Clinical Trials
The Pancreatic Cancer Study Group offers patients a wide range of clinical trials for the treatment of pancreatic cancer. Many of these protocols have some combination of surgery, chemotherapy, and radiation. Upon medical evaluation, discuss with your physician which treatment option is best for you, whether it is the current standard of care or a clinical trial. Here is a listing of studies currently recruiting participants:
Potentially Resectable - Surgical Oncology Referral
No current protocols
Adjuvant - Therapy following surgery
ID02-040: A Phase II Trial of Postoperative Cisplatin, Interferon-Alpha, and 5-FU combined with Radiation Treatment for Patients with Resected Pancreatic Adenocarcinoma
Principal Investigator: Peter W. Pisters, M.D.
Locally Advanced Disease
2007-0044: A Phase I Trial of Preoperative Radiotherapy with Concurrent Bevacizumab, Erlotinib, and Capecitabine for Locally Advanced Pancreatic Cancer
Principal Investigator: Sunil Krishnan, M.D.
A Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer
Principal Investigator: Razelle Kurzrock, M.D.
Protocol: ID03-0009
2004-0983: A Phase II Trial of Induction Cetuximab, Gemcitabine, and Oxaliplatin, followed by Radiotherapy with Concurrent Capecitabine and Cetuximab, followed by Maintenance Cetuximab and Gemcitabine for Patients with Locally Advanced Pancreatic Cancer
Principal Investigator: Christopher Crane, M.D.
Untreated Locally Advanced (Unresectable) or Metastatic Disease
2007-0014: A Phase II Trial of Novasoy, Gemcitabine, and Erlotinib in Locally Advanced or Metastatic Pancreatic Cancer
Principal Investigator: James Abbruzzese, M.D.
Previously Treated - Metastatic Disease
One Prior Regimen
2006-0079: A Phase II Study of Bortezomib in Combination with Carboplatin in Patients with Locally Advanced or Metastatic Pancreatic Cancer
Principal Investigator: Gauri Varadhachary, M.D.
2007-0666: A Phase II Study of Erlotinib and RAD001 (Everolimus) in Patients with Previously Treated Advanced Pancreatic Cancer
Principal Investigator: Milind Javle, M.D.
Two Prior Regimens
2007-0666: A Phase II Study of Erlotinib and RAD001 (Everolimus) in Patients with Previously Treated Advanced Pancreatic Cancer
Principal Investigator: Milind Javle, M.D.
Supportive Care
No current protocols
Non-Therapeutic Studies
ID02-447: A Study of Psychosocial Adjustment and Quality of Life of Patients with Pancreatic Cancer
Principal Investigator: Renato Lenzi, M.D.
ID02-139: Pancreatic Cancer Family Study
Principal Investigator: Melissa Bondy, Ph.D.
2007-0193: Screening for Early Pancreatic Neoplasia in High Risk Individuals: The Lustgarten Foundation NCI SPORE Cancer of the Pancreas Screening Study (CAPS 3)
Principal Investigator: Jeffrey H. Lee, M.D.