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Clinical Research Protocols

A Phase III Randomized Double-Blind Study to Assess the Efficacy and Safety of Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients with Refractory Advanced Colorectal Cancer (Perifosine 343)

Phase III, FOLFOX or FOLFIRI with Bevacizumab and/or Cetuximab in Patients with Untreated Metastatic Colorectal Cancer

Phase I/II Study of Azacitidine & CAPOX (Capecitabine + Oxaliplatin) in Metastatic CRC Pts Enriched for Hypermethylation of CpG Promoter Islands

Phase I Oral MK_2206 w/AZD6244 w/Locally Advanced or Metastatic Solid Tumors (Dose expansion phase is limited to patients in CRC, PANC & Melanoma Center)

FOLFOX + Cetuximab & Dasatinib in metastatic CRC (Ph II ONLY)

Phase II, Randomized, Double Blind Comparison of CASAD vs. Placebo for the Treatment and Prevention of Diarrhea in Patients with Metastatic Colorectal Cancer

Statin Polyp Prevention Trial in Patients with Resected Colon Cancer

Phase II Randomized Trial of SIR-Spheres, Yttruim Microspheres with Cetuximab Plus Irinotecan for Patients with Advanced Colorectal Cancer Metastases to the Liver

Phase III randomized controlled comparison of open versus laparoscopic total mesorectal excision for locally advanced rectal cancer following neoadjuvant chemoradiation

Biobehavioral Effects of Qigong During Rectal Cancer Treatment

Symptom Research Study:  Prospective Study of Symptoms Related to Oxaliplatin-based Regimens in the Treatment of Colorectal Cancer

Multi-Institutional Colon/Rectal Cancer Outcomes Project Within NCCN

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A Phase I Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX4032 in Patients with Solid Tumors

Phase I Oral MK-2206 w/AZD6244 w/Locally Advanced or Metastatic Solid Tumors (Dose expansion phase is limited to patients in CRC, PANC & Melanoma Cancer)

Randomized, Phase III Study of Brivanib vs. Placebo as Adjuvant Therapy to Trans-Arterial Chemo-Embolization (TACE) in Patients with Unresectable HCC The BRISK TA study

A Phase III Trial of Irinotecan / 5-FU / Leucovorin or Oxaliplatin / 5-FU / Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum

Assessment of the Impact of Systemic Chemotherapy on the Quality of Life (QOL) in Patients with Metastatic Appendiceal Epithelial Neoplasms (AEN)

Biobehavioral Effects of Qigong During Rectal and/or Anal or Prostate Cancer Treatment

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Multi-institutional colon/rectal cancer outcomes project within NCCN

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A Study To Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX4032 in Patients with Solid Tumors

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A Phase I Study of Oral MK-2206 in Combination with Oral AZD6244 in Patients with Locally Advanced or Metastatic Solid Tumors (010-02) 

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A Randomized, Placebo-Controlled, Phase I/2 Study of ARQ 197 in Combination with Irinotecan and Cetuximab in Subjects with Metastatic Colorectal Cancer with Wild-Type KRAS Who Have Received Front-Line Systemic Therapy (ARQ 197-A-U252)

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Phase II, Randomized, Double Blind Comparison of CASAD vs. Placebo for the Treatment and Prevention of Diarrhea in Patients with Metastatic Colorectal Cancer

Phase II Randomized study of SIR-Spheres, Yttrium microspheres with cetuximab plus irinotecan for patients with advanced colorectal cancer metastases to the liver

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Phase III randomized controlled comparison of open versus laparoscopic total mesorectal excision for locally advanced rectal cancer following neoadjuvant chemoradiation

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Clinical trials are research studies that test new cancer drugs, diagnostic procedures and therapies on humans.


© 2014 The University of Texas MD Anderson Cancer Center