Since the discovery of cyclin-dependent kinases (CDKs), a family of proteins vital in the early stages of cell development, scientists have tried to target them to disrupt the division and proliferation of cancer cells. This is especially true in breast cancer due to its reliance on this process for growth.
The first generation of these agents, known as CDK inhibitors, targeted both CDK4 and CDK6. That is why they’re known as CDK4...

In January 2020, Bart Wilson had a colonoscopy after complaining of lower abdominal pain and blood in his stool. Sensing something was wrong...
Tim Leary still remembers the shock he felt after he was diagnosed with two cancers in two years – prostate cancer and pancreatic adenocarcinoma...
If you’ve never had a colonoscopy before, you might have some questions about anesthesia.
Is there more than one option, for instance? If so, how does each work, why might doctors pick one over the other, and what side effects can you expect to experience afterward?
For answers, we consulted anesthesiologist Katherine Hagan, M.D.
How many different types of anesthesia are used for colonoscopies?

Cancer is no stranger to Robyn Heid’s family. Robyn, the youngest of 10 children, lost a brother in 1992 to lymphoma and her father to prostate...
Finding out you have cancer can be hard enough. Telling your family, friends and employer that you have cancer can add another layer of stress...
I was diagnosed with an extremely rare myeloproliferative disorder called Rosai-Dorfman disease in 2014. It’s not fatal, but it does cause...
Scott Brenneman embodies a spirit of endurance in every aspect of his life.
He is a corporate attorney focused on security and risk...
On a Saturday in late February, Hussein Abbas, M.D., Ph.D., celebrated becoming a U.S. citizen. It was nearly two decades in the making and...
Most colonoscopies end with a gastroenterologist saying to come back in 10 years for another colorectal cancer screening, a woozy ride home...