Clinical Trials
Untreated Mantle Cell Lymphoma:
| 2012-0293 | A Phase 1b Study Combining Ibrutinib with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects with CD20-Positive B-Cell Non-Hodgkin Lymphoma (NHL) |
| 2006-0697 | Bortezomib + R-HyperCVAD alternating with Bortezomib + R-High dose Methotrexate/Cytarabine in Untreated Aggressive Mantle Cell Lymphoma |
Previously Treated Mantle Cell Lymphoma:
| 2012-0377 | A Phase 2, Multicenter, Single-Arm Study to Evaluate the Efficacy and Safety of Single-Agent Bruton’s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Subjects with Mantle Cell Lymphoma Who Progress after Bortezomib Therapy |
| 2009-0057 | Phase II Study of Bortezomib in Combination with Cyclophosphamide and Rituximab for Relapsed/refractory Mantle Cell Lymphoma |
| 2010-0261 | Phase II Study of MK-2206 in Patients with Relapsed Lymphoma |
| 2012-0137 | A Phase 1 Study of IPI-145 in Patients with Advanced Hematologic Malignancies |

