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Evaluation of Interactive Voice Response System for Monitoring Symptoms after Autologous Transplantation

Principal Investigator: Karen O. Anderson, Ph.D.

Patients who undergo autologous transplantations typically report multiple physical, cognitive and affective symptoms during the acute and post-transplant periods. Consistent systematic symptom assessment using an interactive telephone system may help clinicians identify troublesome symptoms before they become severe enough to warrant a visit to an emergency center or a hospitalization. The randomized clinical trial in the proposed project will allow us to determine if accurate assessment with the IVR system, coupled with feedback to the relevant health care providers, will lead to improved symptom management and enhanced quality of life for patients following autologous transplantation.

Specific Goals

  • To evaluate the efficacy of an interactive voice response (IVR) triage system, as compared to telephone assessment only, in improving symptom management for non-Hodgkin’s lymphoma and multiple myeloma patients during the first year following autologous transplantation
  • To evaluate the efficacy of an interactive voice response (IVR) triage system, as compared to telephone assessment only, in improving the quality of life for non-Hodgkin’s lymphoma and multiple myeloma patients during the first year following autologous transplantation

Methods

Patients who agree to participate in the study will be randomized to the IVR assessment plus triage (intervention) or telephone assessment only (comparison) conditions. Both groups will continue to receive the standard of care treatment that all transplantation patients receive during the posttransplantation period. All patients will complete questionnaires assessing symptoms and quality of life. The patients also will complete a brief assessment of physical function. The symptoms of all patients will be assessed during their hospitalization for the pre-transplant conditioning regimen and transplantation. After discharge from the hospital, the symptom data of patients in the IVR assessment plus triage group will be provided to their MD Anderson Cancer Center physicians and advanced practice nurses. Thus, the IVR assessment plus triage intervention combines accurate assessment with feedback to the relevant health care providers. The IVR system also will “triage” or sort the symptom data of patients in the experimental condition based on symptom severity and frequency. The provider will be notified immediately when a symptom or symptom pattern needs prompt attention.

Measures

The measures include the Brief Pain Inventory (BPI), the Brief Fatigue Inventory (BFI), the MD Anderson Symptom Inventory (MDASI), the MOS 12-Item Short-Form Health Survey (SF-12) and the Profile of Mood States (POMS) and a set of physical function tests.

For more information

Contact Jane Brown, B.S.N., C.R.R.N., at janbrown@mdanderson.org


© 2014 The University of Texas MD Anderson Cancer Center