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Research Moves Cancer Treatment Forward

Family Matters - Winter 2011

2010 SIOP Conference news

For the first time in 17 years, the United States was the host site for the Annual Congress of the International Society of Pediatric Oncology (SIOP). Several physicians and researchers from MD Anderson Children's Cancer Hospital were selected to present at this year's meeting.

The following is a summary of some of the research highlights from MD Anderson.

Problem-Solving Skills Training Helps Mothers of Newly Diagnosed Patients Cope With Stress

Mothers who have children diagnosed with cancer now have a better approach to address and cope with stresses associated with their child’s disease, according to a study by Martha Askins, Ph.D. A new intervention called Problem-Solving Skills Training (PSST) has proven to be more effective long term compared to other psychological methods, such as reflective listening.

 

Reirradiation for Progressive Diffuse Intrinsic Pontine Glioma

Radiation oncologists from MD Anderson Cancer Center led by Anita Mahajan, M.D., have found a way to safely alleviate symptoms in patients with diffuse intrinsic pontine glioma, an aggressive and fatal pediatric brain cancer.

 

Factors Influencing Adherence to Follow-Up Care in Childhood Cancer Survivors

According to a research study led by Joann Ater, M.D., nearly 80% of children survive their cancer, but two-thirds of those survivors experience late effects from their treatment. Despite their increased risk for late effects such as heart disease, diabetes and secondary cancers, nearly half of childhood cancer survivors at the Children's Cancer Hospital did not continue follow-up care seven years after their diagnosis.

 

Health Behaviors and Preferences of Childhood Cancer Survivors

Approximately 40% of childhood cancer survivors are overweight or obese. Although the growing trend in America is alarmingly similar, cancer survivors are at a higher risk for heart disease, diabetes and other late effects as a result of treatment. Researchers at the Children’s Cancer Hospital led by Joann Ater, M.D., studied the health behavior and preferences of its survivors to determine what can be done to encourage healthier lifestyles.

 

Prognostic Factor Discovered for Pediatric Bone Cancer Survival and Ways to Lower Costs of Care

Peter Anderson, M.D., Ph.D., and other researchers have shown the importance of the absolute lymphocyte count (ALC) in predicting the prognosis of pediatric bone cancer patients. This is built on previous studies of other pediatric populations at 
MD Anderson confirming ALC as a prognostic factor.

 

Comparison Shows Inpatient Chemotherapy More Costly Than Outpatient Delivery

Improvements in the delivery of anti-nausea medication and fluid hydration have allowed for some chemotherapy regimens to be administered in an outpatient setting. Although surveys have shown patients prefer outpatient care compared to inpatient care, a new study conducted by the Children’s Cancer Hospital has further quantified the benefits of outpatient care.

 

Signaling Pathway Impacts Spread of Bone Cancer and Overall Survival

Dennis Hughes, M.D., Ph.D., and other researchers at the Children's Cancer Hospital have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer.

More research information

More information on the research presented at SIOP and other 2010 research can be found on the Children's Cancer Hospital website.


© 2014 The University of Texas MD Anderson Cancer Center