Open Trainee Positions
Opportunities are currently available in the following areas:
Postdoctoral Fellow Definition:
An individual holding a recent Ph.D. or equivalent doctorate who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity. Appointees must have recently (within three years) received a Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., and DVM) in an appropriate field.
Postdoctoral Appointment Term Limits:
MD Anderson postdoctoral appointment policy limits an individual to no more than five years in the postdoctoral title at MD Anderson, or a total of six years in postdoctoral appointments at any combination of institutions.
Stipend Policy:
Stipend support will follow the NIH NRSA level for the appropriate PGY.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.
View Open Positions
MD Anderson offers postdoctoral training opportunities year-round. Below are the positions currently available.
Anesthesiology & Perioperative Medicine
Req #: 600658-202108171025
Job Title: Postdoctoral Fellow
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This position is for a postdoctoral fellow with interest in the theme of cancer neuroscience. The goal of the program is to understand the interaction between chemotherapies-related toxicities and surgery/anesthesia. Specifically, we are interested in studying how demyelination caused by chemotherapy affects cognitive dysfunction after surgery. To study this intersection, we will use a mice model of chemobrain and postoperative behavioral deficit.
Learning Objectives:
- To develop a mice model to understand the impact of anesthetics on chemobrain
- To develop a mice model to understand the impact of surgery on chemobrain
- To learn behavioral tests to understand chemobrain in mice
- To learn laboratory techniques to understand mechanisms related to chemobrain in mice
Eligibility Requirements:
MD anesthesiologists or PhD with background in neuroscience
Program Dates:
12/01/2021
Mentor Matching:
This position reports to Juan Cata, M.D. View Dr. Cata's research profile.
Req #: 600658-202110031117
Job Title: Postdoctoral Fellow
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The major research focus of the Department of Anesthesiology and Perioperative Medicine (DAPM) is to understand the impact of anesthetics interventions on oncological outcomes. Outcomes research is a brain of public health research. The DAPM has a long history of conducting outcomes research in perioperative oncology. This training position is open to anesthesiologists interested in learning skills in clinical research in the Department of Anesthesiology and Perioperative Medicine. This program is open to both U.S. and international applicants.
Learning Objectives:
The applicant will learn participate and learn about the design of clinical trials that may impact short and long-term cancer outcomes after surgey. The applicant will also learn about rigourous methods, protocol preparation, patient monitoring plan and ethical and legal issues related to clinical research. The applicant will also be connected with national and international experts to learn best practices and develop new solutions to manage clinical research enterprise.
Eligibility Requirements:
M.D. with previous completed residency in anesthesiology in the US or internationally.
Program Dates:
1/1/2022-12/31/2023
Mentor Matching:
This position reports to Juan Cata, M.D. View Dr. Cata's research profile.
Req #: 600658-202112151518
Job Title: Postdoctoral Fellow
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Dr. Cata lab is looking in candidates interested in learning, coordinating and conducting clinical research in the Department of Anesthesiology and Perioperative Medicine. Dr. Cata lab has more more than a dozen of clinical trials in which successful candidate will have the opportunity to collaborate with members of his team and anesthesiologists of the department.
Learning Objectives:
The candidate will:
1- Learn about clinical trial design in anesthesiology and perioperative medicine
2- Learn about basic and advanced statistical methods including adaptive trials
3- Learn about the application of augmented reality in anesthesiology and perioperative medicine.
Eligibility Requirements:
M.D. with previous completed residency in anesthesiology in the U.S. or internationally.
Mentor Matching:
This position reports to Juan Cata, M.D. View Dr. Cata's research profile.
Req #: 600658-202112151515
Job Title: Postdoctoral Fellow
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A postdoctoral position is available in the laboratory of Dr. Juan Cata. The new postdoctoral fellow will investigate the role of the mu-opioid receptor for therapeutic applications in cancer. Head and neck cancers will be the target and emphasis of this work. These studies will employ in vitro and in vivo imaging techniques, cell culture systems, and animal models. The candidate will also collaborate with neuroscientists to investigate how the mu-opioid receptor impacts perineural invasion.
Learning Objectives:
The successful candidate will learn:
1- New laboratory techniques including small extracellular molecule isolation, CRISPR, single-cell sequencing, and basic electrophysiology techniques.
2- Analytical methods to interpret how the mu-opioid receptor affects exosome cargo.
Eligibility Requirements:
Ph.D. with appropriate and current knowledge on cancer biology techniques/protocols. The candidate should have scientific writing skills and have a basic understanding of the following software R, Prizm, excel, and genomic databases.
Mentor Matching:
This position reports to Juan Cata, M.D. View Dr. Cata's research profile.
Applied Cancer Science
Req #: 600140-202112030920
Job Title: Postdoctoral Fellow
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The postdoctoral fellow will be embedded within the Structural Chemistry group in the Institute for Applied Cancer Science, part of the Therapeutics Discovery Division. The position is designed to provide the experience needed to operate as a key member of a drug discovery project team at the program's conclusion. The fellow will perform and analyze calculations, and attend and present results at project team meetings.
Learning Objectives:
The postdoctoral fellow will learn how to a) provide computational chemistry support to drug discovery project teams, b) design novel molecules using structure and ligand-based techniques, c) interface with structural biologists and medicinal chemists, d) communicate insights from molecular modeling to a diverse team of scientists, and e) perform independent computational research aimed at improvinQ desiQn of novel molecules.
Eligibility Requirements:
Ph.D. in Chemistry, Physics, Biology, Biophysics, Theoretical/Computational Chemistry, Chemical Engineering, or a related discipline.
Program Dates:
1 year, with extension to 3 years possible.
Mentor Matching:
This position reports to Jason Cross, Ph.D.
Behavioral Science
No positions in the Department of Behavioral Science are currently available. Check back later for new opportunities.
Bioinformatics and Computational Biology
Req #: 600815-202107181110
Job Title: Postdoctoral Fellow
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Postdoctoral positions are available in Dr. Yiwen Chen's lab. By combining computational and high-throughput approaches such as single-cell multi-omics profiling (e.g., scRNA-seq and scATAC-seq), CRISPR/Cas9, RNA-seq, ChIP-seq, RNA immunoprecipitation (RIP)-seq and Ribosome Profiling (Ribo-seq), the focuses of Dr. Chen's lab are to decipher the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation mechanism of cancer immunology, neural stem cell and cancer stem cell of brain tumor at the University of Texas MD Anderson Cancer Center. The postdocs will be jointly supervised by Dr. Chen and Drs. Jian Hu/Cassian Yee.
Computational Biology/Bioinformatics Postdoc:
The postdoc will be developing novel statistical/machine learning (e.g., deep learning) methods that integrate heterogeneous bulk and single-cell multi-omics datasets to study the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation mechanism that is important for tumor immunity, neural stem cell and cancer stem cell of brain tumor. Another direction is to develop new computational methods for proteogenomics, an emerging field at the intersection of genomics and mass spectrometry (MS)-based proteomics. In addition to the development of statistical/machine learning methods, he/she will be collaborating with other labs for various biomedical applications.
Eligibility Requirements:
Experimental Postdocs:
Applicants should have a Ph.D. degree (or equivalent) in biomedical sciences, focusing on one of the following areas: (a) molecular biology (b) biochemistry of RNA and/or transcriptional/epigenetic regulation, (c) cell signaling, (d) virology, (e) immunology, (f) T-cell biology, (g) cancer biology. Mouse model experience, genomics/proteomics expertise is not required, but highly desirable.
Computational Biology/Bioinformatics Postdocs
Applicants should have a Ph.D. degree (or equivalent) in related quantitative fields including, but not limited to computational biology, bioinformatics, biophysics, biostatistics, computer science, statistics, bioengineering and physics. Applicants with i) strong quantitative background (computer science/statistics/physical modeling) or ii) computational genomics/proteomics experiences and large-scale biological data analysis capability are preferred. Strong programming skills in scripting language (Python or Perl), statistical and computing language (R or MATLAB), and/or programing language (C/C++ /Java) are highly desirable.
Dates or Training Schedule:
January 2021 – January 2022, renewed annually.
Mentor Matching:
This position reports to Yiwen Chen, Ph.D., and Cassian Yee, M.D.
Req #: 600815-202107181130
Job Title: Postdoctoral Fellow
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The University of Texas MD Anderson Cancer Center invites applications for a postdoctoral position in bioinformatics and computational biology. The position is sponsored by Dr. Han Liang lab in the Department of Bioinformatics and Computational Biology. The Liang lab combines computational and experimetnal approaches to realize the full promise of precsion cancer medicine. The projects will focus on the genomic data analysis for understanding the evolutionary process and treatment response of human cancer and the development of related bioinformatics tools.
Eligibility Requirements:
The ideal candidate should have a PhD. in bioinformatics, quantitative sciences, biology and related areas; have strong skills in bioinformatics, statistical knowledge, and programming skills; have first-hand experience in next-generation sequencing data analysis and genomic data mining; and have a publication record that demonstrates the above expertise. Knowledge about cancer biology would be a plus. We are looking for an outstanding researcher with high motivation, ability to work collaboratively and independently, and a strong commitment to working on the projects.
Program Dates:
8/1/2021-7/31/2024
Mentor Matching:
This position reports to Han Liang, Ph.D. See Dr. Liang's research profile.
Additional Application Information:
MD Anderson is ranked one of the top two hospitals for cancer care and research in the nation for 25 years in a row by U.S. News & World Report. The lab website is http://odin.mdacc.tmc.edu/~hliang1.
Please send a (1) cover letter that describes your past research and future goals, (2) curriculum vitae, and (3) the names of three references that includes your connection to the references, to:
Han Liang, Ph.D.
Professor and Deputy Chair,
Department of Bioinformatics & Computational Biology
MD Anderson
Houston, TX 77030
Req #: 600815-202107260642
Job Title: Postdoctoral Fellow
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We are seeking outstanding applicants for postdoctoral positions to work at the intersection of cancer immunology, adoptive cell therapy, single-cell omics and artificial intelligence under the supervision of Dr. Ken Chen in the Department of Bioinformatics and Computational Biology.
Dr. Ken Chen had over 15-year professional experience in computational cancer biology in the context of cutting-edge cancer research. His lab focuses on characterizing the genomic, transcriptomic and proteomic profiles of patient's tumor samples and match with evidence-based targeted- and immuno- therapies (Personalized therapy of Cancer) for better outcomes. New high-throughput technologies such as single-cell sequencing and mass cytometry are often utilized to dissect novel cell types and identify underlying molecular mechanisms that are involved in pathogenesis. The lab has been well funded by NIH, the Cancer Prevention and Research Institute of Texas, Chan-Zuckerberg Initiative, Andy Sabin Foundations, and MD Anderson Moonshots with lots of collaborative opportunities in the area of immunotherapy and targeted therapy. Former trainees in the lab have routinely published first-author papers in top computational biology journals such as Nature Methods and have secured leadership positions in either academia or industry.
Learning Objectives:
- Towards research independence in computational biology
- Learn to develop computational algorithms/models to generate or test biological hypotheses
- Learn to analyze data in biologically meaningful ways
- Learn team science
Eligibility Requirements:
We are recruiting creative, enthusiastic recent PhD graduates, who would like to develop a professional career in biomedical/cancer research and have:
- Ph.D. in Bioinformatics/Biostats, Math/Statistics/Physics, Computer Science/Engineering
- Experience analyzing and interpreting high-throughput data such as DNA and RNA sequencing, microarray, and mass cytometry data
- Experience developing and disseminating novel computational tools
- Proficient in programming languages such as Python, R, Java, Matlab, C/C++
- At least 2 first-author publications in peer reviewed journals.
Mentor Matching:
This position reports to Ken Chen, Ph.D. See Dr. Chen's research profile.
Req #: 600815-202109091707
Job Title: Postdoctoral Fellow
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One postdoctoral position in systems biology is available in the Hart Lab (hart-lab.org) at The University of Texas MD Anderson Cancer Center in Houston, TX. CRISPR has revolutionized human functional genomics by rendering our genome tractable, and the Hart Lab is pushing the state of the art in the design, assay, and integrated analysis of CRISPR tools for complex genetics. We are developing multiplex perturbation technologies with a wide variety of applications from basic functional genomics to finding novel chemotherapeutic targets and understanding how tumor cells adapt to targeted therapies. Because of this breadth, we maintain strong collaborations throughout MD Anderson, the Texas Medical Center, nationally, and internationally.
We are seeking a self-motivated candidate from looking to take the next step in his or her career at a world-class research institution. If you have a background or strong interest in quantitative systems biology, a compulsion to understand complex data, a desire to work in a hybrid wet/dry environment, and a drive to make your mark in one of the most exciting frontiers in biomedical research today, apply today! The Hart Lab offers a supportive and diverse team environment, and the chance to live and work in the fourth largest city in the nation. Interested candidates are encouraged to send a CV and a statement of research interests.
Eligibility Requirements:
PhD in Cell/Molecular Biology, Biochemistry, or equivalent. Extensive experience with cloning and mammalian cell culture is required; additional expertise with lentivirus, flow cytometry/CyTOF, and quantitative sequencing preferred.
Mentor Matching:
This position reports to Traver Hart, Ph.D. See Dr. Hart's research profile.
Req #: 600815-202110041945
Job Title: Postdoctoral Fellow
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A bioinformatics/computational biology postdoctoral fellow will work in the development and application of machine learning and informatics algorithms in computational precision oncology. The projects involve analysis of multi-omics data from cancer patients to discover of theraputic vulnaribilities in cancer patients. The multi-omic data involves DNA, RNA and proteomics profiles including spatially resolved single cell data that is generated for variaus cancer types (colorectal, rare tumors, pancreatic cancers, GBM) in our laboratory.
Learning Objectives:
1. Learning machine learning and informatics algorithms for analysis of spatially resolved single cell proteomics data from cancer patients.
2. Learning informatics and machine learning applications for development of precision combination therapies.
3. Learning how to generate of software tools for effective mining of large omics datasets from cancer patients.
Eligibility Requirements:
PhD (or equivalent) in relavant areas including but not limited to bioinformatics, computational biology, systems biology, physics, biophysics
Advanced knowledge of machine learning, bioinformatics and quantitative methods in biology.
An understanding of cancer biology.
Mentor Matching:
This position reports to Anil Korkut, Ph.D. See Dr. Korkut's research profile.
Req #: 600815-202110041951
Job Title: Postdoctoral Fellow
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A bioinformatics/computational biology postdoctoral fellow will work in development and application of machine learning and informatics algorithms for analysis of multi-omics data from cancer patients. The multi-omic data involves DNA, RNA and proteomics datasets including spatially resolved single cell data that is generated for variaus cancer types (colorectal, rare tumors, pancreatic cancers, GBM) in our laboratory.
The fellow will generate original algorithms and software for extracting combination therapuy vulnaribilities from diverse datasets that will be translated to clinical applications in collaborations with our collaborators.
Learning Objectives:
1. Learining informatics algorithms for analysis of spatially resolved single cell proteomics data from cancer patients.
2. Learning informatics applications for development of precision combination therapies.
3. Learning how to generate of software tools for effective mining of large omics datasets from cancer patients.
Eligibility Requirements:
PhD (or equivalent) in relavant areas including but not limited to bioinformatics, computational biology, systems biology, physics, biophysics
Advanced knowledge of machine learning, bioinformatics and quantitative methods in biology.
A basic understanding of basic cancer biology.
Mentor Matching:
This position reports to Anil Korkut, Ph.D. See Dr. Korkut's research profile.
Req #: 600815-202110271806
Job Title: Postdoctoral Fellow
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A full-time postdoctoral fellow position is available in Dr. Wenyi Wang's lab, at the Department of Bioinformatics and Computational Biology at the University of Texas MD Anderson Cancer Center. Dr. Wang's laboratory performs research aiming to gain new knowledge in the evolution of the human genome as well as the cancer genome. These two topics are fundamental to the understanding of the initiation, progression and treatment of human diseases. Currently her laboratory is focused on two research directions:
1) Development of integrative deconvolution and single-cell models in order to build an atlas of gene expression states of tumor and immune cells (tumor microenvironment) during cancer evolution; and
2) Statistical models for cancer risk counseling for individuals with deleterious germline mutations. For further information, visit the lab website.
The postdoctoral fellow position is a full-time, 12-month . The selected candidate will join the research programs in tumor heterogeneity and evolution, human cell atlas network, or personalized risk prediction modeling for clinical dissemination.
The proposed start date is on a rolling basis. The postdoctoral fellow will be mentored directly by Dr. Wang, with possible co-mentorship from qualified MD Anderson faculty members, including Physician Scientists, or from other institutions in the Texas Medical Center, including Rice University. Applications will be accepted until the position is filled.
Learning Objectives:
1. Learn to develop independent research programs and successfully participate in team science
2. Learn to apply statistics, informatics and machine learning to develop novel methods for analysis of large omics datasets
3. Learn to develop statistical models and computational algorithms for generating and/or testing biological hypotheses that possess clinical utility
4. Learn to interpret and analyze biological data
Eligibility Requirements:
A Ph.D. degree in statistics, biostatistics, applied mathematics, bioinformatics, computer science or a related field. Extensive experience with R and Python, prior experience in computational biology are required. Candidates with a background in any of the following areas are preferred: cancer biology, graphical models, semi-parametric Bayesian models, or penalized likelihood methods.
To apply, send a curriculum vitae, a research statement and three references titled "Postdoctoral application - Name" to wwang7@mdanderson.org.
Mentor Matching:
This position reports to Wenyi Wang, Ph.D. See Dr. Wang's research profile.
Req #: 600815-202201191810
Job Title: Postdoctoral Fellow
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A Postdoctoral Fellow position in the field of experimental metabolomics is available at The University of Texas MD Anderson Cancer Center Metabolomics Core Facility. We seek a highly motivated individual with a PhD degree in chemistry, biochemistry, or related fields. Experience with liquid chromatography-mass spectrometry (LC-MS)-based metabolomics is required. Experience with both metabolomics and proteomics is preferred. Salary commensurate with experience. The finalist will gain valuable experience in the development of bioanalytical methods for quantitative metabolomics and lipidomics and contribution to cancer research. The laboratory environment is highly collaborative with projects in cancer biology, metabolomics, proteomics, drug development, systems biology, systems pharmacology, bioinformatics, cellular biology, and molecular biology distributed across the spectrum of basic, preclinical, and clinical research.
Learning Objectives:
The laboratory environment is highly collaborative with projects in cancer biology, metabolomics, proteomics, drug development, systems biology, systems pharmacology, bioinformatics, cellular biology, and molecular biology distributed across the spectrum of basic, preclinical, and clinical research. The finalist will conduct lipidomic profiling of the NCI-60 cell line panel to facilitate discovery of novel associations between lipid levels and drug response or mutation status. The finalist will also learn to analyze the resulting data to elucidate a housekeeping lipid for the normalization of metabolomic and lipidomic data. Interested candidates should submit their curriculum vitae by email.
Eligibility Requirements:
Applicants must have completed their PhD within 3 years of application for this position.
Program Dates:
March 1, 2022 - February 28, 2023
Mentor Matching:
This position reports to Philip Lorenzi, Ph.D.
Biostatistics
Req #: 600567- 202110081607
Job Title: Postdoctoral Fellow
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The Postdoctoral Fellow will work under the joint supervision of Peter F. Thall, Ph.D., and Ruitao Lin, Ph.D. The research will encompass an array of different possible projects, with primary focus on: (1) developing novel statistical methodologies and computer software for Bayesian adaptive designs for precision medicine, (2) investigating Bayesian learning approaches, such as Bayesian nonparametrics, BART, etc., with applications to clinical trials that may include multiple patient biological or prognostic subgroups, or disease subtypes. The Fellow will actively participate in research meetings with medical collaborators to implement applications related to methodological research projects. Other activities may include analyses of datasets having complex structures, potentially leading to methodological research.
Learning Objectives:
Learn statistical methodology and application for oncology clinical trials, Bayesian non- and semi-parametric modeling, advanced statistical learning techniques, and high dimensional or survival analyses. Develop novel Bayesian methods for precision medicine, develop strong programming and computational skills. Adapt and develop novel machine learning algorithms; Acquire extensive experience in R, R-Shiny, Python, and other programming languages/environments.
Eligibility Requirements:
We seek a highly motivated individual with a Ph.D. in statistics, biostatistics, or a related quantitative field. Candidates must have strong methodological training in statistics or biostatistics, and strong computer programming skills, in particular R/Matlab and at least one lower level computer language, such as C++. Expertise or skills in the following areas are highly desirable: Bayesian MCMC computational methods, adaptive clinical trial design, optimization, numerical analysis, machine learning, causal inference.
Please send CV and information on three referees directly to slgarcia@mdanderson.org.
MD Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.
Dates or Training Schedule:
Tentative Start Date: December 2021
Mentor Matching:
Dr. Ruitao Lin and Dr. Peter Thall are professors in the Department of Biostatistics with prior mentoring experience.
Additional Application Information:
The mission of The University of Texas MD Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.
Req #: 600567- 202110130924
Job Title: Postdoctoral Fellow
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The Postdoctoral Fellow will work under the joint supervision of Ying Yuan, Ph.D. and Ruitao Lin, Ph.D. The research will encompass an array of different possible projects, with primary focus on: (1) developing novel statistical methodologies and computer software for Bayesian adaptive clinical trial designs, including the use of real-world data or evidence in clinical trial designs. (2) investigating Bayesian learning approaches such as Bayesian nonparametrics, BART, etc., with an application to clinical trials, including identification of optimal treatment regimens or adaptive decision making for prediction medicine. The Fellow will actively participate in research meetings with medical collaborators to implement applications related to methodological research projects. Other activities also may include analyses of datasets having complex structures, potentially leading to methodological research.
Learning Objectives:
Learn statistical methodology and application for oncology clinical trials, Bayesian non- and semi-parametric modeling, advanced statistical learning techniques, and high dimensional or survival analyses. Develop novel Bayesian methods for precision medicine, develop strong programming and computational skills. Adapt and develop novel machine learning algorithms; Acquire extensive experience in R, R-Shiny, Python, and other programming languages/environments.
Eligibility Requirements:
We seek a highly motivated individual with a Ph.D. in statistics, biostatistics, or a related quantitative field. Candidates must have strong methodological training in statistics or biostatistics, and strong computer programming skills, in particular R/Matlab and at least one lower level computer language, such as C++. Expertise or skills in the following areas are highly desirable: Bayesian MCMC computational methods, adaptive clinical trial design, optimization, numerical analysis, machine learning, causal inference.
Please send CV and information on three referees directly to slgarcia@mdanderson.org.
Dates or Training Schedule:
Tentative Start Date: December 2021
Mentor Matching:
Dr. Ruitao Lin and Dr. Ying Yuan are professors in the Department of Biostatistics with prior mentoring experience.
Req #: 600567-202201191609
Job Title: Postdoctoral Fellow
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The postdoctoral fellow will work under the supervision of Kim-Anh Do, Ph.D. and Ziyi Li, Ph.D. and may collaborate with other faculty in biostatistics, computer science, bioinformatics, basic science, or clinical research. The primary research focus can encompass: (i) developing and applying novel statistical and computational methods for the analysis of omics data from various sources such as high-throughput proteomic, genomic, sequencing, transcriptomic, and imaging data, with particular emphasis on developing integrative and flexible models that incorporate both biological knowledge and empirical structures; (ii) developing novel statistical and machine learning methods for the analysis of single cell omics data with focuses on cancer research. Specific research areas include the integration of single cell and bulk data, the incorporation of cell interaction and spatial information in single cell data analysis, and the analysis of single cell multi-omics data. The fellow will gain experience in cutting-edge analysis of “big data” and have the opportunity to publish in high-impact biostatistics, bioinformatics and health research journals.
Learning Objectives:
Learn statistical theory and application in data science studies; Obtain expertise in high-dimensional variable selection, feature extraction from spatial-temporal varying data, hierarchical models, develop novel analytical methods for precision medicine; Develop strong programming and computational skills; Adapt and develop novel machine learning algorithms; Acquire extensive experience in R, R-Shiny, Python, and other programming languages/environments.
Eligibility Requirements:
We seek a highly motivated individual with a Ph.D. in statistics/biostatistics/bioinformatics or a related quantitative field such as computer science, engineering, or quantitative computational biology. Interest or background in computer-intensive methodology, bioinformatics, genomics, and proteomics is preferred. Applicants must have strong training in statistics and excellent programming skills, in particular R/Python/Matlab and preferably one lower level computer language such as C or Fortran, and interest in the application of state-of-the-art statistical methods to complex data. Experience with high-performance computing and linux system is a plus. Expertise or skills in any of the following areas are desirable: analysis of high-dimensional data, data mining, and machine learning.
Interested applicants should send a cover letter and CV (including three references) to: kimdo@mdanderson.org and zli16@mdanderson.org (subject line: Do-Li-postdoc-2022).
MD Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.
Dates or Training Schedule:
Tentative Start Date: September 2022
Mentor Matching:
Dr. Kim-Anh Do and Dr. Ziyi Li are faculties in the Department of Biostatistics with prior mentoring experience.
Breast Medical Oncology
Req #: 600143-202108271607
Job Title: Postdoctoral Fellow
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My lab is conducting basic and translational breast cancer research to understand the aggressiveness of breast cancers by studying oncogenic signaling pathways, cancer stem cells, and the impact of the microenvironment (inflammation and immunological effect). Over the past 15 years, my lab has developed research projects in EGFR, MAPK, JNK, and TIG1 to target triple-negative breast cancer, inflammatory breast cancer, metastasis, and cancer stem cells. Recently, my research is extended to the tumor immune microenvironment.
My research goal is developing molecular therapeutics for breast cancer by hypothesis-driven translational research and contributing to the successful completion of clinical research, thereby reducing breast cancer mortality. Our lab is interested in generating next generation of leaders in breast cancer research through research, mentorship, and leadership training.
We seek highly motivated post-doctoral research fellows with strong research capabilities. Prior experience in cancer biology and immunology is highly desirable. In addition, the candidate must be self-driven, ethical, and a team player.
Eligibility Requirements:
Education: PhD, PhD/MD
Experience : required basic molecular biology, cancer biology, immunology techniques, and mouse xenograft models.
Mentor Matching:
This position reports to Naoto Ueno, M.D., Ph.D. View Dr. Ueno's research profile.
Additional Application Information:
The fellow will need to provide their own stipend support from their home institution. Under no circumstances should a postdoctoral fellow's or other individual's personal funds be used to supplement an internally or externally supported stipend to the MD Anderson minimum level.
Req #: 600143-202110050901
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Department of Breast Medical Oncology. The laboratory conducts basic and translational research to understand the aggressiveness of inflammatory breast cancer (IBC) and establish effective targeted therapies for patients with IBC. The research focuses on the mechanism underlying tumorigenesis and metastasis of IBC and the modulation of tumor microenvironment. Technologies include humanized/transgenic mouse modeling, immune profiling, single-cell RNA sequencing, multiplexed immunofluorescence staining, and in vitro and in vivo drug screening. The postdoctoral fellow will have the opportunity to work with clinical collaborators to learn how to translate the bench work into clinical trials. The postdoctoral fellow will also have the opportunity to work with the pharmaceutical companies to accelerate the translation of promising therapeutic drugs.
Eligibility Requirements:
Applicants must have a recent Ph.D. degree with experience in molecular biology, cell biology, cancer biology, or related fields. We seek a highly motivated and self-driven post-doctoral research fellow with strong research capabilities. We expect the postdoc candidate to join the lab in six months.
Mentor Matching:
This position reports to Xiaoping Wang, Ph.D. View Dr. Wang's research profile.
Cancer Biology
Req #: 188100-202107181120
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Department of Cancer Biology under the direct supervision of Dr. Shabnam Shalapour. Research in the Shalapour Laboratory focuses on the role of chronic inflammation and adaptive immunity in control of tumor development and the response of various cancers to therapy. While the focus of the research is primarily based on tumor immunology and immunotherapy, our work also addresses fundamental questions in immunology, immunometabolism and cancer biology using cutting-edge technology tools including multicolor Flow cytometry, CyTOF, imaging, histology and large-scale omic analysis, e.g. single-cell RNA and ATAC-seq . We aim to understand how chronic inflammation induced by obesity, aging and alcohol abuse affect the immune system and thereby regulates its response to pathogens (bacteria and virus) and support tumor development. The focus then being how to use this information to not only prevent cancer development but also to develop novel therapeutic approaches to increase the response to immunotherapy and vaccination (see our recent publications; Nature. 2015 May 7;521(7550):94-8, J Clin Invest. 2015 Sep;125(9), Nature. 2017 Nov 16;551(7680):340-345.; Immunity. 2019 Jul 16;51(1):15-26, Annu Rev Immunol. 2020 Apr 26;38:649-671).
Learning Objectives:
This postdoc fellowship will focus on the role of adaptive immune cells particular B cells in tumor immunology, and how chronic-inflammation regulate their development and effector function, using bioinformatic tools, genetically engineered mouse models (GEMM) and state-of-the-art immunological and experimental approaches.
Eligibility Requirements:
Applicants must have a recent Ph.D. or M.D./Ph.D. degree in a related biomedical field with strong interests and self-motivation for research.
Dates or Training Schedule:
The appointment is immediately available.
Mentor Matching:
This position reports to Dr. Shabnam Shalapour.
Req #: 188100-202107181130
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Department of Cancer Biology under the direct supervision of Dr. Raghu Kalluri. The central mission of the Kalluri Laboratory is to perform innovative and cutting-edge research to unravel how cells and their environment communicate to maintain organ health and how such communication network in tissues is altered in cancer and other diseases. We investigate the biology of cancer with an implicit mission to develop new strategies for diagnosis and therapy.
Learning Objectives:
This postdoctoral fellowship will focus on pancreatic cancer.
Eligibility Requirements:
Applicants must have a recent Ph.D. degree with strong research interests.
Dates or Training Schedule:
The appointment is immediately available.
Mentor Matching:
This position reports to Raghu Kalluri, M.D., Ph.D..
Req #: 188100-202107181140
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Department of Cancer Biology under the direct supervision of Dr. DePinho. Our research focus on studying the molecular and biological processes governing the development of cancer, the basis for aging and degenerative diseases and the maintenance of normal and cancer stem cells. We have produced an array of discoveries leading to better methods of early cancer detection, improved cancer patient care and new cancer drug development. The range of our research includes cancer drug and biomarker development, cancer gene discovery, stem cell biology and development of genetically engineered mouse models to study human cancers.
All trainees are provided with consistent mentorship and access to a number of resources to ensure success. Trainees will have opportunities to present their work at national meetings and attend educational seminars. In addition, collaboration and contribution on other projects in the lab are encouraged.
Learning Objectives:
Qualified individuals will demonstrate the potential for research as evidenced by their peer-reviewed publications and funding. He/she will have background in cancer biology and expertise in the design experiments and execution of in vitro and in vivo experiments. Have expertise in molecular biology, cell culture, animal work etc.
Eligibility Requirements:
Applicants must have a recent Ph.D. degree with strong research interests.
Dates or Training Schedule:
The appointment will begin in March 2021.
Mentor Matching:
This position reports to Ronald DePinho, M.D.
Req #: 188100-202107181150
Job Title: Postdoctoral Fellow
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The Kalluri laboratory at the MD Anderson Cancer Center wants to expand their work on the molecular underpinnings of cancer initiation, progression and metastasis, and to translate the findings into novel therapeutic approaches. The Kalluri laboratory focuses on innovation research in the area of cancer biology with a specific focus on oncogene addiction, tumor microenvironment, stromal biology, exosomes biology, tumor metabolism and tumor immunology. Recent publications on the stromal biology of cancer (Ozdermir et al. 2014, Cancer Cell), exosomes biology in cancer (Kalluri & LeBleu, 2020, Science, Melo et al., 2014 Cancer Cell; Melo et al. 2015, Nature), tumor immunology (Ozdermir et al. 2014, Cancer Cell; Carstens et al. 2017, Nature Communications), metastasis (Zheng et al. 2015, Nature; Lovisa et al. 2015, Nature Medicine), exosomes mediated oncogene targeting (Kamerkar et al. 2017, Nature) and tumor metabolism (LeBleu et al. 2014, Nature Cell Biology, Becker et al. 2020, Cell Reports), have formed the framework for the next set of projects that use innovative technologies such as CRISPR-Cas9, single cell and nuclei sequencing, exosome engineering and mouse modeling to address cutting-edge questions in cancer biology. The Kalluri laboratory strives to transform seminal basic cancer research to inform clinical translation of such findings and will employ any required technology to address important unanswered questions in cancer biology. With strong funding from the NCI, CPRIT Established Investigator Award, and other funding sources, the laboratory is well positioned to exploit the new avenues for fundamental discoveries in cancer and translate such findings into the clinic, exploiting the translational potential of MD Anderson Cancer Center.
Learning Objectives:
We seek outstanding candidates with a strong background in neurobiology. Expertise may include a focus on neurodegenerative diseases, synapse biology, neuroimaging, brain and peripheral neuropathies, and brain tumor. We are only interested in scientists who are committed to solve important questions in neurobiology and are innovative and `out of the box' in their approach of science. The candidate must demonstrate expertise in neurobiology, and interests in exosomes biology, tumor biology, mouse modeling of disease (with a focus on neurodegenerative disorders), and in advancing therapeutic testing. The ideal candidate must demonstrate a committed enthusiasm for science, superior interpersonal and communication skills, exceptional organization skills, and is able to work in dynamic teams.
Eligibility Requirements:
Applicants must have a recent Ph.D. degree with strong research interests.
Dates or Training Schedule:
The appointment is immediately available.
Mentor Matching:
This position reports to Raghu Kalluri, M.D., Ph.D..
Additional Application Information:
To apply, a cover letter is required, and should indicate areas of research interest, highlight publication record, and list future professional aspirations. Candidates must also submit a complete CV, key publications if any, and a minimum of 3 reference letters via E-mail to:
Jennifer Yang
Department of Cancer Biology
1881 East Road, Box 1906
UT MD Anderson Cancer Center
jsyang@MDAnderson.org
Req #: 188100-202111101351
Job Title: Postdoctoral Fellow
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Functional Genomics at the Department of Cancer Biology, under the direct supervision of Dr. Yejing Ge. We are seeking talented and passionate individuals to join our team. We apply principles of developmental biology, exploiting mouse genetics and functional genomic approaches to tackle fundamental questions in cancer biology.
Learning Objectives:
The overarching goal of our research program is to understand basic molecular mechanisms underlying stem cell plasticity, and how its deregulation causes human diseases, including wounds, cancer and aging.
Eligibility Requirements:
Applicants must have a recent Ph.D. degree with strong research interests.
Dates or Training Schedule:
The appointment is immediately available.
Mentor Matching:
This position reports to Yejing Ge, Ph.D.
Cancer Systems Imaging
Req #: 710509-202108131545
Job Title: Postdoctoral Fellow
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The department of Cancer Systems Imaging (CSI) is one of the largest new programs at The University of Texas MD Anderson Cancer Center within the Division of Diagnostic Imaging. The goal of this department and its research program is to develop new methodologies to visualize the cellular, biochemical, and genetic processes that contribute to the development and progression of cancer and to translate these discoveries into the clinic.
Dr. Loukia Karacosta's lab focuses on poorly characterized processes such as senescence and epithelial-mesenchymal transition (EMT) and aims to dissect how phenotypic plasticity drives the dynamics of drug resistance, therapy response and subsequent disease progression in the tumor microenvironment as a whole. By leveraging cancer systems biology approaches and single-cell technologies like mass cytometry (CyTOF), multiplexed imaging, live imaging and computational tools, we aim to interrogate the complex biology and spatiotemporal dynamics of therapy resistance in various cancer systems such as: cell lines, patient-derived organoids and tissue explants and longitudinal clinical specimens. The overall goal is to utilize innovative approaches of cancer systems biology to develop tools at the translational forefront of cancer systems research, towards predicting and counteracting mechanisms of drug resistance and evaluating – at a personalized level – disease status and response to treatment in cancer patients.
Eligibility Requirements:
Prospective candidates with a variety of backgrounds are welcome to apply with a Ph.D. in fields such as cancer biology, molecular and cellular biology, biomedical engineering, biochemistry, and computational biology/bioinformatics from an accredited institution of higher learning. The ideal candidate would have at least some prior experience in areas like cancer cell biology, cancer systems biology, preclinical cancer models, use of immortalized cell lines, organoids and tissues, analysis of advanced imaging techniques and single-cell data, computational biology or bioinformatics with interest in developing specialized skills in generating high-dimensional data and downstream analysis with translational applications. Although not required, expertise in single-cell analysis (e.g. CyTOF and RNAseq), multiplexed imaging and cancer systems biology is highly desirable.
Mentor Matching:
This position reports to Loukia Karacosta, Ph.D.
Additional Application Information:
Please contact Heidi Bradley (HLBradley@mdanderson.org) or CSIEducation@mdanderson.org for additional information or any questions.
Req #: 710509-202107260719
Job Title: Postdoctoral Fellow
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The department of Cancer Systems Imaging (CSI) is one of the largest new programs at The University of Texas MD Anderson Cancer Center within the Division of Diagnostic Imaging. The goal of this department and its research program is to develop new technologies to visualize and assess the cellular, biochemical, and genetic processes that contribute to the progression and regression of cancer and to translate these discoveries into the clinic.
The John S. Dunn Laboratory for Imaging Sciences within the Department of Cancer Systems Imaging at MD Anderson Cancer Center is seeking applicants for a Postdoctoral Fellow to conduct cutting edge research at the interface of image-guided tumor ablation and immunology. The candidates must have a passionate enthusiasm for research and have a strong background in cancer biology or related fields. The fellow will work under the co-mentorship of Dr. Chun Li, Professor in Cancer Systems Imaging and Dr. Alan Wang, Associate Professor in the Department of Cancer Biology.
Eligibility Requirements:
The ideal candidate will have a Ph.D. in immunology, cancer biology, molecular/cellular biology or related disciplines from an accredited institution of higher learning. The ideal candidate should be self-motivated, working as a team, and have excellent communication skills.
Mentor Matching:
This position reports to Chun Li, Ph.D. View Dr. Li's research profile.
Additional Application Information:
Please send your CV and cover letter to CSIEducation@mdanderson.org and/or Heidi Bradley (HLBradley@mdanderson.org).
Req #: 710509-202108161755
Job Title: Postdoctoral Fellow
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The department of Cancer Systems Imaging (CSI) is one of the largest new programs at The University of Texas MD Anderson Cancer Center within the Division of Diagnostic Imaging. The goal of this department and its research program is to develop new methodologies to visualize the cellular, biochemical, and genetic processes that contribute to the development and progression of cancer and to translate these discoveries into the clinic.
Dr. Charles Manning's laboratory focuses on the discovery and translation of radiopharmaceuticals for a wide-variety of uses in oncology and drug development. Trainees in the Manning lab are encouraged to participate in comprehensive, 'bench-to-bedside-to-bench' programs of research aimed at the discovery, prioritization, translation, and early clinical implementation of novel radiopharmaceuticals ranging from diagnostics to therapeutics. Trainees in the Manning lab access exceptional facilities dedicated to radiopharmaceutical science located in the Center for Advanced Biomedical Imaging (CABI) and Cyclotron Radiochemistry Facility (CRF). In particular, the CABI/CRF infrastructure enables seamless transition from radiopharmaceutical discovery to translation in one location.
Currently, we are seeking motivated individuals for NIH- and CPRIT-funded post-doctoral fellowship experiences in radionuclide theranostics with radiochemistry emphasis. Trainees will have the opportunity to develop and lead exciting, multi-disciplinary projects along the entire compendium of theranostics discovery and translation. In addition to research, training experiences will include unique education programs foundational to Theranostics, such as developmental radiochemistry, tracer adjudication and prioritization, preclinical and clinical molecular imaging, and advanced imaging physics.
Eligibility Requirements:
The ideal candidate would have a Ph.D. in chemistry, medicinal chemistry, or radiochemistry from an accredited institution of higher learning, with interest in developing specialized, multi-disciplinary skills in preclinical and clinical quantitative PET imaging, radiopharmaceutical translation, and theranostics.
Mentor Matching:
This position reports to H. Charles Manning, Ph.D. View Dr. Manning's research profile.
Additional Application Information:
Please direct any questions to CSIEducation@mdanderson.org.
Clinical Cancer Prevention
Req #: 600709-202108041617
Job Title: Postdoctoral Fellow
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The Department of Clinical Cancer Prevention has an immediate opening for a Postdoctoral position. Dr. Powel Brown is recruiting PhD or MD/PhD trained scientists to conduct breast cancer research to identify critical signal transduction molecules that can be targeted for the treatment or prevention of breast cancer. The candidate should have a PhD or MD/PhD degree and be familiar with basic techniques in molecular biology, cell biology, genetics, genomic profiling and computational biology. The postdoctoral fellow will work on a recently funded project to identify molecular targets for the treatment and prevention of breast cancer using genomic and proteomic techniques. Only candidates who have published work from their predoctoral studies and who are within 12 months of receiving their PhD will be considered. Scientists who have already received significant postdoctoral training will not be considered. The postdoctoral fellow will be expected to conduct independent research, to present their results at departmental and national meetings, and to prepare manuscripts for publication.
Learning Objectives:
Fellows will be trained in state-of-the-art signal transduction and genomic screening techniques and bioinformatic analysis, and will receive additional training in breast cancer biology, grant writing, bioinformatics, and systems biology.
Eligibility Requirements:
We seek a highly motivated individual with a PhD or MD/PhD degree and be familiar with basic techniques in molecular biology, cell biology, genetics, genomic profiling and computational biology.
Program Dates:
Begins September 1, 2021
Mentor Matching:
This position reports to Powel Brown, M.D., Ph.D.
Req #: 600709-202108091641
Job Title: Postdoctoral Fellow
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The Department of Clinical Cancer Prevention - Research at MD Anderson Cancer Center has one postdoc position open for studying genomic instability and immune responses in Peng Laboratory. Her laboratory research focuses on utilizing genetic, proteomic, and chemical approaches to understand the DNA damage response and repair network and develop preventive/therapeutic strategies to harness anti-tumor immunity by targeting the DNA repair network through the interconnected adaptive (neoantigen/mutanome dependent) and innate (neo-antigen/mutanome-independent) immune responses. The post-doc will work under the supervision of Dr. Guang Peng on and biological projects with both mechanistic and translational significance that may impact on both cancer prevention and therapy and have the opportunity to publish in high-impact research journals.
Learning Objectives:
The postdoctoral fellow will work under the supervision of Dr. Guang Peng. The primary research focus will be conducting genomic instability research using in vitro experimental methods for the mechanistic studies. The fellow will also gain extensive experience in preclinical animal models, clinical specimen validation and bioinformatic analysis using the TCGA database and chemical compounds’ databases.
Eligibility Requirements:
We seek a highly motivated individual with a Ph.D. in molecular biology/cancer biology.
Program Dates:
August 2021
Mentor Matching:
This position reports to Guang Peng, M.D., Ph.D. View Dr. Peng's research profile.
Additional Application Information:
Selected recent publications related to the projects for this postdoc position from Peng Laboratory:
Shen J, Peng Y, Wei L, Zhang W, Yang L, Lan L, Kapoor P, Ju Z, Mo Q, Shih IeM, Uray IP, Wu X, Brown PH,
Shen X, Mills GB, Peng G. ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to
PARP Inhibitors. Cancer Discov. 2015 Jul;5(7):752-67. PMID: 26069190; PMCID: PMC4497871 (Cancer
Discovery Cover Story)
Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D. Nagel, Jun Zou, Chen
Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jingsong Liu, Leona D. Samson,
Jaffer A. Ajani, Guomin Li, Han Liang, Xuetong Shen, Gordon B. Mills, and Guang Peng. ARID1A deficiency
promotes mutability and potentiates anti-tumor immunity unleashed by immune checkpoint blockade.
Nature Med. 2018 May;24(5):556-562. PubMed PMID: 29736026; PMCID: PMC6076433.
Hsieh H, Zhang W, Lin S, Yang W, Wang J, Shen J, Zhang Y, Lu Y, Wang H, Yu J, Mills G, Peng G. Systems
biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery. Nat
Commun. 2018 Sep 28;9(1):3982. PMID:30266942; PMCID: PMC6162282.
Shen J, Zhao W, Ju Zhenlin, Wang L, Peng Y, Labrie M, Yap T, Mills G, Peng G. PARPi triggers the STINGdependent
immune response and enhances the therapeutic efficacy of immune checkpoint blockade
independent of BRCAness. Cancer Research. 79 (2):311-319, 01/2019. PMID:30482774
Wang L, Yang L, Wang C, Zhao W, Ju Z, Zhang W, Shen J, Peng Y, Clemens A, Luu Yen T, Song S, Yap T,
Ajani J, Mills G, Shen X, Peng G. Inhibition of the ATM-Chk2 axis promotes cGAS/STING signaling in
ARID1A-deficient tumors. J Clin Invest. 2020 In Press
Req #: 600709-202110211635
Job Title: Postdoctoral Fellow
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The Department of Clinical Cancer Prevention - Research at MD Anderson Cancer Center has one post-doc position open for studying cancer diagnostics and therapeutics in the Hanash Laboratory. The laboratory focuses on the application of Omics technologies to define signatures for cancer early detection and for identifying novel targets for therapeutics by mining the cancer surfaceome. The post-doc will work under the supervision of Dr. Hanash on molecular profiling of a type of cancer.
Learning Objectives:
The postdoctoral fellow will work under the supervision of Dr. Hanash. The primary research focus will be conducting in vitro and in vivo experiments to test the performance of diagnostic and therapeutic targets resulting from the discovery work. The fellow will also gain extensive experience in Omics technologies. preclinical animal models, clinical specimen validation and big data analysis.
Eligibility Requirements:
We seek a highly motivated individual with a PhD or MD in molecular biology/cancer biology.
Program Dates:
November 2021
Mentor Matching:
This position reports to Samir Hanash, M.D., Ph.D. View Dr. Hanash's research profile.
Additional Application Information:
Guida F, et al Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins. JAMA Oncol 2018 Oct 1;4(10):e182078
Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz LA Jr, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N Science. 2018 Feb 23;359(6378):926-930.
Fahrmann FF, Vykoukal J, Fleury A, Tripathi S, Dennison JB, Murage E, Wang P, Yu CY, Capello M, Creighton CJ, Do KA, Long JP, Irajizad E, Peterson C, Katayama H, Disis ML, Arun B, Hanash SM. Association Between Plasma Diacetylspermine and Tumor Spermine Synthase With Outcome in Triple-Negative Breast Cancer. JNCI Journal of the National Cancer Institute 112(6):607-616, https://doi.org/10.1093/jnci/djz182, 6/2020. e-Pub 6/2020. PMCID: PMCPMC7301069.
Katayama H, Kobayashi M, Irajizad E, Sevillarno A, Patel N, Mao X, Rusling L, Vykoukal J, Cai Y, Hsiao F, Yu CY, Long J, Liu J, Esteva F, Fahrmann J, Hanash S Protein citrullination as a source of cancer neoantigens. J Immunother Cancer. 2021 Jun;9(6):e002549. doi: 10.1136/jitc-2021-002549.
Critical Care - Research
Req #: 600658-202109271859
Job Title: Postdoctoral Fellow
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A Postdoctoral position for NIH-funded project is available in the laboratory of Dr. Jyotika Sharma at MD Anderson Cancer Center. The major research focus of Sharma laboratory is to understand neutrophil functions in regulation of inflammation. Using murine transgenic models and clinical samples for infectious and sterile immune disorders such as pneumonic sepsis, CGD, COPD, metabolic diseases and breast cancer our laboratory is investigating the mechanisms of neutrophil extracellular trap (NET) formation, granulopoiesis and neutrophil efferocytosis. With our recent mechanistic discoveries, a major thrust in the laboratory is therapeutic modulation of neutrophil-mediated responses in disease specific manner, a yet unmet clinical need. Using FDA approved drugs, novel anti-inflammatory biofactors isolated from helminth parasites; and small-molecule inhibitors we are engaged in identifying strategies to control pathological neutrophil responses without affecting the antimicrobial function of neutrophils.
Learning Objectives:
This project aims to generate mechanistic understanding of the metabolic reprogramming that affects formation of neutrophil extracellular traps (NETs) and inflammatory immune responses in human disease conditions; and determining how neutrophil metabolic landscape affects NET formation mediated by C-Type lectin receptor Mincle and its interaction with a newly discovered endogenous ligand. Successful candidate will benefit from a dynamic and collaborative research environment in the laboratory, mentoring and networking opportunities, interaction with clinical investigators, access to state of-the-art research facilities and clinical samples.
Eligibility Requirements:
Completed Ph.D. or MD/Ph.D. in immunology or any field relevant to the biology of human disease. The applicant will have research competence evident by relevant first author publications in respected field journals. Strong communication skills in English are essential.The position requires hands-on experience with primary cell culture, multicolour flow-cytometry, microscopy, immunostaining and mouse models of infection and disease. Prior experience with metabolic assays and animal models of immuno-metabolic disorders is desirable but not required.
Program Dates:
Position is available immediately.
Mentor Matching:
This position reports to Jyotika Sharma, Ph.D. View Dr. Sharma's research profile.
Comparative Medicine
No positions are currently available in this department. Check back later for new opportunities.
Dermatology
No positions are currently available in this department. Check back later for new opportunities.
Diagnostic Imaging
No positions are currently available in this department. Check back later for new opportunities.
Endocrine Neoplasia & Hormonal Disorders
Req #: 600703-202108171244
Job Title: Postdoctoral Fellow
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The Hofmann laboratory in the Department of Endocrine Neoplasia studies the molecular mechanisms of acquired resistance to targeted therapies in aggressive thyroid cancers, in particular anaplastic thyroid cancer (ATC). We have recently identified a number of pathways and relevant molecules inducing resistance to kinase inhibitors. Funded projects include studying the role of specific EMT drivers and other transcription factors in cell growth and metastasis and interrogating the tumor-stroma interface. We are using human/mouse cell lines and genetically engineered mouse models of ATC to test the efficacy of novel drugs in vitro and in vivo that might prevent resistance to therapies.
Learning Objectives:
We are seeking applicants for a post-doctorate position in the areas of cellular and molecular biology. The fellow will be using in vitro and in vivo models to study the function of certain genes and secondary mutations that induce thyroid cancer cell growth and metastasis. Models include 2D and 3D culture systems and GEMM. In addition, we expect the postdoctoral fellow to gain expert-level skills in CyTOF, scRNA-Seq, other omics, and work in consultation with in house computational scientists. The fellow will develop a new independent project that will extend the studies into clinically relevant and fundable areas. The fellow is expected to write and prepare research presentations, manuscripts and grant proposals.
Eligibility Requirements:
The applicant must have a minimum of a Ph.D. degree in biochemistry/cell/molecular biology, have at least three years of prior experience in basic laboratory techniques such as tissue culture, molecular analysis of DNA, RNA, and protein, and mouse tumor models. Preparation of samples for next-generation sequencing is recommended. A minimum of two previous publications is expected.
Program Dates:
The appointment is immediately available. Initial appointment is for one year and is renewable.
Mentor Matching:
This position reports to Marie-Claude Hofmann, Ph.D., MPhil with ample opportunity for co-mentoring from other faculty collaborators. View Dr. Hofmann's research profile.
Req #: 600703-202108191429
Job Title: Postdoctoral Fellow
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The Hofmann laboratory in the Department of Endocrine Neoplasia studies the molecular mechanisms of acquired resistance to targeted therapies in aggressive thyroid cancers, in particular anaplastic thyroid cancer (ATC). We have recently identified a number of pathways and relevant molecules inducing resistance to kinase inhibitors. Funded projects include studying the role of specific EMT drivers and other transcription factors in cell growth and metastasis and interrogating the tumor-stroma interface. We are using human/mouse cell lines and genetically engineered mouse models of ATC to test the efficacy of novel drugs in vitro and in vivo that might prevent resistance to therapies.
Learning Objectives:
We are seeking applicants for a post-doctorate position in the areas of cellular and molecular biology. The fellow will be using in vitro and in vivo models to study the function of certain genes and secondary mutations that induce thyroid cancer cell growth and metastasis. Models include 2D and 3D culture systems and GEMM. In addition, we expect the postdoctoral fellow to gain expert-level skills in CyTOF, scRNA-Seq, other omics, and work in consultation with in house computational scientists. The fellow will develop a new independent project that will extend the studies into clinically relevant and fundable areas. The fellow is expected to write and prepare research presentations, manuscripts and grant proposals
Eligibility Requirements:
The applicant must have a minimum of a Ph.D. degree in biochemistry/cell/molecular biology, have at least three years of prior experience in basic laboratory techniques such as tissue culture, molecular analysis of DNA, RNA, and protein, and mouse tumor models. Preparation of samples for next-generation sequencing is recommended. A minimum of two previous publications is expected.
Program Dates:
The appointment is immediately available. Initial appointment is for one year and is renewable.
Mentor Matching:
This position reports to Marie-Claude Hofmann, Ph.D. View Dr. Hofmann's research profile.
Req #: 600703-202201241411
Job Title: Postdoctoral Fellow
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The Adrenal Tumors team at MD Anderson actively studies molecular features of adrenal tumors and runs multiple novel clinical trials to identify new treatment options for patients with advanced adrenal malignancies. We have multiple clinical trials and translational projects done within MD Anderson as well as in collaboration with other centers nationally and internationally.
Learning Objectives:
We are seeking applicants for a post-doctorate position in the areas of adrenal tumors. The fellow will be extracting and analyzing clinical data and correlate the data with translational projects when applicable. The fellow will be also supporting and participating in educational activities and research seminars to gain more in depth experience related to adrenocortical tumors. There is an expectation to collaborate with existing laboratory and translational findings to help collecting, analyzing biospecimens via different techniques including immunohistochemistry, gene sequencing, and work in consultation with in house computational scientists and biostatisticians.. The fellow will develop a new independent project that will extend the studies into clinically relevant and fundable areas. The fellow is expected to write and prepare research presentations, manuscripts and grant proposals.
Eligibility Requirements:
The applicant must have an MD degree and a Ph.D. degree focused on adrenal neoplasia. Reasonable competency is favored in tissue culture, molecular analysis of DNA, RNA, and protein, and mouse tumor models. Preparation of samples for next-generation sequencing is recommended. A minimum of two previous publications is expected.
Program Dates:
The appointment is immediately available. Initial appointment is for one year and is renewable.
Mentor Matching:
This position reports to Mouhammed Amir Habra, M.D., with ample opportunity for co-mentoring from other faculty collaborators.
Epidemiology
Req #: 106100-202108131630
Job Title: Postdoctoral Fellow
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The Nead group is based in the departments of Epidemiology (primary) and Radiation Oncology (secondary). The Nead group currently has a funded open postdoctoral fellow position to study the association of somatic (acquired) genetic changes with cancer development, cancer treatments, and cancer outcomes. Developing research has demonstrated that normal tissues commonly acquire genetic changes and that these acquired variants may have implications for health and treatment outcomes. Our group studies acquired genetic changes in normal tissues (e.g. breast tissue, blood) and how these acquired genetic changes are influenced by cancer treatments (e.g. chemotherapy and radiation therapy), how they impact cancer outcomes (e.g. survival, toxicity), and how they are modulated by cancer risk factors (e.g. age, obesity, smoking). We have ongoing projects available for a postdoctoral fellow to take the lead on as well as ample opportunity and resources for the fellow to explore new avenues of independent research. The Nead group has significant computational resources, wet laboratory space, access to a wide array of clinical samples and data, and the support of a full-time computational scientist, research analyst, and laboratory research assistant. Additionally, we support a rich learning environment with multiple active trainees from the masters to M.D. and/or Ph.D. level.
Learning Objectives:
Gain or advance skills in the analysis of genotype and sequencing data, specifically surrounding the study of acquired genetic changes using advanced sequencing techniques and bioinformatic approaches
Gain or advance skills in the analysis of clinical data as it relates to patient level genetics and genomics
Learn to develop independent lines of research
Advance skills in study design, data analysis and interpretation
Present at national and international conferences
Improve manuscript writing skills
Develop skills in fellowship application and grant writing in order to advance career to the desired next step
Eligibility Requirements:
PhD and/or MD or equivalent with a degree and/or significant experience in molecular/genetic epidemiology, computational biology, bioinformatics, data science, or a related field. A computational background and proficiency in at least one scripting language (e.g. R, Python) and at least basic knowledge of biostatistics are required. Experience working with genotyping and/or sequencing data, multi-dimensional datasets, and/or clinical data are desired. A proven track record of publications and proficiency in writing manuscripts is required. The ideal candidate has clear career goals, whether in academic or industry, that we can work together to achieve. Proficiency in spoken and written English is highly desired.
Program Dates:
The appointment is immediately available for a forty hours per week position. Two-year minimum commitment with additional commitment reviewed annually.
Mentor Matching:
This position reports to Kevin T. Nead, M.D., MPhil with ample opportunity for co-mentoring from other faculty collaborators.
Req #: 106100-202201141814
Job Title: Postdoctoral Fellow
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The postdoctoral scholar will primarily work with Dr. Sanjay Shete. On-going projects in Dr. Shete’s group include cancer survivorship, trends and barriers HPV vaccination, breast and cervical cancer screening, smoking cessation, genetic implications in cancer outcome, treatment, and survivorship. The postdoctoral scholar will study pregnancy health risk (mental and physical) of women with a pediatric cancer history, provider’s perspective towards HPV vaccine recommendation, screening adherence among south Asian cancer survivors.
Learning Objectives:
Gain expertise and services on behavioral research-related issues, data management, analysis, and interpretation.
Advance skills in study design, data analysis, and interpretation.
Develop and/or recommend program intervention, prevention, and/or control strategies.
Present at national and international conferences.
Improve manuscript writing skills.
Develop skills in fellowship application and grant writing in order to advance career to the desired next step.
Eligibility Requirements:
Ph.D. in Epidemiology, Behavioral Sciences, Public Health, or Social Science or MD with significant experience in areas mentioned.
Strong data analysis skills.
Advanced training in research methodology.
Excellent oral presentation and writing skills
Strong work ethic and commitment to becoming an independent scientist.
Defined career goals and research focus including (but not limited to) HPV vaccination, maternal health, and cancer survivorship.
Program Dates:
The appointment is immediately available for forty hours per week position. Two- year minimum commitment with additional commitment reviewed annually.
Mentor Matching:
This position reports to Sanjay S. Shete, Ph.D.. View Dr. Shete's research profile.
Epigenetics
Req #: 185800-202108201538
Job Title: Postdoctoral Fellow
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The University of Texas MD Anderson Cancer Center invites applications for postdoctoral fellowships in experimental cancer biology, CRISPR, and functional genetics/epigenetics starting immediately. Using state-of-the-art gene-editing and functional genomics/proteomics techniques, we seek to identify genetic and epigenetic biomarkers for human cancer precision medicine, synthetic lethal and resistance mechanisms underlying disease development and signal transduction at the systems level. The postdoctoral research will be performed in a highly interdisciplinary and collaborative environment with world-class experts and advanced technologies and facilities, which provide unique and ideal career development opportunities for postdocs.
Eligibility Requirements:
Applicants should have a recent Ph.D. degree (or equivalent) in molecular biology, cancer biology, genetics/epigenetics, immunology, or relevant fields. We are interested in passionate and self-motivated candidates who ask fundamentally important questions and are bold in taking innovative approaches. Candidates should have previous expertise with tissue culture. Experience with high-throughput biology, CRISPR screens and next-generation sequencing is a plus.
Mentor Matching:
This position reports to Nidhi Sahni, Ph.D., a faculty member and recognized leader in cancer genetics and systems biology at MD Anderson Cancer Center. Dr. Sahni has received numerous prestigious awards and strong funding support, including AACR NextGen Star, Sloan Scholar Award, CPRIT Scholar Award, NIH Outstanding Investigator Award (MIRA), DoD grant, Pinnacle Research Award, Rising STARs Award, among others.
Recent representative publications include Cancer Cell (2020), 37: 371-86; Cell (2015), 161: 647-60; Nature Rev Genet (2017), 18: 395-410; Cancer Cell (2018), 33: 450-462; Cell (2015), 161: 661-73; Cell (2017), 168: 856-66; Nature Commun. (2018), 9: 1317. View Dr. Sahni's research profile.
Req #: 185800-202108251556
Job Title: Postdoctoral Fellow
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A funded postdoctoral fellowship is available in the laboratory of Dr. Shawn B. Bratton at The University of Texas MD Anderson Cancer Center. Research on protein complexes involved in caspase activation and autophagosome formation will be carried out in the Department of Epigenetics and Molecular Carcinogenesis in Smithville. The department (near Austin, TX) is one of MD Anderson's largest and most successful fundamental research departments.
Eligibility Requirements:
Applicants should have a recent Ph.D. degree in biochemistry or a highly related field, one or more first-authored publications in highly regarded scientific journals, and proven proficiency in written and spoken English. Experience with mouse modeling, mammalian cell culture, recombinant protein purification, and Western blot analysis is an advantage.
Mentor Matching:
This position reports to Shawn Bratton, Ph.D. View Dr. Bratton's research profile.
Additional Application Information:
For more information, visit Dr. Bratton's laboratory website.
Req #: 185800-202111091811
Job Title: Postdoctoral Fellow
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Dr. Ellen Richie in the Department of Epigenetics and Molecular Carcinogenesis at MD Anderson Cancer Center invites applications for a postdoctoral fellowship focusing on identifying cellular and molecular mechanisms of thymus development and involution as well as cross-talk between thymic epithelial cells and thymocytes. These studies will utilize state-of-the-art image analysis, flow cytometry, single cell RNAseq and biochemical techniques to achieve these goals.
Learning Objectives:
The research environment is highly interactive and interdisciplinary with collaborations ongoing within the institution and with world-class experts at other institutions. The postdoctoral fellow will learn to work independently as well as collaboratively to advance their career development. Opportunities to network with members of the research community will be provided by frequent interactions with collaborating labs and by presentations given at national and international conferences. The training experience will provide the postdoctoral fellow the laboratory expertise, writing and speaking skills to establish and independent laboratory in academia or industry.
Eligibility Requirements:
Applicants should have been awarded the PhD degree within the past two years in the field of immunology and should be self-motivated, innovative, trust worthy, careful and diligent in their research performance.
Mentor Matching:
This position reports to Ellen R. Richie, Ph.D. View Dr. Richie's research profile.
Req #: 185800-202112140838
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position in epigenetic regulation and the DNA Damage response (DDR) in normal and malignant hematopoiesis is immediately available in the lab of Dr. Margarida Santos. The research will focus on the intersection of epigenetics and the DDR in acute myeloid leukemia as well as diffuse large B cell lymphoma. The long term goal is to understand the mechanisms through which Epigenetic regulation and its interplay with the DDR occurs during normal differentiation and how these processes become disrupted in human diseases and use this information to develop specific and potent therapeutic strategies.
Learning Objectives:
Training and research activities will include work with genetic mouse models of acute myeloid leukemia and diffuse large B cell lymphoma, as well as human cell lines and patient derived samples of these two models of cancer. In addition, techniques as RNA sequencing and chromatin immunoprecipitation sequencing will also be performed among other molecular biology techniques. Fluorescent microscopy and confocal microscopy are also components of the research program.Our lab is a part of the Center for Cancer Epigenetics at MD Anderson Cancer Center, and we continue to advance our efforts to define how Epigenetic Regulation and the DNA damage response contribute to normal hematopoiesis as well as drive malignant transformation in Blood Cancers.
Eligibility Requirements:
Candidate must be a recent Ph.D. or MD/Ph.D. graduate in biochemistry, genetics, immunology, cancer biology, or similar field. An excellent publication record (only candidates with one or more first-authored publications in a high impact journal(s) will be considered), along with experience in generating/characterizing mouse models, flow cytometry, retroviral transduction, mammalian cell culture and next generation sequencing is required. Previous experience in scientific writing or grant preparation in English is required.
Mentor Matching:
This position reports to Margarida Santos, Ph.D. View Dr. Santos' research profile.
Experimental Radiation Oncology
Req #: 198100-202107181130
Job Title: Postdoctoral Fellow
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Postdoctoral positions are available immediately to work in the area of DNA damage repair and cancer biology. The lab focuses on the roles of tumor suppressor genes and oncogenes in DNA repair and other signaling pathways involved in tumor initiation, progression and metastasis. The approaches we take range from mammalian cell culture, molecular biology, biochemistry to mouse genetics. We also conduct large-scale proteomic studies and gRNA screens to explore various cancer related signal transduction pathways.
Eligibility Requirements:
An individual holding a recent Ph.D. or equivalent doctorate who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator.
Mentor Matching:
The position reports to Junjie Chen, Ph.D.
Additional Application Information:
We seek applicants who are self-motivated and career-oriented to join an exciting and highly interactive research team. We have track record of training the best and the brightest postdoctoral fellows who become independent group leaders in the United States and other countries. The research environment at MD Anderson is outstanding and nurturing, especially for applicants who are interested in cancer biology and translational collaborations.
Req #: 198100-202107181120
Job Title: Postdoctoral Fellow
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Postdoctoral fellow positions are available for highly motivated candidates with a background in molecular/cellular biology, epigenetics, immunology or cancer mouse modeling. Projects will focus on the biology and genetics of prostate cancer, the identification of novel therapeutic targets, and the mechanism underlying metastasis and treatment resistance. We study these areas by using genetically engineered mouse models, transcriptional profiling, single-cell based analysis as well as other traditional biochemical, genetic, molecular and cell biological approaches.
Eligibility Requirements:
A Ph.D. degree in Biochemistry, Molecular Biology or equivalent is required. Applicants with good publication record and relevant research experience with epigenetics, immunology, or single cell sequencing are preferred. We highly value hard work, curiosity, innovation, teamwork and professional development in combination with a healthy work/life balance. The salary will be based on the NIH postdoc salary scale. The postdoc candidates should expect to join the lab in six months.
Mentor Matching:
The position reports to Di Zhao, Ph.D. View Dr. Zhao's research profile.
Additional Application Information:
View Dr. Zhao's lab website.
Req #: 198100-202107181110
Job Title: Postdoctoral Fellow
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The putative postdoc researcher will have the opportunities to work on various projects studying the roles of ferroptosis (a form of regulated cell death induced by lipid peroxidation) in tumor suppression and cancer therapy (please visit our lab webpage for detailed introduction on research projects https://www.mdanderson.org/research/departments-labs-institutes/labs/gan-laboratory.html). Qualified candidates should have strong background in one or more of the following areas: molecular/cell biology, biochemistry, metabolism, cancer genetics, or using Mass Spectrometry-related technologies to study metabolism.
Eligibility Requirements:
We prefer candidates who are about to graduate with PhD or MD/PhD degree, or have graduated within the last 12 months. A track record of excellent first author publication during PhD training is essential.
Mentor Matching:
The position reports to Boyi Gan, Ph.D. View Dr. Gan's research profile.
Req #: 198100-202108301133
Job Title: Postdoctoral Fellow
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Postdoctoral research fellow to carry out studies in translational breast cancer research.The laboratory focuses on identifying alterations with functional significance to the development and progression of breast cancer and translating results using transgenic mouse models as well as patient derived xenograft models. Specific pathways that examine the alteration of the G1/S transition and upregulation of IL-6 will be interrogated in these mouse model systems. Technologies include transgenic mouse modeling, single cell RNA sequencing, immune profiling and in vivo drug studies.
Learning Objectives:
In addition to wet bench and mouse model experiments, the post-doc will also have the opportunity to work with clinical investigators in the breast medical oncology and breast surgical oncology departments to learn how best to translate their pre-clinical work into clinical trials.
Eligibility Requirements:
Applicants must have a recent Ph.D. (or equivalent) with experience in cancer genomics, cell
biology, biochemistry, genetics or related fields. Applicants must have at least one first author
publication in a high quality journal as well as a high level of written and oral communication skills in
English. Experience working with mice is preferred.
Mentor Matching:
The position reports to Khandan Keyomarsi, Ph.D. View Dr. Keyomarsi's research profile.
Additional Application Information:
Interested applicants should submit a cover letter specifying past accomplishments, a curriculum vitae, and the contact information of three references to Dr. Keyomarsi at kkeyomar@mdanderson.org.
Req #: 198100-202109280840
Job Title: Postdoctoral Fellow
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The MD Anderson Cancer Center TRIUMPH (Translational Research in Multi-Disciplinary Program) Postdoctoral Fellowship provides training in clinical and translational research. The immediate goal of this program is to recruit talented and productive Ph.D. students from top graduate programs to provide continued training in clinical and/or translational cancer research through didactic course work, clinical rotations, and unique, interdisciplinary mentorships. A long-term goal of this program is to produce translational scientists who can be teamed with suitable physician scientists to PI a translational research laboratory.
This is a three-year training program. During the first six weeks of the program, fellows will interview with faculty on our mentoring committee to select a mentor and lab of their choosing. Once a mentor is selected and a research project is identified, the fellow will work with his/her mentor to identify additional committee members to guide them in their research and training. Fellows will participate in a series of didactic course work offered at the MD Anderson UTHealth Graduate School (GSBS) and strategically matched clinical rotations, while pursuing research in a basic or translational research laboratory. The TRIUMPH postdoc will earn a certificate upon successful completion of the program.
Eligibility Requirements:
Early-Stage Post-Doctoral Fellows:
Ph.D. or M.D./Ph.D. from a top graduate program (U.S. or abroad) in any of the life or natural sciences within the last three years
Dedication to pursue translational cancer research
Junior post-doctoral fellows (less than one and a half years of experience) and graduate students within one year of their anticipated defense date are encouraged to apply
Publications in top tier journals (must have at least one accepted or published first or co-first author paper in a journal with an impact factor >8 at the time of application)
United States citizenship or permanent residency is not required. All foreign fellows must have an active visa for the duration of the fellowship
Established Post-Doctoral Fellows:
Ph.D. or M.D./Ph.D. from a top graduate program (U.S. or abroad) in any of the life or natural sciences
Dedication to pursue translational cancer research
Must have no more than 3 years of post-doctoral experience by the time one starts our program if accepted
Has two or more first or co-first author papers in journals with an impact factor of >8. At least one publication should stem from previous post-doctoral work
United States citizenship or permanent residency is not required. All foreign fellows must have an active visa for the duration of the fellowship
Mentor Matching:
The position reports to Khandan Keyomarsi, Ph.D. View Dr. Keyomarsi's research profile.
Experimental Therapeutics
Requisition Number: 404400-202111120850
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Program/Position Description:
The laboratory of Drs. Robert Bast and Zhen Lu in the Department of Experimental Therapeutics is seeking a post-doctoral fellow to study on tumor biology. Our laboratory explores the functions of tumor suppressor genes, the mechanisms of tumorigenesis and chemoresistance. These studies provide a rational and basis for the development of therapeutic peptides.
Learning Objectives:
Under the supervision of the faculty mentor, the new post-doc will focus on cellular and chemical biology, learn and develop the molecular technologies for peptide synthesis.
Eligibility Requirements:
An individual holding a recent PH.D. or equivalent doctorate who is seeking an appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator.
Dates or Training Schedule:
January 4, 2021 - January 31, 2022
Mentor Matching:
This position reports to Zhen Lu
Req #: 404400-202107181110
Job Title: Postdoctoral Fellow
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The laboratory of Dr. Waldemar Priebe in the Department of Experimental Therapeutics is seeking a post-doctoral fellow to participate in the drug discovery and development program. Our laboratory focuses on drug resistant forms of cancer. Such studies provide a rational for drug design and preclinical data for the future translational and clinical research.
Our long-term goal is to development novel anticancer agents and understand their molecular mechanism(s) of action.
Learning Objectives:
Under the supervision of the faculty mentor, will study in vitro and in vivo novel potential anticancer drugs.
Eligibility Requirements:
An individual holding a recent Ph.D. or equivalent doctorate who is seeking an appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator.
Program Dates:
August 1, 2021 - July 30, 2022
Mentor Matching:
The position reports to Waldemar Priebe, Ph.D. View Dr. Priebe's research profile.
Req #: 404400-202108191426
Job Title: Postdoctoral Fellow
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The laboratory of Dr. Bulent Ozpolat in the Department of Experimental Therapeutics is seeking a post-doctoral fellow to study pharmacokinetics, apoptosis and atophagy as cellular death mechanism. Our laboratory explores the mechanisms of cancer cell survival, tumorigenesis and tumor progression and is focused on identifying signaling pathways regulating proliferation, invasion, drug resistance, apoptosis and autophagy. These studies provide a rational and basis for the development of therapeutic applications using RNA-inteference (siRNA and microRNA), oligonucleotides, (antisense), chemotherapeutic agents and small molecules in cancer and a wide variety of other diseases. Nanomedicine functions as a critical bridge that will connect basic science discoveries and clinical applications by enabling the development of highly effective targeted therapies utilizing nanoparticles that capable of delivering therapeutic payloads to disease sites and targeting identified molecular pathways.
Our long-term goal is to development clinically relevant, non-toxic, tumor-targeted nano-therapeutics agents that can be used translated into the clinic to improve the treatment options for the patients therapy and further enhance efficacy of current regimens.
Learning Objectives:
Under the supervision of the faculty mentor, will study pharmacokinetics, apoptosisand autophagy as cellular death mechanisms induced by novel compounds and siRNA and will have experience in laboratory techniques, including cell culture small interfered RNA (siRNA) and micro RNA-based gene silencing/regulation, pharmacokinetics, apoptosis and autophagy as cellular death mechanisms fluorescent microscopy, confocal imaging, and flow cytometry applications.
Eligibility Requirements:
An individual holding a recent Ph.D. or equivalent doctorate who is seeking an appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator.
Program Dates:
October 05, 2021 - September 31, 2022
Mentor Matching:
The position reports to Bulent Ozpolat, M.D., Ph.D. View Dr. Ozpolat's research profile.
Req #: 404400-202112030913
Job Title: Postdoctoral Fellow
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The laboratory of Dr. Gabriel Lopez in the Department of Experimental Therapeutics is seeking a post-doctoral fellow to study pharmacokinetics, apoptosis and atophagy as cellular death mechanism. Our laboratory explores the mechanisms of cancer cell survival, tumorigenesis and tumor progression and is focused on identifying signaling pathways regulating proliferation, invasion, drug resistance, apoptosis and autophagy. These studies provide a rational and basis for the development of therapeutic applications using RNA-inteference (siRNA and microRNA), oligonucleotides, (antisense), chemotherapeutic agents and small molecules in cancer and a wide variety of other diseases. Nanomedicine functions as a critical bridge that will connect basic science discoveries and clinical applications by enabling the development of highly effective targeted therapies utilizing nanoparticles that capable of delivering therapeutic payloads to disease sites and targeting identified molecular pathways.
Our long-term goal is to development clinically relevant, non-toxic, tumor-targeted nano-therapeutics agents that can be used translated into the clinic to improve the treatment options for the patients therapy and further enhance efficacy of current regimens.
Learning Objectives:
Under the supervision of the faculty mentor, will study pharmacokinetics, apoptosisand autophagy as cellular death mechanisms induced by novel compounds and siRNA and will have experience in laboratory techniques, including cell culture small interfered RNA (siRNA) and micro RNA-based gene silencing/regulation, pharmacokinetics, apoptosis and autophagy as cellular death mechanisms fluorescent microscopy, confocal imaging, and flow cytometry applications.
Eligibility Requirements:
An individual holding a recent PH.D. or equivalent doctorate who is seeking an appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator.
Program Dates:
March 1, 2022 - April 30, 2023
Mentor Matching:
The position reports to Gabriel Lopez, M.D. View Dr. Lopez's research profile.
Req #: 404400-202201101446
Job Title: Postdoctoral Fellow
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Two (2) postdoctoral positions are available in Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. These positions report to Dr. Zhen Fan, Professor in the Department of Experimental Therapeutics.
Learning Objectives:
We are seeking talented and highly motivated postdoctoral fellows, with strong passion for translational research and interest in entrepreneurship, to join our team in following research directions:
(1) Development of novel bispecific antibodies for cancer treatment. Primary research focus is to perform hands-on experiments to assess therapeutic activities of novel bispecific antibodies in preclinical models of mouse tumors and patient-derived xenograft tumors, and to gain insights underlying the mechanism of action of the bispecific antibodies;
(2) Development of antibody-guided exosomes for RNA delivery as a novel approach of cancer therapy. Primary research focus is to perform hands-on experiments testing in preclinical tumor models to redirect host preexisting noncancer immunity against infectious diseases towards cancer via targeted delivery of relevant RNA molecules and to gain mechanistic understanding of the approach.
The postdoctoral fellows will design, plan and execute the experiments, perform data analysis, and prepare manuscripts for publication. The postdoctoral fellows will report and discuss research progress with the principal investigator, present research findings regularly in lab meetings, and attend journal clubs and research seminars.
Eligibility Requirements:
Individuals with a PhD degree (or equivalent) in cancer biology, immunology, and/or experimental therapeutics with less than 2 year of postdoctoral experience. Experience in bioengineering and development of biologics related to immunology and cancer biology is a significant plus. Experience with rodent experimentation is required for these positions. Successful applicants should have strong organizational skills and ability to prioritize and manage multiple projects. Proven track record of publications, and excellent written and oral communication skills are required.
Dates or Training Schedule:
March 1, 2022 - February 28, 2023
Mentor Matching:
This position reports to Zhen Fan, M.D. View Dr. Fan's research profile.
Additional Application Information:
Consideration of applications will begin immediately and continue until the position is filled.
Gastrointestinal Medical Oncology
Req #: 600656-202108041620
Job Title: Postdoctoral Fellow
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- Plans, organizes, coordinates, directs and participates as a team member in research projects involving detection and elimination of gastro-esophageal cancers.
2. Collaborate with team members and apply scientific expertise in molecular biology, immunology and/or cancer biology to drive projects in a multidisciplinary and exciting research team environment. Has in-depth knowledge and skills to elucidate disease mechanisms and cell signaling pathways in GI malignancies.
3. Performs molecular biology experiments such as subcloning, genetic knockout or overexpression of target genes, ELISA, Western blotting, q-PCR, IP, CHiP assay, protein-protein or RNA-Protein interactions and drug screening; mouse handling such as tumor injection from clinical specimen, drug treatment and analyze all data as well as genetic mouse model handling.
4. Processes clinical samples such human blood, tissue, ascites and is be able to employ good cryopreservation techniques for future research. Performs basic histologic techniques on formalin-fixed tumor specimens.
5. Independently execute, interpret, and troubleshoot experiments to answer key scientific questions. Use data to make decisions and new hypotheses. Keep abreast of current and emerging technological and scientific advancements in the field.
6. Assists in preparation of drafts of research grants, manuscripts and grant reports.
7. Ensures that relevant data is collected at designed stages in the research process, is entered into database(s) and reported, as required.
Learning Objectives:
- understanding of biology of GI cancers
- ability to search and evaluate clinical and scientific literature
- ability to form and then defend hypotheses based on prior clinical or experimental data
- ability to effectively communicate findings in written and oral form
- ability to write persuasive grant applications
- ability to navigate scientific publication process
Eligibility Requirements:
An individual with a graduate degree in medicine, science or engineering field.
Program Dates:
Anticipated start date: September 1, 2021
Mentor Matching:
This position reports to Jaffer Ajani, M.D. and Shumei Song, M.D., Ph.D.
Genetics
Req #: 144300-202108171249
Job Title: Postdoctoral Fellow
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The Lozano laboratory has an open position for a postdoctoral fellow to study p53 genetic pathways in tumor progression.
Learning Objectives:
The individual will learn experimental methods related to the study of p53 genetic pathways in tumor progression using mice as a model system. They will work closely with the PI to learn how to write and submit manuscripts, write fellowship and grant applications, and present their work at national and international conferences. Towards the end of their postdoc training they will learn how to apply for faculty positions.
Eligibility Requirements:
Ph.D. or M.D./Ph.D. with a strong background in genetics, molecular biology or related fields
Mentor Matching:
This position reports to Guillermina Lozano, Ph.D.
Additional Application Information:
For more information please visit these websites:
Req #: 144300-202108171254
Job Title: Postdoctoral Fellow
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Tumor cells must endure diverse intrinsic and extrinsic stressors that perturb proteome homeostasis. By serving as a protein-folding buffer within the cell, the chaperone protein HSP90 supports protein homeostasis and enables tumor cells to survive and rapidly evolve resistance to therapies. For this, HSP90 must bind to diverse proteins and stabilize them within the cytoplasm. However, the specific mechanisms through which HSP90 fosters cancer evolution remain obscure. We will examine these HSP90-dependent mechanisms using multiomic systems approaches and functional genomics methodologies and, subsequently, we will validate the mechanisms we identify in mice. This strategy will identify novel cancer therapies that limit the ability of tumors to evolve resistance.
Learning Objectives:
The postdoctoral fellow will engage with the PI in understanding how the HSP90 chaperone is regulated in cancer and how it supports DNA repair in tumor cells. This will require deep interest in cell biology and signaling pathway biology. The PI will mentor the postdoctoral fellow in laboratory approaches that may be unfamiliar and in critical thought, experimental design and bringing new perspectives to the laboratory. Trainings that may be needed that are outside of the expertise of the PI will involved attending courses or engaging collaborative ventures. A major part of the learning objectives will involve optimizing scientific communication, both written and oral, which includes developing robust networks of colleagues to enhance one’s work in the laboratory, and to promote the trainee’s research program after leaving the laboratory.
Eligibility Requirements:
We seek highly motivated postdocs interested in functional proteomics, quantitative genetics, biochemistry, cell biology, or cancer biology. We welcome applicants from diverse backgrounds who wish to apply their expertise to biological systems and to contribute to the advancement of precision medicine. Minimum requirement is to have recently been awarded (within two years) a Ph.D., and proficiency in spoken and written English.
Mentor Matching:
This position reports to Georgios Karras, Ph.D.
Additional Application Information:
For more information please visit these websites:
Req #:144300-202108091632
Job Title: Postdoctoral Fellow
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The Navin laboratory has an open position for a postdoctoral fellow in computational biology in the department of Genetics at the MD Anderson Cancer Center in Houston, TX. The individual will work on the development of statistical methods to analyze large-scale single cell DNA and RNA sequencing datasets to study human cancer progression. This person will lead individual projects related to cancer evolution, invasion, metastasis or therapy resistance. Strong programming skills are required in languages such as Perl, Python and Matlab. Strong statistical skills in Rare also required, including knowledge of multivariate statistical methods, such as clustering, high-dimensional data reduction and phylogenetics. Good knowledge of Unix, Linux and Clusters is also necessary.
Learning Objectives:
The individual will learn cancer genomics and computational biology, particularly in relation to skills for analyzing large-scale single cell sequencing datasets. They will learn how to analyze and interpret data related to genome evolution in breast cancer. The postdoc will work closely with the Pl to learn how to write and submit manuscript, write fellowship and grant applications and apply for faculty positions.
Eligibility Requirements:
Ph.D. degree in computational biology, computer science, statistics or genomics
Mentor Matching:
This position reports to Nick Navin, Ph.D. View Dr. Navin's research profile.
Additional Application Information:
For more information please visit these websites:
Req #:144300-202108091633
Job Title: Postdoctoral Fellow
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Chronic pain is usually caused by disease or damage involving the somatosensory nervous system, adversely affecting millions of Americans. It is difficult to treat and remains a major clinical problem. Opioids, acting through opioid receptors, function as powerful analgesics. However, chronic opioid treatment causes hyperalgesia/analgesic tolerance and addiction, which have resulted in an opioid epidemic in the U.S. One position involves studying the mechanisms of chronic pain in mouse models and determining how these mechanisms could be utilized in therapeutic interventions of chronic pain.
Glioblastoma is a highly heterogeneous and lethal human brain tumor and is made up of multiple molecular subtypes, suggesting that therapy could be targeted to particular subtypes. Yet all newly diagnosed GBM patients are treated with a similar therapeutic regimen, which results in overall poor patient outcomes. The second project involves discovering mechanism-based therapeutic approaches for a molecularly-stratified glioblastoma tumor using mouse models and advanced drug-delivery systems.
Learning Objectives:
The postdoctoral fellow will engage with the Pl in understanding how REST regulates either chronic pain or glioblastoma in mouse models. This will require deep interest in pain research, cell biology and developmental biology, and depending on the project, on bioinformatic analyses. The Pl will mentor the postdoctoral fellow in laboratory approaches that may be unfamiliar, and in critical thought, experimental design and interpretation, but the fellow is expected at the same time to consistently undertake an active role in researching the literature and bringing new perspectives to the laboratory. Trainings that may be needed that are outside of the expertise of the Pl will involve attending courses or engaging in collaborative ventures. A major part of the learning objectives will involve optimizing scientific communication, both written and oral, which includes developing robust networks of colleagues to enhance one's work in the laboratory, and, equally importantly, to promote one's research program after leaving the laboratory.
Eligibility Requirements:
We are looking for a committed Postdoctoral Fellow to join our group to work on the mechanisms by which the transcriptional repressor REST regulates chronic pain and glioblastoma regulation.
Mentor Matching:
This position reports to Sadhan Majumder, Ph.D. View Dr. Majumder's research profile.
Additional Application Information:
For more information please visit these websites:
Req #:144300-202111191525
Job Title: Postdoctoral Fellow
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The Cancer Genomics and Evolution laboratory, headed by Prof. Peter Van Loo, has multiple positions open for postdoctoral fellows in computational biology. The laboratory is based in the department of Genetics at the MD Anderson Cancer Center in Houston, TX. Members of the Van Loo laboratory have co-authored 15 papers in Nature, Science or Cell. Recent successes include pan-cancer studies of the evolutionary history of cancer (Gerstung et al., Nature 2020), intra-tumor heterogeneity (Dentro et al., Cell 2021) and the mutational landscape in non-unique regions of the human genome (Tarabichi et al., Nature Biotechnology 2021).
The individual will spearhead projects in large-scale cancer genomics, with a focus on elucidating the evolutionary history of cancer metastases. The laboratory's research focuses on large-scale pan-cancer genomics to gain insight into the genes, mutational processes and evolution of cancer. Its work is highly data-driven, with a focus on large-scale data analysis to gain broad biological insight and on the development of computational methods to enable conceptually novel analyses. The research group is mostly computational with a small wet-lab component.
Learning Objectives:
The individual will learn cancer genomics and computational biology. They will develop key skills in analyzing large-scale sequencing datasets from a quantitative genomics and evolutionary perspective. The postdoc will work closely with the PI to learn how to write and submit manuscript, write fellowship and grant applications and apply for faculty positions.
Eligibility Requirements:
Ph.D. degree in computational biology (bioinformatics, genomics, biostatistics, …) and research experience in the field of cancer genomics, although we welcome applications from candidates with diverse educational backgrounds, including computational biology, physics and (bio)statistics, biology or medicine. Applicants must have a proven publication record. A computing background is not strictly necessary, but applicants must be keen to work in a dry setting. For applicants with computing experience, fluency in Linux, and excellent knowledge in at least one programming language is expected (R/BioConductor, Perl, Python, …). Prior experience with handling massively parallel sequencing data is considered an advantage.
Postdocs will spearhead projects in cancer genomics and tumor evolution. They are expected to lead their own project, contribute to other projects on a collaborative basis (both within the lab and with external collaborators) and guide PhD students in their research. The ability to work in a team is essential.
Please include a CV (max 3p.; including publication list)and a motivation letter (max. 1p).
Program Dates:
Start date between January 1st, 2022 and June 1st, 2022
Mentor Matching:
This position reports to Peter Van Loo, Ph.D.
Genitourinary Medical Oncology
Req #: 600655-202111170834
Job Title: Postdoctoral Fellow
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Program/Position Description:
A postdoctoral fellow position is available in the Department of Genitourinary Medical Oncology under the direct supervision of Dr. Guocan Wang. Research in the Wang Laboratory focuses on the role of transcriptional/epigenetic regulation and tumor microenvironment (TME) in the metastasis and therapeutic resistance of urothelial cancer (e.g., prostate cancer, bladder). The research in the Wang Laboratory will employ diverse research approaches and experimental models, including new technology tools such as CyTOF, imaging mass cytometry, histology, proteomics, transcriptomics (single-cell RNA), and epigenomics (single cell ATAC-seq) (see our recent publications Cancer Discovery 2016 Jan;6(1):80-95, Genes Dev. 2018 Sep 1; 32(17-18): 1105–1140, Oncogene 2021). Particularly, we have acquired existing and have generated novel genetically engineered mouse models for urothelial cancers and myeloid-derived suppressor cells.
Learning Objectives:
This postdoctoral fellow will focus on the role of histone modifiers and transcriptional factors/cofactors in cancer, and how the dysregulation of transcriptional/epigenetic program regulate tumor progression, metastasis, and therapeutic resistance through cancer cell-intrinsic mechanisms and crosstalk with tumor microenvironment. This postdoc will learn to use bioinformatic tools, genetically engineered mouse models (GEMM) and various experimental approaches.
Eligibility Requirements:
Applicants must have a recent Ph.D. or M.D./Ph.D. degree in a related biomedical field and strong interests and self-motivation for research. transcriptional
Dates or Training Schedule:
Position available immediately.
Mentor Matching:
This position reports to Guocan Wang.
Req #: 206100-202107181110
Job Title: Postdoctoral Fellow
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The role of immunological and epigenetic pathways in resistance and response to immune checkpoint therapy.
General Laboratory duties or procedures:
1. To work with animal and human samples (Handling, Treatments, Inoculation and Processing of samples for long-term storage)
2. Perform single cell RNA sequencing, able to run the data in different packages and analyze the tumor immune microenvironment
3. Perform ATAC-sequencing, able to run the data in different packages and analyze chromatin accesibilites
4. CyTOF staining and analyses of the data
5. Flow cytometry staining and analyses
6. Immunohistochemistry
7. Molecular biology techniques like PCR, RNA/DNA isolation, western blot and knock in/ out using CRISPR technology.
Learning Objectives:
1. To understand immunological pathways involved in reponse and resistance to immune checkpoint therapy in single cell level.
2. To understand the epigentic regulations of immune sub-populations.
3. To analyze the single cell RNA sequencing and ATAC sequencing data.
Eligibility Requirements:
PhD in Immunology or Bioinformatics
Mentor Matching:
This position reports to Sangeeta Goswami, M.D., Ph.D. See Dr. Goswami's research profile.
Req #: 600655-202108121716
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in Department of Genitourinary Medical Oncology at MD Anderson Cancer Center, Houston, TX. Our research is focused on understanding the molecular basis of primary and adaptive resistance mechanisms to immune checkpoint therapies in advanced prostate cancer. The laboratory focuses on addressing this issue using a wide range of tools from next-generation sequencing (WES, WGS, RNA-seq) and in vitro and in vivo immunologic assays (flow cytometry, mass cytometry, IHC). The candidate should be familiar with basic techniques in immunology, molecular biology, cell biology, and genomic profiling of tissues.
Learning Objectives:
The postdoctoral fellow will work under the supervision of Drs. Sumit Subudhi and Theocharis Panaretakis. The successful applicant is expected to develop an in-depth understanding of cancer immunology mouse models, T cell responses to tumors, and high dimensional analyses approaches as well as display increasing research independence.
Eligibility Requirements:
Candidates should be highly motivated individuals who have a recent Ph.D. degree or in the process of completing Ph.D. training and a solid background in Immunology, with preferred hand-on experience in flow/mass cytometry, molecular techniques, and mouse models of autoimmunity and/or anti-tumor immunity. Only candidates who have published work from their pre- and/or post-doctoral studies will be considered.
Experience of laboratory techniques in the fields of molecular biology and immunology.
Develop, analyze and validate data for assays using statistical methods.
Previous experience with SOPs and animal protocols.
Troubleshooting daily experiments.
Demonstrated ability for creative thinking and problem solving.
Demonstrated ability to work in a multi-disciplinary team.
Mentor Matching:
This position reports to Sumit Subudhi, M.D., Ph.D. See Dr. Subudhi's research profile.
Req #: 600655-202108121719
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is immediately available in the laboratory of Jianjun Gao, MD, PhD, in the Department of Genitourinary Medical Oncology. We are looking for highly self-motivated candidates with a recent PhD or MD/PhD degree, to investigate the resistance mechanism of immune checkpoint blockade therapy in genitourinary malignancies including bladder and kidney cancer, as well as development of novel combination strategies to improve therapy for genitourinary malignancies.
Successful candidate must be able to design novel projects, create hypothesis-driven experiment, maintain excellent descriptions of experiments performed, standardize and validate new methods and be able to interpret results. Computer skills such as entering data obtained from experiments into graphic and statistics programs as well as the generation of figures are essentials. The employee should provide scientific expertise and organizational skills in getting involved in various research projects involving tissue and cell culture, small animal models and human subject research. Candidate with strong animal modeling background (GEMMs) is preferred and should be well-trained on animal biology. Candidate will be responsible for coordinating procedures with collaborators. Other skills include performing technical laboratory duties in accordance with general and/or specific plans. Read, write and edit manuscripts and reports, as well as help with grant writing.
Learning Objectives:
SCOPE: To coordinate and conduct experiments and design research projects in the areas of cell and molecular biology, and immunology in animal and human tissues. Will keep abreast with literature of interest to laboratory, write manuscripts and help with grant writing. Will confer with collaborators in Genitourinary Medical Oncology and translational and Human Subject research regarding new procedures and modify them according to the needs of the projects. Record and evaluate data obtained in accordance with methods. The
Eligibility Requirements:
REQUIREMENTS: Recent Ph.D. in immunology, cancer biology, molecular biology, genetics, or other related fields.
Mentor Matching:
This position reports to Jianjun Gao, M.D., Ph.D. See Dr. Gao's research profile.
Req #: 600655-202110221414
Job Title: Postdoctoral Fellow
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A postdoctoral positions on intravital microscopy of cancer invasion and metastasis is available in the laboratory of Peter Friedl, MD, PhD, in the Department of Genitourinary Medical Oncology of the UT MD Anderson Cancer Center. We are looking for highly self-motivated candidates with a recent PhD or MD/PhD degree, to investigate the mechanisms underlying the mechanical stress response during invasion and metastasis, as well as development of novel interventions to prevent both metastasis and reduce the cancer cells' ability to survive the stresses encountered during the metastatic journey.
Successful candidate must be able to design novel projects, create hypothesis-driven experiment, maintain excellent descriptions of experiments performed, standardize and validate new methods and be able to interpret results. Computer skills such as entering data obtained from experiments into graphic and statistics programs as well as the generation of figures after image analysis are essentials. The employee should provide scientific expertise and organizational skills in getting involved in various research projects involving tissue and cell culture, small animal models and human subject research. Candidate will be responsible for coordinating procedures with collaborators. Other skills include performing technical laboratory duties in accordance with general and/or specific plans. Read, write and edit manuscripts and reports, as well as help with grant writing.
Learning Objectives:
The candidate will learn the basics of metastatic organ colonization in vivo in the present of different challenges. The goal of the training is to be proficient in cell migration and live-cell / 3D microscopy, intravital microscopy, intersection of in vivo cell biology, quantitative image analysis and mathematical modeling, and RNA profiling of in vivo tissue samples. The candidate is required to have knowledge of cancer biology, confocal microscopy and image analysis.
Eligibility Requirements:
Recent Ph.D. in immunology, cancer biology, molecular biology, genetics, or other related fields. Prefer a candidate that has knowledge of cancer biology, confocal microscopy and image analysis.
Program Dates:
11/01/2022 - 10/31/2024
Mentor Matching:
This position reports to Peter Friedl, M.D., Ph.D. See Dr. Friedl's research profile.
Genomic Medicine
Req #: 600138-202107181140
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on lymphoma and CAR T single cell profiling projects. Our primary research focus areas are: to apply innovative bioinformatics approaches to better understand CAR T cell biology, resistance mechanisms to CAR T therapy, and the cellular & functional heterogeneity and evolutionary dynamics of cells within the tumor immune microenviroment (TME).
Learning Objectives:
The Postdoctoral Fellow will carry out integrative analysis of the multi-platform single cell sequencing (RNA/TCR/BCR/ATAC), cfDNA sequencing, and immunogenomic datasets generated on biopsies and therapeutic CAR T products from patients and patient-derived xenograft models, to comprehensively characterize the tumor ecosystem and identify predictive/prognostic signatures/biomarkers and potential targets that could be harnessed to design rational therapeutic interventions. The Postdoctoral Fellow will have great opportunities to collaborate with diverse groups of physician scientists, laboratory scientists and computational biologists at MD Anderson Cancer Center and will be co-mentored by Drs. Linghua Wang and Michael Green.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Linghua Wang, Ph.D. and is co-mentored by Michael Green, Ph.D., in Department of Lymphoma and Myeloma
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Wang (Lwang22@mdanderson.org) and Dr. Green (MGreen5@mdanderson.org) with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
Req #: 600138-202107181120
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on projects in the functional cancer epigenomics field utilizing CRISPR-based high-throughput screening approaches at bulk and single cell level. The primary research focus of the Rai lab is to determine epigenome reprogramming during cancer progression and resistance to immunotherapy, and to identify non-coding elements that can be targeted for therapeutics using novel modalities. Dr. Rai and team have published a number of studies in this field in top journals including Cell, Cancer Discovery, Cancer Cell, Nature Communications and Cell Reports.
Learning Objectives:
Postdoctoral Fellow will develop and apply novel CRISPR based tools at bulk and single cell level for identification of functional non-coding elements in the immune cells for immunotherapies. They will learn to devise hypothesis, design experimental plans and execute the strategy in wet and dry lab settings to perform cutting-edge science. The lab presents opportunities to gain expertise in epigenomic methods, molecular biology techniques, animal modeling of cancer as well as computational biology. They will also gain experience in grant writing and training junior scientists/students.
Eligibility Requirements:
Individuals with a PhD degree in any discipline of biology.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Kunal Rai, Ph.D. See Dr. Rai's research profile.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Rai at Krai@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202107181130
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on projects in the computational epigenomics field. Project will involve developing computational approaches for cutting-edge single cell epigenomic, CRISPR screening and genomic methods. The primary research focus of the Rai lab is to determine epigenome reprogramming during cancer progression and resistance to immunotherapy, and to identify non-coding elements that can be targeted for therapeutics using novel modalities. Dr. Rai and team have published a number of studies in this field in top journals including Cell, Cancer Discovery, Cancer Cell, Nature Communications and Cell Reports.
Learning Objectives:
Postdoctoral Fellow will develop and apply computational tools to gain insights from bulk and single cell epigenomic and genomic data, as well as developing tools for single cell functional epigenomics tools. They will learn to devise hypothesis, design experimental plans and execute the strategy to perform cutting-edge science. They will also gain experience in grant writing and training junior scientists/students.
Eligibility Requirements:
Individuals with a PhD degree in any discipline of biology.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Kunal Rai, Ph.D. See Dr. Rai's research profile.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Rai at Krai@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202107181110
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on the cancer single cell profiling projects. The primary research focus is: to apply innovative bioinformatics approaches to dissect tumor ecosystem and better understand tumor-immune co-evolution and therapy response. In particular, to profile in-depth the cellular & functional heterogeneity, lineage plasticity and evolutionary dynamics of tumor cells, and cells of the tumor immune microenvironment (TIME).
Learning Objectives:
Gain mechanistic understanding of tumor cell heterogeneity and immune resistance. Learn skills for immunogenomics and single cell sequencing data analysis, and cancer-specific bioinformatics. Learn study design, data analysis, interpretation, presentation, and manuscript writing.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Linghua Wang, Ph.D.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Linghua Wang at Lwang22@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202107181145
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work in Genomic Medicine Department on metabolic heterogeneity in pancreatic cancer. The primary research will focus on determining the molecular mechanisms responsible for mitochondrial functional diversity at the subclonal level and how metabolic heterogeneity affects tumor response to therapy.
Learning Objectives:
Focusing on pancreatic cancer the study will involve the use of multiple cutting-edge technologies such as genomic and RNA sequencing, single-cell transcriptomics, ATAC-seq, molecular barcoding, metabolomics and high content-imaging.
Eligibility Requirements:
Highly motivated individuals with a recent PhD degree in biological fields or MD/PhD. Experience preferred in metabolism, molecular biology and in vivo mouse work.
Program Dates:
The appointment is available effective April 1, 2021.
Mentor Matching:
This position reports to Andrea Viale, M.D. See Dr. Viale's profile.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Andrea Viale at aviale@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202107181150
Job Title: Postdoctoral Fellow
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We are seeking a talented and highly motivated Postdoctoral Fellow with computational and statistical background to work on immunogenomic profiling projects focusing on leukemias. Our goal is to apply innovative immunogenomics and bioinformatics approaches to better understand leukemogenesis, resistance mechanisms to chemo and immunotherapy, and deep profiling of the cellular & functional heterogeneity of leukemic cells, and the diverse cell populations within the tumor immune microenvironment. We will primarily be utilizing patient samples from leukemia clinical trials allowing us to interrogate translational questions that have immediate patient impact.
Learning Objectives:
Gain mechanistic understanding of tumor cell heterogeneity and immune resistance. Learn skills for immunogenomics and single cell sequencing data analysis, and cancer-specific bioinformatics. Learn study design, data analysis, interpretation, presentation, and manuscript writing. The Postdoctoral Fellow will carry out integrative analysis of the bulk and single cell sequencing (RNA/TCR/BCR/ATAC-seq), and immunogenomic datasets generated on clinical specimens from primarily patient samples on clinical trials, or animal models, to comprehensively characterize the tumor ecosystem and identify predictive/prognostic signatures/biomarkers and potential targets that could be harnessed to design rational therapeutic interventions. The Postdoctoral Fellow will have great opportunities to collaborate with diverse groups of physician scientists, laboratory scientists and computational biologists at MD Anderson Cancer Center and will be co-mentored by Dr. Hussein Abbas and Andy Futreal. Postdoc will have a primary appointment in Genomic Medicine Department with optional appointment in Department of Leukemia.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. However, we will provide guidance through navigating different areas of translational research. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Hussein Abbas, M.D., Ph.D., in Genomic Medicine and Leukemia Departments, and will be co-mentored by Andrew Futreal, Ph.D., Chair of Genomic Medicine.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Hussein Abbas (habbas@mdanderson.org) with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
Req #: 600138-202107181155
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on ovarian cancer immunogenomics studies. We are interested to conduct translational studies on clinical specimens collected from ovarian cancer patients to better understand the cellular and molecular underpinnings driving disease progression, therapy resistance, and minimal residual disease. We will apply innovative immunogenomics approaches such as multimodal single cell sequencing to characterize the cellular and phenotypic heterogeneity of tumor cells and the diverse cell populations within the tumor immune microenvironment and interactions among them, which we believe will generate a more complete picture of the tumor immune ecosystem and potential signatures, biomarkers, and targets for future clinical applications.
Learning Objectives:
Learn bioinformatics skills for processing and analyzing genomics and immunogenomics data, at bulk and single-cell levels; Better understand tumor cell heterogeneity and tumor immune microenviroment and their clinical significance; Improve skills in study design, data analysis, interpretation, presentation, and manuscript writing. The Postdoctoral Fellow will carry out integrative analysis of the bulk and single cell sequencing data generated on clinical specimens from ovarian cancer patients to comprehensively characterize the tumor ecosystem and identify predictive/prognostic signatures/biomarkers and potential targets that could be harnessed to design rational therapeutic interventions. The Postdoctoral Fellow will have great opportunities to collaborate with diverse groups of physician scientists, laboratory scientists, immunologists and computational biologists at MD Anderson Cancer Center and will be co-mentored by Drs. Linghua Wang and Amir Jazaeri.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Linghua Wang, Ph.D. and is co-mentored by Amir Jazaeri, M.D., in Department of Gynecologic Oncology and Reproductive Medicine.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Wang (Lwang22@mdanderson.org) and Dr. Jazaeri (AAJazaeri@mdanderson.org) with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202109220956
Job Title: Postdoctoral Fellow
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A Postdoctoral position is available in the Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Hussein A. Abbas, M.D., Ph.D., Assistant Professor in Department of Leukemia and Genomic Medicine.
The Postdoctoral Fellow will have great opportunities to collaborate with diverse groups of physician scientists, laboratory scientists and computational biologists at MD Anderson Cancer Center. The postdoc will have a primary appointment in Genomic Medicine Department with optional appointment in Department of Leukemia.
Learning Objectives:
We are seeking a talented and highly motivated Postdoctoral Fellow with computational background to work on readily available data from single cell sequencing platforms to conduct immunogenomic profiling focusing on leukemia. Our goal is to apply innovative immunogenomics and bioinformatics approaches to better understand leukemogenesis, resistance mechanisms to chemo and immunotherapy, and deep profiling of the cellular & functional heterogeneity of leukemic cells, and the diverse cell populations within the tumor immune microenvironment. We will primarily be utilizing patient samples from leukemia clinical trials allowing us to interrogate translational questions that have immediate patient impact. We will provide a nurturing environment to guide and mentor trainees throughout their training to navigate these different areas.
Eligibility Requirements:
Individuals with a PhD and a background in computational biology, bioinformatics, data science or a related field are encouraged to apply. Background in computational biology, proficiency in programming (e.g. R, Python etc), familiarity and working with high-performance computing and biologic sciences are preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Hussein A. Abbas, M.D., Ph.D.
Additional Application Information:
Consideration of applications will begin immediately and continue until the position is filled.
Dr. Abbas is a tenure-track assistant professor in Department of Leukemia and Genomic Medicine at M D Anderson Cancer Center. He is a physician scientist with background in clinical medicine, computational and bioinformatics and laboratory biology focusing on leukemia. Our recent work (Abbas et al Nat Comms (2021), Abbas et al Blood Adv (2021), Abbas et al Front Onc (2021) & Abbas et al Front Imm (2021)) demonstrated the plasticity of the T cell compartment in leukemias, the complex interaction of AML cells with their environment, and the distinct metabolic states of AML. Building on these findings, our lab is interested in further understanding the mechanisms of resistance of leukemia to chemo and immunotherapy that can guide management of leukemia patients and improving their outcomes. We are leveraging high-throughput tools such as scRNA, scATAC, scTCR, scBCR, among others in patients on clinical trials to address these questions.
Req #: 600138-202109301415
Job Title: Postdoctoral Fellow
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We are looking for a post-doctoral fellow that is seeking training in translational research at the interface of oncology, immunology and the microbiome. Our usual project begins with studying cancer patient biospecimens, utilizing immune, microbiome and metabolomic analyses to evaluate for associations with key clinical outcomes. We then test hypotheses that arise using in vitro and preclinical mouse models. The overriding goals are: 1) achieving a better understanding of how the microbiome and the immune system interact to impact on cancer patient outcomes, and 2) developing novel strategies to improve cancer patient outcomes.
Learning Objectives:
Gain experience with exploring human biospecimen data sets and testing resulting hypotheses experimentally. Learn skills for microbiome data analysis. Gain further experience in study design, data analysis, interpretation, presentation, and manuscript writing.
Eligibility Requirements:
Individuals with an MD or PhD degree. To be considered, candidates must have a strong background in human immunology or mouse immunology and have prior first-author publication(s). English fluency is required. Proficiency in R is highly valued as well as prior experience with the analysis of high-feature data (could be microbiome, RNA sequencing, etc.)
Program Dates:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Robert R Jenq, M.D. View Dr. Jenq's research profile.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae, manuscript PDFs, and the contact information of two to three (2-3) Referees to Dr. Robert Jenq with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
Consideration of applications will begin immediately and continue until the position is filled.
Req #: 600138-202109301415
Job Title: Postdoctoral Fellow
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We seek a talented and highly motivated Postdoctoral Fellow to work on the cancer chromatin organization and single cell profiling projects. The primary research focus is: to apply innovative bioinformatics approaches to dissect tumor ecosystem and better understand chromatin organization and tumor-immune co-evolution under therapy response. In particular, to profile in-depth the cellular & functional heterogeneity, lineage plasticity and somatic mutations and evolutionary dynamics of tumor cells.
Learning Objectives:
Gain mechanistic understanding of mutational processes, tumor cell heterogeneity/evolution and immune resistance. Learn skills for cancer genomics and single cell sequencing data analysis. Learn study design, data analysis, interpretation, presentation, and manuscript writing.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in Python or R and knowledge in biostatistics are required. Experience working with single cell sequencing data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Kadir Akdemir, M.D. View Dr. Akdemir's research profile.
Additional Application Information:
This position reports to Dr. Kadir Caner Akdemir in Genomic Medicine Department. Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Kadir Akdemir at kcakedemir@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”. Consideration of applications will begin immediately and continue until the position is filled. Soft Funded (Start-up Funds)
Req #: 600138-202112150942
Job Title: Postdoctoral Fellow
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We seek multiple talented and highly motivated Postdoctoral Fellows with a strong background in bioinformatics and passion in exploring the heterogeneity and evolution of tumor cells and tumor microenvironment (TME) using the state-of-the-art single cell and spatial profiling approaches. The primary research focus is to apply innovative bioinformatics approaches to dissect the tumor "ecosystem" and profile in-depth the phenotypic and functional heterogeneity, lineage plasticity and evolutionary dynamics of tumor and TME cells and cellular interactions among them to better understand cancer development, progress and therapy response.
Learning Objectives:
Learn and master skills for in-depth profiling of single cell sequencing and spatial transcriptomics data; Learn and master skills for integrative analysis of high-dimensional bulk and single-cell multi-omics data; Gain rich knowledge in cancer biology, cancer genomics and immunogenomics, and cancer-specific bioinformatics; Develop skills in study design, data interpretation, presentation, and manuscript writing; Develop skills in networking, career planning, teaching, grant writing, and other professional development skills that can help prepare them for their further careers.
Eligibility Requirements:
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g. Python, Perl) and knowledge in biostatistics are required. Experience working with single cell sequencing data and high-performance computing environment is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required.
Program Dates:
The appointments are immediately available. Appointees are expected to work forty hours per week.
Mentor Matching:
This position reports to Linghua Wang, Ph.D.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Linghua Wang at Lwang22@mdanderson.org with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name.”
Gynecology Oncology & Reproductive Medicine
Req #: 600389-202111091821
Job Title: Postdoctoral Fellow
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The trainee will be responsible for carrying out experiments, recording and analyzing data, keeping a laboratory notebook/records according to lab policy, and attendance at routine lab meetings. Laboratory oriented - Projects will be lab-based involving tissue culture, extracellular vesicles, tumor microenvironment, molecular biology techniques, data analysis, figure design and preparation, as well as animal work. Work will be manuscript-focused and will build toward eventual high-quality publications.
Learning Objectives:
- Extracellular vesicles
- Biology
- Therapeutic applicability
- Molecular biology techniques (isolation, characterization)
- In vivo techniques (models, surgery, treatment)
- Tumor microenvironment
- Biology as it relates to extracellular vesicles and interplay between the two
- Study potential therapeutic interventions to take advantage of findings
- Molecular biology techniques (in vitro assays for growth, viability, drug sensitivity, etc.)
- In vivo techniques (models, surgery, treatment)
- Data analysis
- Large data-set mining
- Statistical considerations for in vitro and in vivo work
- Figure design and preparation
- Designing impactful figures
- Software and data techniques for preparing figures methodically
Eligibility Requirements:
Ph.D.
Mentor Matching:
This position reports to Anil Sood, M.D. View Dr. Sood's research profile.
Req #: 600389-202112281808
Job Title: Postdoctoral Fellow
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In 2017, the Department of Gynecologic Oncology and Reproductive Medicine established a new clinic specifically for rare gynecologic malignancies aimed to provide a centralized location for personalized care for patients with rare gynecologic malignancies. This Center, with experienced providers treating rare gynecologic tumors, will attract a large number of patients through both doctor-directed- and patient self-referrals from local, national, and international markets. Traditionally, the evolution of new treatments for patients with rare tumors is exceedingly slow due to difficulties accumulating experiences and conducting clinical trials.
The high volume of centralized patients will lead to expertise development and clinical trials performance that will quickly move treatment algorithms for these patients.
For most rare tumors, treatment decisions are driven by limited individual exposures, anecdotal experiences of our peers, and extrapolation from other disease sites. For that reason, when patients are seen by a variety of providers, they are likely to receive a wide range of treatment recommendations. By concentrating care into a single provider or small cadre of providers with both intra- and inter-center consultants, patients are more likely to receive standardized care leading to better outcomes. In addition, as individual providers become more experienced with specific rare tumors, they will be able to adjust care to incorporate their growing expertise to manage the rare tumor. This will lead to more consistent, thoughtful, and ultimately better care for patients. The information gained will, in many instances, be hypothesis-generating and serve as the impetus for the development of clinical trials.
Learning Objectives:
This position is designed to allow trainees to participate in the expansion of a large tumor registry of patients with rare tumors of the female reproductive system (ovary, uterus, cervix, vulva, and vagina), which catalogs information regarding their diagnosis, treatment course, surveillance and recurrence patterns, and disease outcomes. The trainee and the team will then be able to organize these data into meaningful information correlating disease characteristics and treatment patterns with disease outcomes. We believe our registry will expand existing knowledge about these rare diseases that are more generalizable than currently exists.
- Clinical research implementation skills
- Database development and maintenance
- Regulatory and institutional
- Data extraction from clinical, imaging, and pathology notes
- Interaction with patient to obtain informed consents, update medical information
- Data analysis and reporting
- Manuscript and abstract submissions
Eligibility Requirements:
M.D degree
Mentor Matching:
This position reports to Michael M. Frumovitz, M.D. View Dr. Frumovitz's research profile.
Head & Neck Surgery
Req #: 137100-202108241236
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the laboratory of Curtis R. Pickering in the Department of Head and Neck Surgery at the University of Texas, MD Anderson Cancer Center. The laboratory is focused on translational genomics of head and neck cancer. This position will work on a project studying the role of CREBBP/EP300 mutations in the response to radiotherapy. The project will involve cell and molecular biology techniques related to epigenetics and the DNA damage response. A larger variety of techniques may be utilized, including ChIPseq and genomics. Our primary model systems are cancer cell lines, but could also include mouse xenografts and human tissue samples.
Learning Objectives:
Improve our understanding for the role of CREBBP/EP300 mutations in radiation response. Learn new techniques and experimental approaches. Publish manuscripts in high quality journals. Give internal and external presentations of the work. Assist in writing grants related to the project.
Eligibility Requirements:
A Ph.D. with a strong background in cell and molecular biology and experience with mammalian cell culture is required. Experience with mice, epigenetics, and computational biology is a plus. Knowledge of DNA damage signaling and head and neck cancer is also desirable. Applicants must have a strong work ethic and self-motivation. They must also have excellent English communication skills and be open to collaborations both inside and outside our institution.
Program Dates:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Curtis Pickering, Ph.D. View Dr. Pickering's research profile.
Req #: 137100-202109271903
Job Title: Postdoctoral Fellow
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The Amit Lab, in the Department of Head and Neck Surgery at the University of Texas M.D. Anderson Cancer Center, is seeking to recruit creative and driven postdoctoral fellows interested in working at the intersection of neuroscience and cancer biology.A major goal of the lab is to advance the current understanding of the nervous system contribution to cancer. We established experimental models in neuroscience research to uncover novel mechanisms used by the nervous system to promote tumor initiation, progression, and metastasis.Successful applicants will be expected to develop and/or apply these models to address basic or clinical research questions within our areas of focus, including tumor differentiation and development, the cellular composition of the tumor microenvironment, and cell lineage relationships in malignant and normal tissues. Key results are further explored experimentally, both in our lab and through collaboration, with the ultimate goal of translating promising findings into the clinic.
Eligibility Requirements:
Ph.D. or M.D. and research experience in, Neuroscience, Immunology, Molecular Biology, or Cell Biology, or related field.
All applicants should enjoy thinking deeply and working independently but also enjoy collaborating in a dynamic, exciting, and friendly team environment.
Qualified individuals will demonstrate the potential for research as evidenced by their training and first-author peer-reviewed publications in relevant journals and should become competitive for national research fellowships.
We are looking for candidates in two general areas to support these research goals including neuroscience and cell biology.
Wet lab candidates with a strong background in cellular and molecular techniques in cancer biology, stem cell biology, or tumor immunology are required. Familiarity with basic bioinformatics analysis is required.
Previous experience in common programming languages (i.e., R or Python) and image analysis is desired.
Program Dates:
10/01/2021 - 10/01/2022
Mentor Matching:
This position reports to Moran Amit, M.D., Ph.D. View Dr. Amit's research profile.
Req #: 137100-202111300835
Job Title: Postdoctoral Fellow
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Molecular and clinical epidemiology and translational study on identification of new biomarkers for risk and outcome of head and neck cancers.
Learning Objectives:
Objective 1. In his/her first 3-4 months, trainee will learn basic study design, data collection, and data analysis of molecular epidemiology study of one of my projects on head and neck cancers. By the end of his/her training period, trainee will master following 1) case-control or case-case study design, 2) development of study database for collected data and methods for new biomarkers, and 3) use statistical tools, such as SAS program, for data analysis.
Objective 2. Trainee will learn to present his/her research results in our weekly lab meeting or national meeting. By the end of his/her training appointment, trainee will know how to make slides for research presentation and get experience for data presentation for his/her own research.
Objective 3. Trainee will to learn how to prepare the manuscripts for his/her research and expect that trainee will probably have 1 to 2 scientific papers to be published within his/her one- or two-year training.
Eligibility Requirements:
M.D. degree or Ph.D. in molecular and cellular biology, or genetics or biochemistry or related fields in medical, genetic or biological sciences
Mentor Matching:
This position reports to Guojun Li, M.D., Ph.D. View Dr. Li's research profile.
Health Disparities Research
Req #: 106500-202107181110
Job Title: Postdoctoral Fellow
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The postdoctoral scholar will primarily work with Dr. Qian Lu. On-going projects in the Lu lab include psychosocial interventions (expressive writing, social support, video and written narrative messages), cancer survivorship, HPV vaccination, community based participatory research, cultural and biopsychosocial determinants of health (social support, emotion regulation, stress biomarkers) and health disparities research. Our recent completed studies include psychosocial interventions among Chinese breast cancer survivors, biopsychosocial factors influencing adjustment, cross-culture comparisons between Caucasian and Asian cancer survivors on adjustment, and validation of questionnaires.
Learning Objectives:
- Work on NIH-funded projects to develop and test culturally sensitive psychosocial interventions (expressive writing intervention and peer mentoring/social support intervention) to improve the quality of life among Chinese immigrant cancer survivors.
- Contribute to the scientific aspects of the study, such as refining study design and materials, managing data, and assisting with project management.
- In coordination with the principal investigator, conduct secondary data analyses and lead the research team in writing manuscripts.
- Learn how to write grant proposals.
Eligibility Requirements:
Applicants should send a cover letter stating research interests and experience, curriculum vitae, a list of two references, and up to two first-author reprint/writing sample(s) to Qian Lu, PhD., M.D. at (qlu at mdanderson.org) with the subject line "Postdoctoral Scholar Application".
Candidates with a doctorate who are well trained in psychology, public health, or health, or other behavioral science are welcome.
It is desirable that candidates are bilingual (English and Chinese).
Dates or Training Schedule:
June 15, 2021- June 14, 2022
Mentor Matching:
This position reports to Qian Lu, M.D., Ph.D.
Additional Application Information:
This fellowship is a one- to two-year, full-time commitment, renewable upon mutual consent with competitive salary and benefits. Opportunities for the fellow to write and submit his/her individual grant (e.g. NIH career development award) would be provided and strongly supported by the PI and the institution.
Req #: 106500-202107181120
Job Title: Postdoctoral Fellow
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We are seeking talented, disciplined, and motivated postdoctoral fellows with training and experience in one or more of the following: behavioral science, social science, psychology, and/or health services research, and a track record of peer-reviewed publications.
The position is at The University of Texas MD Anderson Cancer Center in the Health Disparities Research Department (HDR) of the Division of Cancer Prevention & Population Sciences in Houston, TX. HDR supports a portfolio of investigator-initiated grants, and develops funding opportunities and research resources to reduce, and ultimately eliminate, disparities in cancer incidence, morbidity and mortality and cancer-related behavior through research and education addressing the determinants of disparities as well as interventions and policies designed to eliminate disparities.
The postdoctoral candidate will focus on assisting our team to build upon an existing research partnership with Hispanic and African American churches in Houston. He/She will actively participate in ongoing NIH and ACS-funded studies that seek to use community-based approaches to test the feasibility and acceptability of two obesity interventions for Hispanic and African American families—one focused on the parent (i.e., Parent Intervention) and the other focused on the entire family (i.e., Family Intervention).
Learning Objectives:
- Planning, organizing, coordinating and participating in scientific research projects.
- Work closely with Research Manager to manage personnel tasks.
- Work closely with Department Chair to determine specific goals or objectives to be obtained for each research project and evaluate research data, develop, and revise techniques or approaches to work problems.
- Develop and/or recommend program intervention, prevention, and/or control strategies.
- Provide expertise and services on behavioral research-related issues, data management, analysis, and interpretation.
- Provide experience-based recommendations and research direction as requested on other studies conducted by, or on the behalf of, the Department Chair.
- Conduct research activities (extensive literature reviews) and edit reports, presentations, and other documents.
- Present findings of research projects to professional groups and prepare scientific documents for publication.
Eligibility Requirements:
- Ph.D. in psychology, public health or other related behavioral/social sciences discipline; or is currently enrolled in a doctoral degree program and will have fulfilled all degree requirements prior to beginning the postdoctoral fellowship
- Knowledge and experience with cancer research
- Be able to function in a separate and independent manner in the design and initiation of research experiments
- Strong data analysis skills
- Excellent oral presentation and writing skills
- Advanced training in research methodology and strong publication record
- Strong work ethic and commitment to becoming an independent scientist
- A defined research focus including (but not limited to) obesity and physical activity;
- Established record of scholarly research, including extramural funding
Dates or Training Schedule:
09/01/21-09/01/22
Mentor Matching:
This position reports to Lorna H. McNeill., Ph.D. View Dr. McNeill's research profile.
Additional Application Information:
- Letter describing areas of research interest
- Curriculum vitae with bibliography
- Copies of 1-2 recent publications
- 3 letters of recommendation
Health Services Research
Req #: 600119-202108161836
Job Title: Postdoctoral Fellow
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Under the mentorship of Dr. Iakovos Toumazis, this postdoctoral fellowship will provide individuals with the opportunity to contribute to the design, implementation, analysis, and publication of studies focusing on health policy analytics and modeling. The position focuses on the development and application of computer simulation-based modeling to simulate the disease progression of specific cancers (e.g. lung cancer, ovarian cancer), assess the impact of alternative primary, secondary and tertiary prevention strategies on cancer incidence and mortality rates in the US population, and inform public health policy.
Job Responsibilities:
· Develop simulation models for decision analysis, cost-effectiveness analysis, and value of information analysis.
· Develop risk prediction models using advanced analytic methods.
· Work with the research team on development of decision aid tools.
· In coordination with the principal investigator, lead the research team in writing manuscripts and grant applications.
Eligibility Requirements:
Expertise in stochastic simulation modeling, Monte Carlo methods, model validation and calibration.
Experience in survival analysis, parameter estimation, data analytics, and applications of operations research to public health and medical decision making is highly desired.
Good understanding of mathematical modeling and hands-on experience of general-purpose programming languages such as R, Python, Julia, or MATLAB.
Strong writing and verbal communication skills are required.
Education:
Qualified candidates should have a Doctorate Degree in industrial engineering, operations research, computer science, health services research, epidemiology, health-outcomes research, biostatistics or a related quantitative field.
Mentor Matching:
This position reports to Iakovos Toumazis, Ph.D.
Additional Application Information:
This fellowship is a one-year, full-time commitment, renewable upon mutual consent with competitive salary and benefits. Opportunities for the fellow to write and submit his/her individual grant (e.g. NIH career development award) would be provided and strongly supported by the PI and the institution.
To apply, interested candidates should submit a brief cover letter personalizing one's interest in the position, with information about research experience and interests, and their CV with the names and contact information for references to Dr. Iakovos Toumazis, IToumazis@mdanderson.org with subject: ”Postdoctoral Fellowship Application.” Review of applications will begin immediately and continue until the position is filled.
Req #: 600119-202112150938
Job Title: Postdoctoral Fellow
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The Department of Health Services Research at The University of Texas MD Anderson Cancer Center has an opening for a postdoctoral fellowship. Under the mentorship of Dr. Iakovos Toumazis, this postdoctoral fellowship will provide highly motivated individuals with the opportunity to contribute to the design, implementation, analysis, and publication of studies focusing on public health policy and simulation modeling. The position focuses on the development and application of computer simulation-based modeling to simulate the natural disease progression of lung cancer and evaluate the impact of alternative cancer interventions on cancer incidence and mortality rates in the US population.
Job Responsibilities:
Qualified candidates will be expected to develop microsimulation models for decision analysis and cost-effectiveness analysis. Prepare scientific manuscripts and presentations for scientific meetings. In coordination with the principal investigator, lead the research team in writing manuscripts, disseminating findings at scientific meetings, and preparing grant applications. Opportunities for the fellow to write and submit his/her individual grant (e.g. NIH career development award) would be provided and strongly supported by the PI and the institution.
Qualifications:
Expertise in stochastic simulation modeling and Monte Carlo methods.
Experience with model validation and calibration is highly desired but not required.
Some experience in survival analysis, parameter estimation, and data analytics is desired.
Good understanding of mathematical modeling and hands-on experience of general-purpose programming languages such as R, Python, Julia, or MATLAB.
Strong writing and verbal communication skills are required.
Eligibility Requirements:
Qualified candidates should have a Doctorate Degree in industrial engineering, operations research, computer science, health services research, epidemiology, health-outcomes research, biostatistics, data sciences or a related quantitative field.
Program Dates:
The fellowship is a one-year, full-time commitment, renewable upon mutual consent.
Mentor Matching:
This position reports to Iakovos Toumazis, Ph.D.
Additional Application Information:
To apply, interested candidates should submit a brief cover letter personalizing one’s interest in the position, with information about research experience and interests, and their CV with the names and contact information for references to Dr. Iakovos Toumazis, with subject: ”Postdoctoral Fellowship Application – Microsimulation.” Review of applications will begin immediately and continue until the position is filled.
Req #: 600119-202112150924
Job Title: Postdoctoral Fellow
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The Department of Health Services Research at The University of Texas MD Anderson Cancer Center has an opening for a postdoctoral fellowship. Under the mentorship of Dr. Iakovos Toumazis, this postdoctoral fellowship will provide highly motivated individuals with the opportunity to contribute to the design, implementation, analysis, and publication of high-impact studies focusing on optimizing public health policy analytics and decision analytic modeling. The position focuses on the development and application of dynamic optimization programs for sequential decision making under uncertainty, and their implementation to assess the effectiveness and cost-effectiveness of the derived optimal policies on lung cancer incidence and mortality rates in the US population.
Job Responsibilities:
Qualified candidates will be expected to develop optimization models to optimize sequential medical decision making under uncertainty for lung cancer screening. Apply the optimization model to assess the effectiveness and cost-effectiveness of the interventions of interest using simulation modeling and inform public health policy. In coordination with the principal investigator, lead the research team in writing manuscripts, disseminating findings at scientific meetings, and preparing grant applications. Opportunities for the fellow to write and submit his/her individual grant (e.g. NIH career development award) would be provided and strongly supported by the PI and the institution.
Qualifications:
Expertise in Markov decision process (MDP), partially observable Markov decision process (POMDP) and dynamic programming is required.
Experience in simulation modeling, data modeling under uncertainty and applications of operations research to public health and medical decision making is highly desired but not required.
Good understanding of mathematical modeling and hands-on experience of general-purpose programming languages such as R, Python, Julia, or MATLAB.
Strong writing and verbal communication skills are required.
Eligibility Requirements:
Qualified candidates should have a Doctorate Degree in industrial engineering, operations research, computer science, health services research, epidemiology, health-outcomes research, biostatistics or a related quantitative field.
Program Dates:
The fellowship is a one-year, full-time commitment, renewable upon mutual consent.
Mentor Matching:
This position reports to Iakovos Toumazis, Ph.D.
Additional Application Information:
To apply, interested candidates should submit a brief cover letter personalizing one’s interest in the position, with information about research experience and interests, and their CV with the names and contact information for references to Dr. Iakovos Toumazis, with subject: ”Postdoctoral Fellowship Application. Review of applications will begin immediately and continue.” Review of applications will begin immediately and continue until the position is filled.until the position is filled.
HematoPathology
No positions are currently available in this department. Check back later for new opportunities.
Hematopoietic Biology and Malignancy
Req #: 710597-202109091703
Job Title: Postdoctoral Fellow
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A Postdoctoral position is available in the Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Pavan Bachireddy in the Department of Hematopoietic Biology and Malignancy.
Learning Objectives:
We are seeking a talented and highly motivated Postdoctoral Fellow interested in understanding the co-evolutionary interactions between cancer and immune cells in the tumor microenvironment. Our lab uses unbiased, high-throughput technologies to decode the rules of interaction among diverse cell types in the tumor milieu that determine patient outcomes to cancer immunotherapy, primarily in hematologic malignancies. In vitro and in vivo functional genomic screens are critical approaches to validate and extend our findings.
Dr. Bachireddy is also deeply committed to the career growth and success for each member of the laboratory. Such mentorship should be intentional, planned and tailored to each member of the group – thus the laboratory operates with a primary goal of fostering career goals and development.
The fellow will lead work focused on 1) interrogation of factors reversing immune dysfunction and 2) identification of molecular and cellular determinants of successful graft-versus-leukemia outcomes, using multiple cutting-edge technologies as well as standard cell culture and immunologic approaches. Because Dr. Bachireddy is the Scientific Director of the ECLIPSE (Evolution of Cancer, Leukemia and Immunity Post Stem cEll transplant) platform, the fellow will have significant interaction and access to the vast immunogenomic and computational resources of the physically adjacent ECLIPSE platform.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
Eligibility Requirements:
Individuals with a PhD degree in cancer biology, molecular biology, genetics, immunology, or related fields with less than 2 years of postdoctoral experience. Experiences that are desirable (but not required) include: CRISPR, next-gen sequencing (bulk or single cell genomics), or animal modeling. Candidate should have a background in immunology and the ability to prioritize and manage multiple projects. Proven track record of publications, excellent written and oral communication skills are required.
Dates or Training Schedule:
December 7, 2021 - December 6, 2022
Mentor Matching:
This position reports to Pavan Bachireddy, Ph.D. View Dr. Bachireddy's research profile.
Req #: 710597-202111051243
Job Title: Postdoctoral Fellow
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A Postdoctoral position in Computational Immunology is available in the Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Shukla in the Department of Hematopoietic Biology and Malignancy and Department of Immunology.
Learning Objectives:
The Shukla lab is a highly translational group focused on antigen discovery and development of personalized immunotherapies. We build computational approaches and harness state-of-the-art technologies and experimental assays to elucidate mechanisms underlying immunogenicity, immune escape and clinical outcomes to cancer immunotherapy.
We are currently recruiting a highly motivated Postdoctoral Fellow with a strong computational background and a deep desire to address critical bottlenecks in cancer immunotherapy through methodological innovation. The fellow will develop novel tools for characterization, somatic variation detection and quantification of key genetic elements in the cancer-immunity cycle through analysis of data from bulk and single-cell sequencing platforms. While the primary focus will be algorithmic advancement, the fellow will also work with software engineers in order to produce well-documented, version-controlled and user-friendly software. The fellow will work closely with experimental collaborators in the department to iteratively improve and validate the newly developed methods. The candidate will play a key role in deploying these tools in high-impact research and clinical settings across the institute.
Dr. Shukla is deeply committed to the professional fulfillment and career advancement of all trainees. He will work on creating a successful transition plan to either academia or industry in accordance with the fellow's evolving preferences. The fellow will have access to computational and immunological platforms, expertise and mentoring advice from researchers in the ECLIPSE Moon Shot Research platform where Dr. Shukla will serve as the Computational Director. The candidate will also benefit from collaborations with Broad Institute members with a strong track record in creating widely used tools for cancer genome analysis.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
Eligibility Requirements:
Individuals with a PhD degree in Computational Biology, Bioinformatics, Statistics, Computer Science, Computer Engineering, Physics or related fields. The ideal candidate will have a solid knowledge of genomic sequence analysis methods such as de Bruijn graphs, suffix arrays, contig assembly, mutation and copy number detection. A proven track record in developing computational biology tools is required. Experience with implementing at least one sequencing-based method is highly desirable. Prior background in single-cell analysis is helpful but not required. A knowledge of object-oriented programming concepts is expected. Knowledge of immunology is preferable. Proven track record of publications, excellent written and oral communication skills are required. Partial or fully remote work options can be considered for exceptional applicants.
Dates or Training Schedule:
January 4, 2022 - January 3, 2023
Mentor Matching:
This position reports to Dr. Sachet Shukla.
Additional Application Information:
Consideration of applications will begin immediately and continue until the position is filled.
Req #: 710597-202112071635
Job Title: Postdoctoral Fellow
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A Postdoctoral position is available in the Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Deepa Sampath in the Department of Hematopoietic Biology and Malignancy.
Learning Objectives:
We are seeking a talented and highly motivated Postdoctoral Fellow to perform hands-on experiments to generate CRISPR edited lines and perform basic and translational research to investigate the genetic and epigenetic mechaisms underlying the formation and growth of hematological malignancies. The Postdoctoral Fellow will conduct experiments to measure gene expression, chromatin conformation, single cell RNA and ATAC sequencing as well as synthetic lethal studies in cultured cells and primary tissue. The fellow will also be involved in study design, data analysis and manuscript preparation by attending lab meetings, journal clubs, and research seminars.
The Postdoctoral Fellow's primary research focus is to gain mechanistic understanding of genetic and epigenetic mechanisms that drive hematological malignancies; learn molecular biology and genomics analysis skills and train and learn study design, data analysis and manuscript writing.
Eligibility Requirements:
Individuals with a PhD degree in cancer biology, molecular biology, genetics, immunology, or related fields with less than 2 years of postdoctoral experience. Experience with rodent studies is required for this role. Candidate should have strong organizational skills and the ability to prioritize and manage multiple projects. Proven track record of publications, excellent written and oral communication skills are required.
Dates or Training Schedule:
February 15, 2022 - February 14, 2023
Mentor Matching:
This position reports to Deepa Sampath, Ph.D.
Additional Application Information:
Consideration of applications will begin immediately and continue until the position is filled.
Imaging Physics
Req #: 600651-202107181120
Job Title: Postdoctoral Fellow
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We are looking for several postdoctoral researchers in the areas of medical image analysis and translational cancer research to join a newly established research lab.
Learning Objectives:
The research themes are center on 1) develop innovative quantitative imaging biomarkers to characterize cancer phenotypes; 2) integrate image with multi-omics data across multiple scales to decipher cancer mechanisms; 3) validate and translate imaging biomarkers to guide clinical practice.
Eligibility Requirements:
Candidates from a diverse background are encouraged to apply. The successful applicant must have a Ph.D. in the fields of Biomedical Engineering, Applied Mathematics,Computer Science, Electronic Engineering, Bioinformatics, or related fields.
Dates or Training Schedule:
8/15/2020-8/14/2021
Mentor Matching:
This position reports to Jia Wu, Ph.D.
Req #: 600651-202107181110
Job Title: Postdoctoral Fellow
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A postdoctoral fellowship position is available in the Department of Imaging Physics in the laboratory of Kristy Brock, Ph.D. The Morfeus Lab at MD Anderson ( https://www.mdanderson.org/research/departments-labs-institutes/labs/morfeus-laboratory.html) is led by Dr. Kristy Brock. Our research is focused on development of deformable image registration, artificial intelligence (AI), biomechanical modeling, and image guided cancer therapy technologies for strategic research collaboration and deployment into the clinical setting. Our lab is a highly collaborative research training environment in a state-of-the-art imaging facility and world class resources. Ongoing projects seeking postdocs include:
1) Image-guided liver surgery
2) Image-guided head and neck surgery
3) Cancer risk assessment and outcomes prediction using artificial intelligence
4) Validating in vivo imaging signals using correlative pathology
5) Image-guided focal liver ablation
6) Dose accumulation for personalized adaptive radiation therapy
Learning Objectives:
This postdoctoral fellow will engage in computational research projects in image guided cancer therapy including research, design, and implementation of deformable image registration, biomechanical modeling, and artificial intelligence technologies. The fellow will expand their knowledge and skills in imaging physics, data mining, predictive modeling, clustering, and classification and will develop, train, and apply deep learning in large data environments. The fellow will help to guide research and clinical collaborations and work with collaborators to integrate image guided cancer therapy models and technologies into the clinical workflow. They will collaborate and coordinate with research and clinical stakeholders, communicate findings via abstracts, poster and podium presentations, and publications.
Eligibility Requirements:
Applicants should have earned a Ph.D. in one of the natural sciences, computer sciences, engineering, or related fields or a medical degree. Experience with machine learning and deep learning techniques, statistical modeling, biomechanical modeling, or image registration and analysis is preferred.
Mentor Matching:
This position reports to Kristy Brock, Ph.D.
Req #: 600651-202107181140
Job Title: Postdoctoral Fellow
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Postdoctoral training that will consist of carrying out an independent research in the area of molecular photoacoustic imaging of ovarian and breast cancers using antibody-targeted liposome encapsulated J-aggregates of ICG dye molecules.
Learning Objectives:
Principles of photoacoustic imaging in vivo that will include instrumentation, fluence correction and spectral unmixing algorithms. In addition, there will be training in scientific writing through submission of peer reviewed manuscripts.
Eligibility Requirements:
Ph.D. in Bioengineering is preferred. Ph.D. in other natural science disciplines will be considered.
Program Dates:
August 1, 2021 thru July 31, 2022
Mentor Matching:
This position reports to Konstanin Sokolov, Ph.D. See Dr. Sokolov's research profile.
Req #: 600651-202109030945
Job Title: Postdoctoral Fellow
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A postdoctoral fellowship is available in the Department of Imaging Physics in the laboratory of S. Cheenu Kappadath, Ph.D. Our research is focused on advancing quantitative imaging and dosimetry in theragnostic and clinical nuclear medicine (SPECT/CT and PET/CT) by applying physics, engineering and mathematics to improve the quantitative accuracy. Ongoing research projects include: (1) Quantification of absorbed doses and dosimetry for 90Y-microsphere radioembolization therapies, (2) Image quantification for theragnostic and radionuclide therapies, (3) Optimization of SPECT/CT and PET/CT image generation, and (4) Quantification and response assessments with molecular breast images (MBI). Postdoctoral training will consist of carrying out supervised and independent research and collaborating with a multi-disciplinary team comprising of interventional radiologists, NM physicians, medical oncologist, and physicists.
Learning Objectives:
The fellow will expand their knowledge and skills in nuclear medicine physics, image reconstruction, image quantification, data mining, predictive modeling, and will develop, train, and apply deep learning in large data environments. The fellow will participate and help to guide research and clinical collaborations and work with collaborators on funded projects and clinical trials. They will collaborate and coordinate with research and clinical stakeholders, communicate findings via abstracts, poster and podium presentations, and publications. The individual, under the supervision of a faculty mentor, will be prepared for an academic medical physicist career as an independent investigator.
Eligibility Requirements:
Applicants should have earned a Ph.D. in physics, computer sciences, engineering, or related fields. Experience with radioembolization, Monte Carlo simulations, machine learning, statistical modeling, and analysis is desired.
Program Dates:
January 1, 2022 through December 31, 2023
Mentor Matching:
This position reports to S. Cheenu Kappadath, Ph.D. See Dr. Kappadath's research profile.
Additional Application Information:
Additional information or requirements specific to the position or program, i.e., additional documents, program requirements, URL link to the department/program website, featured videos, etc.
Immunology
Req #: 206100-202107181130
Job Title: Postdoctoral Fellow
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Postdoctoral position at the nexus of immunology and neurology available in the lab of Dr. Michael A. Curran at the University of Texas MD Anderson Cancer Center. Dr. Curran was the first to study and report the combination of CTLA-4 and PD-1 blockade which remains the most effective clinical immunotherapy. The Curran lab studies mechanisms of immune resistance in "cold" cancers (prostate, pancreatic, glioblastoma), in particular focused on tumor hypoxia and oxygen metabolism, as well as on novel approaches to modulation of the tumor myeloid stroma. Application of this knowledge to addressing underlying causes of neurodegeneration in models of Alzheimer's disease has become a new focus within the lab. We have achieved success pursuing a novel immune therapy focused on removal of neurotoxic aggregates from the CNS. This work is funded by both a philanthropic award and grant, as well as by a dedicated NIH grant. Prior fellows hold tenured academic professorships, scientist positions in industry, and senior positions in patient-focused immune monitoring centers.
Learning Objectives:
Successful candidates will lead a project to develop a myeloid-based adoptive cell therapy for the treatment of neurodegenerative disease.
Eligibility Requirements:
Candidates must have a recent Ph.D. degree in a related field along with lead-author publications, excellent communication skills, and the ability to work independently within a research team. Candidates who pursue an independent career path are highly preferred. Expertise in immunology, neurology/neurodegeneration, and/or viral vector based cell engineering is also desirable.
Mentor Matching:
This position reports to Michael Curran, Ph.D. See Dr. Curran's research profile.
Req #: 206100-202107181140
Job Title: Postdoctoral Fellow
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Postdoctoral position in basic and translational immune checkpoint biology and immunotherapy available in the lab of Dr. Michael A. Curran at the University of Texas MD Anderson Cancer Center. Dr. Curran was the first to study and report the combination of CTLA-4 and PD-1 blockade which remains the most effective clinical immunotherapy. The Curran lab studies mechanisms of immune resistance in "cold" cancers (prostate, pancreatic, glioblastoma), in particular focused on tumor hypoxia and oxygen metabolism, as well as on novel approaches to modulation of the tumor myeloid stroma. Research in the lab spans basic T cell co-stimulatory biology, tumor microenvironment studies in murine models, and ongoing clinical trials and associated correlatives. The lab offers unique resources for research in mice and in man, as we have developed our own novel immune checkpoint antibodies and uniquely potent agonists of the Stimulator of Interferon Genes (STING) innate immune sensor. Prior fellows hold tenured academic professorships, scientist positions in industry, and senior positions in patient-focused immune monitoring centers.
Learning Objectives:
Successful candidates will lead a project to integrate modulation of cold tumor metabolism and T cell / myeloid stroma to foster immune rejection of “cold” cancers.
Eligibility Requirements:
Candidates must have a recent Ph.D. degree in a related field along with lead-author publications, excellent communication skills, and the ability to work independently within a research team. Candidates who pursue an independent career path are highly preferred. Expertise in cancer immunology, murine tumor modeling, and/or tumor/immune metabolism is also desirable. Specific interest in immunobiology of glioblastoma and its immune microenvironment is a plus.
Mentor Matching:
This position reports to Michael Curran, Ph.D. See Dr. Curran's research profile.
Req #: 206100-202107181150
Job Title: Postdoctoral Fellow
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The mission of our lab is to investigate the mechanisms that regulate T cell destabilization and infiltration in cancer. Specifically, we want to understand how antigen-presenting cells control Treg reprogramming and accumulation within the tumor microenvironment. Our final goal is to develop new strategies for patients that do not respond to current cancer immunotherapies.
Learning Objectives:
By combining genetic mouse models and analyses of human cancer samples, the successful candidates are expected to identify which key signals are necessary for intratumoral Treg instability and expansion in order to finally provide new individualized immunotherapy approaches to patients.
Eligibility Requirements:
Ph.D. in life or physical sciences (examples: immunology, biology, bioinformatics, physics)
Record of successful first author publications
Expertise in flow-cytometry and/or analysis of high-dimensional biological datasets
Experience in mouse models, single cell genomics, molecular cloning and microscopy
Mentor Matching:
This position reports to Mauro Di Pilato, Ph.D.
Additional Application Information:
Two postdoctoral training positions are available in the laboratory of Mauro Di Pilato in the Department of Immunology at The University of Texas MD Anderson Cancer Center.
Req #: 206100-202107181155
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the laboratory of Dr. Shao-Cong Sun to study the molecular mechanisms that regulate anti-tumor immunity and autoimmune diseases. The focus of our research is on characterizing novel regulators of T cell activation, metabolic reprogramming, and effector functions in mouse models of anti-tumor immunity and autoimmune diseases. In addition, we are studying the signaling network in innate immune cells (dendritic cells and macrophages) that regulate inflammation, tumor microenvironment, and T cell functions. For more information, please check our recent publications in the website http://faculty.mdanderson.org/Shao-Cong_Sun/.
Learning Objectives:
Successful candidates will join a collegial and highly interactive team and enjoy the stimulating environment of UT MD Anderson Cancer Center. The Department of Immunology, led by Nobel Laureate James Allison, conducts cutting-edge research in different areas of Immunology. Dr. Sun's laboratory has a long history of success in research and postdoctoral training.
Eligibility Requirements:
Candidates should have a solid background in Immunology, with hand-on experience in flow cytometry, molecular techniques, and mouse models of anti-tumor immunity and/or autoimmune diseases.
Mentor Matching:
This position reports to Shao-Cong Sun, Ph.D. See Dr. Sun's research profile.
Req #: 206100-202110051445
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in Dr. James Allison's Immunology Laboratory. The focus of our research is on the fundamental mechanisms of T cell activation and regulation through cell surface receptors of the T cells and the antigen presenting cells with which they interact. The lab also investigates the mechanisms through which alterations in cell surface receptor signaling on multiple cell types affect the cancer immune response. This is an excellent opportunity for a highly self-motivated recent PhD recipient accustomed to working independently to explore fundamental biology that lies at the heart of immuno-oncology in a world-class environment.
Learning Objectives:
The successful candidate will contribute to a fast-paced and highly collaborative laboratory environment. The candidate will be expected to formulate, execute, and document an independent research project based on general guidelines set by the principal investigator. After a successful training period, the candidate will be prepared for a career as a competitive independent researcher.
Eligibility Requirements:
Candidates must have a recent Ph.D. in a related field and strong experience in mouse tumor models, flow cytometry, and immunology with a solid publication record. Experience in epigenetics, mass cytometry, or single-cell sequencing is a plus.
Mentor Matching:
This position reports to James P. Allison, Ph.D. See Dr. Allison's research profile.
Req #: 206100-202111300826
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in Department of Immunology at MD Anderson Cancer Center, Houston, TX. Our research is to understand the molecular basis of T cell mediated immune responses, and how abnormal immune regulation leads to immunodeficiency, autoimmunity and cancer. Autoimmunity and inflammation mouse models include experimental autoimmune encephalomyelitis (EAE), arthritis, colitis, and lung airway inflammation; tumor immunity models include T cell-mediated immune responses against transplanted melanoma, chemical induced sarcoma, and lung cancer.
Learning Objectives:
The Nurieva lab at the MD Anderson Cancer Center is recruiting a postdoc who will be expected to execute and document research in the following projects: (1) The molecular mechanisms of Tcell activation and tolerance; (2) The signaling and transcriptional mechanisms underlying T helper cell differentiation and function; and (3) The mechanisms underlying immune-related adverse events after immune checkpoint inhibitor therapy.
Eligibility Requirements:
Candidates should have a recent Ph.D. degree or in the process of completing Ph.D. training and a solid background in Immunology, with preferred hand-on experience in flow cytometry, molecular techniques, and mouse autoimmune and/or tumor models..
Mentor Matching:
This position reports to Roza Nurieva, Ph.D. See Dr. Nurieva's research profile.
Additional Application Information:
Send curriculum vitae and names of three references to: Dr. Roza Nurieva, e-mail: rnurieva@mdanderon.org.
Req #: 206100-202201241407
Job Title: Postdoctoral Fellow
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A postdoctoral position is available in Dr. Zhibin Zhang's Lab at Department of Immunology, UT MD Anderson Cancer Center. The immunology department, chaired by Nobel Prize Laureate Dr. James Allison, focus on various aspects of immunology, particularly cancer immunology. The mission of our lab is to fully understand the activation and regulation mechanisms of pyroptosis in tumor cells in order to develop novel therapeutic interventions to enhance anti-tumor immunity and treat tumor. For further details of our research, please refer to our recent publications (Nature 2016 PMC5539988; Nature 2020 PMC7123794; Cancer Immunol Res 2021 PMC7789047; Nat Rev Drug Discov 2021 PMC7944254).
Learning Objectives:
This position will focus on the role of pyroptosis in tumor immunology. The candidate will combine biochemical, molecular biological, cell biological, mouse genetic and systems biological tools to explore the activation and regulation of gasdermin proteins, the executors of pyroptosis, in the context of tumor-immune system interaction. Priority will be given to applicants with extensive experience in mouse tumor models and tumor immunology
Eligibility Requirements:
Applicants must have a recent Ph.D. degree or equivalent in related biomedical field with strong self-motivation.
Program Dates:
The appointment is immediately available.
Mentor Matching:
This position reports to Zhibin Zhang, Ph.D.
Additional Application Information:
Send curriculum vitae and names of three references to: Dr. Roza Nurieva, e-mail: rnurieva@mdanderon.org.
Infectious Diseases
Req #: 600702-202111300838
Job Title: Postdoctoral Fellow
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The Postdoctoral Fellow will contribute to the writing of scientific manuscripts, and conduction of studies pertaining to the following areas:
1. Device-related infections, biofilm and antimicrobial catheter locks.
2. Novel antimicrobial therapy .
3. Antimicrobial stewardship & biomarkers of infections ( e.g Procalcitonin).
4. COVID19 in cancer patients
The fellow will also participate in monitoring activities by ensuring conduction of assigned studies in accordance with good clinical practice, federal regulations, and institutional policies.
Learning Objectives:
1. To learn the basics of conducting human subject research by completing the training and shadowing our research team.
2. To learn how to conduct research pertaining to infectious diseases with particular emphasis on device-related infections, biofilm and antimicrobial locks.
3. To learn and be involved in research pertaining to novel antimicrobial therapy, antimicrobial stewardship, biomarkers of infections ( Procalcitonin) and COVID19 in cancer patients with infections
Eligibility Requirements:
M.D. or Ph.D. degree.
Mentor Matching:
This position reports to Issam Raad, M.D. See Dr. Raad's research profile.
Institute for Applied Cancer Science
No positions are currently available in this department. Check back later for new opportunities.
Integrative Medicine
No positions are currently available in this department. Check back later for new opportunities.
Interventional Radiology
Req #: 710154-202111191522
Job Title: Postdoctoral Fellow
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A postdoctoral position is immediately available in the Department of Interventional Radiology at The University of Texas MD Anderson Cancer Center at Houston. The main goal of our research is to apply the “see and treat” strategy in the development of targeted imaging and therapeutic agents that will eventually be translated to the clinic to improve the management of cancer through early tumor detection and personalized therapy. Specifically, we focus on the development of next generation imaging techniques and novel agents that have the ability to noninvasively monitor and treat cellular processes at the molecular level that leads to new ways of diagnosing and characterizing disease, developing effective therapeutics, and monitoring response to these treatments.
Learning Objectives:
The main goal of our research is to develop biodegradable medical devices made up of polymeric scaffold that contains therapeutic agents and nanoparticle imaging probes to enhance various therapeutic interventions while at the same time, noninvasively monitor the integrity of the absorbable medical device. The postdoctoral fellow will work on the development and optimization of various medical devices through systematic study of various polymeric scaffolds, and will synthesize various high-Z metal nanoparticles.
Eligibility Requirements:
Highly motivated candidates with a recent Ph.D. in Polymer Chemistry, Chemistry, Biomedical Science, Materials Science, or one of the basic sciences are encouraged to apply. Ideal candidates should have strong laboratory skills in the synthesis and characterization of nanoparticles, liposomes, polymer chemistry, and/or imaging. The successful candidate will have a track record as a successful PhD candidate and have at least two first-authored publications in internationally peer-reviewed scientific journals in one or more of the following areas: polymer science, synthetic chemistry, nanotechnology, drug delivery, and imaging. Prior experience in nanoparticle, liposome or polymer synthesis and characterization, and experience in performing cell culture and animal imaging is highly desirable. The qualified candidates are expected to work independently and as part of a team, self-motivated, have critical thinking abilities and good written and oral communication skills.
Mentor Matching:
This position reports to Marites Melancon, Ph.D. View Dr. Melancon's research profile.
lnvestigational Cancer Therapeutics
No positions in the Department of Investigational Cancer Therapeutics are currently available. Check back later for new opportunities.
Leadership Institute
Req #: 202109111303
Job Title: Postdoctoral Fellow
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The MD Anderson Leadership Institute is seeking a driven individual with an interest in leadership development. In this highly developmental position, you will be working with leadership experts to conduct research on a myriad of programs and topics (e.g., selection, change, coaching, mentoring, teams etc.). You will help evaluate leadership development programs, including creating surveys, analyzing data and visualizing results, and writing manuscripts for publication in academic and practitioner outlets. We are seeking an individual who has a passion for working in healthcare and for leadership research in pursuit of the ultimate goal of safe and efficient patient care.
The ideal candidate will enjoy working on multiple projects simultaneously, have an interest in both research and applied work, and thrive in an autonomous work environment. Candidates with a research interest in leadership development and the evaluation of training will be a good fit. Candidates should also have interest in translating this research to evidence-based best practices and tools for organizations.
This full-time position requires a commitment of 40 hours per week and will work remotely as part of the University of Texas MD Anderson Cancer Center. As a Postdoctoral Fellow, you will gain valuable exposure to a world-renowned healthcare organization and leading experts in leadership development and will develop skills needed to be successful in both the academic and applied fields.
Eligibility Requirements:
Ph.D. degree in I/O Psychology, Human Factors Psychology, or related field • Strong passion for leadership development • Experience in evidence-based program evaluation • Proficiency in all stages of the research process • Previous work on research projects • Ideal candidate will have strong methodological and analytical skills • Proficiency in Excel, SPSS, R, Qualtrics, Power BI • Excellent written and verbal communication, listening, and interpersonal skills • Ability to thrive with minimal direction and supervision
Program Dates:
The position will be for one year with the possibility of extension to two years based on performance and availability.
Mentor Matching:
The Admin Postdoc Fellow will be mentored by Kate Cavanaugh, Ph.D., in the Leadership Institute.
Stipend:
$60,000/year
Leukemia
Req #: 600411-202108051645
Job Title: Postdoctoral Fellow
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A postdoctoral position in the field of Hematopoiesis/Leukemogenesis is available in the laboratory of Dr. Simona Colla in the Department of Leukemia at the University of Texas MD Anderson Cancer Center. Our focus is on defining the role of telomere dysfunction in the pathogenesis of myelodysplastic syndromes and aging-related diseases. Our experimental systems include both genetic mouse models and primary leukemia stem and progenitor cells from MDS patients.
Responsibilities include the following: conducting and managing day-to-day experiments related to the development and progression of MDS; providing the principal investigator with daily updates regarding laboratory and analytical progress; reporting challenges in a timely manner; researching and staying up to date on cutting edge research technology and peer reviewed literature related to the subject matter; communicating with collaborators and colleagues at MD Anderson and elsewhere; supervising and mentoring graduate students and laboratory technicians; writing and submitting grants and publications; presenting data at internal and external meetings, seminars, and conferences; assisting the lab manager with daily laboratory operations; assuring laboratory compliance with institutional, local, state, and national rules and regulations; and other duties as assigned.
Individuals with a PhD degree in the related research field, who are highly motivated and self-directed, with good communication and problem-solving skills, are encouraged to apply.
Learning Objectives:
Under the supervision of the principle investigator, the individual will conduct research aimed at therapeutically targeting leukemia cells using cell culture, signal processing, molecular biology, biochemistry and high-throughput drug discovery-related techniques. The individual will collaborate with other established principal investigators as well.
Eligibility Requirements:
Individuals with a Ph.D. degree in the related research field, highly motivated and self-directed with good communication and problem-solving skills, are encouraged to apply.
- A strong background in hematology/immunology
- Extensive molecular biology, flow cytometry, and immunofluorescence experience is required
- Experience with hematopoietic stem cells and animal models are essential.
- PhD publication with IF in journal with impact factor greater than 10.
- Program Dates: Monday - Friday, 8 a.m. to 5 p.m.; Weekends when needed.
Mentor Matching:
This position reports to Simona Colla, Ph.D. View Dr. Colla's research profile.
Stipend:
Stipend support will follow the NIH NRSA level for the appropriate PGY.
Additional Application Information:
Please submit curriculum vitae to Pamela Lockyer, lab manager of Dr. Simona Colla at pplockyer@mdanderson.org.
Req #: 600411-202108181112
Job Title: Postdoctoral Fellow
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Dr. Michael Andreeff and Dr. Bing Carter, Section of Molecular Hematology & Therapy, Department of Leukemia at the University of Texas MD Anderson Cancer Center invite applications for a postdoctoral position. We are looking for a highly motivated and innovative individual with technical expertise in cell, molecular, or cancer biology to conduct a project for mechanism-based combinatorial targeting of drug-resistant leukemia stem cells.
Learning Objectives:
Applicant will conduct research into cell death and cell survival pathways, and mechanisms of drug resistance in myeloid leukemia stem cells through a combinatorial study of gene mutations, gene expression, protein expression, and responses to drug treatments in leukemia cells. The ultimate goal is to understand the functions of apoptotic regulators, cell signaling pathways, leukemia microenvironmental regulators, and their roles in drug resistance, and develop mechanism-based approach to overcome drug resistance. Researcher will collaborate with established and committed investigators in an interdisciplinary research project that involves cell culture, flow cytometry, mass cytometry, western blot analysis, immunohistochemistry, RT-PCR, DNA/RNA sequencing, and NSGS/NSG mouse models. Researcher will present scientific results in project meetings, national and international conferences, and in high impact scientific publications.
Eligibility Requirements:
The ideal candidate is a recently graduated cell, molecular or cancer biologist PhD with practical experience and excellent knowledge-base in cell death pathways and cell signaling, and with experience in at least one of the following areas of discipline: cell culture, drug treatment, and cell death assay, molecular cloning, flow cytometry, and/or mouse work. Data analysis skill is highly desirable. The applicant enjoys providing practical and theoretical training for students and promotes scientific collaboration within the research group, and will have excellent written and spoken (English) communication skills. The candidate should have one or more publication as first author.
Mentor Matching:
This position reports to Michael Andreeff, M.D., Ph.D., and Bing Carter, Ph.D.
Req #: 600411-202108181116
Job Title: Postdoctoral Fellow
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A postdoctoral research fellowship position is available to study breast cancer stem cells. The laboratory is studying the role of ganglioside GD2 and GD3 synthase in the regulation of cancer stem cell function in triple-negative breast cancer. In particular, we are interested in the development of novel small molecule inhibitors for targeting GD3 synthase in breast cancer cells as a part of DoD funded project. Postdoctoral fellows are responsible for the development of GD3 synthase inhibitors using several molecular and computational approaches and testing the compounds in vitro stem cell assays as well in vivo tumor growth studies. Candidates must have a doctoral degree with 0-2 years of postdoctoral experience. Preference will be given to candidates with previous experience with protein modeling, drug discovery/development, computational tools, mouse models, cancer stem cell biology, basic cell culture, and imaging skills. Candidates are expected to be self-motivated and have excellent writing and communication skills.
Learning Objectives:
The potential candidate is expected to quickly learn various tissue culture techniques, stem cell functional assays, metabolic assays that we routinely use in our laboratory. Also, we have several animal models including patient-derived xenografts that need to be maintained and used for translational research. A thorough understanding of cancer biology, drug development, molecular modeling is appreciated.
Eligibility Requirements:
Ph.D. degree in a life science (cellular or molecular biology). Research experience and an excellent knowledge-base in biochemical, metabolic, and signaling process as they relate to cancer. Experience in breast cancer, molecular cloning, the quantitative measurement of RNA expression, flow cytometry, protein modeling, big data analysis, and/or the use of animal models would be a plus. The applicant should enjoy providing a training role for students and other coworkers, and should be open to scientific collaboration within the institution as well as outside the institution. The candidate should possess excellent written and spoken (English) communication skills and should be able to present scientific data at international meetings.
Program Dates:
December 2021 through November 2022 - Consideration of applications will begin immediately and continue until the position is filled.
Mentor Matching:
This position reports to Lokesh Venkata Battula, Ph.D., Michael Andreeff, M.D., Ph.D., Naoto T. Ueno, M.D., Ph.D.
Additional Application Information:
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments.
A Curriculum Vitae and the contact information of three (3) Referees to Dr. Lokesh Battula with the subject line entitled
“Postdoctoral Fellow - Application – Applicant’s Name” to vbattula@mdanderson.org
Lymphoma-Myeloma
Req #: 600664-202107181110
Job Title: Postdoctoral Fellow
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Researchers interested in postdoctoral fellowships are invited to apply for positions as part of the group led by Dr. Robert Orlowski, Florence Maude Thomas Cancer Research Professor and Director of the Myeloma Section in the Department of Lymphoma/Myeloma at The University of Texas MD Anderson Cancer Center. Our focus is on developing an expanded understanding of the molecular pathobiology of multiple myeloma and related disorders, validating novel targets and therapeutics that can be translated to the clinic, and understanding mechanisms of resistance that could serve as biomarkers and/or targets for chemosensitization. Current projects of interest focus on the activity of a novel, home-grown set of patented monoclonal antibodies that are showing immunomodulatory and direct cytotoxic activity against a variety of tumor models as naked antibodies, antibody-drug conjugates, and in chimeric antigen receptor guided T-cells.
Learning Objectives:
The University of Texas MD Anderson Cancer Center is the nation's #1 ranked cancer center, located within the Texas Medical Center – home to 21 hospitals and 8 academic and research institutes. The postdoctoral fellow will work closely with an interactive team of wet lab scientists and computational biologists in the Green Laboratory, and will have great opportunities to collaborate with diverse groups of physicians, scientists and computational biologists at MDACC and the Texas Medical Center. Houston is a large and vibrant city with an affordable cost of living, two major airports, professional sports teams, and cultural activities.
Eligibility Requirements:
Successful applicants would be part of an established, well funded, committed, and productive interdisciplinary research team of investigators. Ideal candidates would be molecular, cell, and immune biologists with PhD degrees in a closely related field. They should have experience in single cell RNA and TCR sequencing, immunophenotyping and immune assays, and in vivo tumor modeling. He/she should have excellent written and spoken (English) communication skills and promote scientific collaboration within the research group.For those interested, please send a CV, contact information for three references (preferably three letters of recommendation), and a 2 page research statement describing past achievements, skills and research interests to Trish Waitschies at PMWaitschies@mdanderson.org.
Dates or Training Schedule:
Consideration of applications will begin immediately and continue until the position is filled.
Mentor Matching:
This position reports to Robert Orlowski, M.D, Ph.D. See Dr. Orlowski's research profile.
Req #: 600664-202107181120
Job Title: Postdoctoral Fellow
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The laboratory of Dr. Michael Green at the University of Texas MD Anderson Cancer Center is seeking a highly qualified and motivated candidate for an open postdoctoral fellow position. The project is focused on exploring the role of the DTX1 E3 ubiquitin ligase and NOTCH1 in the etiology of diffuse large B-cell lymphoma. The project will employ advanced CRISPR gene editing and next generation sequencing technology, novel transgenic animal models, patient-derived xenograft models, and other primary patient material to understand the role of DTX1 mutations in lymphoma genesis and progression.
Learning Objectives:
The Green lab is part of the Department of Lymphoma & Myeloma and the Department of Genomic Medicine, which offer a highly translational research environment. The lab is well funded through the NIH/NCI, research consortia and other funding mechanisms, and is highly productive. Dr. Green places strong emphasis on trainee mentorship and career development. The University of Texas MD Anderson Cancer Center is the nation's #1 ranked cancer center, located within the Texas Medical Center – home to 21 hospitals and 8 academic and research institutes. Houston is a large and vibrant city with an affordable cost of living, two major airports, professional sports teams, and cultural activities.
Eligibility Requirements:
Applicants should have graduated with their PhD no earlier than 2020 and must have experience with molecular biology. Experience with animal models and/or next generation sequencing and/or bioinformatics is desirable. Interested applicants are invited to submit a C.V. and cover letter.
The University of Texas MD Anderson Cancer Center is the nation’s #1 ranked cancer center, located within the Texas Medical Center – home to 21 hospitals and 8 academic and research institutes. The postdoctoral fellow will work closely with a team of wet lab researchers in the Green Laboratory, and will have great opportunities to collaborate with diverse groups of physicians, scientists and computational biologists at MDACC and the Texas Medical Center. Houston is a large and vibrant city with an affordable cost of living, two major airports, professional sports teams, and cultural activities.
Dates or Training Schedule:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Michael Green, Ph.D. See Dr. Green's research profile.
Req #: 600664-202107181130
Job Title: Postdoctoral Fellow
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The laboratory of Dr. Michael Green at the University of Texas MD Anderson Cancer Center is seeking a highly qualified and motivated candidate for an open postdoctoral fellow position. The project is on the development of Nanopore-based long-read sequencing to understand the genetic and epigenetic etiology and B-cell lymphoma. The project will leverage and extensive tumor bank and cutting edge third generation sequencing technology to understand the effect of structural alterations on epigenetic regulation of gene expression in lymphoma B-cells.
Learning Objectives:
The Green lab is part of the Department of Lymphoma & Myeloma and the Department of Genomic Medicine, which offer a highly translational research environment. The lab is well funded through the NIH/NCI, research consortia and other funding mechanisms, and is highly productive. Dr. Green places strong emphasis on trainee mentorship and career development. The University of Texas MD Anderson Cancer Center is the nation's #1 ranked cancer center, located within the Texas Medical Center – home to 21 hospitals and 8 academic and research institutes. Houston is a large and vibrant city with an affordable cost of living, two major airports, professional sports teams, and cultural activities.
Eligibility Requirements:
Applicants should have graduated with their PhD no earlier than 2020 and must have experience with molecular biology. Experience with animal models and/or next generation sequencing and/or bioinformatics is desirable. Interested applicants are invited to submit a C.V. and cover letter.
Dates or Training Schedule:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Michael Green, Ph.D. See Dr. Green's research profile.
Req #: 600664-202108241543
Job Title: Postdoctoral Fellow
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Dr. Sattva Neelapu and Dr. Neeraj Saini , M.D. at the University of Texas MD Anderson Cancer Center is seeking a highly qualified and motivated candidate for an open postdoctoral fellow position.
Dr. Saini lab is part of the Department of Lymphoma & Myeloma, which offers a highly translational research environment. The lab is well funded through the NIH/NCI, research consortia, and other funding mechanisms.
Postdoctoral position in microbiome and cellular therapies.
Learning Objectives:
A postdoctoral position is available in the field of microbiome and studying its impact on cellular therapies. Our research is focused on discovering novel microbiome related targetable biomarkers that impacts outcomes in CAR-T / TCR-T for both hematological malignancies and solid tumors. Applicants should be graduates with a Ph.D. in immunology/immunotherapy with experience in microbiome in-vivo manipulations, T-cell culture, animal experiments with syngeneic or xenograft tumor models, immune suppression, tolerance, checkpoint blockade, and T cell biology. Experience in working with human immune and tumor cells, animal studies, retrovirus and/or lentiviral generation, molecular cloning, transduction of primary T cells, and flow/mass cytometry is preferred. Candidate will be involved in evaluating novel microbiome biomarkers impact on adoptive T-cell therapy strategies including CAR-T and TCR-T, both in vitro and in vivo models.
Eligibility Requirements:
Candidates should be self-motivated, career oriented, and should be capable of troubleshooting. Excellent verbal and written communication skills, multiple publications, and strong reference letters are required. Interested candidates may send cover letter, CV, and names and contact information of three references to Sattva Neelapu, M.D.
Dates or Training Schedule:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Neeraj Saini, M.D. See Dr. Saini's research profile.
Req #: 600664-202108301127
Job Title: Postdoctoral Fellow
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The Green lab is part of the Department of Lymphoma & Myeloma and the Department of Genomic Medicine, which offer a highly translational research environment. The lab is well funded through the NIH/NCI, research consortia and other funding mechanisms, and is highly productive. Dr. Green places strong emphasis on trainee mentorship and career development. The University of Texas MD Anderson Cancer Center is the nation's #1 ranked cancer center, located within the Texas Medical Center – home to 21 hospitals and 8 academic and research institutes. Houston is a large and vibrant city with an affordable cost of living, two major airports, professional sports teams, and cultural activities.
Learning Objectives:
The laboratory of Dr. Michael Green at the University of Texas MD Anderson Cancer Center is seeking a highly qualified and motivated candidate for an open postdoctoral fellow position focused on defining rationale immunotherapeutic and cellular therapy strategies in diffuse large B-cell lymphoma. The candidate will employ approaches such as single cell multiome sequencing and humanized patient-derived xenograft models, and will join a multidisciplinary group of researchers employing a range of approaches including cutting edge genomics and epigenomics, human tumors, genetically engineered mouse models, and CRISPR gene editing. The position and project are fully funded thanks to support from the Schweitzer Family Fund.
Eligibility Requirements:
Applicants should have graduated with their PhD no earlier than 2020 and must have experience with molecular biology, immunology, or animal models. Interested applicants are invited to submit a C.V. and cover letter to Dr. Michael Green at mgreen5@mdanderson.org.
Dates or Training Schedule:
The appointment is immediately available. Appointee is expected to work 40 hours per week.
Mentor Matching:
This position reports to Michael Green, Ph.D. See Dr. Green's research profile.
Req #: 600664-202109202022
Job Title: Postdoctoral Fellow
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Dr. Sattva Neelapu and Dr. Neeraj Saini , M.D. at the University of Texas MD Anderson Cancer Center is seeking a highly qualified and motivated candidate for an open postdoctoral fellow position. Dr. Saini lab is part of the Department of Lymphoma & Myeloma, which offers a highly translational research environment. The lab is well funded through the NIH/NCI, research consortia, and other funding mechanisms.
Postdoctoral posit on in microbiome and cellular therapies.
Learning Objectives:
A postdoctoral position is available in the field of microbiome and studying its impact on cellular therapies. Our research is focused on discovering novel microbiome related targetable biomarkers that impacts outcomes in CAR-T / TCR-T for both hematological malignancies and solid tumors. Applicants should be graduates with a Ph.D. in immunology/immunotherapy with experience in microbiome in-vivo manipulations, T-cell culture, animal experiments with syngeneic or xenograft tumor models, immune suppression, tolerance, checkpoint blockade, and T cell biology. Experience in working with human immune and tumor cells, animal studies, retrovirus and/or lentiviral generation, molecular cloning, transduction of primary T cells, and flow/mass cytometry is preferred. Candidate will be involved in evaluating novel microbiome biomarkers impact on adoptive T-cell therapy strategies including CAR-T and TCR-T, both in vitro and in vivo models.
Eligibility Requirements:
Candidates should be self-motivated, career oriented, and should be capable of troubleshooting. Excellent verbal and written communication skills, multiple publications, and strong reference letters are required. Interested candidates may send cover letter, CV, and names and contact information of three references to Sattva Neelapu, M.D.
Dates or Training Schedule:
The appointment is immediately available. Appointee is expected to work forty hours per week.
Mentor Matching:
This position reports to Neeraj Saini, M.D. See Dr. Saini's research profile.
Melanoma Medical Oncology
No positions are currently available in this department. Check back later for new opportunities.
Molecular & Cellular Oncology
Req #: 127800-202107181110
Job Title: Postdoctoral Fellow
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The research project focuses on understanding the roles of epigenetic modifiers in regulating cancer-epigenetic events and stem cell characteristics. In particular, the project seeks to identify novel functions of epigenetic modifiers (with an emphasis of histone methylation modifiers) and their new partner proteins in tumor suppression pathways, tumorigenesis and stem cell properties.
Learning Objectives:
To learn epigenetic regulation of cancer and stem cells and become an independent scientist in the field.
Eligibility Requirements:
A Ph.D. in cancer biology or molecular biology is required. Experience and publications in the field of epigenetics are preferred.
Mentor Matching:
The position reports to Min Gyu Lee, Ph.D. View Dr. Lee's research profile.
Additional Application Information:
Please send CV and information for at least three references to:
Min Gyu Lee, Ph.D.
Associate professor
Dept. of Molecular & Cellular Oncology
The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Houston, TX 77030
Email: mglee@mdanderson.org
Req #: 127800-202107260703
Job Title: Postdoctoral Fellow
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Postdoctoral positions are immediately available. These positions offer an exceptional opportunity to study epigenetic regulation of cancer and stem cells. The research in the laboratory focuses on understanding the roles of epigenetic modifiers in regulating cancer-epigenetic events and stem cell characteristics. In particular, we seek to identify novel functions of epigenetic modifiers (with an emphasis of histone methylation modifiers) and their new partner proteins in tumor suppression pathways, tumorigenesis and stem cell properties. In fact, we have discovered new histone methylation modifiers, characterized histone methylation modifiers as a stemness or differentiation factor, and identified histone methylation modifiers/readers as oncogenic factors or tumor suppressors. Some of our selected publications include Cancer Cell (2020), Nature Commun (2019), Molecular Cell (2018), Molecular Cell (2016), J Clin Invest (2013), Genes & Dev (2012), Cell (2007), and Science (2007).
We closely collaborate with many outstanding groups in The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, and other prestigious institutes in the US.
A Ph.D. and publications in the field of cancer biology or molecular biology or epigenetics are required. A recently graduated Ph.D. (no more than 3 years) is preferred.
Eligibility Requirements:
Must have a Ph.D. and publications in the field of cancer biology or molecular biology or epigenetics.
Mentor Matching:
The position reports to Min Gyu Lee, Ph.D. View Dr. Lee's research profile.
Req #: 127800-202107260654
Job Title: Postdoctoral Fellow
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A postdoctoral position is available immediately in Dr. Beretta's Laboratory, Department of Molecular and Cellular Oncology, MD Anderson Cancer Center. The incidence of liver cancer is on the rise in the United States. The overall survival rate from this cancer is poor as most patients are diagnosed late and there are only limited therapeutic options available. Early detection and prevention are promising paths to reduce liver cancer mortality. A successful candidate will be part of a major translational research effort integrating molecular profiling from genomics, metagenomics to metabolomics and spatial transcriptomic, to identify novel targets for therapy, prevention and/or diagnosis, and validate them in preclinical mouse models and patient cohorts.
We are looking for career-oriented and highly-motivated individuals with a PhD or MD/PhD in biological sciences, to join our highly interactive research team. Candidates should have a strong research background in designing and performing molecular and cellular experiments, along with a strong ability to analyze large datasets. Preferred candidates will have experience with mouse models and have demonstrated competence with publications in internationally recognized journals.
Candidates should be enthusiastic and self-motivated, with strong problem solving and organizational skills. Candidates should also have excellent communication skills to work in a highly collaborative team. Prior experience in the field of Hepatology is preferred. Recent graduates are encouraged to apply.
We have a track record of training the best and the brightest postdoctoral fellows who have become exceptional independent group leaders in United States and other countries. The research environment at MD Anderson is outstanding and nurturing, especially for applicants interested in translational research.
Eligibility Requirements:
Must have a Ph.D. or M.D./Ph.D. in biological science.
Mentor Matching:
The position reports to Laura Beretta, Ph.D. View Dr. Beretta's research profile.
Req #: 127800-202109141655
Job Title: Postdoctoral Fellow
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The central mission of the Yu Laboratory is to address fundamental questions in cancer biology, cancer metastasis, tumor microenvironment, and tumor immunology using multidisciplinary approaches, including, but not limited to, immune profiling by CyTOF and single-cell sequencing, molecular imaging, human breast cancer specimens and bioinformatics. Our research encompasses studies of cancer cell signal transduction, tumor immune microenvironment, tumor antigen presentation by dendritic cells, tumor antigen reactive T-cells in tumor initiation, progression, and response to immunotherapies. We are also identifying new targets for breast cancer immunoprevention and immunotherapies and developing novel strategies to benefit cancer patients in carefully designed clinical trials.
Learning Objectives:
This postdoc fellowship will focus on studying novel strategies to boost immune surveillance and enhance the efficacy of immunoprevention and immunotherapies against breast cancer using genetic engineered mouse models and humanized mouse models.
Eligibility Requirements:
Candidates should have a PhD or MD/PhD in related research areas with less than three years in postdoctoral fellow rank. The candidate should have a minimum of two first-authored publications in reputable international journals. Motivated and talented candidates with experiences in tumor immunology and mouse models are strongly desirable.
Mentor Matching:
The position reports to Dihua Yu, M.D., Ph.D. View Dr. Yu's research profile.
Additional Application Information:
Please send your CV and the names/phone numbers/email addresses of three referees to administrative contact: Ms. Irene Shih at ireneshih@mdanderson.org.
Req #: 127800-202109201803
Job Title: Postdoctoral Fellow
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Drs. Liuqing Yang and Chunru Lin, from the Department of Molecular & Cellular Oncology at MD Anderson Cancer Center, are interested in the functional role of long non-coding RNAs (lncRNAs) in cancer and genetic disease. We have demonstrated the molecular mechanisms of long non-coding RNAs in a variety of signaling pathways, including those that regulate breast cancer metastasis and metabolic reprogramming (Cell 2014, NCB 2016, NCB 2017, Cell Research 2019, Nature Immunol. 2019, NCB 2020, Science 2021). The laboratory is also investigating the functional importance of long noncoding RNAs in metabolic disorders. We have been developed CRISPR/Cas9-mediated lncRNA editing/knockout/knockin mouse models, and transgenic mouse models. Our newest projects will study lncRNAs' functional roles in the development of breast/pancreatic cancer, and metabolic disorders using the above mentioned mouse models. Postdoc candidates should possess mastery of basic techniques in biochemistry, cell biology, immunology, and mouse genetics.
Learning Objectives:
The postdoc fellow will learn the cutting-edge methods to seek novel therapy targets for human cancers and metabolic disorders; to learn the design and execution of experimental work, and data analysis; to learn to present results at internal and international meetings; to learn to publish data in top scientific journals.
Eligibility Requirements:
PhD in Molecular Biology, Biochemistry or related field.
Outstanding publication record.
Strong previous experience in biochemistry.
Prior experience in RNA biology is preferred.
Prior experience in genetic mouse models is preferred.
Excellent communication with a focus on teamwork is required.
Program Dates:
Available immediately
Mentor Matching:
The position reports to Chunru Lin, M.D., Ph.D. View Dr. Lin's research profile
Req #: 127800-202201111501
Job Title: Postdoctoral Fellow
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The lab has demonstrated the molecular mechanisms of long non-coding RNAs in immune suppressive tumor microenvironment, immunometabolism, cancer metastasis and metabolic reprogramming (Cell 2014, NCB 2016, NCB 2017, Cell Research 2019, Nature Immunol. 2019). The laboratory is also investigating the functional importance of long noncoding RNAs in metabolic disorders (NCB 2020, Science 2021).
Learning Objectives:
The lab has developed CRISPR/Cas9-mediated lncRNA editing/knockout/knockin mouse models, and transgenic mouse models. The newest projects will study lncRNAs’ functional roles in immunotherapy and metabolic disorders and develop innovative therapeutic strategies using the above-mentioned mouse models. The trainee will use cutting-edge methods to seek novel therapy targets for human cancers and metabolic disorders; design and execution of experimental work, data analysis and their written records; attend and present at internal and international meetings; publish data in top scientific journals.
Eligibility Requirements:
PhD in Molecular Biology, Biochemistry or related field
Outstanding publication record
Strong previous experience in biochemistry
Prior experience in RNA biology is preferred.
Prior experience in genetic mouse models is preferred.
Excellent communication with a focus on teamwork is required.
Program Dates:
6/1/2022
Mentor Matching:
The position reports to Liuqing Yang, Ph.D. View Dr. Yang's research profile
Neuro-Oncology
Req #: 408500-202111170828
Job Title: Postdoctoral Fellow
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Program/Position Description:
The research projects focus on the roles of growth factor receptors and other protein kinases in regulating cellular signal transduction, which contributes to oncogenesis and tumor invasion and metastasis. The main project focuses to conduct research into DNA damage Repair pathways, DNA Damage Response and Oncogenic Signaling. Our goal is to combine a basic understanding of DNA repair pathways in tumors with the development of biomarkers that predict tumor response to DNA damaging chemotherapies as well as DNA repair pathway inhibitors.
The goal is to understand the mechanisms of drug resistance in brain tumor stem cells through a combinatorial study of gene mutations, gene expression, protein expression, and responses to drug treatments.
Learning Objectives:
The candidate will be learning experimental design, data analysis and manuscript preparation, lab meetings, journal clubs, and research seminars. The post Doc will learn state of art molecular biology, cellular biology research pertaining to brain tumors.
Eligibility Requirements:
Need Ph.D. degree with 0 years of experience.
Major field: Biochemistry.
Dates or Training Schedule:
N/A
Mentor Matching:
This position reports to W K Alfred Yung.
Req #: 408500-202108171238
Job Title: Postdoctoral Fellow
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Dr. Fueyo and Dr. Gomez-Manzano viroimmunotherapy laboratory seeks highly motivated post-doctoral research fellows to investigate the development of new therapeutic approaches for the primary and metastatic brain tumors. Prior experience in molecular and cell biology, as well as immunology is highly desirable. The candidate must be self-driven, ethical, and a team player.
We have generated oncolytic adenoviruses with selective replication in cancer cells, tested preclinically and move these agents to first-in-human clinical application, and then to multicentric clinical trials. Our current studies are focused on finding new avenues for improving the results obtained in the clinical arena. The research has both basic and translational components and will encompass the use of molecular and cellular biology, as well as immunology and models of solid cancers.
Interested applicants should send a CV, cover letter, statement of research interest and contact information for three references via email to Juan Fueyo, MD (jfueyo@mdanderson.org) or/and Candelaria Gomez-Manzano, MD (cmanzano@mdanderson.org), Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX.
Learning Objectives:
Acquiring expertise in new methodology, manuscript and grant writing, oral presentation. Team working structure. Participate in educational activities.
Eligibility Requirements:
Applicant must hold a Ph.D./M.D. degree less than 3 years ago, and have experience in laboratory research since the graduation.
Mentor Matching:
The position reports to Juan Fueyo, M.D. See Dr. Fueyo's research profile.
Neurosurgery
Req #: 600378-202111091813
Job Title: Postdoctoral Fellow
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The post-doctoral position will involve retrospective clinical research in the areas of spinal tumor. There will be a particular emphasis in collecting clinical, radiological, demographic and outcome data. The candidate will be performing statistical analysis and preparing scientific publications.
Learning Objectives:
The postdoc will receive training and mentoring in the composition of scientific manuscripts, will be involved with analyzing radio graphical data and outcome measures, analyzing the results of multiple different treatment strategies for spinal tumors. The impact of radiation therapy, surgical techniques, image guidance, systemic treatment options and targeted therapies will also be analyzed and will improve the fellow knowledge on updated multi-modality treatments for spinal oncologic cases.
Eligibility Requirements:
The applicant should have a MD degree, basic knowledge of statistical method and be able to compose peer-reviewed publications to be published in internationally recognized journals. A strong background in spinal surgery is required.
Program Dates:
January 2022 to January 2023
Mentor Matching:
The position reports to Claudio Tatsui, M.D. See Dr. Tatsui's research profile.
Req #: 600378-202111091817
Job Title: Postdoctoral Fellow
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The postdoctoral position will involve basic and translational research in the areas of brain tumor cell biology and mouse models of primary and metastatic brain cancer. There will be a particular emphasis on the brain microenvironment, including studies of how primary and metastatic tumor cells co-opt the neurovascular unit/blood-brain barrier for selective growth and survival.
Learning Objectives:
The postdoc will receive training and mentoring in the use of mouse models and in vitro culture systems to study cell adhesion and signaling pathways involved in tumor cell-stromal cell interactions. Biochemica, molecular geneticl and cell biological techniques will also be emphasized.
Eligibility Requirements:
The applicant should have a PhD and/or MD as well as peer-reviewed publications or manuscripts under review in internationally recognized journals. A strong background in biochemistry, molecular biology, and cell biology is also required.
Program Dates:
June 2022 - June 2026
Mentor Matching:
The position reports to Joseph McCarty, Ph.D. Dr. McCarty has expertise in brain tumor biology and will serve as a mentor for post-doctoral studies in brain cancer research. See Dr. McCarty's research profile.
Req #: 600378-202111300829
Job Title: Postdoctoral Fellow
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We are looking for highly self-motivated candidates with a PhD or MD/PhD degree with intravital multi-photon imaging expertise for tumor immunology and cancer nanomedicine studies.
Project topics include but are not limited to metastasis of cancer cells, cancer cell biology and migration, nanomedicine, biomechanics, and development of novel, targeted therapeutic interventions. A successful candidate must have a strong background in multi-photon microscopy, and interest in applying state of the art intravital microscopy to pre-clinical brain, breast, lung and melanoma cancer models.
Our laboratory has a broad interest in the design of novel immune nanomedicines and immunotherapy strategies to optimally diagnose and treat solid tumors. We also use advanced bioimaging platforms that enable real-time, long-term tracking and characterization of specific immune interactions involved in human diseases including stroke, cancer and neurodegenerative diseases. We have a multi-disciplinary team in tumor immunology, bioengineering, nanotechnology, advanced in vivo imaging. Our lab has published extensively in these areas. Please submit a curriculum vitae and a brief cover letter, including contact information for 3-5 references to Dr. Kim by email: bykim@mdanderson.org
Learning Objectives:
Learning to use multiphoton microscope to study tumor cell - immune cell interactions in vivo and deciphering the mechanisms of cancer immunotherapy responses
Eligibility Requirements:
PhD is engineering, tumor biology, imaging/fluorescence microscopy or related disciplines. Experience with multiphoton imaging platform would be a major advantage.
Program Dates:
1/3/2022-1/2/2023
Mentor Matching:
The position reports to Yon Son Betty Kim, M.D., Ph.D. Dr. McCarty has expertise in brain tumor biology and will serve as a mentor for post-doctoral studies in brain cancer research. See Dr. Kim's research profile.
Req #: 600378-202112091201
Job Title: Postdoctoral Fellow
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The ideal candidate will investigate cancer-intrinsic pathways to regulate immune evasion. Particularly, the focus will be identifying epigenetic pathways involved in tumor immune interactions. The primary purpose of this position is to perform basic and translational research in molecular biology and biochemistry techniques related to the development of new therapeutic vulnerabilities of cancer cells via epigenetic pathway modulation. Experience in laboratory management and procurement is important.
Learning Objectives:
- Daily responsibilities will include performing molecular and cell biological techniques including mammalian cell and tissue culture, surgical specimen collection and preparation, flow cytometry, transfection of human primary T cells and cell lines, culture of genetically modified primary human T cells, cytotoxicity assays, and various similar assays.
- Other responsibilities include evaluating immunotherapies in murine models of glioblastoma and lung adenocarcinoma, including establishing intracranial xenografts, delivering treatment via i.v. tail vein injection, and monitoring mice via bioluminescent imaging, performing necropsies, cell isolation from tissues, and histological preparation of tissues.
- Weighs and observes mice for tumor growth. Sacrifices and necropsies mice for pathological examinations. Stores and analyzes animal tissue and keeps records of the location of respective samples. Must be willing to learn new techniques as applicable.
- Plans, organizes, coordinates and participates in scientific research projects under the direction of a professional staff member. Collaborates with other research scientists to design experiments involving genetically modified T cells, flow cytometry, immune assays, and treating murine models of glioblastoma and lung adenocarcinoma.
Eligibility Requirements:
Ph.D. in Immunology, Biochemistry, Molecular Biology, Genetics or a related field. A first author publication in press, accepted or on BioRxiv. Excellent communication skills is required. The ideal candidate will be independent, organized, and proactive with strong communication skills. Must demonstrate outstanding personal initiative and the ability to work effectively as part of a team.
Program Dates:
April 2022 - April 2026
Mentor Matching:
The position reports Kadir C. Akdemir, Ph.D. See Dr. Akdemir's research profile.
Nursing Fellowship
Req #: 600778-202109301423
Job Title: Postdoctoral Fellow
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The Postdoctoral Fellowship Program provides advanced training in outcomes research for nurses who completed a doctoral degree (PhD) from an accredited university in nursing or a field relevant to oncology health care outcomes research, behavioral and clinical interventions, and data science and would like the opportunity to further develop a research career in oncology. The program will provides mentorship and guidance from a faculty mentor. The Fellow will develop an original research program under the guidance of a primary faculty mentor, participate in research seminars and training experiences, and engage in individual and group mentoring sessions with distinguished faculty mentors from MD Anderson Cancer Center. The fellowship will provide the mentee guidance on development of a program of research, grant development, project management, advanced methods, manuscript development, networking opportunities with distinguished faculty mentors.
GOALS:
- Extend research knowledge
- Conduct research with interdisciplinary team
- Develop grant writing, publication and communication skills
- Develop interdisciplinary and intradisciplinary networks
- Outcomes
- Prepare and submit manuscripts to publication including at least one first author publication.
- Prepare and submit grants for research funding.
- Achieve grant funding
- Establish a research platform and trajectory
Learning Objectives:
Fulfill personal development goals and the fellowship goals through an individualized curriculum
Establish collaborative relationships with faculty mentors and peer researchers
Participate in ongoing postdoctoral research forums
Prepare and submit manuscripts for publication including at least one first author publication
Prepare and submit grants for research funding
Develop a research platform and trajectory
Eligibility Requirements:
Education: Ph.D. in Nursing or related field from an accredited university. If Ph.D. is not in nursing, must have a minimum of a master's level degree in nursing
Licensure: Licensed or eligible for licensure as an RN in the state of Texas
Experience: at least 5 years of experience as a clinical or advanced practice nurse
Preferred: prior experience in nursing research
Mentor Matching:
The position reports to Anecita Fadol, PhD. See Dr. Fadol's research profile.
Pain Medicine
Req #: 600879-202111041830
Job Title: Postdoctoral Fellow
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This position is for a postdoctoral fellow with interest in the theme of neuropathic pain. The goal of the program is to understand the molecular and electrophysiological mechanisms of dorsal root ganglion after neuronpathic pain. Specifically, we are interested in studying the activities changes of dorsal root ganglion neurons and the potential prevention strategies. We will also study the molecular mechanisms during neuropathic pain in rat and mouse.
Learning Objectives:
- To develop a rat and mice model of neuropathic pain.
- To learn behavioral tests for neuropathic pain.
- To learn rat/mouse/ human DRG neuron culture
- To learn patch clamp recording on cultured DRG neurons
- To learn and develop molecular techniques to understand mechanisms related to neuropathinc pain.
Eligibility Requirements:
Ph.D. with background in neuroscience.
Program Dates:
2/1/2022-1/31/2023
Mentor Matching:
The position reports to Patrick M. Dougherty, PhD. See Dr. Dougherty's research profile.
Palliative, Rehabilitation and Integrative Medicine
No positions are currently available in this department. Check back later for new opportunities.
Pathology
Req #: 600663-202109131321
Job Title: Postdoctoral Fellow
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The main goal of this postdoctoral position is to work in a multidisciplinary research hematopathology team, focused on pathology projects designed to improve our understanding of hematological cancers. The postdoctoral fellow will develop scientific projects, analyze and interpret data, manage data and communicate the scientific findings at informal and formal meetings and preparing manuscripts for publication in peer-review journals. Expertise in histopathology is required.
The post-doctoral fellow will review and annotate pathology blocks/slides of hematologic cancers in conjunction with a pathologist. The fellow will also assist in obtaining pathology blocks from outside institutions, maintaining a database regarding these specimens, perform or organize various studies utilizing various methods applied to these specimens including immunohistochemistry, in situ hybridization, polymerase chain reaction-based methods, and digital pathology-based methods of analysis.
Develop and perform scientific research projects on hematologic cancers, with a focus on lymphomas. Currently, splenic lymphomas and small lymphocytic lymphoma/chronic lymphocytic leukemia are active projects, but these projects will likely evolve or change over the time interval the post-doctoral fellow is on board.
Collect, annotate, archive, and process biospecimens from ongoing clinical research studies. There will be a focus on preparing DNA or RNA from specimens as needed for each study.
Learning Objectives:
- Develop skills for collaboration and translation of laboratory-based findings with a focus on biomarkers and assessment of outcomes and response.
- Learn how to perform digital pathology analysis
- Acquire skills in the statistical analysis of pathology data.
- Support more senior pathologists and develop research projects independently.
- Learn aspects of hematological cancer research undertaken in a hospital/research institute.
- Acquire skills for progression in academia including but not limited to delivering presentations.
- The trainee, along with the mentor, will present their data in informal laboratory and more formal academic pathology meetings.
- The trainee will participate in departmental education activities.
Eligibility Requirements:
An individual holding an M.D. or Ph.D. or equivalent who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity. Expertise in Histopathology is required as well as a completion of a residency/fellowship program. The applicant will have to be supported by her/his Institution.
Program Dates:
01/11/2022 to 01/10/2023
Mentor Matching:
The position reports to Jeffrey Medeiros, M.D.
Pediatrics
Req #: 130100-202110181858
Job Title: Postdoctoral Fellow
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Duties and Responsibilities: A leading translational immune therapy research lab in the Division of Pediatrics at The University of Texas MD Anderson Cancer Center seeks a highly motivated postdoctoral fellow with a strong interest in immune therapy and a desire to work with projects relating to the interaction between genetic mutations in pediatric-related tumor cells and immune cells in promoting tumorigenesis, tumor progression and tumor metastasis. In specific, signaling changes due to the genetic mutations in tumor cells on immune regulatory gene expression in both immune and tumor cells will be investigated. Interventions using immune therapy in combination with small molecules on the immune regulatory genes expression and the associated immune response will be also investigated. How, projects will be also developed based on the interest of each individual fellow or trainee. The lab's recent efforts focus on discovery of novel combination treatments for boosting T-cell (autologous, TIL, and CAR T cells) deep penetration/infiltration into solid tumors, referred to as iTIL therapy.
Learning Objectives:
This lab focuses on the discovery of novel immune therapy and the underlying mechanisms. The lab is interested in discovering novel approaches of immune therapy and diagnosis and is exploring the use of a self-developed universal circulating tumor cell (CTC) detection tool for examining the immune response to therapy.
Eligibility Requirements:
Qualified postdoc candidates should have a doctoral degree, with strong experience in cell therapy or uncovering molecular or cellular mechanisms.
Mentor Matching:
The position reports to Shulin Li, Ph.D. See Dr. Li's Research profile.
Plastic Surgery
No positions in the Department of Plastic Surgery are currently available. Check back later for new opportunities.
Pulmonary
Req #: 600469-202107281805
Job Title: Postdoctoral Fellow
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Lung adenocarcinoma (LUAD), is still the leading cause of cancer mortality. Unfortunately, lung cancer patients harboring activating mutations of K-ras, which are heavily associated with tobacco exposure and poor prognosis, are resistant to most forms of systemic or targeted therapies. This fact clearly indicates that there is an urgent unmet need for alternative strategies targeting downstream effectors of K-ras and/or its cooperating pathways for treatment and prevention of K-ras mutant LUAD (KM-LUAD). Accordingly, our research program is focused on airway inflammation, intrinsic (e.g. oncogene driven) and extrinsic (e.g. smoke or infection induced), and its role in airway epithelial tumorigenesis. It is known that mutant epithelial cells begin to edit the microenvironment as soon as they transform but the exact mechanisms involved in this immuno-editing process from escaping the immunosurveillance to tumor progression and contribution of pro-tumor inflammatory signals in this process still not well understood.
Our laboratory has developed and interrogated various human-relevant mouse models that closely emulate the molecular pathobiology of human airway inflammation, COPD, and lung cancer. We have previously shown that a network of immunomodulatory cytokines released during inflammation promotes lung tumorigenesis by providing a pro-tumor lung microenvironment in a genetic mouse model of lung cancer with K-ras mutation. We have further shown that targeting inflammatory pathways and modulating this cytokine network could be used as a preventive and therapeutic strategy for KM-LUAD. We are currently dissecting the cell-specific autocrine and paracrine mechanisms responsible for this phenomenon. We employ genetic and pharmacologic targeting interventions, immunophenotyping, histopathology, single-cell RNA sequencing, and other RNA- and protein-based approaches to study the effect of targeting these pathways on tumor cells and changes in immunomodulatory responses in vivo that could affect the pathogenesis of KM-LUAD.
These studies have the potential to detect and target important immunomodulatory pathways in the lung tumor cells and infiltrating immune cells, which could have major impacts on personalized prevention and treatment of lung cancer. They will also lay the groundwork to develop predictive and prognostic biomarkers to identify responders and non-responders.
Learning Objectives:
1. To prepare and conduct in vivo studies of lung inflammatory microenvironment and lung cancer using mouse models.
2. To prepare and conduct ex vivo/in situ histologic analyses using the following techniques: animal dissection, tissue fixation, paraffin embedding, cryofixation, tissue sectioning (paraffin and frozen), histochemistry, immunohistochemistry, and immunofluorescence staining.
3. To performs microscopic and morphometric image analyses of histological specimens.
4. To perform RNA and protein-based analysis of tumor and immune cells.
5. To perform cell sorting and flow cytometry of lung infiltrating immune cells.
6. To extract and record relevant information from published literature.
7. To learn data analysis, and graph/figure preparation for presentations (poster, and oral), manuscripts, reports, and grant proposals.
8. To learn writing and submitting manuscript as well as grant proposal.
9. To present at the local, national, and international meeting.
10. To co-mentor undergrad, graduate students, and other trainees.
Eligibility Requirements:
EDUCATION: Required: PhD
EXPERIENCE: Required: Basic molecular biology and immunology techniques are required. Work experience with small rodents is a plus.
Mentor Matching:
The position reports to Seyed Javad Moghaddam, M.D. View Dr. Moghaddam's research profile.
Req #: 600469-202108241231
Job Title: Postdoctoral Fellow
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This position will study the role of the complement system on the tumorigenesis and progression of cancer.
1. To design and conducts in vitro experiments on the role of complement proteins in cancer cell proliferation and morphological changes
2. To design and conducts in vitro experiments on the role of complement proteins in proliferation, differentiation, and polarization of T cells
3. To design and conducts in vivo experiments using mouse models of cancers to study the effect of the complement system in growth and metastasis of different cancers, and the therapeutic benefit of complement inhibitors on blocking tumor growth.
4. To conduct animal dissections and prepare tissue specimens from tumors for processing: fixation, paraffin embedding, cryofixation, tissue sectioning (paraffin and frozen), histochemistry, immunohistochemistry, immunofluorescence microscopy, and in situ hybridization.
5. To perform imaging studies from tumor specimens: light microscope, immunofluorescence microscopy, and morphometric image analyses.
6. To conduct DNA, RNA, and protein extraction and purification.
7. To conduct DNA, RNA, and protein analysis by PCR, RT-PCR, Quantitative PCR, acrylamide gel electrophoresis, ELISA, and Western blotting.
8. To be up-to-date with the literature relevant to her project on complement biology and cancer immunology
9. To communicate freely and clearly, but also to be respectful to other lab members.
10. Records the experiments and results meticulously.
11. Analyze data, prepare graphs, figures, and help in writing and submitting the manuscript.
Learning Objectives:
1. Learning to design and conduct experiments in vitro and in mouse models of cancer
2. Learning to troubleshoot and analyze the generated data
3. Learning important topic in complement biology, the immune response to the tumor, immune profiling tumor microenvironment, mouse genetics
Eligibility Requirements:
Ph.D. in biological sciences
Familiarity with murine studies
Familiarity with basic laboratory techniques, such as flow cytometry, ELISA, Western blotting, PCR, RT-PCR, RNA, and DNA extraction
Mentor Matching:
The position reports to Vahid Afshar-Kharghan, M.D. View Dr. Afshar-Kharghan's research profile.
Req #: 600469-202108241234
Job Title: Postdoctoral Fellow
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This position will study the role of the platelets in the progression of cancer and on the mechanisms of platelet extravasation into tumors.
1. To design and conducts in vitro experiments on the role of platelets in cancer cell proliferation and morphological changes
2. To design and conducts in vitro experiments on the role of platelets on immune cells (neutrophils, T cells, B cells, and antigen-presenting cells)
3. To design and conducts in vivo experiments using mouse models of cancers to study the effect of platelets on the growth and metastasis of different cancers, and the therapeutic benefit of platelet inhibitors on blocking tumor growth.
4. To design and conducts in vivo experiments using mouse models of cancers to investigate the mechanism of platelet extravasation into the tumor microenvironment.
5. To design and conducts in vivo experiments using mouse models of cancers to investigate the mechanism of platelets on the immune profile of tumor microenvironment.
6. To conduct animal dissections and prepare tissue specimens from tumors for processing: fixation, paraffin embedding, cryofixation, tissue sectioning (paraffin and frozen), histochemistry, immunohistochemistry, immunofluorescence microscopy, and in situ hybridization.
7. To perform imaging studies from tumor specimens: light microscope, immunofluorescence microscopy, and morphometric image analyses.
8. To conduct DNA, RNA, and protein extraction and purification.
9. To conduct DNA, RNA, and protein analysis by PCR, RT-PCR, Quantitative PCR, acrylamide gel electrophoresis, ELISA, and Western blotting.
10. To be up-to-date with the literature relevant to her project on complement biology and cancer immunology
11. To communicate freely and clearly, but also to be respectful to other lab members.
12. Records the experiments and results meticulously.
13. Analyze data, prepare graphs, figures, and help in writing and submitting the manuscript.
Learning Objectives:
1. Learning to design and conduct experiments in vitro and in mouse models of cancer
2. Learning to troubleshoot and analyze the generated data
3. Learning important topic in platelet biology, imaging studies, immune profiling tumor microenvironment, mouse genetics
Eligibility Requirements:
Ph.D. in biological sciences
Familiarity with murine studies
Familiarity with basic laboratory techniques, such as ELISA, Western-blotting, flowcytomtery, RT-PCR, PCR, RNA, and DNA extraction
Familiarity with imaging studies including immunohistochemistry and immune fluorescence microscopy
Mentor Matching:
The position reports to Vahid Afshar-Kharghan, M.D. View Dr. Afshar-Kharghan's research profile.
Req #: 600469-202110211632
Job Title: Postdoctoral Fellow
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A fully funded postdoctoral fellowship position is immediately available in the Laboratory of Scott Evans at the University of Texas MD Anderson Cancer Center. Pneumonias are a leading cause of death in all populations, and exact a particularly severe toll on immunocompromised individuals, such as cancer patients receiving cytotoxic therapies. In an effort to protect vulnerable patients against lethal pneumonias, the Evans lab investigates means to manipulate the lungs' intrinsic antimicrobial defenses to protect against the pathogens that people inhale or aspirate every day. Rather than rely on the canonical responses of leukocytes that are often deficient or dysfunctional in cancer patients, the focus of our work is on manipulating microbicidal responses directly from lung epithelial cells, a long-lived cell population that is largely tolerant of cytotoxic therapies. Using this approach, the Evans lab has discovered epithelium-focused immunostimulatory therapies that are now in FDA-approved clinical trials in a variety of settings. Our work now focuses on understanding how this manipulation can prevent both acute (lethal pneumonia) and chronic (asthma) complications of respiratory infections. Such understanding can allow development of next-generation therapies that exert even greater efficacy with even fewer off-target effects. Active projects in the laboratory include investigations into novel mechanisms to detect pathogens, into mechanisms of intra- and inter-cellular signaling events that promote synergistic protective responses, into the inducible microbicidal effector mechanisms that reduce pathogen burdens, and into immunomodulatory effects of our epithelial treatments that exert their effects independent of pathogen burden.
The Evans lab has "shovel ready" projects for postdoctoral fellows to lead on day one, but given the unconventional nature of the lab's programs, applicants' novel ideas for new projects are also encouraged. The Evans lab strives to be inclusive and supports a highly collaborative, team-oriented, learner-driven environment.
Learning Objectives:
To prepare and conduct in vivo studies of pneumonia and pneumonia protection in wildtype and genetically-manipulated mice.
To prepare and maintain cultures of immortalized and primary cells to investigate mechanisms of inducible protection.
To prepare and conduct ex vivo/in situ histologic analyses using the following techniques: animal dissection, tissue fixation, paraffin embedding, cryofixation, tissue sectioning (paraffin and frozen), histochemistry, immunohistochemistry, and immunofluorescence staining.
To perform microscopic and morphometric image analyses of histological specimens.
To perform RNA and protein-based analysis of epithelial cells and leukocytes.
To perform cell sorting and flow cytometry to characterize immune responses.
To extract and record relevant information from published literature.
To learn data analysis and figure preparation for presentations.
To learn to write and submit manuscripts and grant proposals.
To present data and literature reviews at local, national, and international meetings.
To mentor undergraduate, graduate students, and other trainees.
To develop organizational and leadership skills in preparation for a career in science.
Eligibility Requirements:
Successful applicants must have MD and/or PhD degrees with experience in immunology, microbiology, epithelial biology or other fields directly relevant to host-pathogen interactions. Postdoctoral fellows should be familiar with basic cell biology and immunology techniques. Strong written and spoken English communication skills are important to the positions, as successful applicants will participate in writing grants and papers, will present findings and novel research in various formats, and will provide supervision to more junior trainees. Experience with small rodents is a plus.
Mentor Matching:
The position reports to Scott Evans, M.D. View Dr. Evans' research profile.
Radiation Oncology
Req #: 600661-202107181120
Job Title: Postdoctoral Fellow
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The program is introducing a formal one-year educational and research program that will effectuate expertise sufficient to lead and accelerate the development of biomedical imaging application in radiation oncology. We aim to develop and effectuate a program that includes a mentored
education, training, and hands-on implementation of research activities related to biomedical imaging, clinical informatics, and clinical trial design and to enhance the recruitment of early career physician scientist from under-represented minorities or with disabilities or other social, cultural, economic, or educational disadvantages to enrich the diversity of our national workforce in biomedical imaging. Successful implementation of this program will directly augment novel research approaches towards the development of new biomedical imaging techniques and devices to fundamentally improve the detection, treatment, and prevention of disease; as well as enhancing existing imaging and clinical research and its implications.
Learning Objectives:
One of our direct objectives is to inculcate trainees with requisite research skills for integration of biomedical imaging and clinical imaging informatics in radiation oncology applications.
Eligibility Requirements:
Domestic resident post-graduate physician trainees (PGY1-4).
-Accepted to the ACGME MD Anderson Clinical Radiation Oncology Program.
-Academically gifted physician trainees desiring a focal clinical research development term, and commitment to formal K01/K08/K12/K23 award application by R25 term completion.
-Commitment to academic radiation oncology career
-Evidence of clinical and scholastic performance (USMLE, undergraduate medical GPA, recommendation letters, etc.)
-History of publication or prior research is favorable
-Commitment to 1-year post-clinical residency clinical research fellowship (i.e. 1 year of R25-supported focal research effort).
Mentor Matching:
This position reports to Clifton David Fuller, M.D., Ph.D. and Kristy K. Brock, Ph.D.
Dates or Training Schedule:
August 2020 through February 2021
Req #: 600661-202107181130
Job Title: Postdoctoral Fellow
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The primary purpose of the Postdoctoral Fellow is to assist the Principal Investigator and other Faculty members with scientific research projects. The primary activity of this position is academic research in association with a faculty member or team. A position is available immediately in the area of cancer immunology and translational research. The laboratory seeks to study therapy induced immune suppression and test drugs that can restore immunity and enhance immune responses with cancer therapies and translate those findings to the clinic in ongoing clinical trials. We are interested in studying immunologic mechanisms that confer response through various drugs that can act in tissue or bone marrow using various in vitro and in vivo tumor models.
Learning Objectives:
- Perform technical laboratory duties, techniques, in vivo and in vitro experiments studying immune biology in the context of cytotoxic cancer therapies and response to treatments including immunotherapy and/or radiotherapy.
- Projects will include using mouse tumor models to assess immunologic effects of cancer therapy induced immune suppression on tumor biology and drugs or cytokines that could reverse this effect in tumor bearing animals; small animal image-guided radiotherapy; tissue harvesting and microscopy; in vivo and ex vivo immunological assays; single cell sequencing methods and/or single cell cytokine analysis; implementation/development of novel protocols and procedures; execution of experiments; analysis of results.
- Familiarity with histology, animal husbandry, in vivo surgical techniques, immune and proteomic or transcriptomic assays is preferred. Ideal candidates would possess experience in molecular biology, cell culture, and animal models of human cancer.
- Training and supervising other research personnel on techniques and equipment procedures
- Maintenance of laboratory safety procedures and records and facilities
- Collect, analyze, plot data using appropriate software applications, store and record data on computer and lab notebooks
- Assist in writing of scientific papers for publication, grant applications and presentations at scientific meetings
- Other duties as assigned
Eligibility Requirements:
Education Required: Ph.D. or equivalent doctorate
Experience Required: At least 4 years of experience in scientific or experimental research work
Preferred: With preferred degree, with at least four years of required experience and proven scholarship in peer-reviewed publications as a first author and presentations at major meetings.
Mentor Matching:
This position reports to Steven H. Lin. See Dr. Lin's research profile.
Req #: 600661-202107181110
Job Title: Postdoctoral Fellow
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The primary purpose of the Postdoctoral Fellow is to assist the Principal Investigator and other Faculty members with scientific research projects. The primary activity of this position is academic research. A position is available immediately in the area of cancer immunology and translational research. The laboratory seeks to study novel treatment strategies that can induce the anti-tumor immunity. We are interested in studying immunologic mechanisms that confer response through various drugs and bio-materials that can trigger the innate and adaptive immune response to inhibit the growth of tumor.
Learning Objectives:
- Perform technical laboratory duties, techniques, in vivo and in vitro experiments studying immune biology in the context of cancer therapies and response to treatments including immunotherapy and/or radiotherapy.
- Projects will include using mouse tumor models to assess immunologic effects of cancer therapy induced immune response; small animal image-guided radiotherapy; tissue harvesting and microscopy; in vivo and ex vivo immunological assays; implementation/development of novel protocols and procedures; execution of experiments; analysis of results.
- Familiarity with histology, animal husbandry, in vivo surgical techniques, flow cytometry, immune and proteomic or transcriptomic assays is preferred. Ideal candidates would possess experience in molecular biology, cell culture, and animal models of human cancer.
- Training and supervising other research personnel on techniques and equipment procedures
- Maintenance of laboratory safety procedures and records and facilities.
- Collect, analyze, plot data using appropriate software applications, store and record data on computer and lab notebooks
- Assist in writing of scientific papers for publication, grant applications and presentations at scientific meetings
- Other duties as assigned
Eligibility Requirements:
EDUCATION Required: Ph.D. or equivalent doctorate
EXPERIENCE Required: At least 4 years of experience in scientific or experimental research work Preferred: With preferred degree, with at least four years of required experience and proven scholarship in peer-reviewed publications as a first author and presentations at major meetings.
Mentor Matching:
This position reports to Steven H. Lin. See Dr. Lin's research profile.
Req #: 600661-202107181140
Job Title: Postdoctoral Fellow
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The primary purpose of the Postdoctoral Fellow is to assist the Principal Investigator and other Faculty members with scientific research projects. The primary activity of this position is academic research in association with a faculty member or team. A position is available immediately in the area of cancer immunology and translational research. The laboratory has identified a new immunotherapy target induced by radiation that appears to be expressed mutually exclusively with PD-L1 in tumors. While therapeutic antibody has already been developed against this novel target and we will soon start first-in-human clinical trials here at MD Anderson, the lab will conduct additional basic science and translational work on this target, focusing on unraveling the mechanisms of T-cell suppression, through a potential novel intracellular domain, and translating the potential of combining monoclonal antibody therapy and radiation in animal models. The research will be conducted in both syngeneic and humanized mouse tumor models and deep profiling of immunologic alterations within the tumor microenvironment.
Learning Objectives:
- Perform technical laboratory duties, techniques, in vivo and in vitro experiments studying immune biology in the context of cytotoxic cancer therapies and response to treatments including immunotherapy and/or radiotherapy.
- Projects will include using mouse tumor models to assess immunologic effects of cancer therapy-induced immune suppression on tumor biology and drugs or cytokines that could reverse this effect in tumor-bearing animals; small animal image-guided radiotherapy; tissue harvesting and microscopy; in vivo and ex vivo immunological assays; mass cytometry/CyTOF and data analysis; implementation/development of novel protocols and procedures; execution of experiments; analysis of results.
- Familiarity with histology, animal husbandry, in vivo surgical techniques, immune and proteomic or transcriptomic assays is preferred. Ideal candidates would possess experience in molecular biology, cell culture, and animal models of human cancer.
- Training and supervising other research personnel on techniques and equipment procedures
- Maintenance of laboratory safety procedures and records and facilities
- Collect, analyze, plot data using appropriate software applications, store and record data on computer and lab notebooks
- Assist in writing of scientific papers for publication, grant applications and presentations at scientific meetings
- Other duties as assigned
Eligibility Requirements:
EDUCATION
Required: Ph.D. or equivalent doctorate
EXPERIENCE
Required: At least 4 years of experience in scientific or experimental research work
Preferred: With preferred degree, with at least four years of required experience and proven scholarship in peer-reviewed publications as a first author and presentations at major meetings.
Mentor Matching:
This position reports to Steven H. Lin. See Dr. Lin's research profile.
Req #: 600661-202107181150
Job Title: Postdoctoral Fellow
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The primary purpose of the Postdoctoral Fellow is to assist the Principal Investigator and other Faculty members with scientific research projects. The primary activity of this position is academic research in association with a faculty member or team. An opening currently exists with a examining the role of microRNAs in head and neck cancer, animal models of tumorigenesis and immune responses against head and neck and metastasis in head and neck cancer.
Learning Objectives:
KEY FUNCTIONS
1.) Perform technical laboratory duties, techniques, in vivo, in silico and in vitro experiments studying head and neck cancer and response to treatments including immunotherapy and/or radiotherapy.
2.) Projects may include generation of imaging files, image segmentation, image processing, dosimetric analyses, machine learning, toxicity assessment, clinical data review and/or dental science components.
3.) Familiarity with anatomy, statistics, medical physics, computational science and/or related fields is preferred. Ideal candidates would possess experience in informatics, models of human cancer.
4.) Training and supervising other research personnel on techniques and equipment procedures
5.) Maintenance of laboratory safety procedures and records and facilities
6.) Collect, analyze, plot data using appropriate software applications, store and record data on computer and lab notebooks
6.) Assist in writing of scientific papers for publication, grant applications and presentations at scientific meetings
7.) Other duties as assigned
Eligibility Requirements:
EDUCATION
Required: MD, PhD or equivalent doctorate
EXPERIENCE
Required: Experience in scientific or experimental research work doctoral degree
Preferred: With preferred degree, two or more years of required experience
Mentor Matching:
This position reports to Clifton David Fuller, M.D., Ph.D.
Req #: 600661-202108301131
Job Title: Postdoctoral Fellow
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The primary purpose of the Postdoctoral Fellow is to assist the Principal Investigator and other Faculty members with scientific research projects. The primary activity of this position is academic research in association with a faculty member or team. An opening currently exists with a examining the role of quantitative imaging and 3D printing for cancer applications, including radiation therapy and early detection of cancer.
Learning Objectives:
- Perform imaging studies, including segmentation and quantitative feature extraction.
- Projects may include generation of new programs for image analyses and 3D printing.
- Familiarity with clinical research in terms of reviewing patient charts.
- Training and supervising other research personnel on techniques and equipment procedures
- Maintenance of laboratory safety procedures and records and facilities
- Collect, analyze, plot data using appropriate software applications, store and record data on computer and lab notebooks
- Assist in writing of scientific papers for publication, grant applications and presentations at scientific meetings
- Other duties as assigned
Eligibility Requirements:
EDUCATION
Required: Ph.D. or equivalent doctorate
EXPERIENCE
Required: Three years of experience in scientific or experimental research work
Preferred: With preferred degree, four years of required experience
Mentor Matching:
This position reports to Eugene Koay, M.D., Ph.D. View Dr. Koay's research profile.
Req #: 600661-202109221202
Job Title: Postdoctoral Fellow
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A postdoctoral position is available studying the mechanisms of anti-tumor immune responses, in order to help shape clinical strategy for solid tumors in the laboratory of James Welsh, MD, Associate Professor of the Dept. of Radiation Oncology at the University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested in the combination of different immunotherapy strategies with radiation to enhance the abscopal effect, a phenomenon of tumor regression outside of the radiation field, as well as overcoming anti-PD1/PDL1 resistance using existing and novel therapies. We work closely with many of the top immunotherapy companies as such this work will provide the foundation for novel clinical trials. Additionally, there is significant opportunity for translation work, since we run both trials as well as a laboratory. This unique position allows for the opportunity to discovery new intellectual property and the satisfaction of having your work affect patient care within a short period of time. Applicants are encouraged to apply and provide three professional references.
Learning Objectives:
- Enthusiastic, highly self-motivated candidate, with the ability to function independently
- A strong background in immunology
- Someone who can think big and wants to make significant changes to the current state of oncology
- Prior experience with studies involving mice is preferred
- Command of written and spoken English language
- Prior publication record
Eligibility Requirements:
Applications are invited from qualified individuals, interested in working in a translational research lab. Preferred candidate should have less than 2 years of prior postdoctoral experience with background in mouse models studying immunology, cancer biology, cell biology or molecular biology and be highly motivated to pursue a career in biomedical research.
Mentor Matching:
This position reports to James Welsh, M.D. View Dr. Welsh's research profile.
Req #: 600661-202109301417
Job Title: Postdoctoral Fellow
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The Visiting Postdoctoral Fellow will develop and perform various scientific research projects in radiation oncology, including but not limited to the development and characterization of time-dose in silico optimization strategies for multiple organ-at-risk normal tissue toxicity reduction using a static dose profile to reduce xerostomia, dysphagia, and osteoradionecrosis risk. Additionally, research work will entail the development of time-dose in silico (re) optimization strategies for multiple organ-at-risk normal tissue toxcicity reduction using an adaptive dose profile and will determine late effects of radiotherapy through analysis of MR-LinAC data, in silico implementation of adaptive radiotherapy by incorporating image-base biomarkers for xerostomia, dysphagia, and osteoradionecrosis.
Learning Objectives:
The Visiting Postdoctoral Fellow will extract parameter values from multiparametric MRI's using deep learning-based recognition. In addition, the Visiting Postdoctoral fellow will develop statistical models to determine the optimal temporally feathered radiotherapy base model using homogenous repair time for all organs-at-risk. Additionally, the visiting postdoctoral fellow will utilize statistical and deep-learning models to guide adaptive radiation plans for toxicity reduction and will characterize normal tissue complications after radiation therapy for head and neck cancer.
Eligibility Requirements:
Successful applicants must have a PhD (biomedical sciences, biomedical engineering, or equivalent discipline) and/or a MD degree with less than two years of postdoctoral experience and must have a high level or written and oral communication skills in English to be professionally competent.
Stipend:
This is an unpaid Visiting Postdoc Position.
Mentor Matching:
This position reports to Clifton David Fuller, M.D., Ph.D.
Req #: 600661-202111101809
Job Title: Postdoctoral Fellow
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This is a three-year training program. During the first six weeks of the program, fellows will interview with faculty on our mentoring committee to select a mentor and lab of their choosing. Once a mentor is selected and a research project is identified, the fellow will work with his/her mentor to identify additional committee members to guide them in their research and training. Fellows will participate in a series of didactic course work offered at MD Anderson UT Health Graduate School (GSBS) and strategically matched clinical rotations, while pursuing research in a basic or translational research laboratory. The TRIUMPH postdoc will earn a certificate upon successful completion of the program.
Learning Objectives:
Identification of a mentoring committee to help guide his research, identification and completion of applicable coursework at GSBS, attendance at monthly journal club, routine committee meetings, particpation and completion of applicable clinical rotations.
Eligibility Requirements:
Ph.D. in the life or natural sciences. Desire to pursue translational research. Successful completion of Ph.D or M.D./Ph.D. At least one first or co-first author publicatio in a high impact journal.
Mentor Matching:
This position reports to Eugene Koay, M.D., Ph.D. View Dr. Koay's research profile.
Radiation Physics
Req #: 600662-202108051642
Job Title: Postdoctoral Fellow
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This postdoctoral fellow position is to work on a large research project to create tools to support the peer review process in radiation oncology. This position specifically will focus on toxicity predictions, helping create tools that predict the relative likelihood of various acute toxicities based on the radiotherapy treatment plan. This is be for a full range of cancer types, and the candidate can expect to work with radiotherapy clinical and research teams.
Learning Objectives:
- How to curate and understand radiation therapy treatment plans, including dose distributions and contours
2. How to interpret treatment-related toxicity data
3. How to create mathematical models relating the treatment plan and patient outcomes (focusing on acute toxicity)
Eligibility Requirements:
PhD in a physical science
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Laurence Court, Ph.D.
Stipend:
Stipend support will follow the NIH NRSA level for the appropriate PGY.
Req #: 600662-202108051639
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Sawakuchi and Shaitelman lab at the University of Texas MD Anderson Cancer Center. The research projects involve investigations in the role of radiation and DNA repair defects on immune response activation and radiosensitization. Particularly, the postdoctoral fellow will contribute to the discovery and translation of biological pathways to: 1) predict tumor response to radiation using DNA repair defects; and 2) activate the immune system using radiation in combination with DNA repair defects.
Learning Objectives:
The postdoctoral fellow will learn the field of translational radiation oncology. Particularly, the trainee will learn how to apply principles and assays used in radiobiology, DNA repair and immunology to translate preclinical findings into clinical trials. The trainee will also have the opportunity to train in mentorship and leadership skills towards becoming an independent researcher.
Eligibility Requirements:
Ideal candidates should have finished their Ph.D., or M.D. degrees in radiobiology, immunology, bioinformatics, biology, biochemistry, biomedical sciences, or similar research fields. Experience with small animal handling, immunology and DNA damage assays is highly desired but not a requirement. Good verbal and written communication skills are also important. The individual is expected to work within a large group of motivated interdisciplinary researchers including clinicians, postdoctoral fellows and other research staff.
Program Start Date:
Starting as earlier as October 1, 2021 for two years.
Mentor Matching:
The position reports to Gabriel Sawakuchi, Ph.D.
Stipend:
Stipend support will follow the NIH NRSA level for the appropriate PGY.
Req #: 600662-202107181130
Job Title: Postdoctoral Fellow
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Research into applications of deep learning and radiomics to understand patient outcomes. The fellow will help develop software tools for analyzing images and predicting outcomes. We will focus specifically on understanding how images can be used to support clinical decision making for patients with metastatic brain lesions.
Learning Objectives:
1. Learn how radiomics and deep learning can be applied to problems in radiation oncology
2. Learn how to investigate the impact of image quality on image analysis tasks
3. Learn about radiation oncology and medical physics in general, including how artificial intelligence can be applied to improve these fields and patient outcomes.
Eligibility Requirements:
The ideal candidates should have finished (or be about to finish) their Ph.D. degrees in medical physics, computer science, physics, engineering or applied mathematics. Programming skills in Python and/or C++/C# is required. The individual is expected to work within a large group of motivated interdisciplinary professionals.
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Laurence Court, Ph.D., (primary), Carlos Cardenas, Ph.D., (deep learning), and Jinzhong Yang, Ph.D., (deformable image registration and auto-contouring).
Additional application information:
More information on our research group can be found at rpa.mdanderson.org.
Req #: 600662-202107181135
Job Title: Postdoctoral Fellow
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The fellow will develop deep-learning-based algorithms and tools for various applications in proton radiation therapy, such as fast dose prediction, plan robustness evaluation and optimization, auto segmentation and radiomics based on dual-energy CT, etc.
Learning Objectives:
1. Learn how deep learning can be used for problems in proton radiation therapy.
2. Learn how to apply mathematical knowledge and skills to medical problems.
3. Learn about radiation oncology and medical physics in general.
Eligibility Requirements:
The ideal candidates should have finished (or be about to finish) their Ph.D. degrees in medical physics, computer science, physics, engineering or applied mathematics. Programming skills in Python and/or C++/C# is required.
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Dr. Ming Yang.
Req #: 600662-202107181110
Job Title: Postdoctoral Fellow
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Research into applications of FLASH RT. Fellow will develop and commission FLASH beam lines, develop detectors and dosimetry protocols, and be involved in developing shielding and irradiation setups for animal irradiations.
Learning Objectives:
1. Learn how to establish FLASH beam lines and the requirements of the dosimetry.
2. Develop detectors of FLASH RT
3. Developing irradiation setups for animal irradiations
Eligibility Requirements:
The ideal candidates should have finished (or be about to finish) their Ph.D. degrees in medical physics, physics, engineering or similar. The individual is expected to work within a large group of motivated interdisciplinary professionals.
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Dr. Emil Schueler.
Req #: 600662-202107181140
Job Title: Postdoctoral Fellow
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Assists principal investigator with clinical, translational, and basic scientific
Learning Objectives:aims of our CRC Moon Shot and Astellas project. Mouse tumor, human tumor and PDX mouse model samples are to be analyzed for protein and molecular profiling to assess the impact of target metastatic site resident immune cells, immune infiltrates and mechanisms of CRC minimal residual disease (MRD). Functions in a separate and independent manner in the design and initiation of research experiments. Designs, develops or adapts equipment used in experiments or research to obtain desired results. Determines specific goals or objectives to be obtained, evaluates research data and develops and revises techniques or approaches to work problems. Interfaces with the electronic medical record, and databases of tissue samples blood cytokines and protein biomarkers analysis and tumor molecular data.
Compiles, writes and submits project results for publications. Writes grant applications independently and assists principal investigator with grant applications.
Additionally,
a. Applicant should have experience in methods of sensitive detection of proteins and also work on developing assays and CyTOF and multiplex panels that can distinguish determine the impact of resident immunity, immune infiltrates and mechanisms involved in CRC-MRD.
b. Interpret, present and report research findings at internal meetings and potentially external scientific conferences.
Learning Objectives:
- understanding of biology of CRC-MRD and microenvironment interactions and predictors of outcome
- ability to search and evaluate clinical and scientific literature
- ability to form and then defend hypotheses based on prior clinical or experimental data
- ability to effectively communicate findings in written and oral form
- ability to write persuasive grant applications and scientific publications
Eligibility Requirements:
Graduate degree in verterinary medicine, science, or chemistry fields
Program Start Date:
Anticipated start date 12/14/2020, average 40 hours per week is needed to accomplish goals
Mentor Matching:
David Menter, Ph.D., Assistant Professor of GI Medical Oncology; Scott Kopetz, MD, PhD. Professor of GI Medical Oncology; Natalie Fowlkes, DVM, Ph.D: Assistant Professor of Veterinary Medicine.
Req #: 600662-202107181145
Job Title: Postdoctoral Fellow
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Development of evaluation metrics for radiation therapy treatment plans based on patient outcomes. We will develop an evaluation methodology that quantifies the probability of a particular patient outcome based on the patient's radiation therapy treatment plan. The resulting metric will then be used to develop a scoring system for patient plans.
Learning Objectives:
1. Learn how to correlate patient outcomes to radiation therapy treatment plans.
2. Learn how to create probability density functions that converts a planned radiation therapy dose into a probability for a particular patient outcome.
3. Learn about radiation oncology and medical physics in general.
Eligibility Requirements:
The ideal candidates should have finished (or be about to finish) their Ph.D. degree in medical physics, computer science, physics, engineering or applied mathematics. Programming skills in Python, R and/or C# is required. The individual is
expected to work within a large group of motivated interdisciplinary professionals.
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Dr. Thomas Whitaker and Dr. Laurence Court.
Req #: 600662-202107181155
Job Title: Postdoctoral Fellow
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The Lin/Schueler research lab in the Department of Radiation Oncology/Physics at UT MD Anderson Cancer Center is seeking a postdoctoral fellow. Our focus is on developing the foundation for a clinical translation of FLASH radiation therapy (RT). Current focus of interest is on hematological and gastrointestinal toxicity and how they relate to dose rate. A large focus is also on the immunological effects of FLASH and how combination treatments can further increase the therapeutic window of FLASH RT. More information on the position can be found at https://www.postdocjobs.com/posting/7071940
Learning Objectives:
1. Gain insight into the biological effects of FLASH RT
2. Elucidate the dependence of the physical beam irradiation parameters on the FLASH effect on multiple organ systems
3. Developing irradiation setups for animal irradiations
Eligibility Requirements:
Ideal candidates should have experience in cancer biology and immunology. Excellent verbal and written communication skills are required. The individual is expected to work within a large group of motivated interdisciplinary researchers including clinicians, postdoctoral fellows and other research staff.
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Dr. Emil Schueler.
Req #: 600662-202107181115
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Sawakuchi and Shaitelman lab at the University of Texas MD Anderson Cancer Center. The research projects involve investigations in the role of radiation and DNA repair defects on immune response activation and radiosensitization. Particularly, the postdoctoral fellow will contribute to the discovery and translation of biological pathways to: 1) predict tumor response to radiation using DNA repair defects; and 2) activate the immune system using radiation in combination with DNA repair defects.
Learning Objectives:
The postdoctoral fellow will learn the field of translational radiation oncology. Particularly, the trainee will learn how to apply principles and assays used in radiobiology, DNA repair and immunology to translate preclinical findings into clinical trials. The trainee will also have the opportunity to train in mentorship and leadership skills towards becoming an independent researcher.
Eligibility Requirements:
Ideal candidates should have finished their Ph.D., or M.D. degrees in radiobiology, immunology, bioinformatics, biology, biochemistry, biomedical sciences, or similar research fields. Experience with small animal handling, immunology and DNA damage assays is highly desired but not a requirement. Good verbal and written communication skills are also important. The individual is expected to work within a large group of motivated interdisciplinary researchers including clinicians, postdoctoral fellows and other research staff.
Dates or Training Schedule:
Anticipated start date June 14,2021. This position will be for two years.
Mentor Matching:
The postdoctoral fellow will be mentored by Gabriel Sawakuchi, Ph.D.
Additional Application Information:
Visit Dr. Sawakuchi's page for more information about their lab and research.
Req #: 600662-202107181120
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Sawakuchi and Shaitelman lab at the University of Texas MD Anderson Cancer Center. The research project involves investigations in the role of radiation and DNA repair defects on immune response activation and radiosensitization. Particularly, the postdoctoral fellow will contribute to the discovery and translation of biological pathways to activate the immune system using radiation in combination with DNA repair drugs and immune checkpoint blockade. The postdoctoral fellow will work in a multidisciplinary team to study the mechanisms by which the combination of radiation, ATR or PARP inhibitors and immune checkpoint blockade modulates sustained immune responses.
Learning Objectives:
The postdoctoral fellow will learn the field of translational radiation oncology. Particularly, the trainee will learn how to apply principles and assays used in radiobiology, DNA repair and immunology to translate preclinical findings into clinical trials. The trainee will also have the opportunity to train in mentorship and leadership skills towards becoming an independent researcher.
Eligibility Requirements:
Ideal candidates should have finished their Ph.D., or M.D. degrees in radiobiology, immunology, biology, biochemistry, biomedical sciences, or similar research fields. Experience with small animal handling, immunology and DNA damage assays is highly desired but not a requirement. Good verbal and written communication skills are also important. The individual is expected to work within a large group of motivated interdisciplinary researchers including clinicians, postdoctoral fellows and other research staff.
Dates or Training Schedule:
Starting as early as possible for two years.
Mentor Matching:
The postdoctoral fellow will be mentored by Gabriel Sawakuchi, Ph.D.
Additional Application Information:
Visit Dr. Sawakuchi's page for more information about their lab and research.
Req #: 600662-202107181125
Job Title: Postdoctoral Fellow
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A postdoctoral fellowship position is immediately available in the Department of Radiation Physics. The appointed postdoctoral fellow will work on an NIH-funded project to investigate gold nanoparticle-mediated radiosensitization strategies for radiation therapy.
Learning Objectives:
1. Nanoscale cellular imaging technique
2. AI/Machine learning for nanoscale cellular image analysis
3. Monte Carlo simulations with nanoscale cellular models
Eligibility Requirements:
Ph.D. degree in physics, medical physics, engineering, or other related disciplines. Experience in Monte Carlo modeling with the Geant4 toolkit or similar code systems is highly desired. Computer programming skill in C++ and/or Python is required. Experience in machine learning platform (e.g., TensorFlow) and/or wet lab work (e.g., clonogenic assay) is a plus.
Dates or Training Schedule:
Starting as early as possible for up to five years as postdoc at MD Anderson or six years combination with other institutions
Mentor Matching:
The postdoctoral fellow will be mentored by Sang Hyun Cho, Ph.D. View Dr. Cho's research profile.
Req #: 600662-202108091643
Job Title: Postdoctoral Fellow
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This postdoctoral fellow position is to work on a large research project to create tools to support the peer review process in radiation oncology. This position specifically will focus on toxicity predictions, helping create tools that predict the relative likelihood of various acute toxicities based on the radiotherapy treatment plan. This is be for a full range of cancer types, and the candidate can expect to work with radiotherapy clinical and research teams.
Learning Objectives:
1. How to curate and understand radiation therapy treatment plans, including dose distributions and contours
2. How to interpret treatment-related toxicity data
3. How to create mathematical models relating the treatment plan and patient outcomes (focusing on acute toxicity)
Eligibility Requirements:
Ph.D. in a physical science
Program Start Date:
This position will start as soon as a suitable candidate is able to start.
Mentor Matching:
The position reports to Laurence Court, Ph.D.
Req #: 600662-202111091809
Job Title: Postdoctoral Fellow
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The research labs of Dr Sam Beddar and Dr. Emil Schueler in the Department of Radiation Physics at UT MD Anderson Cancer Center is seeking a postdoctoral fellow. Our focus is on developing technical solutions for FLASH radiation therapy (RT), to implement those solutions to gain insight into the biological effects of FLASH RT, and to pave the way for clinical translation. Current focus of interest is on the development of stable irradiation platforms, new detectors, and new dosimetry protocols for FLASH RT based on scintillator detector technology. Successful applicants would be part of an established, well-funded, committed, and productive interdisciplinary research team.
Learning Objectives:
- to learn to develop technical tools for FLASH RT
- to learn to develop novel dosimeters and dosimetry protocols
- to learn t document, analyzes, and maintains research data
- to learn to mentor, students and/or trains junior research team members
- to learn writing manuscripts and presents research findings at conferences
Eligibility Requirements:
Candidates for this position must have a Ph.D. in electrical or optical engineering, medical physics, physics, or a closely related physical science. Successful applicants must be highly motivated, independent, and must have experience with scientific computer programming (C/C++, Matlab, Python). Excellent verbal and written communication skills are required. Experience with 3D printing design, radiation physics, and radiation measurements are a plus. The individual is expected to work within a large group of motivated interdisciplinary researchers including clinicians, postdoctoral fellows and other research staff.
Program Start Date:
This position is for 1 year, renewable.
Mentor Matching:
The position reports to Sam Beddar, Ph.D. View Dr. Beddar's research profile.
Stem Cell Transplantation
Req #: 600379-202107181110
Job Title: Postdoctoral Fellow
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Postdoctoral research fellowship program is primary focusing on clinical training and conducting clinical researches in the field of stem cell transplantation and cellular therapy. The position is designed to provide the experience needed to perform hematopoietic cell transplant to treat patients with benign and malignant hematologic diseases as well as conduct and publish transplant-related prospective and retrospective researches. The fellow will work under supervision of Dr. Samer A. Srour and may collaborate with other faculties in the Department of Stem Cell Transplant and Cellular Therapy.
Learning Objectives:
1. Fellow will learn the processes of hematopoietic stem cell transplantation including pre-transplant patient evaluation, donor selection, mobilization and stem cell collection/apheresis, transplant procedure planning and performing, and spectrum and management of posttranspant complications.
2. Fellow will learn the processes of conducting researches in the field of hematopoietic cell transplant including data management, statistical analysis, manuscript writing and publishing research articles.
Eligibility Requirements:
Appointee must have received a Ph.D. or M.D., completed hematology training and must have at least 1 year prior experience in clinical hematology patient cares.
Dates or Training Schedule:
October 2020 through October 2023
Mentor Matching:
This position reports to Samer A. Srour, M.B.
Surgical Oncology
No positions are currently available in this department. Check back later for new opportunities.
Symptom Research
Req #: 600659-202107181110
Job Title: Postdoctoral Fellow
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The Grace lab is seeking an enthusiastic Postdoctoral Researcher to study how brain glia contribute to affective and cognitive disturbances that are co-morbid with high-impact chronic pain. This project involves complex behavioral measures of depression and motivation in models of neuropathic pain, stereotaxic surgeries, transgenic mouse strains, super-resolution microscopy, single-cell and next-generation RNA sequencing, and other biochemical techniques.
The applicant will join the Laboratories of Neuroimmunology, comprising the research teams of five collaborating Principal Investigators who aim at understanding chronic pain, cognitive deficits and fatigue in response to cancer and its treatment. The post-doctoral fellow will work under direct supervision of a Principal Investigator.
We highly value innovation, learning, hard work, creativity and an interactive, respectful and fun atmosphere. If you are interested in helping to understand the molecular and cellular mechanisms of pain and developing novel interventions to help improve the quality of life for people suffering from chronic pain in an internationally-renowned, well-funded group of scientists using a highly integrated and interdisciplinary approach in the number one cancer center in the USA, we are the perfect environment for you!
A PhD in neuroscience, immunology, or related disciplines is required. Experience in working with rodents and a background in pain or immunology is preferred.
ESSENTIAL FUNCTIONS
Research Activity
Nerve injury and stereotaxic surgeries in mice
Behavioral measures of pain, and affective and cognitive disturbances in mice
Immunohistochemistry and microscopy studies on cells and nervous system tissues
Single-cell and bulk RNA-seq
Western blotting and qPCR
Luciferase assays and immunoassays
Collect and process ex vivo biological samples including brain and spinal cord
Present results in departmental and national meetings
Prepare and write manuscripts for publication.
2. Interpersonal Skills, Communication, Learning Skills
Strong written and oral communication skills
Communication with faculty and staff within and outside the laboratory.
Ability to work with others in a highly collaborative manner.
Good problem-solving abilities.
3. Other
Responsible for monitoring laboratory equipment and implementing safety procedures.
Strong interest in basic and translational research
Supervision of 1-2 research assistants
Learning Objectives:
Applicants will gain experience of preclinical research methods, with an emphasis on understanding behavioral testing inmodels of neuropathic pain. They will become proficient with basic biochemical techniques employed in preclinicalneuroimmunology research and develop advanced skills in the organization, presentation, and analysis of data.
Eligibility Requirements:
A Ph.D. in neuroscience, immunology, or related disciplines is required. Experience in working with rodents and a background in pain or immunology is preferred.
Mentor Matching:
The position reports to Peter Grace, Ph.D.
Req #: 600659-202109221000
Job Title: Postdoctoral Fellow
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We are looking for a post-doctoral researcher with a strong background in neuroscience to join the Laboratories of Neuroimmunology at MD Anderson Cancer Center. Applicants should hold (or soon receive) a Ph.D. in neuroscience or a related discipline. The research project will use mouse models of cancer to explore the mechanistic underpinnings of paraneoplastic neurological syndromes. Experience working with rodents and a background in neuroscience, pain research and/or immunology is preferred. The position is available February 1, 2022, though the actual start date is flexible.
Research Activity:
Immunohistochemistry and microscopy studies on nervous system, muscle and other tissues.
Behavioral assays of physical activity and pain in mice.
Work with genetically modified mice.
Live-cell imaging of neuronal/immune cell physiology.
Isolate and run biochemical experiments on protein & RNA isolated from mouse tissues.
Perform pharmacological manipulations in vivo.
Prepare and write manuscripts for publication.
Interpersonal Skills, Communication, Learning Skills:
Strong written and oral communication skills.
Communication with faculty and staff within and outside the laboratory.
Ability to work with others in a highly collaborative manner.
Good problem-solving abilities.
Other Duties:
Responsible for monitoring laboratory equipment and implementing safety procedures.
Strong interest in basic and translational research.
Supervision of research assistants.
Learning Objectives:
Postdoctoral fellow will gain skills in :
1. Immunohistochemistry and microscopy studies on nervous system, muscle and other tissues, behavioral assays of pain in rodents, live-cell imaging of neuronal/immune cell physiology.
2. Writing manuscripts and publications
3. Presenting during lab meetind and National conferences
Eligibility Requirements:
Applicants should hold (or soon receive) a Ph.D. in neuroscience or a related discipline. Experience with rodent behavioral testing is preferred but not required. Successful applicants should be highly self-motivated, have outstanding experimental skills, and be able to think independently but also work well in a team.
Mentor Matching:
The position reports to Andrew Shepherd, Ph.D. View Dr. Shepherd's research profile.
Req #: 600659-202109301420
Job Title: Postdoctoral Fellow
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We are looking for a post-doctoral researcher with a strong interest in the neuroimmune mechanisms underlying the development of chronic pain to join the research team of Drs. Annemieke Kavelaars and Cobi J. Heijnen, laboratories of Neuroimmunology, MD Anderson Cancer Center Pain Research Consortium. The project is funded by an NIH RO1 grant in the context of the HEAL initiative and seeks to understand the mechanisms via which a fibroblast derived protein controls the transition to chronic pain. Experience in working with rodents and a background in neuroscience, pain research and/or immunology is preferred. Applicants should hold (or soon receive) a Ph.D. in neuroscience, Immunology, or a related discipline. Experience with rodent behavioral testing is preferred but not required. Successful applicants should be highly self-motivated, have outstanding experimental skills, and be able to think independently but also work well in a team. We offer an international team of highly motivated researchers who work together to understand mechanisms underlying chronic pain and identify novel targets for treatment.
Learning Objectives:
Applicants will gain experience in preclinical research methods to study pain in murine models of chronic neuropathic and inflammatory pain. They will become proficient in biochemical and immunological techniques employed in preclinical neuroimmunology research. They will be trained to develop research projects, analyze data, and present their findings in presentations and papers. They will be challenged to strengthen their scientific thinking and supported in writing applications for funding.
Eligibility Requirements:
Applicants should hold (or soon receive) a Ph.D. in neuroscience or a related discipline. Successful applicants should be highly self-motivated, have outstanding experimental skills, and be able to think independently but also work well in a team.
Mentor Matching:
The position reports to Annemieke Kavelaars, Ph.D. View Dr. Kavelaars' research profile.
Req #: 600659-202201141827
Job Title: Postdoctoral Fellow
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We are looking for a post-doctoral researcher with a background in neuroscience to join the Laboratories of Neuroimmunology at MD Anderson Cancer Center. Applicants should hold (or soon receive) a Ph.D. in neuroscience or a related discipline. The research project will use mouse models to explore the interactions between neurons and cancer. Experience working with rodents and a background in neuroscience is preferred. The position is available February 1, 2022, though the actual start date is flexible.
Learning Objectives:
Gain understanding of neuronal regulation of cancer. Develop advanced skills in the organization, presentation, data analysis, and writing. Learn skills to address questions related to the crosstalk among neuron, cancer, and glia. The Postdoctoral Fellow will lead work focused on cell and mouse studies that address the role of neurons and glia in various cancer models. They will work with genetically modified mice, primary mouse neuron and glia culture, cancer cell lines, biochemical assays on protein & DNA/RNA, immunohistochemistry, microscopy, pharmacological manipulations in vitro and in vivo, mouse neuromodulatory and behavioral assays, and prepare and write manuscripts for publication. The Postdoctoral fellow will become proficient with basic cellular, molecular, biochemical, and histological techniques employed in preclinical cancer neuroscience research.
Eligibility Requirements:
Completed Ph.D. in neuroscience or a related discipline. Experience with rodent experiments is preferred. Successful applicants should be highly self-motivated, have outstanding experimental and communication skills, have good work ethic and scholar integrity, and be able to think independently but also work well in a team.
Mentor Matching:
The position reports to Peter Grace, Ph.D.
Systems Biology
Req #: 412100-202201111557
Job Title: Postdoctoral Fellow
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Postdoctoral positions are available in the Lin lab in the Department of Systems Biology at The University of Texas MD Anderson Cancer Center. Our laboratory focuses on utilizing systems approaches to identify key therapeutic vulnerabilities associated with deficiencies in DNA damage response, and develop novel personalized cancer therapies based on these deficiencies in cancer (McGrail, et al. Science Translational Medicine 2021; McGrail, et al. Cancer Cell 2020; Sun, et al. Cancer Cell 2018; Peng, et al. Nat. Comm. 2014). The candidates will also have opportunities to develop highly impactful projects based on their research interests.
Learning Objectives:
1. Deepen the understanding of cancer development.
2. Advancing Cancer Research.
3. Translating scientific discoveries to therapeutic benefits for patients with cancer.
Eligibility Requirements:
Candidates should have a PhD degree or equivalent. We are seeking highly motivated candidates with experience in cancer biology, cancer immunology, and/or bioinformatics to work on two recently funded R01 grants focused on leveraging DNA replication stress response to treat cancer and enhance tumor immunogenicity.
Successful experimentally focused postdocs will have experience with standard molecular biology techniques and in vivo mouse experiments. Successful computationally focused postdocs will be able to integrate diverse "-omics" datasets and patient clinical information, including experience with standard languages (e.g., Python, R).
All applicants should have strong communication skills and experience preparing scientific manuscripts.
Program Dates:
February 2022, 40-hour workweek.
Mentor Matching:
The position reports to Shiaw-Yih Lin, Ph.D. View Dr. Lin's research profile.
Additional Application Information:
All applicants should have strong communication skills and experience preparing scientific manuscripts. Interested applicants should send a cover letter describing your previous experience and future research plans along with a detailed CV and at least three references to:
Shiaw-Yih (Phoebus) Lin, Ph.D.
Professor, Deputy Chair
Chief, Section of Translational and Systems DNA Repair
The University of Texas MD Anderson Cancer Center
Department of Systems Biology, Unit 1058
Zayed Building
P. O. Box 301439
Houston, TX 77230-1439
E-mail: sylin@mdanderson.org
Thoracic & Cardiovascular Surgery
Req #: 600386-202201061831
Job Title: Postdoctoral Fellow
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A postdoctoral position is available in the laboratory of Yonathan Lissanu Deribe, M.D, Ph.D., in the Department of Genomic Medicine and Department of Thoracic Surgery at The University of Texas MD Anderson Cancer Center. Our laboratory focuses on identification of cancer vulnerabilities, and discovery of novel therapeutics by leveraging our understanding of chromatin biology in cancer development (Lissanu Deribe et al Nature Medicine 2018, Lissanu Deribe et al PNAS 2016).
https://www.mdanderson.org/research/departments-labs-institutes/labs/lissanu-laboratory.html
To this end, we utilize genetically engineered mouse (GEM) models of cancer, various functional genomic approaches including genome-wide CRISPR knockout screens, immunological and epigenomic technologies such as RNA- Seq, ChIP-Seq and ATAC-Seq.
We plan to expand our efforts in identifying novel therapeutic targets in genetically defined tumors. Recently, we have discovered and patented novel proteolysis targeting chimeric molecules (PROTACs) that induce selective degradation of oncoproteins and received several grants to further develop these molecules as cancer therapeutics. (https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019200217). Excitingly, some of our chemical probes have synergistic anti-tumor efficacy in combination with immunotherapy.
The position will provide deep exposure and training in cancer functional genomics, chromatin biology, cancer immunology and cancer drug discovery.
We seek highly motivated individuals with a Ph.D. or equivalent degree in all areas of molecular & cell biology, biochemistry or genetics. Experience with hands on mice work, protein purification or computational biology is a big plus but not required.
The Lissanu laboratory is a well-funded lab situated in a highly dynamic and stimulatory environment for learning. MD Anderson Cancer Center is rated number one hospital in cancer care in the United States. The institute offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world's largest biomedical center. Competitive salary and benefits are provided to post-doctoral fellows. Houston is the fourth largest city in the USA with a vibrant and booming economy. Houston has a mild winters and is sunny year round.
Learning Objectives:
• Use cutting-edge approaches to seek novel therapeutic targets for human cancers
• Be responsible for the design and execution of experimental work, data analysis and write up
• Attend and present at internal and international meetings
• Be expected to publish data in top scientific journals
Eligibility Requirements:
• PhD or equivalent in Molecular Biology, Biochemistry, Immunology, Genetics or related field
• Good publication record
• Excellent communication skills is required.
Please send a cover letter, curriculum vitae, names and contact information of three references, and a brief summary of past research accomplishments and future research plans to: Yonathan Lissanu Deribe, M.D, Ph.D. (ylissanu@mdanderson.org)
Mentor Matching:
The position reports to Yonathan Lissanu Deribe, M.D., Ph.D. View Dr. Deribe's research profile.
Thoracic/Head and Neck Medical Oncology
Req #: 600657-202107181120
Job Title: Postdoctoral Fellow
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My research program is focused on developing new and more effective treatments for HPV+ cancers using a combination of radiation and immunotherapy, and associated response biomarkers. In particular, to improve the responsiveness of HPV+ cancers to immunotherapy, it is necessary to understand 1) if HPV-antigens are effective targets for CD8+ T cells, and if not; 2) if other cancer antigens may be targeted, and whether the latter are unique to or shared between patients; 3) the features of T cells that recognize HPV+ cancer-associated Ag; and 4) how to unlock superior T cell functions in HPV+ cancer patients.
To answer these questions, my lab employs a combination of multidisciplinary wet- and dry-lab based techniques. I strongly believe in team science, and I am building a lab in which scientists will be responsible for and learn from having one or several main projects, while also working together towards the lab's main goal.
Learning Objectives:
The position is designed to allow trainees to further develop their skills in immunological assays such as flow cytometry and sorting, functional T cell assays, and TCR engineering, as well as single cell sequencing (transcriptional, TCR, and cell surface stains), and bulk whole exome and RNA sequencing. The trainee will work in collaboration with other trainees and staff in the lab, as well as other labs and cores in the department and MD Anderson as a whole.
The trainee will also work on developing his/her grantsmanship skills.
Eligibility Requirements:
Individuals who have completed a Ph.D. and have training relevant to the position are eligible.
Dates of Training Schedule:
The position is immediately available.
Mentor Matching:
This position reports to Nils-Petter Rudqvist, Ph.D.
Req #: 600657-202107181130
Job Title: Postdoctoral Fellow
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The Kurie Laboratory in the Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, seeks to fill multiple postdoctoral positions. Our research focuses on the molecular mechanisms by which lung cancer cells generate a pro-metastatic tumor microenvironment, with three complementary areas of investigation: (1) a tumor cell-derived collagen modifying enzyme called lysyl hydroxylase 2 (LH2) that functions as a nodal regulator of fibrosis and immunosuppression; (2) Golgi-directed secretory processes driven by oncogene-induced transcriptional programs; and (3) epithelial-to-mesenchymal transition as a driver of fibrosis and immunosuppression in the tumor microenvironment.
Learning Objectives:
Postdoctoral fellows will benefit from training in model development and characterization, including 2- and 3-dimensional cell culture models and autochthonous and orthotopic mouse models that recapitulate features of the TME in human cancers, and translating those findings to clinically and molecularly annotated human tumor tissue banks. Fellows will have educational and mentoring opportunities (e.g., pilot funding, grant-writing courses, and teaching and mentoring experience in our summer undergraduate and graduate internship programs) and extensive opportunities to gain presentation skills at weekly Kurie lab meetings, monthly departmental joint lab meetings, monthly meetings for our programmatic research groups (NCI-funded SPORE, CPRIT-funded MIRA), and annual conferences (e.g., Keystone, Gordon, Cold Spring Harbor, AACR).
Eligibility Requirements:
Individuals who have completed a Ph.D and have training relevant to the position. Qualified individuals will demonstrate the potential for research as evidenced by their peer-reviewed publications and funding. Background in cancer biology and expertise in the design and execution of cell culture and in vivo experiments that incorporate a variety of molecular and cellular techniques is desirable.
Dates of Training Schedule:
The position is immediately available.
Mentor Matching:
This position reports to Jonathan M. Kurie, M.D.
Req #: 600657-202107181110
Job Title: Postdoctoral Fellow
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The Gibbons lab in the Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, seeks to fill multiple postdoctoral research positions. Our research focuses on the mechanisms by which lung cancer evades immune system surveillance and becomes invasive/metastatic. We investigate several complimentary areas, including: 1) the role of the tumor cells in reprogramming the tumor immune microenvironment, 2) tumor cell-extracellular matrix interactions, and 3) tumor intrinsic changes that facilitate tumor invasion and distant metastasis.
Learning Objectives:
Postdoctoral fellows will benefit from training in cancer biology, cancer immunology, the development &characterization of genetic models of lung cancer, use of 2- or 3-dimensional cell culture systems & characterization of the extracellular & tumor immune microenvironment. They will interact with bioinformatics & pathology collaborators to facilitate translation of their discoveries into human samples and datasets. They will have educational & mentoring opportunities (e.g., pilot grant funding, grant writing, mentoring experience with summer students & rotating graduate students), extensive opportunities to gain presentation skills at individual & joint lab meetings, departmental meetings, programmatic research groups (e.g., NCI-funded SPORE) & institutional symposia. They will have the opportunity to present their work at annual conferences such as the Keystone, AACR & Cold Spring Harbor Lab meetings.
Eligibility Requirements:
Individuals who have completed a Ph.D. and have training relevant to the position are eligible. Qualified applications will demonstrate the potential for research as evidenced by their peer-reviewed publications and funding. A background in cancer biology and expertise in the design and execution of cell culture and in vivo experiments that incorporate a variety of molecular/cellular techniques is desirable.
Dates or Training Schedule:
The position is available immediately.
Mentor Matching:
This position reports to Don Gibbons, M.D ,Ph.D. See Dr. Gibbons' research profile.
Req #: 600657-202108171711
Job Title: Postdoctoral Fellow
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A postdoctoral position is available in Dr. Renata Ferrarotto’s group in the Department of Thoracic Head and Neck Medical Oncology at The University of Texas MD Anderson Cancer Center, focusing on the immune and genomics landscape of head and neck cancer and the development of models systems and novel treatment regimens for salivary gland adenoid cystic carcinoma. By leveraging the unique samples and clinical data from Dr. Ferrarotto’s cutting-edge clinical trials, the appointed postdoctoral fellow will develop and use research methods involving immunology, cancer biology, genomics, in vivo disease models including PDX and humanized mice, and bioinformatics analysis to analyze trial patient samples, and develop optimal co-targeting strategies (target therapy + immunotherapy) for adenoid cystic carcinoma. The postdoctoral fellow will also have the opportunity to be involved in clinical research in head and neck cancers under the direction of Dr. Ferrarotto. The applicants must have a recent Ph.D. and/or M.D. degree with strong research abilities and interests.
The successful candidate will have a track record of productivity in research, and have the talent, energy, passion, commitment and potential to take advantage of the vast resources available at the #1 ranked University of Texas MD Anderson Cancer Center. Excellent verbal and written communication skills, molecular genetics laboratory-based technical skills, reference letters, and strong interest in animal models is required. Expertise in any of the following fields would be considered advantageous but is not essential: PDX/humanized animal models, patient derived organoid culture, biomarkers of response and resistance to cancer therapies (targeted therapies, and immune-based therapies), bioinformatics, and immuno-genomics.
Eligibility Requirements:
The applicants must have a recent Ph.D. and/or M.D. degree with strong research abilities and interests.
Mentor Matching:
This position reports to Renata Ferrarotto, M.D. See Dr. Ferrarotto's research profile.
Additional Application Information:
Interested candidates may send cover letter, CV, and names and contact information of 2-3 references to Kaiyi Li, Ph.D.
Req #: 600657-202109231559
Job Title: Postdoctoral Fellow
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A well-funded, dynamic and question-driven young lab at The University of Texas MD Anderson Cancer Center seeks to appoint one or more highly motivated postdoctoral fellows with a strong interest in cancer biology, tumor immunology and cancer immunotherapy and a desire to work with projects related to lung cancers. The successful appointee(s) will be working under the supervision of Tina Cascone, M.D., Ph.D., Assistant Professor, physician-scientist in the Department of Thoracic/Head and Neck Medical Oncology.
Learning Objectives:
The project and research opportunities for the postdoctoral candidate will focus on investigating T cell-mediated mechanisms of tumor response and resistance to immune-based therapies in non-small cell lung cancer (NSCLC), using innovative preclinical murine models and clinical samples from cutting-edge trials evaluating immune-based therapies for patients with NSCLC. The opportunity to conduct translational research by studying relevant preclinical models and human samples will improve our ability to develop more effective therapeutic strategies for patients with lung cancer and other cancers and advance the field of cancer immunotherapy.
Eligibility Requirements:
Qualified candidates should have a doctoral degree, with strong background in one or more of the following areas: tumor immunology and cancer immunotherapy, molecular biology, cell biology, cancer biology, and biochemistry, with an emphasis on mechanisms of action of immune checkpoint inhibitors and T cell-based therapies (required). Prior experience in understanding, generating, and handling murine models of cancer, as well as ability to analyze data derived from in vivo studies using syngeneic mouse models of cancer is desired. Expertise in any of the following fields would be considered advantageous, but is not essential: oncogenic signaling pathways, biomarkers of response and resistance to cancer therapies (targeted therapies, antiangiogenic therapies and immune-based therapies), cancer metabolism, and immuno-genomics. The postdoctoral fellow is expected to be a self-starter, highly motivated, dedicated, have critical thinking abilities, excellent technical skills, strong work ethic, and excellent organizational and communication skills.
Mentor Matching:
This position reports to Tina Cascone, M.D., Ph.D. See Dr. Cascone's research profile.
Additional Application Information:
For those interested, please send a CV, three letters of recommendation, and a 2-3 page research statement describing past achievement s, skills and research interests to Michelle Morris.
Req #: 600657-202110191809
Job Title: Postdoctoral Fellow
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The Zhang Laboratory in the Department of Thoracic/Head and Neck Medical Oncology, Department of Genomic Medicine, MD Anderson Cancer Center, seeks to fill multiple postdoctoral positions. We closely work with a multidisciplinary team including medical oncologists, surgeons, radiologists, computational biologists, pathologists etc. to obtain and analyze clinicopathological, molecular, radiomics data to understand the molecular mechanisms underlying the development and progression of lung cancers with a focus on tumor heterogeneity in both cancer cells and microenvironment and their impact on cancer biology and patient outcome such as survival and treatment response.
Learning Objectives:
Postdoctoral fellows will benefit from training in analyzing cancer genomic data, immune profiling data, radiomics and histomics data etc. Fellows will have educational opportunities including writing manuscripts/grants and extensive opportunities to gain presentation skills at weekly lab meetings, monthly departmental joint lab meetings and annual conferences (e.g., Keystone, Gordon, Cold Spring Harbor, AACR).
Eligibility Requirements:
Applicants must have a recent (within three years ) Ph.D. and/or M.D. degree with strong research abilities and interests.
Mentor Matching:
This position reports to Jianjun Zhang, M.D., Ph.D. See Dr. Zhang's research profile.
Additional Application Information:
Interested candidates may send cover letter, CV, and names and contact informati on of 2-3 references toDr. Jianjun Zhang.
Req #: 600657-202201111550
Job Title: Postdoctoral Fellow
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Postdoctoral positions are available to study molecular mechanisms associated with therapeutic response and resistance in non-small cell lung cancer (NSCLC) in the laboratory of John V. Heymach, MD, PhD at The University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested in the development of rationale treatment strategies for KRAS, EGFR, and HER2 mutant NSCLC with a focus on overcoming resistance to targeted therapies, identifying targetable metabolic adaptations, and enhancing response to immunotherapy. Applicants with experience in any of these areas are encouraged to apply and provide three professional references.
Learning Objectives:
Trainees will perform translational research involving molecular biology approaches (such as CRISPR/Cas technology,Western blotting, ELISA, immunohistochemistry), in vitro assays (such as drug screening, flow cytometry, development of resistant cell lines, metabolic profiling) and in vivo experiments using xenograft, syngeneic and genetically engineered mouse models of lung cancer. Trainees will present their findings at regular lab meetings, departmental seminars, and national conferences. Trainees will submit their findings for publication in peer-reviewed scientific journals.
Eligibility Requirements:
Applications are invited from qualified individuals, interested in working in a translational research lab; with a PhD and/or MD. Preferred candidate should have less than 2 years of prior postdoctoral experience with background in mouse models studying cancer biology, cell biology, molecular biology, or immunology and be highly moti vated to pursue an independent career in biomedical research.
JOB KNOWLEDGE AND SKILLS:
- Enthusiastic, highly self-motivated candidate, with the ability to function independently
- A strong background in cell and molecular biology, immunology, or metabolic signaling
- Dedication to basic research, a true "drive", is important
- Prior experience with studies involving mice is preferred
- Command of written and spoken English language
- Prior publication record
Program Dates:
Immediately
Mentor Matching:
This position reports to John V. Heymach, M.D., Ph.D. See Dr. Heymach'research profile.
Req #: 600657-202201210837
Job Title: Postdoctoral Fellow
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A postdoctoral position is available to study novel therapeutic targets and molecular mechanisms associated with therapeutic resistance in small cell lung cancer (SCLC) in the laboratory of Lauren Averett Byers, M.D., at The University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested using high-throughput proteomic screening to discover and validate potential drug targets and biomarkers of therapeutic resistance in SCLC.
JOB KNOWLEDGE AND SKILLS: Enthusiastic, highly self-motivated candidate, with the ability to function independently and as part of an interactive team. A strong background in cell signaling, molecular biology, and immunology/immunotherapy. Experience in bioinformatics is preferred. Dedication to basic research, a true "drive", is important. Prior experience with studies involving mice is preferred. Command of written and spoken English language. Prior publication record.
Learning Objectives:
Trainees will perform translational research involving molecular biology approaches, in vitro assays, in vivo experiments using xenograft, syngeneic and genetically engineered mouse models of lung cancer, and bioinformatic based analyses. Trainees will present their findings at regular lab meetings, departmental seminars, and national conferences. Trainees will submit their findings for publication in peer-reviewed scientific journals.Trainees will also be expected to apply for appropriate fellowship awards.
Eligibility Requirements:
Applications are invited from qualified individuals, interested in working in a translational research lab, with a Ph.D. and/or M.D. Preferred candidate should have less than 2 years of prior postdoctoral experience with background in cancer biology, biochemistry, cell biology, or molecular biology and be highly motivated to pursue a career in biomedical research.
Program Dates:
Immediately
Mentor Matching:
This position reports to Lauren Byers, M.D., Ph.D. See Dr. Byers' research profile.
Additional Application Information:
Interested candidates may send CV and cover lett er to Robert Cardnell, Ph.D., at rcardnell@mdanderson.org.
Translational Molecular Pathology
Req #: 149100-202111121559
Job Title: Postdoctoral Fellow
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Program/Position Description:
The newly established Computational Spatial Analyses Pathology (SAP) Program and the Translational Molecular Immunoprrofiling laboratory (TMP-IL) in the Translational Molecular Pathology Department at the University of Texas MD Anderson Cancer Center are seeking a highly motivated postdoctoral fellow to join the team. The successful candidate will help perform cutting-edge research and development interfacing with our scientists and clinicians by developing computational pathology solutions within the e context of immuneprofiling data. We invite a highly motivated and independent-thinking individual.
Learning Objectives:
- To learn aspects of cancer research undertaken in a hospital/research institute
- To perform Spatial Image Analysis of Immunohistochemistry (IHC), multiplex Immunofluorescence (MiF) and Hi-Plex assays for both tissue and blood specimens. Perform spatial digital image analysis of stained slides under the supervision of the directors of the SAP and TMP-IL. The analysis of samples includes different tissue types for biomarker analysis and immunoprofiling of scientific translational research projects of TMP-IL including Alliances, Moonshot projects and grants.
- To learn Data Analysis for translational cancer research. Provides technical expertise, including bioinformatics analysis and data integration to design and develop research projects in an independent manner. Compiles analysis generated, records results in concordance with standard methodology, and submits results to the directors of the SAP and TMP-IL.
- To develop research projects using multiplex methodologies for biomarkers analysis on tissue samples. Develop computational and programming research projects using novel multiplex-based techniques (CODEX, GeoMxDSP, IMC, MIBI) from different tumor types for biomarkers analysis of complex research projects of TMP-IL. Builds results sharing database and computational infrastructure at TMP-IL.
- To understand how studies done in laboratories can have an impact on patient care in the future
- The trainee will learn how to perform advanced statistical and computational analysis on path data
- The trainee along with the mentor will present his/her data in lab meetings.
- The trainee will participate in departmental education activities in particular those offered by ITERT
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Dates or Training Schedule:
TBD
Mentor Matching:
This position reports to Cara Haymaker and Kasthuri Kannan
Requisition Number: 149100-202111121524
Job Title: Postdoctoral Fellow
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Program/Position Description:
Despite recent advances in immunotherapy, lung adenocarcinoma remains the leading cause of death in smokers. There are very few, if any, strategies for early treatment of this disease -- largely due to a very poor understanding of molecular changes that drive its initiation and development. One of our laboratory's goals is to delineate early immune events in the transition of smoking-exposed normal airway to lung adenocarcinoma. Understanding these changes will pave way for the development of new prevention (immune-based) strategies for lung cancer. Our lung cancer program is also actively investigating the role of the host microbiome in lung oncogenesis. We find that knockout of specific host defense and airway lineage genes perturb host microbiome homeostasis concomitant with lung tumor development. We are also eager to mechanistically understand novel cues between airway lineage factors, alveolar reprogramming, and microbiome homeostasis as well as understand the role of the host gut (and possibly the lung) microbiome in the pathogenesis of lung cancer. Our lung cancer research program at the Department of Translational Molecular Pathology is looking for a postdoctoral fellow to embark on different vignettes in the microbiome and immune evolution of lung cancer including understanding the dynamic interplay between host defense (including immunomodulatory) responses, tumor-initiating inflammation and microbiome dysbiosis (local and systemic) in the development of the malignancy. The postdoctoral fellow will also work on understanding the role of lung epithelial reprogramming, in the context of inflammation, in early lung adenocarcinoma development. There will be opportune elements for the candidate postdoctoral fellow at MD Anderson Cancer Center to collaborate with physicians and physician-scientists to gain translational insights from laboratory-based findings. We are seeking a postdoctoral fellow whose motivation and ambition matches these exciting and timely projects. The postdoctoral fellow must have abundant experience in immunology, oncoimmunology, cancer biology, and molecular biology. Technically, the candidate postdoctoral fellow must have abundant/adequate experience in animal modeling and work, flow cytometry, immunohistochemistry/cytochemistry, cell culture as well as basic molecular and cellular biology techniques. Experience in microbial (in vivo) research is a big plus. The candidate postdoctoral fellow is also required to display good to excellent communication skills in English (written and oral) as well as showcase a spirit for teamwork and collaborations with different members of the lung cancer research program.
Learning Objectives:
- Learn uncharted cues and pathways in the inception and development of lung adenocarcinoma (which will likely be applicable to other subtypes of lung cancer or other solid tumors).
- Learn individual roles of immune and epithelial cell subsets and functional states/phenotypes in the development of lung adenocarcinoma.
- Develop a skill for collaboration and translation of laboratory-based findings (e.g., development of markers for outcome and response).
- Acquire skills for progression in academia including but not limited to delivering presentations, writing manuscripts and applying for grants/fellowships.
Eligibility Requirements:
An individual holding a recent (within two years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Dates or Training Schedule:
12 months
Mentor Matching:
This position reports to Humam Kadara, Ph.D.
Req #: 149100-202107260848
Job Title: Postdoctoral Fellow
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The main function of this postdoctoral position is to work in a multidisciplinary research pathology team, focused on scientific projects involving translational correlatives from ongoing clinical trials and retrospective databases investigating genitourinary cancers. The research scientist will develop scientific projects, data management, data analysis and interpretation, as well as scientific communications of the findings. Expertise in histopathology and DNA/RNA extraction are required.
Pathology Technicality Assess and annotate pathology blocks/slides for tumor obtained biospecimen in conjunction with a pathologist. Assist in obtaining pathology blocks from outside institutions and maintain database regarding these specimens.
Data Management
- Create scientific content for immunoprofiling and DNA/RNA analysis protocols involving human tissue specimens, and respond to contingencies, revisions, etc. as needed.
- Assist the PI in data analysis, preparation of manuscripts and grant applications.
- Assist the PI and other members of the research team in ordering, maintaining, and tracking research reagents and equipment.
Laboratory Research Coordination
Assist the PI and other members of the study team to coordinate laboratory research activities and daily lab research operation in conjunction with ongoing clinical studies.
Lab-Specific Technicality
Develop and perform scientific research projects on various tumor types. These projects focus on immunoprofiling, cancer genetics and epigenetics, and liquid biopsy techniques. Provide technical expertise in immunoprofiling studies and tissue/blood DNA/RNA analyses.
Clinical Biospecimen Processing
Collect, annotate, archive, and process biospecimen from ongoing clinical research studies. There will be a focus on blood collection and processing from venipuncture samples and DNA/RNA collection and processing from biopsy and surgery samples.
Other duties as assigned
Learning Objectives:
- Support more senior pathologists and develop research projects independently.
- Learn how to perform digital pathology analysis on IHC, multiplex IF, RNAScope, etc.
- Understand the immune system's role in kidney cancer progression and treatment options.
- Develop a skill for collaboration and translation of laboratory-based findings (e.g., development of markers for outcome and response).
- Acquire skills for progression in academia including but not limited to delivering presentations, writing manuscripts and applying for grants/fellowships.
- Learn aspects of kidney cancer research undertaken in a hospital/research institute.
- Understand how studies done in laboratories can have an impact on patient care in the future.
- Learn how to perform basic statistical analysis on path data.
- The trainee, along with the mentor, will present his/her data in lab meetings.
- The trainee will participate in departmental education activities.
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Program Dates:
11/01/2021 – 10/31/2022
Mentor Matching:
This position reports to Chad Tang, M.D. View Dr. Tang's research profile.
Additional application information:
Please submit resume directly to Dr. Tang at ctang1@mdanderson.org.
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202107291635
Job Title: Postdoctoral Fellow
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This position is designed to support and help educate fresh graduate students, who want to gain additional research training after the graduate program. This position specifically designed for students, who are interested to learn tumor cell biology and tumor immunology.
Learning Objectives:
Postdoc will learn to develop and test a new hypothesis on the role of immune cells in metastasis. In particular, this candidate will examine how tumor suppressive immune cells interact with tumor cells and become a tumor promoting immune cells. Eventually, how the immune cells modulate the tumor cell behaviors and eventually promote metastasis.
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity
Program Dates:
11/01/2021 – 10/31/2022
Mentor Matching:
This position reports to Sendurai Mani, Ph.D. View Dr. Mani's research profile.
Additional application information:
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202108171728
Job Title: Postdoctoral Fellow
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To participate in the development and conduct of a research project to study the roles of small molecules for cancer therapeutics.
Learning Objectives:
- To understand the complex concept of microRNAs targeting messenger RNAs and other RNAs.
- To learn the advanced techniques of cloning, functional studies for microRNAs and their functional characterization
- To learn the advanced techniques in vivo for microRNAs and their functional characterization
- To learn the bioinformatics methods used currently in the non-coding field
- To write fluently in English and to develop in writing complex and innovative concepts necessary for manuscripts, fellowships and grants
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Program Dates:
11/01/2021 – 10/31/2022
Mentor Matching:
This position reports to George Calin, M.D. View Dr. Calin's research profile.
Additional application information:
Please submit CV to George Calin at gcalin@mdanderson.org.
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202109271906
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is immediately available for a highly motivated, recent doctoral graduate interested in translational cancer biology using mouse models and patient samples. The successful candidate will investigate multiple avenues focused on identifying novel therapeutic targets and biomarkers in cholangiocarcinoma and gallbladder carcinoma.
Learning Objectives:
During the fellowship, the candidate will gain experience and expertise in mouse modeling, functional gene validation, executing preclinical trials, and some bioinformatics. Previous high-quality training in these competencies, along with immunohistochemistry, cell culture, and molecular cloning is desirable but not required. The candidate must be self-motivated, ethical, team spirited, and must have good communication, organization, and writing skills.
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Program Dates:
The successful candidate is expected to spend at least a 2-year fellowship, renewable.
Mentor Matching:
This position reports to Lawrence Kwong, Ph.D. View Dr. Kwong's research profile.
Additional application information:
Interested candidates should submit their resume/CV to Dr. Kwong .
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202109291521
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is immediately available for a highly motivated, recent doctoral graduate interested in translational cancer biology using mouse models and patient samples. The successful candidate will investigate multiple avenues focused on identifying novel therapeutic targets and biomarkers in melanoma.
Learning Objectives:
During the fellowship, the candidate will gain experience and expertise in mouse modeling, functional gene validation, executing preclinical trials, and some bioinformatics. Previous high-quality training in these competencies, along with immunohistochemistry, cell culture, and molecular cloning is desirable but not required. The candidate must be self-motivated, ethical, team spirited, and must have good communication, organization, and writing skills.
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Program Dates:
The position will start in Feb/Mar 2022. The successful candidate is expected to spend at least a 2-year fellowship, renewable.
Mentor Matching:
This position reports to Lawrence Kwong, Ph.D. View Dr. Kwong's research profile.
Additional application information:
Interested candidates should submit their resume/CV to Dr. Kwong .
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202109291521
Job Title: Postdoctoral Fellow
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A postdoctoral fellow position is available in the Department of Translational Molecular Pathology under the direct supervision of Dr. Anirban Maitra. The overarchig mission of the Maitra Laboratory is to have a meaningful impact on the lives of people with pancreatic cancer through an improved understanding of the molecular underpinnings of this disease. We have pursued this mission by developing and studying new animal models that recapitulate pancreatic cancer in humans, as well as through innovative translational research conducted on patient-derived models and biospecimens. We are a firm proponent of "learning from every patient" and believe that translational research in this disease needs to have a clear line of sight to the clinic, especially given the urgency for making progress in improving patient outcomes. As part of our translational work, we use large-scale omic analysis, e.g. single-cell RNA, CNV, ATACseq and spatial transcriptomics in animal and human specimens and perform validation studies through multiplex IF, CyTOF and FISH.
Learning Objectives:
Qualfied individuals will demonstrate the potential for research as evidenced by their peer-reviewed publications. He/she will have background in cell biology and expertise in the design experiments and execution of in vitro and in vivo experiments. Have expertise in molecular biology, cell culture of 2D and PDOs, sequencing etc.
Eligibility Requirements:
Applicants must have a recent PhD degree with strong research interests.
Program Dates:
1 year minimum term
Mentor Matching:
This position reports to Anirban Maitra, M..B.B.S View Dr. Maitra's research profile.
Additional application information:
Visit the Translational Molecular Pathology page for more information.
Req #: 149100-202201141821
Job Title: Postdoctoral Fellow
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Seeking to incorporate to our Translational Molecular Pathology Immnunoprofiling Research Laboratory (TMP-IL ) a highly motivated and talented pathologist fellow who is interested in making a difference against cancer and improve patient's outcomes. The Translational Molecular Pathology –Immunoprofiling lab (TMP-IL) translates immunopofiling data into research that is clinically applicable and can aid in the treatment and outcome of future cancer patients. The long-term goal of our laboratory is to elucidate the molecular mechanism in cancer pathogenesis and progression, identifying molecular markers related with tumor development, progression, and metastasis in solid tumors and hematological malignancies. Our laboratory has focused on molecular immune-profiling research on the tumor microenvironment of cancer by IHC, multiplex IF, RNAscope and highplex technologies and pursuing prognostic and predictive molecular biomarkers for chemo and target and immune therapies.
Learning Objectives:
To learn aspects of cancer research undertaken in a hospital/research institute
To learn how to perform digital pathology analysis on IHC, multiplex IF, and RNAScope etc.
To develop research projects using novel multiplex based techniques (CODEX, GeoMxDSP, IMC, MIBI) utilizing FFPE surgical specimens, core needle biopsies and smears from different tumor types for biomarkers analysis of complex research projects of TMP-IL.
To understand how studies done in laboratories can have an impact on patient care in the future
The trainee will learn how to perform basic statistical analysis on path data
The trainee along with the mentor will present his/her data in lab meetings.
The trainee will participate in departmental education activities in particular those offered by ITERT
Eligibility Requirements:
An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Mentor Matching:
This position reports to Ignacio I. Wistuba, M.D. View Dr. Wistuba's research profile.
Additional application information:
Visit the Translational Molecular Pathology page for more information.
Requisition Number: 149100-202201251014
Job Title: Postdoctoral Fellow
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Program/Position Description:
Despite recent advances in immunotherapy, lung adenocarcinoma remains the leading cause of death in smokers. There are very few, if any, strategies for early treatment of this disease -- largely due to a very poor understanding of events that drive its initiation and development. One of our laboratory's goals is to delineate early immune events in the transition of smoking-exposed normal airway to lung adenocarcinoma. Understanding these changes will pave way for the development of new prevention (immune-based) strategies for lung cancer. Our lung cancer program is also actively investigating the role of the host microbiome in lung oncogenesis. We find that knockout of specific host defense and airway lineage genes perturb host microbiome homeostasis concomitant with lung tumor development. We are also eager to mechanistically understand novel cues between airway lineage factors, alveolar reprogramming, and microbiome homeostasis as well as understand the role of the host gut (and possibly the lung) microbiome in pathogenesis of lung cancer. The Kadara Laboratory at the Department of Translational Molecular Pathology has an opening for a postdoctoral fellow to embark on different vignettes in the microbiome and immune evolution of lung cancer including understanding the dynamic interplay between host defense (including immunomodulatory) responses, tumor-initiating inflammation and microbiome dysbiosis (local and systemic) in the development of the malignancy. The postdoctoral fellow will also work on understanding the role of lung epithelial reprogramming, in the context of inflammation, in early lung adenocarcinoma development. There will be opportune elements for the candidate postdoctoral fellow at MD Anderson Cancer Center to collaborate with physicians and physician-scientists to gain translational insights from laboratory-based findings. We are seeking a postdoctoral fellow whose motivation and ambition matches these exciting and timely projects. The postdoctoral fellow must have adequate experience in immunology, oncoimmunology, cancer biology, and molecular biology. Technically, the candidate postdoctoral fellow must have abundant/adequate experience in animal modeling and work, flow cytometry, immunohistochemistry/cytochemistry, cell culture as well as basic molecular and cellular biology techniques. Experience in microbial (in vivo) research is a big plus. The candidate postdoctoral fellow is also required to display good to excellent communication skills in English (written and oral) as well as showcase a spirit for teamwork and collaborations with different members of the lung cancer research program.
Learning Objectives:
- Learn uncharted cues and pathways in the inception and development of lung adenocarcinoma (which will likely be applicable to other subtypes of lung cancer or other solid tumors).
- Learn individual roles of immune and epithelial cell subsets and functional states/phenotypes in the development of lung adenocarcinoma.
- Develop a skill for collaboration and translation of laboratory-based findings (e.g., development of markers for outcome and response).
- Acquire skills for progression in academia including but not limited to delivering presentations, writing manuscripts and applying for grants/fellowships.
Eligibility Requirements:
An individual holding a recent (within two years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.
Dates or Training Schedule:
12 months
Mentor Matching:
This position reports to Humam Kadara, Ph.D..
Additional Application Information:
Visit the Translational Molecular Pathology website.
request an appointment online.
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