Neuroimmunology of Cancer-Related Symptoms (NICRS) Laboratory

The overall aim of the studies performed within the Neuroimmunology of Cancer-related Symptoms (NICRS) Laboratory is to increase our understanding of the pathophysiology of cancer therapy-induced neurobehavioral toxicity, including neuropathic pain, depressed mood, cognitive dysfunction and fatigue. We then apply this newly-acquired knowledge to the rational design of novel interventions for alleviating symptom burden in patients with cancer. This is important because neurobehavioral deficits resulting from cancer treatment greatly affect patient comfort and functioning, and may lead to lower doses of therapy, treatment holds, and even treatment termination, thus potentially influencing patient survival.

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