History and Highlights


The Core Lab opened for genomics support on November 20, 2000. The lab has built the first cDNA array containing 2,300 genes in duplicate and two additional arrays: a pathway array (1,500 genes) and an EST array (6,500 ESTs). A set of 20K unigene array became available in early October 2002. The Core Lab has processed more than 1,000 microarray experiments during 2001. In addition, the lab finished a SAGE library containing 20,000 tags with a primary ovarian tissue sample and has established an SNP assay. Tissue microarray service is provided under the directorship of Dr. Gregory N. Fuller, chief of neuropathology and immunohistochemistry.



Dr. Zhang was invited to guest edit a special issue titled "Microarrays in Cancer Research" for the December 2006 issue of Technology in Cancer Research and Treatment.

October 26-29, 2006: The Fourth Chinese Conference on Oncology was held in Tianjin, China. Dr. Zhang gave a presentation at the conference. 

October 5, 2006: George Wang defended his Ph.D. thesis.

Rongcai Jiang, M.D., authored a paper which was highlighted on the cover of the October 2006 issue of Proteomics.

September 29, 2006: Wei Zhang, Ph.D., was invited to present Cancer Systems Biology at The University of Texas Medical Branch at Galveston. Galveston, Texas. 

Sarah Dunlap was appointed as an American Legion Auxiliary Fellow in Cancer Research for the 2006-2007 academic year.

Two incoming graduate students of the Graduate School of Biomedical Sciences (GSBS), Kristen Holmes and Borislava Tsanova, joined the lab for a rotation.

Ellen Taylor and family moved back to Indiana. Ellen worked in our lab for six years, contributed to many projects and co-authored a number of papers.

Ilya Shmulevich, Ph.D., who moved to Institute for Systems Biology in Seattle, was profiled in the magazine The Scientist.

The paper by Jon Trent, M.D., Ph.D., et al., on induction of IGFBP3 by Gleevec in GIST was in press in the journal Cancer.

Dr. Zhang received a grant from the Goldhirsh Foundation to study glioma systems biology.

June 26-30, 2006: Dr. Zhang presented Colon Cancer Genomics at the MD Anderson Physicians Network Second Annual Cancer Symposium at Kauai.

Sarah Dunlap received second prize for the MD Anderson Trainee Recognition Day platform competition.

May 17, 2006: Drs. Wei Zhang and Stanley Hamilton chaired a minisymposium on Cancer Genomics at MD Anderson.

April 2006: Dr. Zhang presented at the fifth annual Symposium on Systems Biology. Seattle, Washington.

April 2006: Sarah Dunlap was selected for a platform presentation at the 2006 AACR symposium, Washington, DC.

Tennis star James Blake visited the Cancer Genomics Core Laboratory. He donated money to support gastrointestinal cancer research.

Dr. Zhang gave a presentation at the World Microarray Congress in Vancouver, Canada.

The second edition of the book "Computational and Statistical Approaches to Genomics," edited by Drs. Wei Zhang and Ilya Shmulevich, was published by Springer.

Matt McDonald and Sarah Dunlap co-authored a paper on Shrew1 gene, featured on the cover of the March 2006 issue of Cancer Biology and Therapy.

February 14, 2006: Sarah Dunlap presented her work at the United States and Canadian Academy of Pathology (USCAP) conference in Atlanta.

Sarah Dunlap won an AACR-AFLAC, Inc., Scholar-in-Training Award to present at the 2006 American Association for Cancer Research (AACR) annual meeting. Only 10% of applicants received the award.

Sarah Dunlap won third prize at the Cancer Biology Retreat.

Jheri Dupart received the Minority Faculty Association (MFA) Scholarship: Jones / Wharton Cancer Research Scholarship, Texas Medical Center.

February 2006: Sarah Dunlap was selected to give a platform presentation at the 2006 USCAP symposium, Atlanta. She received a travel award from GSBS to present at the USCAP meeting.