The research program in the Department of Immunology includes a variety of basic and translational immunology research interests, such as:

  • Cancer immunotherapy and checkpoint blockade
  • T cell tolerance and function
  • Inflammation and tumor immunology
  • Mechanism of innate immune activation and regulation
  • Virology and immunology of HIV and HPV infections
  • Development of vaccines
  • Immune receptor signaling
  • Adaptive cellular therapy
  • Immune cell interactions in tissue and tumor microenvironment
  • … and more!

Moreover, the Department of Immunology is home to the new Immunotherapy Platform, created in 2013 under the direction of Drs. James Allison and Padmanee Sharma.  The Immunotherapy Platform seeks to find reliable biomarkers that can be used to predict patients that are suitable for the different immunotherapies available and to establish a close collaboration with industry to find new reagents (e.g. new checkpoint inhibitors) that may be used as monotherapy or in combination to further improve overall survival of cancer patients.

In addition, the Center for Cancer Immunology Research (CCIR) addresses immunology-based approaches to the treatment of cancer, offering a unique research program where basic and translational immunologists work side-by-side with clinicians to facilitate and accelerate the bench-to-bedside transition of innovative cancer immunotherapies.  The CCIR focuses on five research themes, designed to readily translate key discoveries in basic immunology into clinical applications:

  • Innate immunity and signaling mechanism
  • Immune tolerance and T cell function
  • Inflammation and the tumor immune microenvironment
  • Vaccines
  • Antibody and T cell cancer therapeutics

For more information about the CCIR, please visit the Center’s Website:  Center for Cancer Immunology Research

Recent Events

Students sharing their research at the recent CCIR Poster Session (Feb. 2014)