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Test Helps Predict Chemotherapy Response

Conquest - Fall 2011


Could Guide Treatment for Breast Cancer Patients

W. Fraser Symmans, 
M.D.

Researchers have developed a new test to predict which patients with newly diagnosed breast cancer have excellent probability of response and survival following chemotherapy.

Using an algorithm combining genomic information from the biopsy of a patient’s tumor, the test identified those for whom standard therapy had high probability of success, as well as those who might benefit from participating in a clinical trial.

“The research builds on a decade of collaborative work in developing a clinically meaningful chemotherapy predictor,” says W. Fraser Symmans, M.D., professor in 
MD Anderson’s Department of Pathology.

“If validated in future studies, it could guide therapy for about 80% of newly diagnosed women with invasive breast cancer who are candidates for chemotherapy,”

Reported in the May 11, 2011, issue of the Journal of the American Medical Association.

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