Conquest - Fall 2008
In 2008, it’s expected that nearly 22,000 new cases of brain or central nervous system tumors will be diagnosed. And, according to the National Cancer Institute, about 13,000 people will die from brain malignancies.
With support from a five-year, $11.5 million Specialized Programs of Research Excellence grant from the NCI, M. D. Anderson researchers hope to take a bite out of those statistics.
The brain tumor SPORE builds on institutional expertise in several departments. Funds from the translational research grant will help advance two new therapeutic approaches for malignant brain tumors, including glioblastoma multiforme, and develop biomarkers to guide treatment decisions.
“All four of the projects funded by this grant apply molecular and genetic approaches to develop new targeted therapies and biomarkers that will improve treatment by personalizing therapy,” says W.K. Alfred Yung, M.D., chair of the Department of Neuro-Oncology and co-principal investigator on the SPORE with Oliver Bogler, Ph.D., associate professor in the Department of Neurosurgery.
Principal investigators: Juan Fueyo, M.D., associate professor, Department of Neuro-Oncology; Frederick Lang, M.D., professor, Department of Neurosurgery.
The SPORE Score:
When it comes to SPOREs,
The Specialized Programs of Research Excellence grant for brain tumor research marks the 11th such award M. D. Anderson has received from the National Cancer Institute — the most held by any institution.
“This award marks a very significant event for M. D. Anderson and indicates the important role that the institution plays in the field of translational research,” says Raymond DuBois, M.D., Ph.D., provost and executive vice president. “We’re essentially leading the way in developing multidisciplinary research teams to accelerate the transition of basic knowledge into the clinic.”
M. D. Anderson’s other SPORE grants are in leukemia and melanoma as well as breast, genitourinary, pancreatic, ovarian, uterine, head and neck, prostate and lung cancers. The lung SPORE is shared with The University of Texas Southwestern Medical Center in Dallas.
Principal investigators: Garth Powis, D.Phil., chair, Department of Experimental Therapeutics; W.K. Alfred Yung, M.D., chair, Department of Neuro-Oncology; Oliver Bogler, Ph.D., associate professor, Department of Neurosurgery.
Principal investigators: Kenneth Aldape, M.D., professor, Department of Pathology; Howard Colman, M.D., Ph.D., assistant professor, Department of Neuro-Oncology.
Principal investigators: Melissa Bondy, Ph.D., professor, Department of Epidemiology; Christina Meyers, Ph.D., professor, Department of Neuro-Oncology.
Conquest - Fall 2008
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Listen to the full publication of Fall 2008 Conquest generously recorded and donated by Taping for the Blind, Inc. The publication is read by Laura Upton.