modules cover geriatric issues commonly experienced by older surgical oncology patients. Each module will take about 15 to 20 minutes and will cover introductory information topics including:

  • Pharmacokinetics
  • Hospital hazards
  • Decision-making capacity
  • Appropriate prescribing
  • Delirium
  • Pain management

These geriatric learning modules are available to the general public, but you must have an account with MD Anderson's Sakai education portal. Please read the enrollment instructions before trying to access the modules. 

Recent Abstracts & Publications

Please email requests for PDF copies of publications to Peggy James at

Thyroid Cancer

Lee S, Skelton TS, Zheng F, Schwartz KA, Perrier ND, Lee JE, Bassett RL, Ahmed S, Krishnamurthy S, Busaidy NL, Grubbs EG. The biopsy-proven benign thyroid nodule: is long-term follow-up necessary? J Am Coll Surg 217:81-88, 2013.

Morris LF, Waguespack SG, Warneke CL, Ryu H, Ying AK, Anderson BJ, Sturgis EM, Clayman GL, Lee JE, Evans DB, Grubbs EG, Perrier ND. Long-term follow-up data may help manage patient and parent expectations for pediatric patients undergoing thyroidectomy. Surgery 152:1165-71, 2012.

Perrier ND. Why I have abandoned robot-assisted transaxillary thyroid surgery. Surgery 152:1025-6, 2012.

Morris LF, Waguespack SG, Edeiken-Monroe BS, Lee JE, Rich TA, Ying AK, Warneke CL, Evans DB, Perrier ND, Grubbs EG. Ultrasonography should not guide the timing of thyroidectomy in pediatric patients diagnosed with multiple endocrine neoplasia syndrome 2A through genetic screening. Ann Surg Oncol 20:53-9, 2013.

Harris R, Ryu H, Vu T, Kim E, Edeiken B, Grubbs EG, Perrier ND. Modern approach to surgical intervention of the thyroid and parathyroid glands. Semin Ultrasound CT MR 33:115-22, 2012.

Landry CS, Grubbs EG, Hernandez M, Hu MI, Hansen MO, Lee JE, Perrier ND. Predictable criteria for selective, rather than routine, calcium supplementation following thyroidectomy. Arch Surg 147:338-44, 2012.

Landry CS, Grubbs EG, Warneke CL, Ormond M, Chua C, Lee JE, Perrier ND. Robot-assisted transaxillary thyroid surgery in the United States: is it comparable to open thyroid lobectomy? Ann Surg Oncol 19:1269-74, 2012.

Williams MD, Zhang L, Elliott DD, Perrier ND, Lozano G, Clayman GL, El-Naggar AK. Differential gene expression profiling of aggressive and nonaggressive follicular carcinomas. Hum Pathol 42:1213-20, 2011.

Landry CS, Grubbs EG, Morris GS, Turner NS, Holsinger FC, Lee JE, Perrier ND. Robot assisted transaxillary surgery (RATS) for the removal of thyroid and parathyroid glands. Surgery 149:549-55, 2011.

Landry CS, Grubbs EG, Busaidy NL, Monroe BJ, Staerkel GA, Perrier ND, Edeiken-Monroe BS. Cystic lymph nodes in the lateral neck as indicators of metastatic papillary thyroid cancer. Endocr Pract 17:240-4, 2011.

Perrier ND, Randolph GW, Inabnet WB, Marple BF, VanHeerden J, Kuppersmith RB. Robotic thyroidectomy: a framework for new technology assessment and safe implementation. Thyroid 20:1327-32, 2010.

Landry CS, Grubbs EG, Perrier ND. Bilateral robotic-assisted transaxillary surgery. Arch Surg 145:717-20, 2010.

Marshall CL, Lee JE, Xing Y, Perrier ND, Edeiken BS, Evans DB, Grubbs EG. Routine pre-operative ultrasonography for papillary thyroid cancer: effects on cervical recurrence. Surgery 146:1063-72, 2009.

Williams MD, Suliburk JW, Staerkel GA, Busaidy NL, Clayman GL, Evans DB, Perrier ND. Clinical significance of distinguishing between follicular lesion and follicular neoplasm in thyroid fine-needle aspiration biopsy. Ann Surg Oncol 16:3146-53, 2009.

Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB. Recent advances in thyroid cancer. Curr Probl Surg 45:156-250, 2008.

Parathyroid Disease

Hunter GJ, Schellingerhout D, Vu TH, Perrier ND, Hamberg LM. Accuracy of four-dimensional CT for the localization of abnormal parathyroid glands in patients with primary hyperparathyroidism. Radiology 264:789-95, 2012.

Morris GS, Landry CL, Grubbs EG, Jimenez C, Busaidy NL, Perrier ND. Greater than age-predicted functional deficits in older patients with primary hyperparathyroidism. Endocr Pract 18:450-5, 2012.

Harris R, Ryu H, Vu T, Kim E, Edeiken B, Grubbs EG, Perrier ND. Modern approach to surgical intervention of the thyroid and parathyroid glands. Semin Ultrasound CT MR 33:115-22, 2012.

Abbott DE, Cantor SB, Grubbs EG, Santora R, Gomez HF, Evans DB, Lee JE, Vu T, Perrier ND. Outcomes and economic analysis of routine preoperative 4-dimensional CT for surgical intervention in de novo primary hyperparathyroidism: does clinical benefit justify the cost? J Am Coll Surg 214:629-37, 2012.

Perrier ND, Evans DB. Population-level predictors of persistent hyperparathyroidism. Surgery 150:1120-1, 2011.

Vu TH, Guha-Thakurta N, Harrell RK, Ahmed S, Kumar AJ, Johnson VE, Perrier ND, Hamberg LM, Hunter GJ, Schellingerhout D. Imaging characteristics of hyperfunctioning parathyroid adenomas using multiphase multidectector computed tomography: a quantitative and qualitative approach. J Comput Assist Tomogr 35:560-7, 2011.

Perrier ND. The parathyroid glands: what the endocrine surgeon should know. Endocr Pract 17 Suppl 1:1, 2011.

Moreno MA, Callender GG, Woodburn K, Edeiken-Monroe BS, Grubbs EG, Evans DB, Lee JE, Perrier ND. Common locations of parathyroid adenomas. Ann Surg Oncol 18:1047-51, 2011.

Landry CS, Ruppe MD, Grubbs EG. Vitamin D receptors and parathyroid glands. Endocr Pract 17 Suppl 1:63-8, 2011.

Silberfein EJ, Bao R, Lopez A, Grubbs EG, Lee JE, Evans DB, Perrier ND. Reoperative parathyroidectomy: location of missed glands based on a contemporary nomenclature system. Arch Surg 145:1065-8, 2010.

Morris GS, Grubbs EG, Hearon CM, Gantela S, Lee JE, Evans DB, Holmes HM, Busaidy NL, Jimenez C, Perrier ND. Parathyroidectomy improves functional capacity in "asymptomatic" older patients with primary hyperparathyroidism: a randomized control trial. Ann Surg 251:832-7, 2010.

Perrier ND, Balachandran D, Wefel JS, Jimenez C, Busaidy N, Morris GS, Dong W, Jackson E, Weaver S, Gantela S, Evans DB, Grubbs EG, Lee JE. Prospective, randomized, controlled trial of parathyroidectomy versus observation in patients with "asymptomatic" primary hyperparathyroidism. Surgery 146:1116-22, 2009.

Benge JF, Perrier ND, Massman PJ, Meyers CA, Kayl AE, Wefel JS. Cognitive and affective sequelae of primary hyperparathyroidism and early response to parathyroidectomy. J Int Neuropsychol Soc 15:1002-11, 2009.

Shin SH, Holmes H, Bao R, Jimenez C, Kee SS, Potylchansky E, Lee JE, Evans DB, Perrier ND. Outpatient minimally invasive parathyroidectomy is safe for elderly patients. J Am Coll Surg 208:1071-6, 2009.

Callender GG, Grubbs EG, Vu T, Hofstetter WL, Fleming JB, Woodburn KL, Lee JE, Evans DB, Perrier ND. The fallen one: the inferior parathyroid gland that descends into the mediastinum. J Am Coll Surg 208:887-93, 2009.

Weaver S, Doherty DB, Jimenez C, Perrier ND. Peer-reviewed, evidence-based analysis of vitamin D and primary hyperparathyroidism. World J Surg 33:2292-302, 2009.

Rizwan MM, Perrier ND. Long-term lithium therapy leading to hyperparathyroidism: a case report. Perspect Psychiatr Care 45:62-5, 2009.

Perrier ND, Edeiken B, Nunez R, Gayed I, Jimenez C, Busaidy N, Potylchansky E, Kee S, Vu T. A novel nomenclature to classify parathyroid adenomas. World J Surg 33:412-6, 2009.

Grubbs EG, Mittendorf EA, Perrier ND, Lee JE. Gamma probe identification of normal parathyroid glands during central neck surgery can facilitate parathyroid preservation. Am J Surg 196:931-5, 2008.

Grubbs EG, Rafeeq S, Jimenez C, Feng L, Lee JE, Evans DB, Perrier ND. Preoperative vitamin D replacement therapy in primary hyperparathyroidism: safe and beneficial? Surgery 144:852-8, 2008.

Monroe DP, Edeiken-Monroe BS, Lee JE, Evans DB, Perrier ND. Impact of preoperative thyroid ultrasonography on the surgical management of primary hyperparathyroidism. Br J Surg 95:957-60, 2008.

Philip M, Guerrero MA, Evans DB, Hunter GJ, Edeiken-Monroe BS, Vu T, Perrier ND. Efficacy of 4D-CT preoperative localization in 2 patients with MEN 2A. J Surg Educ 65:182-5, 2008.

Mortenson MM, Evans DB, Lee JE, Hunter GJ, Shellingerhout D, Vu T, Edeiken BS, Feng L, Perrier ND. Parathyroid exploration in the reoperative neck: improved preoperative localization with 4D-computed tomography. J Am Coll Surg 206:888-95, 2008.

Guerrero MA, Evans DB, Lee JE, Bao R, Bereket A, Gantela S, Griffin GD, Perrier ND. Viability of cryopreserved parathyroid tissue: when is continued storage versus disposal indicated? World J Surg 32:836-9, 2008.

Doherty DB, Mittendorf EA, Valentine AD, Perrier ND. An elderly woman with primary hyperparathyroidism exhibits improvement of neurocognitive dysfunction after parathyroidectomy. J Am Geriatr Soc 55:1689-91, 2007.

Adrenal Tumors

Cooper AB, Habra MA, Grubbs EG, Bednarski BK, Ying AK, Perrier ND, Lee JE, Aloia TA. Does laparoscopic adrenalectomy jeopardize oncologic outcomes for patients with adrenocortical carcinoma? Surg Endosc, Epub 2013.

Dickson PV, Alex GC, Grubbs EG, Jimenez C, Lee JE, Perrier ND. Robotic-assisted retroperitoneoscopic adrenalectomy: making a good procedure even better. Am Surg 79:84-9, 2013.

Grubbs EG, Rich TA, Ng C, Bhosale PR, Jimenez C, Evans DB, Lee JE, Perrier ND. Long-term outcomes of surgical treatment for hereditary pheochromocytoma. J Am Coll Surg 216:280-9, 2013.

Habra MA, Ejaz S, Feng L, Das P, Deniz F, Grubbs EG, Phan A, Waguespack SG, Ayala-Ramirez M, Jimenez C, Perrier ND, Lee JE, Vassilopoulou-Sellin R. A retrospective cohort analysis of the efficacy of adjuvant radiotherapy after primary surgical resection in patients with adrenocortical carcinoma. J Clin Endocrinol Metab 98:192-7, 2013.

Miller JA, Kwon DS, Dkeidek A, Yew M, Hisham Abdullah A, Walz MK, Perrier ND. Safe introduction of a new surgical technique: remote telementoring for posterior retroperitoneoscopic adrenalectomy. ANZ J Surg 82:813-6, 2012.

Plouin PF, Fitzgerald P, Rich T, Ayala-Ramirez M, Perrier ND, Baudin E, Jimenez C. Metastatic pheochromocytoma and paraganglioma: focus on therapeutics. Horm Metab Res 44:390-9, 2012.

Morris LF, Perrier ND. Advances in robotic adrenalectomy. Curr Opin Oncol 24:1-6, 2012.

Zhang HM, Perrier ND, Grubbs EG, Sircar K, Ye ZX, Lee JE, Ng CS. CT features and quantification of the characteristics of adrenocortical carcinomas on unenhanced and contrast-enhanced studies. Clin Radiol 67:38-46, 2012.

Dickson PV, Alex GC, Grubbs EG, Ayala-Ramirez M, Jimenez C, Evans DB, Lee JE, Perrier ND. Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy for pheochromocytoma. Surgery 150:452-8, 2011.

Dickson PV, Jimenez C, Chisholm GB, Kennamer DL, Ng C, Grubbs EG, Evans DB, Lee JE, Perrier ND. Posterior retroperitoneoscopic adrenalectomy: a contemporary American experience. J Am Coll Surg 212:659-65, 2011.
Waguespack SG, Rich T, Grubbs E, Ying AK, Perrier ND, Ayala-Ramirez M, Jimenez C. A current review of the etiology, diagnosis, and treatment of pediatric pheochromocytoma and paraganglioma. J Clin Endocrinol Metab 95:2023-37, 2010.

Ayala-Ramirez M, Callender GG, Kupferman ME, Rich TA, Chuang HH, Trent J, Perrier ND, Goodarzi M, Jimenez C. Paraganglioma syndrome type 1 in a patient with Carney-Stratakis syndrome. Nat Rev Endocrinol 6:110-5, 2010.

Grubbs EG, Callender GG, Xing Y, Perrier ND, Evans DB, Phan AT, Lee JE. Recurrence of adrenal cortical carcinoma following resection: surgery alone can achieve results equal to surgery plus mitotane. Ann Surg Oncol 17:263-70, 2010.

Callender GG, Kennamer DL, Grubbs EG, Lee JE, Evans DB, Perrier ND. Posterior retroperitoneoscopic adrenalectomy. Adv Surg 43:147-57, 2009.

Jimenez C, Cabanillas ME, Santarpia L, Jonasch E, Kyle KL, Lano EA, Matin SF, Nunez RF, Perrier ND, Phan A, Rich TA, Shah B, Williams MD, Waguespack SG. Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. J Clin Endocrinol Metab 94:386-91, 2009.

Perrier ND, Kennamer DL, Bao R, Jimenez C, Grubbs EG, Lee JE, Evans DB. Posterior retroperitoneoscopic adrenalectomy: preferred technique for removal of benign tumors and isolated metastases. Ann Surg 248:666-74, 2008.

Grubbs EG, Lee JE. Walz aldosteronoma. World J Surg 32:854-5, 2008.

Multiple Endocrine Neoplasia

Dickson PV, Rich TA, Xing Y, Cote GJ, Wang H, Perrier ND, Evans DB, Lee JE, Grubbs EG. Achieving eugastrinemia in MEN1 patients: both duodenal inspection and formal lymph node dissection are important. Surgery 150:1143-52, 2011.

Waguespack SG, Rich TA, Perrier ND, Jimenez C, Cote GJ. Management of medullary thyroid carcinoma and MEN2 syndromes in childhood. Nat Rev Endocrinol 7:596-607, 2011.

Jasim S, Ying AK, Waguespack SG, Rich TA, Grubbs EG, Jimenez C, Hu MI, Cote G, Habra MA. Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation. Thyroid 21:189-92, 2011.

Grubbs EG, Waguespack SG, Rich TA, Xing Y, Ying AK, Evans DB, Lee JE, Perrier ND. Do the recent American Thyroid Association (ATA) Guidelines accurately guide the timing of prophylactic thyroidectomy in MEN2A? Surgery 148:1302-9, 2010.

Landry CS, Waguespack SG, Perrier ND. Surgical management of nonmultiple endocrine neoplasia endocrinopathies: state-of-the-art review. Surg Clin North Am 89:1069-89, 2009.

Rich TA, Hu MI, Martin JW, Perrier ND, Waguespack SG. CDC73-Related Disorders. In: Pagon RA, Adam MP, Bird TD, Dolan CR, Fong CT, Stephens K, editors. GeneReviews™ [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2013, 2008.

Callender GG, Rich TA, Perrier ND. Multiple endocrine neoplasia syndromes. Surg Clin North Am 88:863-95, 2008.

Wray CJ, Rich TA, Waguespack SG, Lee JE, Perrier ND, Evans DB. Failure to recognize multiple endocrine neoplasia 2B: more common than we think? Ann Surg Oncol 15:293-301, 2008.

Endocrine Pancreas

Atiq M, Bhutani MS, Bektas M, Lee JE, Gong Y, Tamm EP, Shah CP, Ross WA, Yao J, Raju GS, Wang X, Lee JH. EUS-FNA for pancreatic neuroendocrine tumors: a tertiary cancer center experience. Dig Dis Sci 57:791-800, 2012.

Kouvaraki MA, Solorzano CC, Shapiro SE, Yao JC, Perrier ND, Lee JE, Evans DB.  Surgical treatment of nonfunctioning pancreatic islet cell tumors.  J Surg Oncol 89:170-85, 2005.

Brown RE, Scoggins CR, Tamm EP, Reyes AO, Lee JE.  Intrapancreatic accessory spleen masquerading as pancreatic neuroendocrine tumor.  Surg Rounds 27:310–15, 2004.

General Review

Andreou A, Brouquet A, Bharathy KG, Perrier ND, Abdalla EK, Curley SA, Glanemann M, Seehofer D, Neuhaus P, Vauthey JN, Aloia TA. Liver resection for liver metastases from nondigestive endocrine cancer: extrahepatic disease burden defines outcome. Surgery 151:851-9, 2012.

Landry CS, Grubbs EG, Lee JE, Perrier ND. From scalpel to console: a suggested model for surgical skill acquisition. Bull Am Coll Surg 95:20-4, 2010.

Pettiford J, Erasmus J, Grubbs EG, Perrier ND. Dysphagia lucoria: consideration for the endocrine surgeon. Surgery 147:890-2, 2010.