Nuclear Magnetic Resonance Facility
The NMR facility houses two state-of-the-art spectrometers for use in the determination of the structure of small molecules and biological macromolecules, reaction kinetics, macromolecule dynamics, metabolism, etc. Samples are analyzed either by individual users or by Dr. Kaluarachchi, the facility manager.
Contact Kumar Kaluarachchi at 713-792-3779 to schedule training on the instruments or to request the analysis of your samples. Instrument time is scheduled in the NMR laboratory.
Core Grant Citation
This facility is funded by NCI # CA16672. Publications should cite the Core grant in the acknowledgment section, if publications use data generated by the Core facility. Two copies of the publication acknowledging the Core grant should also be submitted to the facility at 1515 Holcombe Boulevard, Unit 36, Houston, TX, 77030.
The figure above depicts a 500 MHz TOCSY spectrum of Ac-pTyr-Leu-Pro-Gln-Thr-Val-NH2, a lead peptide in the development of inhibitors of signal transducer and activator of transcription 3 (Stat3).