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Center for Biological Pathways - 2010 Publications List

2010 High Impact Publication List (Cell/Nature/Science series, i.e., IF>10.00) for the Center for Biological Pathways, including only peer-reviewed publications in which members are either first author or corresponding author.  Members are in bold type.

  1. Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, Xing G, Zhao Y, Lin CH, Tsai SF, Fidler IJ, Hung MC. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling Feb 9;3(108):ra9, 2010.
  2. Gong Z, Kim JE, Leung CC, Glover JN, Chen J
    BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Molecular Cell Feb 12;37(3):438-46, 2010.
  3. Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature Mar 18; 464(7287):374-9, 2010.
  4. Huen MS, Huang J, Leung JW, Sy SM, Leung KM, Ching YP, Tsao SW, Chen J. Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.Molecular Cell. Mar 26;37(6):854-64, 2010.
  5. Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature, Apr 15;464(7291):1058-61, 2010.
  6. Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET. SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Molecular Cell 2010 Apr 23;38(2):191-201, 2010.
  7. Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nature Cell Biology May; 12(5):457-67 (Epub 2010 Apr 11), 2010.
  8. Liu T, Ghosal G, Yuan J, *Chen J, *Huang J. FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. *Co-corresponding authors. Science 2010 Aug 6;329(5992):693-6, 2010.
  9. Lu C, Han HD, Mangala LS, Ali-Fehmi R, Newton CS, Ozbun L, Armaiz-Pena GN, Hu W, Stone RL, Munkarah A, Ravoori MK, Shahzad MM, Lee JW, Mora E, Langley RR, Carroll AR, Matsuo K, Spannuth WA, Schmandt R, Jennings NB, Goodman BW, Jaffe RB, Nick AM, Kim HS, Guven EO, Chen YH, Li LY, Hsu MC, Coleman RL, Calin GA, Denkbas EB, Lim JY, Lee JS, Kundra V, Birrer MJ, Hung MC, Lopez-Berestein G, Sood AK. Regulation of tumor angiogenesis by EZH2. Cancer Cell Aug 9;18(2):185-97, 2010.
  10. Dou H, Huang C, Singh M, Carpenter PB, Yeh ET. Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Molecular Cell Aug 13;39(3):333-45, 2010.
  11. Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature Oct 21;467(7318):986-90, 2010.
  12. Liang K, Esteva FJ, Albarracin C, Stemke-Hale K, Lu Y, Bianchini G, Yang CY, Li Y, Li X, Chen CT, Mills GB, Hortobagyi GN, Mendelsohn J, Hung MC, Fan Z. Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated activation of Src and inactivation of PTEN. Cancer Cell Nov 16;18(5):423-35, 2010.
  13. Wei Y, Chen YH, Li LY, Lang J, Yeh SP, Shi B, Yang CC, Yang JY, Lin CY, Lai CC, Hung MC. CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cell. Nature Cell Biology 13 (1): 87-94 (Epub online December 5, 2010), 2011.
  14. Chang  CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hortobagyi GN, Hung MC. EZH2 promotes expansion of breast cancer tumor initiating cells through activation of RAF-b-catenin signaling.  Cancer Cell (in press), 2010.
  15. Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, Lin CY, Lee HJ, Wang YN, Liu M, Liao HW, Shi B, Lai CC, Bedford MT, Tsai CH, Hung MC. Crosstalk between R1175 methylation and Y1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nature Cell Biology (in press), 2010.
  16. Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu J, Lee HH, Liu M, Chen CT, Yu D, Hung MC. p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulation of miRNAs. Nature Cell Biology (in press), 2010.