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Proteomics and Metabolomics Facility

The Proteomics Facility at The University of Texas MD Anderson Cancer Center was founded in 2002.  Metabolomics was added in 2014.

The facility provides state-of-the-art mass spectrometry analysis of proteins and metabolites for both basic and clinical cancer research. We work with internal as well as external researchers.

Please remember to acknowledge your use of the Facility in your publications, and keep us informed when you do so!  

Our Mission

The primary mission of the Proteomics and Metabolomics Facility is to serve the faculty of the MD Anderson Cancer Center by providing access to mass-spectrometry based proteomics and metabolomics technologies and services.

What is the Proteome?

The term proteome was coined in the mid-1990s to describe the set of proteins encoded by the genome.

-ome: Transcriptome, interactome, degradome, metabolome, secretome, etc.

What is Proteomics?

Proteomics is the study of proteomes or the systematic analysis of proteins.

It is pronounced as [pro•te•o•mics] (prOt-E-'O-miks) but not [proteonomics].

As defined by Merriam-Webster dictionary: a branch of biotechnology concerned with applying the techniques of molecular biology, biochemistry and genetics to analyzing the structure, function and interactions of the proteins produced by the genes of a particular cell, tissue or organism, with organizing the information in databases, and with applications of the data (as in medicine or biology).

Proteomics was originally used for the large scale identification of proteins separated by 2D gel electrophoresis. However, proteomics now includes not only the analysis of all expressed protein analysis but also traditional protein structural studies such as protein identification, post-translational modification, protein-protein interactions and other functional interests related with protein structure.

How Can We Help You?

Our primary service is protein identification (please see Services), usually but not only from gel-based samples. Proteins are digested with protease and analyzed by mass spectrometry. In a similar way, we can also attempt to find and localize post-translational modifications. For some experiments a simple molecular weight determination may be sufficient, please call 713-834-6096 or e-mail us at dhawke@mdanderson.org to discuss the specific needs of your project. If your project requires other proteomic analyses we can also help you connect with the appropriate resources.

For metabolomics, please inquire!

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© 2014 The University of Texas MD Anderson Cancer Center