Chimerism Assessment by Polymorphic Microsatellite Markers
Pre-transplant Screening
Indication
Determination of hematopoietic engraftment or hematopoietic chimerism after allogenic bone marrow transplantation (BMT).
Methodology
Initial screening of pre-transplant and donor samples involves PCR for eight microsatellite markers to identify an informative marker that can be used for subsequent analysis.
Test Parameters
Peripheral blood samples are required from both donor and recipient.
Turnaround Time
Five to seven working days
Sample Requirements
- 10 ml peripheral blood in purple top tube (EDTA Vacutainer), sent on wet ice
or - 2-5 ml of bone marrow aspirate, sent on wet ice
CPT Codes
83890 (DNA Isolation), 83900, 83909, 83912
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.