Skip to Content

About Us

Anti-Virus Software

Step-by-Step Instructions for Trend Micro Internet Security

Remember: There should only be one anti-virus/spyware program installed on your computer at a given time. If you currently have another anti-virus/spyware program installed on your computer, and wish to use Trend Micro Internet Security as your anti-virus/anti-spyware program. It is highly recommended that you uninstall the other anti-virus/anti-spyware program before attempting to install Trend Micro Internet Security. Please consult with your current anti-virus/anti-spyware provider for complete uninstall instructions.

Step #1: Obtain Serial Number

  • Complete the Online Serial Number Request.  
    Note - After you submit the form, you'll receive an e-mail message containing a link to the serial number.
  • Each serial number is good for 3 different computers, one primary and two secondary computers.
  • Each serial is good for 365 days after registration of the primary computer with Trend Micro
  • You will need to request a new serial number annually.  

Step #2

New Installation

Trend Micro Internet Security fresh installation instructions:
Download the installer file from Trend Micro via the link below and save it on your Desktop.

For TIS 2008
Trend Micro Internet Security 2008 Readme and Installer files

Upgrading Trend Micro Internet Security

How to upgrade the old version of Trend Micro PC-cillin Internet Security to Trend Micro Internet Security

Step #3: Replacing an expiring serial number

For TIS [PC-cillin 2007]

How can I change the serial number of Trend Micro [PC-cillin] Internet Security 2007? To change manually update serial number using the Registry Editor:

  1. Click Start
  2. Click Run
  3. Type regedit, click Ok
  4. Click (+) sign of HKEY_LOCAL_MACHINE
  5. Click (+) sign of Software
  6. Click Trend Micro folder
  7. Click PC-cillin folder
  8. On the right side of the window, right click Serial number then click Modify
  9. Type in the new serial number
  10. Close the Registry window
  11. Open Trend Micro program and then click Update Now button

For TIS 2008

How to change the serial number of Trend Micro Internet Security 2008

Step #4: Registration

A single-user serial number allows the registration of Trend Micro Internet Security on three (3) different computers.

For TIS [PC-cillin 2007]

For TIS 2008

Step #5: Support


© 2009 The University of Texas M. D. Anderson Cancer Center