About Us


Select publications:

Paik, JH, Ding, Z, Narurkar, R, Ramkissoon, S, Muller, F, Kamoun, WS, Chae, SS, Zheng, H, Ying, H, Mahoney, J, Hiller, D, Jiang, S, Protopopov, A, Wong, WH, Chin, L, Ligon, KL and DePinho, RA. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell. 2009 Nov 6;5(5):540-53.

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z and others. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 2008 Oct 23;455(7216):1129-33.

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR and others. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 2007 Jan 26;128(2):309-23.

Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I and others. Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers. Nature. 2007 Jun 21;447(7147):966-71.

Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C and others. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science. 2007 Oct 12;318(5848):287-90.

Wong KK, Maser RS, Bachoo RM, Menon J, Carrasco DR, Gu Y, Alt FW, DePinho RA. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates aging. Nature. 2003 Feb 6;421(6923):643-8.

Reviews covering major areas of research in his laboratory:

Artandi, SE and DePinho, RA. (2009). Telomeres and telomerase in cancer. Carcinogenesis.

Furnari, FB, Fenton, T, Bachoo, RM, Mukasa, A, Stommel, JM, Stegh, A, Hahn, WC, Ligon, KL, Louis, DN, Brennan, C, Chin, L, DePinho, RA and Cavenee, WK. (2007). Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21, 2683-2710.

Hezel, AF, Kimmelman, AC, Stanger, BZ, Bardeesy, N and Depinho, RA. (2006). Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev 20, 1218-1249.