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Multiple Endocrine Neoplasia Prevention

Screening exams are important medical tests done when you’re healthy and don’t have symptoms. They help find disease at its earliest stage, when the chances for successful treatment are best. If other people in your family have or have had a MEN syndrome, your doctor may suggest tests to find out if you have the disease. Finding a tumor early can help increase your chances for successful treatment.

MEN1

If you have or at risk for MEN1, your doctor may recommend annual screening tests, including:

  • Blood tests for calcium, parathyroid hormone, gastrin and prolactin levels
  • Imaging tests such as ultrasound, CT or MRI to screen for carcinoid, pancreatic, pituitary and other tumors

Screening has been recommended as early as age 5 for children at risk for MEN1.

MEN2

Regular screening for pheochromocytoma allows for early diagnosis and treatment, often before the tumor causes symptoms. Screening should also be done prior to any elective surgery, pregnancy and childbirth. Screening involves either a 24-hour urine collection or a blood test, which measure levels of catecholamines. If screening indicates a pheochromocytoma, an imaging study will be ordered, which may include a CT scan, MRI and/or a special nuclear medicine test called an MIBG study.

All patients with MEN2 should be screened annually or more often if symptoms develop. People with familial medullary thyroid cancer also should be screened because some families classified as FMTC actually have MEN2A.

If you have been diagnosed with multiple endocrine neoplasia, we’re here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.

Why Choose MD Anderson?

  • One of most-active multiple endocrine neoplasia (MEN) programs
  • Personalized team approach to complex conditions
  • Advanced treatments for MEN
  • Genetic testing and counseling
  • Active research program offers clinical trials for multiple endocrine neoplasia

MEN Knowledge Center

Treatment at MD Anderson

Multiple endocrine neoplasias are treated in our:

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MEN Risk Factors

Anything that increases your chance of getting a particular disease is a risk factor.  Multiple endocrine neoplasia is caused by gene mutations that are handed down in families.

  • MEN1 is caused by gene mutations in the MEN1 gene
  • MEN2 is caused by gene mutations in the RET gene

If you have any of the MEN syndromes, your children have a 50% chance of developing the disease. If you or anyone in your family have multiple endocrine neoplasia, tell your doctor. We offer advanced genetic testing to let you know your risk.

MEN Prevention

Research shows that many cancers and related diseases could be prevented if people applied everything known about cancer prevention to their lives. Visit the Prevention section of our website to find out steps you can take to avoid cancer.


© 2014 The University of Texas MD Anderson Cancer Center