E Lin, M.S.

Senior Statistical Analyst

Degree

M.S. in Biostatistics, University of Minnesota, Minneapolis, MN, 2003

Areas of Interest

Survival analysis
Clinical trial design
Microarray/proteomics data analysis
Statistical programming in SAS, R, S-Plus, Matlab

Peer Reviewed Publications

Shen L, Toyota M, Kondo Y, Lin E, Zhang L, Guo Y, Hernandez NS, Chen X, Ahmed S, Konishi K, Hamilton SR, Issa JP. Integrated genetic and epigenetic analysis indentifies three different subclasses of colon cancer. Proc Natl Acad Sci USA. 2007;104(47):18654-18659.

Borthakur G, Lin E, Faderl S, Ferrajoli A, Wierda W, Giles F, O'Brien S. Low serum albumin level is associated with cytomegalovirus reactivation in patients with chronic lymphoproliferative diseases treated with alemtuzumab (campath-1H)-based therapies. Cancer. 2007;110(11):2478-2483.

Baser S, Onn A, Eapen GA, Lin E, Morice RC, Duvic M. Pulmonary Manifestations in Patients with Cutaneous T-cell Lymphomas. Cancer. 2007;109(8):1550-1555.

Pelloski CE, Lin E, Zhang L, Yung WKA, Colman H, Liu JL, Woo SY, Heimberger AB, Suki D, Prados M, Chang S, Barker FG, Fuller GN, Aldape KD. Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res. 2006;12(13):3935-3941.

Guo M, Sneige N, Silva EG, Jan YJ, Cogdell DE, Lin E, Luthra R, Zhang W. Distribution and viral load of eight oncogenic types of human papillomavirus (HPV) and HPV 16 integration status in cervical intraepithelial neoplasia and carcinoma. Mod Pathol. 2007;20(2):256-266.

Baser S, Shannon VR, Eapen GA, Jimenez CA, Onn A, Lin E, Morice RC. Smoking cessation after diagnosis of lung cancer is associated with a beneficial effect on performance status. Chest. 2006;130(6):1784-1790.

Baser S, Shannon VR, Eapen GA, Jimenez CA, Onn A, Keus L, Lin E, Morice RC. Pulmonary dysfunction as a major cause of inoperability among patients with non-small-cell lung cancer. Clin Lung Cancer. 2006;7(5):344-349.

Ramaswamy A, Lin E, Chen I, Mitra R, Morrisett J, Coombes K, Ju Z, Kapoor M. Application of protein lysate microarrays to molecular marker verification and quantification. Proteome Sci. 2005;3:9.

Oida Y, Gopalan B, Miyahara R, Inoue S, Branch CD, Mhashilkar AM, Lin E, Bekele BN, Roth JA, Chada S, Ramesh R. Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer. Mol Cancer Ther. 2005;4(2):291-304.

Jiang H, Gomez-Manzano C, Alemany R, Medrano D, Alonso M, Bekele BN, Lin E, Conrad CC, Yung WKA, Fueyo J. Comparative effect of oncolytic adenoviruses with E1A or E1B-55 kDa deletions in malignant gliomas. Neoplasia. 2005;7(1):48-56.

Abstracts for Conferences

Leung K, Thirumurthi S, Ross WA, Lin E, Lee JH. The prognostic value of endoscopic ultrasound parameters, serum tumor markers, cyst fluid tumor markers, and cyst fluid viscosity in pancreatic cyst neoplasms. Digestive Disease Week Conference. Washington, DC, 2007.

Kesmodel SB, Ellis LM, Lin E, Chang G, Abdalla EK, Kopeta ES, Vauthey JN, Rodriguez-Bigas MA, Curley SA, Feig BW. Preoperative bevacizumab does not increase postoperative complications in patients undergoing hepatic surgery for colorectal cancer liver metastases. The Society of Surgical Oncology’s 2007 Annual Cancer Symposium. Washington, DC, 2007.

Arrossi A, Lin E, Moran C. Histologic assessment and prognostic factors of malignant pleural mesothelioma treated with extrapleural pneumonectomy. United States and Canadian Academy of Pathology 96th Annual Meeting. San Diego, CA, 2007.

Zager JS, Gershenwald JE, Aldrink J, Lin E, Cormier JN, Cheng T, Yoo J, Lee JE, Tyler DS, Ross MI. Isolated limb infusion for locally recurrent and in-transit extremity melanoma: A combined institutional initial experience. Ann Surg Oncol. 2006;84-84.

Weston BR, Ross WA, Lin E, Wang X, Lee JH. What happens to serum carbohydrate antigen 19-9 after biliary stent placement in pancreaticobiliary malignancy? College’s 71st Annual Scientific Meeting. Las Vegas, Nevada, 2006,

Thomas E, Payne L, Caraway NP, Khanna A, Zhang HZ, Lin E, Keating MJ, Katz RL. Chomosomal abnormalities detected by multicolor fluorescence in situ hybridization in lymph node aspirates from patients with small lymphocytic lymphoma are useful for predicting outcome. American Society of Cytopathology 54th Annual Scientific Meeting. Toronto, Ontario, Canada, 2006.

Khanna A, Dawlett M, Katz RL, Lin E, Caraway NP. Fluorescence in situ hybridization detects amplifications of the human telomerase gene in preneoplastic cervical lesions on cytologic preparations and is associated with higher-grade lesion. Cancer Cytopathol. 2006;108:392-393.

Cabanillas ME, Thomas DA, Waguespack SG, Lin E, Huang X, Palmer JL, Busaidy NL, Foundray MC, Cassat JL, Lawson A, Escalante CP, Kantarjian HM, Gagel R. Spectrum of hormone abnormalities contributing to bone loss in adult patients with acute lymphocytic leukemia (ALL) and lymphoblastic lymphoma. The 28th Annual Meeting of American Society of Bone and Mineral Research. Philadelphia, PA, 2006.

Andtbacka RH, Bedrosian I, Ross MI, Lin E, Prieto VG, Aloia TA, Cormier JN, Lee JE, Mansfield PF, Gershenwald JE. AJCC nodal factors and microscopic tumor burden predict recurrence in sentinel lymph node positive stage III melanoma patients. Surgical Oncology Meeting. San Diego, CA, 2006.

Zager JS, Al-Refaie WB, Khakpour N, Yen T, Lin E, Stephens T, Hunt KK, Kuerer HM, Singletary ES, Ross MI, Babiera GV. The utility of ultrasound in the surgical management of ductal carcinoma in situ. 27th Annual San Antonio Breast Cancer Symposium. San Antonio, TX, 2005.

Zager JS, Al-Refaie WB, Hunt KK, Khakpour N, Kuerer HM, Lin E, Yen T, Stephens T, Feig BW, Ames FC, Singletary SE, Ross MI, Babiera GV. Is ultrasound useful in the management of patients with ductal carcinoma in situ? Breast Cancer Res Treat. 2005;S209-S209.

Shen L, Kantarjian H, Saba H, Lin E, Berry D, Ahmed S, Jelinek J, Issa JJ. CpG island methylation is a poor prognostic factor in myelodysplastic syndrome patients and is reversed by decitabine therapy–results of a phase III randomized study. The 2005 American Society of Hematology Annual Meeting. Atlanta, GA, 2005.

Pelloski CE, Yung WA, Colman H, Zhang L, Lin E, Woo SY, Yang H, Ledoux A, Aldape KD. EGFRvIII expression defines a distinct subtype of glioblastoma: A study of 268 patients. Int J Radiat Oncol Biol Phys. 2005;S68-S68.

Baser S, Shannon VR, Eapen GA, Jimenez CA, Onn A, Morice L, Lin E. Impact of pulmonary dysfunction as a cause of inoperability for patients with non-small cell lung cancer. Chest. 2005;334S-335S.

Baser S, Onn A, Jimenez CA, Eapen GA, Shannon VR, Keus L, Morice RC, Lin E. Effect of pulmonary dysfunction on survival and performance in patients with non-small cell lung cancer. Chest. 2005;335S-335S.

Baser S, Eapen GA, Jimenez CA, Onn A, Shannon VR, Keus L, Morice RC, Lin E. Effect of smoking cessation after diagnosis of lung cancer on performance status and survival. Chest. 2005;334S-334S.

Armstrong C, Oakes JM, Jacobs DR, Duval SJ, Lin E, Luepker RV, Arnett D. Social support measures in assessing CVD risk factors: The Minnesota Heart Survey. American Heart Association Scientific Sessions. New Orleans, LA, 2004.

Manuscripts in Preparation

Cabanillas ME, Thomas D, Murphy W, Cassat J, Lin E, Huang X, Mattiuzzi GN, Foudray MC, Kantarjian H, Gagel R. Metabolic bone disease and vitamin D deficiency among patients with newly diagnosed acute lymphoblastic leukemia and lymphoblastic lymphoma.

Guo M, Sneige N, Gong Y, Deavers M, Silva E, Jan YJ, Zhang W, Cogdell D, Lin E, Luthra R. Comparision of in situ hybridization with PCR for human papillomavirus detection, viral load, and HPV16 integration status in cervical carcinoma and cervical intraepithelial neoplasia.

Kim YB, Lin E, Liu J. The significance of biomarkers predicting platinum resistance and overall survival in advanced epithelial ovarian cancer.

Shih LN, Coombes K, Yokoi K, Hawke D, Byrd J, Koomen J, Kobayashi R, Lin E, Xiao LC, Fidler IJ, Hamilton SR. Influence of tumor type and anatomic site of involvement on serum peptidomic biomarkers in a nude mouse xenograft model.

Presentations

Updated June 2, 2009

Our Publications