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Publications

2011

Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC. Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression. Cancer Cell. 2011 Aug 16;20(2):173-86. PMID:21840483 PMCID: PMC3176728

Navin N, Kendall J, Troge J, Rodgers L, Cook K, Stepansky A, Levy D, Lee Y, Esposito D, Peters A, Muthuswamy L,  McCombie R, Hicks J, Wigler M. Tumor Progression Revealed by Single Cell Sequencing (2011) Nature. PMID 21399628

2010

Navin N, Krasnitz A, Rodgers L, Cook K, Meth J, Kendall J, Riggs M, Eberling Y, Troge J, Grubor V, Levy D, Lundin P,  Månér S, Zetterberg A, Hicks J, Wigler M.  Inferring Tumor Progression from Genomic Heterogeneity. Genome Research. 2010. Jan 20(1):68-80  PMID:19903760 PMCID: PMC2798832

2009

Grubor V, Krasnitz A, Troge JE, Meth JL, Lakshmi B, Kendall JT, Yamrom B, Alex G, Pai D, Navin N, Hufnagel LA, Lee YH, Cook K, Allen SL, Rai KR, Damle RN, Calissano C, Chiorazzi N, Wigler M, Esposito D. Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood. 2009 Feb 5;113(6):1294-30 PMID:18922857

2006

Pelham RJ, Rodgers L, Hall I, Lucito R, Nguyen KC, Navin N, Hicks J, Mu D, Powers S, Wigler M, Botstein D. Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19848-53. PMID:17167050

Navin N, Grubor V, Hicks J, Leibu E, Thomas E, Troge J, Riggs M, Lundin P, Månér S, Sebat J, Zetterberg A, Wigler M. PROBER: oligonucleotide FISH probe design software. Bioinformatics. 2006 Oct 1;22(19):2437 PMID:16740623

Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, Schlicting E, Norton L, Hägerström T, Skoog L, Auer G, Månér S, Lundin P, Zetterberg A.  Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 2006 Dec;16(12):1465-79. PMID:17142309

2005

Hicks J, Muthuswamy L, Krasnitz A, Navin N, Riggs M, Grubor V, Esposito D, Alexander J, Troge J, Wigler M, Maner S, Lundin P, Zetterberg A. High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors. Cold Spring Harb Symp Quant Biol. 2005;70:51-63. PMID:16869738

2004

Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, Månér S, Massa H, Walker M, Chi M, Navin N, Lucito R, Healy J, Hicks J, Ye K, Reiner A, Gilliam TC, Trask B, Patterson N, Zetterberg A, Wigler M. Large-scale copy number polymorphism in the human genome. Science. 2004 Jul 23;305(5683):525-8. PMID:15273396

Thomas EE, Srebro N, Sebat J, Navin N, Healy J, Mishra B, Wigler M. Distribution of short paired duplications in mammalian genomes. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10349-54. Epub 2004 Jul 6. PMID:15240876

2003

Komuro A, Nagai M, Navin NE, Sudol M. WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem. 2003 Aug 29;278(35):33334-41. PMID:12807903

Espanel X, Navin N, Kato Y, Tanokura M, Sudol M. Probing WW Domains to Uncover and Refine Determinants of Specificity in Ligand Recognition. Cytotechnology. 2003 Nov;43 (1-3):105-11 PMID:19003214

 

 

Review Articles

2011

Russnes G, Navin N, Hicks J, Borresen-Dale AL. Insight into the heterogeneity of breast cancer through next-generation sequencing. J Clin Invest. 2011 Oct 3;121(10):3810-8  Epub 2011 Oct 3. PMID:21965338 
PMCID: PMC3195464

Navin N, Hicks J. Future Medical Applications of Single Cell Sequencing in Cancer. Genome Medicine 2011 May 31;3(5):31  PMID:21631906 PMCID: PMC3219072

Blake PM, Decker DA, Glennon TM, Liang YM, Losko S, Navin N, Suh KS. Toward an integrated knowledge environment to support modern oncology. Cancer J. 2011 Jul-Aug;17(4):257-63. PMID:21799334

2010   

Navin N, Hicks, J. Tracing the Tumor Lineage.  Mol Onc. 2010. May 4;4(3):267-283 PMID:20537601 PMCID: PMC2904844


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