The MD Anderson Genetically Engineered Mouse Facility is fully equipped for the efficient production of transgenic and chimeric mice. The facility is comprised of three rooms dedicated for the housing of mice, one for tissue culture use, one for microinjection and embryo manipulations, a DNA prep lab, a cryopreservation lab and a materials/embryo storage area. The microinjection room is equipped with four Leica microinjection scopes and five Leica dissecting scopes. There are two biological safety cabinets along with a double stacked tissue culture incubator located separately in a room dedicated for the purposes of tissue culture. There is also a liquid nitrogen storage system for the preservation of ES cells and cryopreservation of mouse embryos and germplasm. All mice are housed under Specific Pathogen Free conditions in three rooms capable of holding over 2,500 mice.
MD Anderson Cancer Center, Mitchell Basic Sciences Research Building (BSRB)
Access through VetMed and Surgery, Floor 2.
MD Anderson Cancer Center, South Campus Research Building (SCRB)
7555 Fannin at Old Spanish Trail.
Jan Parker-Thornburg, Ph.D.
Manager of the GEMF and MRF
Primary contact person – North
Pronuclear injections, cryopreservation, MRF plasmids and libraries
Zhezong (Charlie) Luo
ES cell culture
Blastocyst injections, MRF mouse resources
Animal care and breeding
VetMed and Surgery, BSRB, Floor 2
Manager of the South Campus GEMF
Primary contact person – South