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Positions Available

Laboratory Coordinator for Single-Cell Genomics Research

The Navin laboratory at the MD Anderson Cancer Center is seeking a skilled laboratory coordinator to manage the daily operations of the lab and perform experiments related to single-cell sequencing.  The person will report directly to the PI and work closely with graduate students and postdocs on projects to investigating genome evolution and diversity in breast cancer.  This job will entail developing new technologies and protocols in the field of genomics and cancer research.  The person must be meticulous, diligent and highly organized.  Experience with molecular biology techniques and cell culture are required. Experience in next-generation sequencing and/or cytological tissue methods including FISH, LCM and immunocytochemistry are preferred. Ability to perform standard laboratory calculations and proficiency with Microsoft office and excel is required.  Previous experience with human tumor samples including ability to work with FFPE and frozen tissue section is preferred.  The person will also be in charge of ordering, managing budgets and maintaining laboratory equipment and reagents. The individual will work closely with the DNA core sequencing facility and interact with our clinical collaborators at MD Anderson.  Candidates with a Ph.D will be given preference.

Exercises considerable imagination, initiative and inventiveness in planning and executing the details of experiments and in evaluating and interpreting the results. Responsible for major participation in the development and revision of techniques, assembles and operates laboratory apparatus and equipment. Collaborates or assists with supervisor and senior research staff with preparation of reports and grant requests. Supervises technicians in their work and assists them as assigned or delegated.  Works closely with graduate students and postdocs.

Required: Bachelor's degree in one of the natural sciences or related field.
Preferred: Ph.D. or M.D.

Required:  Five years of experience in scientific or experimental research work.

Laboratory environment that may involve occasional exposure to hazardous equipment and materials.

Please send the following documents via email to Dr. Navin.
• Curriculum Vitae

Postdoctoral Fellow in Computational Biology & Statistics

The Navin lab has a position open for a postdoctoral fellow with training in computational biology and statistics. The postdoc will work closely with lab members that routinely generate single cell sequencing data and develop new analytical methods for detecting variants in single cancer cells.  Projects will include developing new multivariate analysis methods for single cell data, applying phylogenetic methods and developing new variant callers. The applicant will be expected to lead their own independent research projects that involve investigating clonal diversity and the evolution of somatic mutations in human cancers, with a strong focus on breast cancer.  The trainee will also work with clinical collaborators and other scientists at the MD Anderson Cancer Center.  The ideal applicant will be highly motivated and have some background in cancer biology.

Training in Unix, programming languages (Perl, Python, C++) and statistical languages (R and Matlab) are preferred.  Background in statistical methods, including multivariate analysis, probability, bayesian statistics and regression are desirable.  Knowledge of tools to analyze next-generation sequencing data is preferred.

Please send the following documents via email to Dr. Navin.
• Curriculum Vitae
• Name and contact information of three references


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MD Anderson Cancer Center is an equal opportunity employer, and does not discriminate on the basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status, except where such distinction is required by law. All positions at MD Anderson are security-sensitive and subject to Texas Education Code 51.215, which authorizes the employer to obtain criminal history record information. MD Anderson Cancer Center is a smoke-free environment.

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