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Select G&D Publications

Wang Y, Waters J, Leung ML, Unruh AK, Roh W, Chen K, Scheet P, Shi X, Vattathil S, Liang H, Multani A, Zhang H, Zhao R, Michor F, Meric-Bernstam F, Navin NE (2014) Clonal Evolution in Breast Cancer Revealed by Single Cell Genome Sequencing. Nature, In Press.

Venkatanarayan A, Raulji P, Norton W, Chakravarti D, Coarfa C, Su X, Sandur S, Ramirez MS, Lee J, Kingsley CV, Sananikone EF, Rajapakshe K, Naff K, Parker-Thornburg JP, Bankson JA, Tsai KY, Gunaratne PH, Flores ER (2014) IAPP driven metabolic reprogramming induces regression of p53-deficient tumours in vivo. Nature, In Press.

Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X (2014) ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression. Nature 508(7495):263-8. doi: 10.1038/nature13045. PMID: 24590075

Hu Z, Chen K, Xia Z, Chavez M, Pal S, Seol JH, Chen CC, Li W, Tyler JK (2014) Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging. Genes Dev 28(4):396-408. doi: 10.1101/gad.233221.113. PMID: 24532716

Timsah Z, Ahmed Z, Lin CC, Melo FA, Stagg LJ, Leonard PG, Jeyabal P, Berrout J, O'Neil RG, Bogdanov M, Ladbury JE (2014) Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion. Nat Struct Mol Biol 21(2):180-8. doi: 10.1038/nsmb.2752. PMID: 24440983

Lopez AL 3rd, Chen J, Joo HJ, Drake M, Shidate M, Kseib C, Arur S (2013) DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis. Dev Cell 27(2):227-40. PMID: 24120884

Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J (2013) Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A 110(45):18042-51. PMID: 24058167 PMCID: PMC3831485

Suen KM, Lin CC, George R, Melo FA, Biggs ER, Ahmed Z, Drake MN, Arur S, Arold ST, Ladbury JE (2013) Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli. Nat Struct Mol Biol 20(5):620-7. PMID: 23584453 PMCID: PMC4059177

Su X, Gi YJ, Chakravarti D, Chan IL, Zhang A, Xia X, Tsai KY, Flores ER (2012) TAp63 is a master transcriptional regulator of lipid and glucose metabolism. Cell Metab 16(4):511-25. PMID: 23040072 PMCID: PMC3483083

Lin CC, Melo FA, Ghosh R, Suen KM, Stagg LJ, Kirkpatrick J, Arold ST, Ahmed Z, Ladbury JE (2012) Inhibition of basal FGF receptor signaling by dimeric Grb2. Cell 149(7):1514-24. PMID: 22726438

Jackson JG, Pant V, Li Q, Chang LL, Quintás-Cardama A, Garza D, Tavana O, Yang P, Manshouri T, Li Y, El-Naggar AK, Lozano G (2012) p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell 21(6):793-806. PMID: 22698404 PMCID: PMC3376352

Latham JA, Chosed RJ, Wang S, Dent SY (2011) Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination. Cell 146(5):709-19. PMID: 21884933 PMCID: PMC3168986

Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, Barton MC (2010) TRIM24 links a non-canonical histone signature to breast cancer. Nature 468(7326):927-32. PMID: 21164480 PMCID: PMC3058826

Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER (2010) TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature 467(7318):986-90. PMID: 20962848 PMCID: PMC3055799


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