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Project 5: Genome-Based Marker and Therapy Development in Ovarian Cancer


Note: Bold indicates an investigator affiliated with the MD Anderson Ovarian Cancer SPORE or an Ovarian Cancer SPORE at another institution.

  1. Gray JW, Collins C, Pinkel D, Shayesteh L, Lu Y, Mills GB. Genome scanning and gene discovery in breast and ovarian cancer. In: Pezcoller Foundation Symposia: The Biology of Tumors. Mihich E, Croce C (eds.). Plenum Press,1999 65-72. [no PMID]
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  2. Gray JW, Suzuki S, Kuo WL, Polikoff D, Deavers M, Smith-McCune K, Berchuck A, Pinkel D, Albertson D, Mills GB. Specific keynote: genome copy number abnormalities in ovarian cancer. Gynecol Oncol. 2003; 88:S16-21; discussion S22-4. PMID: 12586079.
  3. Schmandt RE, Broaddus R, Lu KH, Shvartsman H, Thornton A, Malpica A, Sun C, Bodurka DC and Gershenson DM. Expression of c-ABL, c-KIT and PDGFR-b in ovarian serous carcinoma and normal ovarian surface epithelium. Cancer 2003; 98: 758-64. PMID: 12910520.
  4. Sayer RA, Lancaster JM, Pittman J, Gray J, Whitaker R, Marks JR, Berchuck A. High insulin-like growth factor-2 (IGF-2) gene expression is an independent predictor of poor survival for patients with advanced stage serous epithelial ovarian cancer. Gynecol Oncol. 2005 Feb;96(2):355-61. PMID: 15661221.
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  5. Schmandt RE, Bennett M., Clifford SL, Thornton A, Jiang F, Broaddus RR, Sun CC, Lu KH, Sood AK, and Gershenson DM. The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary. Cancer Biol Ther. 2006 Sep;5(9):1136-41. Epub 2006 Sep 28. PMID: 16855388.
  6. Guan Y, Kuo WL, Stilwell JL, Takano H, Lapuk AV, Fridlyand J, Mao JH, Yu M, Miller MA, Santos JL, Kalloger SE, Carlson JW, Ginzinger DG, Celniker SE, Mills GB, Huntsman DG, Gray JW. Amplification of PVT1 Contributes to the Pathophysiology of Ovarian and Breast Cancer. Clin Cancer Res. 2007 Oct 1;13(19):5745-55. PMID: 17908964.
  7. Brown LA, Kalloger SE, Miller MA, Shih IM, McKinney SE, Santos JL, Swenerton K, Spellman PT, Gray J, Gilks CB, Huntsman DG. Amplification of 11q13 in ovarian carcinoma. Genes Chromosomes Cancer. 2008 Jun;47(6):481-9. PMID: 18314909.

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