Therapeutic Alternatives at M. D. Anderson for Patients with MDS

Leukemia Insights - Winter 2008

Once the diagnosis of MDS is made and the patient is properly classified, the question is what is the best therapy for the patient. In our center, we still classify patients by IPSS score, although we may decide on introducing therapy earlier based on our new models described above. A list with characteristics of our current protocols is available on the M. D. Anderson Web site. The information provided is continuously updated.

Table 2. M. D. Anderson Low Risk MDS Model Scores

Score	N	Median (months)	4-year survival (%)	Category
0	11	NR	78	1
1	58	83	82	1
2	113	51	51	1
3	185	36	40	2
4	223	22	27	2
5	166	14	9	3
6	86	16	7	3
7	13	9	NA	3