Publications
Lung Cancer: Genes Predict Response to Tarceva
Conquest - Summer 2011
Lauren Averett Byers, M.D., and John Heymach, M.D.,
Ph.D., worked together to better understand gene
response to Tarceva.
Photo: Karen Hensley
Approximately 12% of lung cancer patients benefit from erlotinib, commercially known as Tarceva®. By checking for certain mutations and amplifications of the epidermal growth factor receptor (EGFR), clinicians can identify this group.
Fortunately, recent discoveries show that response to treatment with Tarceva also can be predicted for patients who have no guiding indicators for their treatment.
“Two biomarker sets have potentially broad impact by covering the 88% of patients who lack the EGFR mutations,” says John Heymach, M.D., Ph.D., associate professor in MD Anderson’s Department of Thoracic/Head and Neck Medical Oncology.
Reported in April 2011 at the 102nd Annual Meeting of the American Association for Cancer Research.
Conquest-Summer 2011
Features
Legacy of a President: John Mendelsohn:
- Through Whirlwind and Calm
- Visionary: A Belief in Possibility
- Researcher: A Golden Beacon
- Pioneer: New Approach to Cancer Treatment
- Leader: Growing Our Way to Success
- Ambassador: With Portfolio
- Educator: Key to the Future
- Architect: Structured, Global Relationships
- Fundraiser: On the Money
- Picture This: John Mendelsohn's Office
Nursing:
- Questioning Traditions, Standards, Basics
- Thigh-High Versus Knee-High
- The Undeniable Pressure of Evidence
- Together When They Need Each Other Most
Frontline
- DePinho Next MD Anderson President
- Roadblock Clears Path for Herceptin
- Drugs May Block Metastasis-Driving Protein
- Genes Predict Response to Tarceva
- Another Key to Bladder Cancer Risk
- Also in the News

