IACS Leadership
Head of Research
Carlo Toniatti, M.D., Ph.D.
Carlo Toniatti joins the Institute for Applied Cancer Science as Head of Research after more than twenty years of experience in basic research, drug discovery and clinical development in both a biotech and a pharmaceutical company environment. He has substantial expertise in oncology and also in gene therapy and RNA- interference, recombinant growth factors and transcriptional regulation.
Throughout his career, Toniatti successfully led multiple programs and cross-functional teams and has gained substantial experience in leading different oncology drug discovery programs—including PARP, Wee1, Chk1 and HDM2 inhibitors programs—from target identification/validation to clinical phase 1-2 trials and in executing on translational research for the therapy of biomarker-defined tumor subtypes. He is also experienced in the management of external collaborations and alliances and in portfolio management.
Toniatti received an M.D. degree at the University of Naples, Italy and a Ph.D. in Molecular and Cellular Biology and Pathology at the University of Naples, Italy.
Institute Leadership
- Giulio Draetta, M.D., Ph.D. - Director
- Lynda Chin, M.D. - Scientific Director
- Carlo Toniatti, M.D., Ph.D. - Head of Research
- Philip Jones, Ph.D. - Head of Drug Discovery
- Eric Devroe, Ph.D. - Executive Director, Strategic Alliances
- Jannik Andersen, Ph.D. - Senior Associate Director, Drug Discovery Biology
- Joseph Marszalek, Ph.D. - Senior Associate Director, Target Validation
- Timothy Heffernan, Ph.D. - Associate Director, Target Discovery
- James Horner, B.S. - Associate Director, Mouse Cancer Models
- Ming-Kuei Jang, Ph.D., - Associate Director, Neurobiology
- Alexei Protopopov, Ph.D. - Associate Director, Oncogenomics
- Jianhua (John) Zhang, Ph.D. - Associate Director, Bioinformatics

