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Faculty

Faculty members who participate in the Experimental Therapeutics Academic Program are chosen based on their diversity of research expertise in their chosen field. These select individuals are affiliated with various institutions that are part of The University of Texas System – MD Anderson Cancer Center, UT Health Science Center at Houston, UT Medical School at Houston and UT School of Public Health. Among them, they represent more than 20 different departments, institutes or centers – the Center for Targeted Therapy, the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases and the departments of Experimental Therapeutics, Molecular Pathology, Integrative Biology and Pharmacology, Leukemia, Veterinary Sciences and Investigational Cancer Therapeutics – to name just a few.

Listed below is each participating faculty member, along with his/her research interests and contact information.

The University of Texas MD Anderson Cancer Center

  • Bharat Aggarwal, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Modulation of inflammatory pathways by natural products for cancer prevention and treatment
    Phone: 713-794-1817
    E-mail: aggarwal@mdanderson.org
  • Michael Andreeff, M.D., Ph.D.
    Departments of Blood & Marrow Transplantation and Leukemia
    Apoptosis; drug resistance; cell cycle; gene therapy; cancer and leukemia stem cells and microenvironment
    Phone: 713-792-7261
    E-mail: mandreef@mdanderson.org
  • Kumudha Balakrishnan, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Chronic lymphocytic leukemia; Mcl-1; microenvironment; apoptosis; BRC signaling; microRNAs
    Phone: 713-792-3336
    E-mail: kbalakr@mdanderson.org
  • Geoffrey A. Bartholomeusz, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    High throughput screens for target identification and drug development utilizing 3D spheroid models and patient-derived ex-vivo tumor models
    Phone: 713-792-4158
    E-mail: gbarthol@mdanderson.org
  • Jan Burger, M.D., Ph.D.
    Department of Leukemia
    Tumor microenvironment; signaling pathways; development of new therapeutic strategies to overcome stromal cell-mediated drug resistance
    Phone: 713-792-1865
    E-mail: jaburger@mdanderson.org
  • George A. Calin, M.D., Ph.D.
    Center for Targeted Therapy; Center for RNA Interference and Non-Coding RNA; Departments of Experimental Therapeutics
    microRNAs; non-coding RNAs; mechanisms of cancer predisposition; new RNA therapeutics
    Phone: 713-792-5461
    E-mail: gcalin@mdanderson.org
  • Joya Chandra, Ph.D.
    Department of Pediatrics – Research
    Therapeutics-induced apoptosis; proteasome inhibitors; oxidative stress and signaling; leukemias; brain tumors; epigenetically targeted therapeutics
    Phone: 713-563-5405
    E-mail: jchandra@mdanderson.org
  • Francois X. Claret, Ph.D.
    Departments of Molecular Therapeutics and Systems Biology
    Cell signaling; cell cycle control; oncogenes; DNA repair in cancer; targeted cancer therapies; translational oncology research
    Phone: 713-563-4204
    E-mail: fxclaret@mdanderson.org
  • Kirk Culotta, Pharm.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Clinical pharmacology; drug development
    Phone: 713-745-4130
    E-mail: ksculotta@mdanderson.org
  • Giulio F. Draetta, M.D., Ph.D.
    Genomic Medicine and Institute for Applied Cancer Science
    Functional genomics; drug discovery and translational medicine; tumor cell metabolism; cancer stem cells
    Phone: 713-563-8872
    E-mail: gdraetta@mdanderson.org
  • Zhen Fan, M.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Cancer targets; cancer cell signaling and metabolism; antibody engineering and therapeutics
    Phone: 713-794-5221
    E-mail: zfan@mdanderson.org
  • Varsha Gandhi, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Mechanisms of action of anticancer drugs; nucleoside analogues; transcription inhibition; chemoresistance; Bcl-2 antagonists; translational research
    Phone: 713-792-2989
    E-mail: vgandhi@mdanderson.org
  • Elizabeth A. Grimm, Ph.D.
    Department of Melanoma Medical Oncology
    Therapeutics for melanoma; intracellular expression of nitric oxide; cytokines and interleukins; kinase pathway inhibitors
    Phone: 713-792-3667
    E-mail: egrimm@mdanderson.org
  • Walter Hittelman, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Genetic/phenotypic changes driving human multistep tumorigenesis; genetic instability mechanisms; development of cancer therapeutic and preventive strategies
    Phone: 713-792-2961
    E-mail: whittelm@mdanderson.org
  • Peng Huang, M.D., Ph.D.
    Center for Targeted Therapy; Department of Molecular Pathology
    Cancer energy metabolism; mitochondria; ROS; redox signaling; anticancer agents
    Phone: 713-834-6044
    E-mail: phuang@mdanderson.org
  • Gary Johanning, Ph.D.
    Keeling Center for Comparative Medicine and Research; Department of Veterinary Sciences
    Vitamins and resistance to cancer chemotherapy; obesity and cancer; nutrition and gene expression; human endogenous retrovirus expression in cancer
    Phone: 512-332-5211
    E-mail: gljohann@mdanderson.org
  • Eric Jonasch, M.D.
    Department of Genitourinary Medical Oncology
    Renal cell carcinoma; von Hippel Lindau disease; targeted therapy; carcinogenesis; molecular biology; predictive biomarkers
    Phone: 713-563-7232
    E-mail: ejonasch@mdanderson.org
  • Khandan Keyomarsi, Ph.D.
    Department of Experimental Radiation Oncology
    Breast cancer; cell cycle control; drug targeting
    Phone: 713-792-4845
    E-mail: kkeyomar@mdanderson.org
  • Marina Konopleva, M.D., Ph.D.
    Department of Leukemia
    Hypoxia; HIF-1; microenvironment; leukemia; Bcl-2 inhibitors; P13K/AKT signaling
    Phone: 713-794-1628
    E-mail: mkonople@mdanderson.org
  • Jian Kuang, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Cell cycle control; regulation of G2/M transition; protein phosphorylation and dephosphorylation; biological function and regulation of ALIX and ALG-2
    Phone: 713-792-8505
    E-mail: jkuang@mdanderson.org
  • Chun Li, Ph.D.
    Department of Cancer Systems Imaging
    Drug delivery; nanomedicine; molecular imaging
    Phone: 713-792-5182
    E-mail: cli@mdanderson.org
  • Shiaw-Yih (Phoebus) Lin, Ph.D.
    Department of Systems Biology
    DNA damage response; cancer stem cells; biomarkers for cancer early detection; prevention and therapy
    Phone: 713-563-4217
    E-mail: sylin@mdanderson.org
  • Gabriel Lopez-Berestein, M.D.
    Center for Targeted Therapy; Center for RNA Interference and Non-Coding RNA; Department of Experimental Therapeutics
    Nanomedicine; cancer biology; macrophage biology
    Phone: 713-792-8143
    E-mail: glopez@mdanderson.org
  • Anirban Maitra, MBBS
    Department of Pathology
    Pancreatic cancer; experimental therapeutics; mouse models; nanotechnology
    Phone: 713-
    E-mail: amaitra1@mdanderson.org
  • Anshu B. Mathur, Ph.D.
    Department of Plastic and Reconstructive Surgery
    Cell and tissue engineering; nanotechnologies, tissue regeneration
    Phone: 713-563-7568
    E-mail: amathur@mdanderson.org
  • David J. McConkey, Ph.D.
    Departments of Urology and Cancer Biology
    Apoptosis; experimental cancer therapeutics; metastasis
    Phone: 713-792-8591
    E-mail: dmcconke@mdanderson.org
  • Timothy J. McDonnell, M.D., Ph.D.
    Department of Hematopathology
    Cell death; oncogenes; molecular oncology; carcinogenesis
    Phone: 713-794-1368
    E-mail: tmcdonne@mdanderson.org
  • John S. McMurray, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Drug design; chemistry and synthesis of drugs; STAT proteins; peptide mimetics
    Phone: 713-745-3763
    E-mail: jmcmurra@mdanderson.org
  • Jeffrey N. Myers, M.D., Ph.D.
    Departments of Head and Neck Surgery and Cancer Biology
    Head and neck squamous cell carcinoma metastasis; p53 gain of function mutations; mechanisms of resistance to EGFR targeted therapy
    Phone: 713-745-2767
    E-mail: jmyers@mdanderson.org
  • Bulent Ozpolat, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Development of molecularly targeted therapies in solid and hematological cancers
    Phone: 713-563-0166
    E-mail: bozpolat@mdanderson.org
  • William Plunkett, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Response of cells to DNA damage with respect to signaling pathways that regulate cell cycle progression, DNA repair mechanisms and cell death
    Phone: 713-792-3335
    E-mail: wplunket@mdanderson.org
  • Jagannadha K. Sastry, Ph.D.
    Department of Immunology
    HIV-AIDS; cervical cancer; vaccines; cellular immunology; synthetic peptides
    Phone: 713-563-3304
    E-mail: jsastry@mdanderson.org
  • Zahid Siddik, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Drug resistance; DNA damage response; tumor suppressor p53; drug development; platinum drugs
    Phone: 713-792-7746
    E-mail: zsiddik@mdanderson.org
  • Judith A. Smith, Pharm.D.
    Department of Gynecologic Oncology - Research
    Drug/CAM development focusing on pharmacokinetics/pharmacodynamics; drug metabolism, multi-drug resistance; placenta perfusion model, HPLC assay development; gynecologic cancers, HPV
    Phone: 713-500-6408
    E-mail: jasmith@mdanderson.org
  • Anil K. Sood, M.D.
    Center for RNA Interference and Non-Coding RNA; Department of Gynecologic Medical Oncology
    Anti-angiogenesis approaches in cancer; receptor tyrosine kinase regulation; therapeutic use of RNA interference/nanoparticles; molecular therapeutics
    Phone: 713-745-5266
    E-mail: asood@mdanderson.org
  • Christine Stellrecht, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Transcription; breast cancer; colon cancer; cMet tyrosine kinase
    Phone: 713-792-3336
    E-mail: cmstellre@mdanderson.org
  • Elizabeth L. Travis, Ph.D.
    Department of Experimental Radiation Oncology
    Radiation-induced fibrosis; genetic basis of tissue radiation sensitivity and fibrosis; growth factors
    Phone: 713-792-3424
    E-mail: etravis@mdanderson.org
  • Shuxing Zhang, Ph.D.
    Center for Targeted Therapy; Department of Experimental Therapeutics
    Computer-aided drug design; molecular modeling; docking/scoring; QSAR; virtual screening; ADMET; cheminformatics; bioinformatics; drug discovery and development; software engineering
    Phone: 713-745-2958
    E-mail: shuzhang@mdanderson.org
  • Wei Zhang, Ph.D.
    Department of Pathology
    Cancer genomics; tumor suppressor genes; signal transduction; molecular markers; drug response
    Phone: 713-745-1103
    E-mail: wzhang@mdanderson.org
  • Dapeng Zhou, M.D., Ph.D.
    Departments of Melanoma Medical Oncology and Immunology
    Cancer glycomics; immunologic glycomics; immunopathology and immunotherapy
    Phone: 713-792-3134
    E-mail: dzhou@mdanderson.org

The University of Texas Health Science Center at Houston

  • Zhiqiang An, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Antibody therapeutics; drug resistance mechanisms; HER/ErbB signaling pathways; cancer targets
    Phone: 713-500-3011
    E-mail: zhiqiang.an@uth.tmc.edu
  • John F. Hancock, M.A., M.B., BChir, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Mammalian signal transduction; Ras signaling; Ras trafficking; cancer biology; plasma membrane structure and function; drug discovery
    Phone: 713-500-2401
    E-mail: john.f.hancock@uth.tmc.edu
  • Barrett R. Harvey, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Antibody therapeutics and diagnostics; gram-positive pathogenesis prevention; directed evolution; high-throughput selections
    Phone: 713-500-3485
    E-mail: barrett.harvey@uth.tmc.edu
  • Wenliang Li, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Novel cancer targets and drug discovery; signaling transduction
    Phone: 713-500-3363
    E-mail: wenliang.li@uth.tmc.edu
  • Nami McCarty, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Stem cells; cancers; immune regulation
    Phone: 713-500-2495
    E-mail: nami.mccarty@uth.tmc.edu
  • Ba-Bie Teng, Ph.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    microRNA regulation; ribozyme RNA-based therapy; genetic and progenitor cell therapy; cardiovascular diseases; vaccine development; viral vector development
    Phone: 713-500-2443
    E-mail: babie.teng@uth.tmc.edu
  • Dachun Wang, M.D.
    The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases
    Immunogenicity of stem cells; disease modeling/tissue regeneration; cell-to-cell signaling; regulation of distal lung progenitor expansion/differentiation; gene expression profiling
    Phone: 713-500-3608
    E-mail: dachun.wang@uth.tmc.edu

The University of Texas Medical School at Houston

  • Zheng (Jake) Chen, Ph.D.
    Department of Biochemistry and Molecular Biology
    Molecular mechanism of the circadian clock; high-throughput screening and chemical biology
    Phone: 713-500-6284
    E-mail: zheng.chen.1@uth.tmc.edu
  • Peter J. A. Davies, M.D., Ph.D.
    Department of Integrative Biology and Pharmacology
    Mechanism of hormone action; regulation of gene expression; hormonal control of cellular proliferation and molecular basis of retinoid action; regulation of macrophage function; molecular basis of retinoid action; regulation and function of cellular transglutaminases; molecular basis of malignant transformation and cancer
    Phone: 512-237-9414
    E-mail: peter.j.davies@uth.tmc.edu
  • Diane L.M. Hickson-Bick, Ph.D.
    Department of Pathology and Laboratory Medicine
    Cardiac energy metabolism; apoptosis; cardiac ischemia and shock
    Phone: 713-500-5328
    E-mail: diane.l.bick@uth.tmc.edu
  • Yong Li, M.D., Ph.D.
    Department of Pediatric Surgery
    Stem cells; musculoskeletal regeneration; fibrosis
    Phone: 713-500-2438
    E-mail: yong.li.1@uth.tmc.edu
  • Gary C. Rosenfeld, Ph.D.
    Education
    Phone: 713-500-7435
    E-mail: gary.c.rosenfeld@uth.tmc.edu
  • Heinrich Taegtmeyer, M.D., D.Phil.
    Department of Cardiology
    Energy substrate metabolism; protein turnover and metabolic signaling in the heart; heart failure and diabetes
    Phone: 713-500-6569
    E-mail: heinrich.taegtmeyer@uth.tmc.edu

The University of Texas School of Public Health

  • Mary Ann Smith, Ph.D.
    Nephrotoxicity; oxidative stress; renal cell biology; mesangial cells; tubular epithelial cells; cell proliferation
    Phone: 713-500-9236
    E-mail: mary.a.smith@uth.tmc.edu

© 2014 The University of Texas MD Anderson Cancer Center