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Genes and Development Ph.D. Program

Basic Science on Cancer and Disease

The Genes and Development Ph.D. Program (G&D) is for students seeking advanced training in biomedical research on the fundamental molecular mechanisms that control growth and cell differentiation, and that cause cancer and other human diseases.

Research in our program labs covers a broad spectrum of modern biomedical interests including Genetics, Genomics and Epigenetics; Cancer Biology; Stem Cells and Development; and Biochemistry and Biomolecular Structure. Diverse experimental systems, including mice, frogs, worms, fruit flies, sea urchins, yeast and human cells, are used by G&D faculty and graduate students to conduct their research.

Located in Houston, Texas, in the heart of the world’s largest medical center, the G&D Program provides an exceptional setting for biomedical research and graduate education. Browse through our pages and you’ll discover an outstanding program that prepares students for successful biomedical research careers in academia, industry and government and other biomedical-related professions.

For more information, please read this message from our program director.

 

Newsworthy

G&D hosts 2-day short course on Genome Targeting and Imaging, January 2014

This January 29-30, the Genes & Development Program will host a special 2-day short course called “Snips & Pics: From Genome Targeting to Imaging” at MD Anderson. The course features talks by noted scientists from across the United States, which are free and open to the public, and hands-on demonstrations for graduate students. More Information

GSBS celebrates 50 years of educating scientists

Dr. Michelle Barton reflects on her first year serving jointly as dean of the Graduate School of Biomedical Sciences (GSBS), and on the 50th anniversary of GSBS. Read more here.

Publications

Shi Lab: Nature, doi:10.1038/nature13045. Wen H, et al. ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression.

Arur Lab: Developmental Cell, October 28, 2013. Lopez AL 3rd, et al. DAF-2 and ERK couple nutrient availability to meiotic progression during Caenorhabditis elegans oogenesis. PMID: 24120884

Ladbury Lab: Nature Structural and Molecular Biology, April 14, 2013. Suen KM, et al. Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli. PMID: 23584453

Flores Lab: Cell Metabolism, October 3, 2012. Su, X et al. TAp63 Is a Master Transcriptional Regulator of Lipid and Glucose Metabolism. PMID: 23040072 PMCID: PMC3483083

Ladbury Lab: Cell, June 22, 2012. Lin CC, et al. Inhibition of Basal FGF Receptor Signaling by Dimeric Grb2. PMID: 22726438

Lozano Lab: Cancer Cell, June 12, 2012. Jackson JG, et al. p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer. PMID: 22698404 PMCID: PMC3376352

Dent Lab: Cell, September 2, 2011. Latham JA, et al. Chromatin signaling of kinetochores: trans-regulation of Dam1 methylation by histone H2B ubiquitination. PMID: 21884933 PMCID: PMC3168986

Barton Lab: Nature, December 16, 2010. Tsai W-W, et al. TRIM24 links a non-canonical histone signature to breast cancer. PMID: 21164480 PMCID: PMC3058826

Flores Lab: Nature, October 21, 2010. Su X, et al. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. PMID: 20962848 PMCID: PMC3055799

Program Communications

Genes and Development Program Brochure (pdf, 8 pages, 2.1 MB)

Genes and Development Annual Newsletters

Genes and Development Student Handbook is in revision. If you have questions, please contact Elisabeth Lindheim, Program Manager, at elindheim@mdanderson.org


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