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Cytomegalovirus (CMV) Quantitation/Viral Load

Cytomegalovirus (CMV) DNA Detection and Quantitation by Real-Time PCR


Cytomegalovirus is a leading cause of morbidity and mortality in transplant recipients. Severe CMV infection in high risk patients may develop soon after transplantation and without effective treatment, may lead to CMV syndrome, tissue invasive disease, and potential rejection or loss of the graft.

Cytomegalovirus (CMV) DNA Detection and Quantitation by Real-Time PCR assay can reliably monitors Cytomegalovirus (CMV) infection in patients receiving antiviral therapy.


The extraction and quantitation of cytomegalovirus (CMV) DNA in human plasma is done by using the COBAS® AmpliPrep/COBAS® TaqMan® CMV system in which CMV DNA extraction is automated using the COBAS® AmpliPrep instrument with amplification and detection automated using the COBAS® TaqMan® Analyzer. Negative, Low Positive, High Positive and internal controls are included in the assay to monitor any possible amplification inhibitors and eliminate any false positive results.

Results are expressed in CMV DNA IU/ml plasma.

Test Parameters

Reference Values

Target Not Detected

Reportable Range:
The quantification range of this assay is 137 to 9,100,000 IU/mL (2 log to 6 log IU/mL).

Limit of Detection:
37 IU/mL (1.57 log IU/mL).

Turnaround Time:
1-2 days

CPT Codes

© 2015 The University of Texas MD Anderson Cancer Center