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Role of Genetic Mechanisms Associated with Cancer Susceptibility to be Presented at Symposium

Role of Genetic Mechanisms Associated with Cancer Susceptibility to be Presented at Symposium
M. D. Anderson News Release 11/14/00

Nov. 14–17, 2000

J.W. Marriott Hotel
5150 Westheimer Rd.

The role of molecular genetics in cancer susceptibility and development will highlight a symposium here Nov. 14–17 in which top cancer geneticists nationwide will discuss Genetic Mechanisms in Cancer.

The symposium, sponsored by The University of Texas M. D. Anderson Cancer Center, marks the center's 53rd Annual Symposium on Fundamental Cancer Research. Held at the J.W. Marriott Hotel, 5150 Westheimer Rd., the event begins at 4 p.m. Tuesday, Nov. 14, with welcoming remarks at 7 p.m. by
Dr. Frederick Becker, special advisor to Dr. John Mendelsohn, president of M. D. Anderson.

Dr. Becker also will present the Ernst W. Bertner Award to Dr. Charles Sherr, who is from
St. Jude Children’s Research Hospital and a leading expert in cell cycle genetics. The first session, beginning at 8 a.m. Wednesday, Nov. 15, will continue with the theme of cell cycle and signaling pathways (genes controlling cell division).

"The goal of this symposium is to review the current status of cancer genetics and discuss ways to move forward," said Dr. Michael Siciliano, professor of molecular genetics in the Department of Molecular Genetics at M. D. Anderson. Dr. Siciliano also is co-chair of the symposium with Dr. Louise Strong, chief of the Section of Medical Genetics in the Department of Pediatrics at M. D. Anderson.

"Because cancer is a genetic disease, the way genes work — divide or reproduce — is very important to understanding the disease and developing new treatments. By highlighting recent advances in this research and building on them, the distinguished speakers will describe their visions of the future. The symposium will provide a forum for basic scientists to exchange information and foster collaboration," explained Dr. Siciliano, who holds the Kenneth D. Muller Professorship of Tumor Genetics.

In addition, the symposium will focus on topics of genetic models, genetic variation, DNA repair processes and susceptibility, and gene expression. Some additional highlights of the conference are listed below.

Wednesday, Nov. 15

  • 8 a.m., Dr. Stephen Elledge, Baylor College of Medicine, will give an overview of cell cycle checkpoints.
  • 1:30 p.m., Dr. Louise Strong will discuss mechanisms of genetic susceptibility to cancer.

Thursday, Nov. 16

  • 8 a.m., Dr. Geoffrey M. Wahl, The Salk Institute, La Jolla, Calif., will present "Coping with Stress: p53 Mediated Genome Protection and Oncogene-Induced Genetic Instability."
  • 1:30 p.m., Dr. Richard Fishel, Kimmel Cancer Center, Philadelphia, Penn., will open the afternoon session focussing on DNA repair processes.


Friday, Nov. 17


  • 8 a.m., Dr. Jeffrey Trent, National Human Genome Research Institute, Bethesda, Maryland, will present an overview: "Applying Gene Expression Profiling to the Discovery of Cancer Causing Genes."
  • The final conference session, which will focus on mechanisms and variation of gene expression in neoplasia, begins at 8 a.m. with closing comments at noon.

Individuals interested in attending the symposium should call M. D. Anderson's Conference Services Department at 713-792-2222. A copy of the symposium brochure may be found on the Internet at


© 2015 The University of Texas MD Anderson Cancer Center