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Melanoma Title Graphic
Melanoma Basics

Melanoma is a malignant form of skin cancer that occurs in cells called melanocytes, which produce pigments that give skin its color. Melanoma usually appears as an irregular brown, black and/or red spot, or an existing mole that begins to change color, size or shape. While melanoma only represents about 3% of all skin cancers, it has the highest death rate of all types, and is more likely to metastasize (spread).

Melanoma appears most frequently on the trunk area in fair-skinned men and on the lower leg in fair-skinned women. In dark-skinned people, melanoma appears most frequently on the palms, the soles of the feet and the skin under nails. If caught early, melanoma is potentially curable.

Symptoms of Melanoma
Any pigmented lesion that undergoes a change in size, configuration, or color should be biopsied. The ABCDEs of early diagnosis are an easy way to become familiar with the early signs of malignant melanoma:

  • Asymmetry of lesion
  • Border irregularity
  • Color variegation
  • Diameter greater than 6 millimeters
  • Elevation: is the lesion growing in height?
Melanoma Treatment at M. D. Anderson

Request an Appointment
Submit our
Online Self-Referral Form or call 1-877-MDA-6789.

Clinical Trials
Learn about our open melanoma clinical trials by searching our online database.

Patients with melanoma are treated in our Melanoma & Skin Center.
Head and neck melanoma patients are treated in our
Head & Neck Center.

Skin Evaluation Clinic
If you think you may have skin cancer, screening is your best defense.

Minimally Invasive Surgery at M. D. Anderson is a surgical approach to melanoma and other cancer treatments designed to minimize trauma, maximize outcomes and enable patients to quickly return to their normal life.

Melanoma Screening & Prevention

M. D. Anderson's Screening Guideline
(Updated December 2006)

Promptly show your doctor any:

  • Suspicious skin area
  • Non-healing sore
  • Change in a mole or freckle

Skin Chart
Print out this
skin chart (pdf) and mark your moles, freckles, blemishes, birthmarks and other skin growths once a month. If you detect changes, contact your physician.

Skin Cancer Prevention and Early Detection Tips

  • Southern Exposure - Skin cancer prevention tips.
  • Get to Know Your Moles - Spending a few minutes becoming familiar with your moles and learning how to distinguish normal moles from possibly abnormal growths is the key to early detection of skin cancer.
  • How to do a Skin Self-Exam - Follow these easy step-by-step instructions.
Melanoma Education & Support

video iconMelanoma & Skin Cancer (May 2008)

Patient Power - Advances in the Treatment of Melanoma (1:01:16)
The incidence of melanoma, a malignant form of skin cancer, is rising faster than any other cancer. Learn about new advances in treatment including vaccine therapy.(May 2008)
Download  /  Listen

video iconCancer Newsline: Metastatic Melanoma (2:15)
Researchers at M. D. Anderson are studying a monoclonal antibody to treat metastatic melanoma – without the toxic side effects of chemotherapy. (Spring 2005)
Windows Media:
256K / 56K
QuickTime:
256K / 56K

Patient Story

  • Sandy Pierce: "I view it as my greatest accomplishment that I fought cancer, kept my sense of humor and I'm still here today."

Survivor Support

Project Safety - Skin cancer education materials for schoolteachers at all grade levels.

Practice Guidelines - Select Skin, then Melanoma.

Melanoma SPORE - Learn about the Melanoma SPORE, that will look into promising leads in the areas of risk, genetics, biology of progression, immunity and novel therapies.

News & Articles

Plan it Safe, Protect Your Skin for Days in the Sun

Interleukin-12 Indicates Survival Prospects for Melanoma Patients

Test Your Knowledge About Sunscreen

Melanoma Places Athlete in Run for His Life

Q&A: What to Know About Melanoma

Cancer Vaccine Works Through Immune System

Melanoma Risk Only Partially Linked to UVB

Understanding the Basics of Melanoma (Español)

Spice Blocks Melanoma Growth in Lab Tests

More...


Our monthly online cancer publication
Go to
this month's issue


How to Help Graphic
You may give to melanoma research programs with our
Online Donation Form.


askMDAnderson about Cancer

A cancer diagnosis comes with many questions. askMDAnderson has answers.
1-877-MDA-6789
International patients call:
(713) 745-0450

www.mdanderson.org/ask
En Español

Links & Resources

NOTE: Pages will open in a new browser window. M. D. Anderson does not endorse external sites.

American Cancer Society

National Cancer Institute

American Melanoma Foundation

Melanoma International Foundation

NCCN Patient Guidelines (Español)

Melanoma Patients Information Page (MPIP)

U.S. News Cancer Center: Skin Cancer

   

©2008 The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX 77030
1-800-392-1611 (USA) / 1-713-792-6161   (5)

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