How BTK inhibitors treat mantle cell lymphoma
B cells are an important part of the immune system. One of their jobs is to neutralize the threat from a foreign invader known as a pathogen. They do this by producing an antibody that binds with the antigen on the threatening entity.
When an antigen binds to a receptor on a B cell, the B-cell receptor signaling pathway is activated. Bruton’s tyrosine kinase (BTK) is an enzyme that’s critical to the activation of the B-cell...

Stage IV mantle cell lymphoma survivor: ‘Cancer patients have hope’
It all started in October 2018 during a trip to Mexico. I consumed a fruit that caused me to become ill. Upon my return to the U.S., my doctor...
What to know about mantle cell lymphoma
Mantle cell lymphoma was classified as a separate type of non-Hodgkin lymphoma in 1992. Since then, it’s historically been one of the most...
Mantle cell lymphoma patient benefits from clinical trial despite COVID-19 pandemic
Charles Salazar lives in New Jersey, but considers Houston his “second” home.
For four years, he and his wife, Debbie, have been traveling to Houston regularly so he can receive treatment for mantle cell lymphoma, a rare type of non-Hodgkin lymphoma, at MD Anderson.
“Sure, I could have sought care closer to home, but my wife is a nurse who knows her stuff,” he says. “As soon as I was diagnosed, she started researching where...

Clinical trial makes grandfather two-time lymphoma survivor
Jerry McLeary can recall the exact moment he just knew that his journey with a rare form of non-Hodgkin lymphoma would end happily.
Non-Hodgkin lymphoma survivor finds help, hope
Random nose bleeds and unexplained bruises were Edgar Villalta’s first clues that something was wrong. Then little red dots appeared all over...
Autologous stem cell transplant survivor: What to expect
As a volunteer with CanCare and myCancerConnection, MD Anderson's one-on-one program that connects cancer patients and caregivers with others...
Love, interrupted: How mantle cell lymphoma affected a 30-year reunion
Steve and I dated when we were in our 20s. We always had a great time together, but I was completely surprised when he asked me to marry him...
Bone marrow transplant patient meets his donor
In winter 2001, I had this full feeling in my tummy. Kind of like I feel after eating Thanksgiving dinner. But the bloated feeling wouldn't...