David H. Koch Center for Applied Research of Genitourinary Cancers

The David H. Koch Center for Applied Research of Genitourinary Cancers will accelerate the clinical application of advances in the understanding of disease through the integration of basic and clinical research at MD Anderson Cancer Center.

Located on the 7th floor of the Clinical Research Building, the Koch Center houses the laboratories of 12 scientists who possess complementary expertise in clinical and laboratory investigation. To develop individualized therapy for patients with genitourinary cancer requires targeting specific pathways, modulating the tumor environment, and stimulating immunity. We utilize sophisticated diagnostics, integrated data management systems, and extensive tissue repositories to accomplish our goals.

Areas of expertise in the Koch Center include:

  • Prostate cancer signaling mechanisms and experimental therapy
  • Human vascular map
  • Tumor progression and metastasis
  • Pathology, including tissue derivatives
  • Protein chemistry and bone microenvironment
  • Intra-vital molecular imaging
  • Bone biology
  • Cancer immunology
  • Genetics of urothelial cancer
  • Gene therapy
  • Urology


Post-Graduate Education Program of the David H. Koch Center

The Post-Graduate Education Program of the David H. Koch Center in the Department of Genitourinary Medical Oncology at MD Anderson offers the opportunity for trainees to work closely with investigators on critical problems in oncology today, with a distinct impact on the future. Our approach expands the traditional individual focus of other educational programs, opening up the spectrum of cancer research and treatment to multiple contributions from an integrated team.

Basic scientists and clinicians work closely together in the Koch Center to provide highly relevant training in the fundamental and translational aspects of genitourinary cancer research. No distinctions are made in the value of basic and translational science, as they are bound together with the clear intent of improving survival of our patients. This “community approach” extends to all trainees, where graduate students and postdoctoral fellows (PhDs, MDs, and MD/PhDs) work side-by-side to advance the fundamental mechanisms by which cancer progresses and translate these advances to patient application.

The foundation of the Post-Graduate Education Program of the Koch Center is a Graduate Programs Initiative grant from The University of Texas System awarded in January 2009. This Initiative was based on a Task Force Report describing the need for new and creative organization and content of graduate programs, more adequate stipends for candidates, a very competitive research environment, and expansion of interdisciplinary and multidisciplinary teaching and research opportunities across the System. Of 18 grant proposals, only 7 were funded, and only one grant was awarded to MD Anderson: Graduate Program in Cancer Metastasis Research: From Bench to Bedside (Gary Gallick, PhD).