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IDH2 Mutation Analysis


To detect and type mutations in exon 4 of the IDH2 gene for differential diagnosis and prognostic stratification of glial tumors and acute myeloid leukemia.


PCR-based DNA sequencing. Also available on the Next Gen Sequencing platforms for Hematological malignancies (CMS53) Exon 4, codons 91-132.

Test parameters

This assay will detect mutations in exon 4. The sensitivity of the assay is 20% of mutant sequence in the background of wild type sequence.

Turnaround Time

10 days

Sample Requirements

5ug purified DNA, or 4-1010 mL peripheral blood, 2-5mL bone marrow aspirate, 5 unstained tissue sections on glass slides along with 1 H&E-stained section.

CPT Codes


© 2014 The University of Texas MD Anderson Cancer Center